{ "date": "Wed Dec 1 19:40:38 EST 2021", "pathways": [ { "glytoucan_ac": "G00026MO", "notes": [], "error": "No pathways for [G00026MO] could be generated at this time" }, { "glytoucan_ac": "G00028MO", "notes": [], "error": "No pathways for [G00028MO] could be generated at this time" }, { "glytoucan_ac": "G00176HZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00231WL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19469VZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G19469VZ", "dp": 18 }, { "id": "G00231WL", "dp": 18 } ], "links": [ { "target": "G00231WL", "source": "G19469VZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19469VZ", "source": "G92574YO", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00247PL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42477ZH]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G00247PL", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G00279YF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29434RB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G00279YF", "dp": 9 } ], "links": [ { "target": "G00279YF", "source": "G29434RB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00320ZP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G00320ZP] could be generated at this time" }, { "glytoucan_ac": "G00335DM", "notes": [], "error": "No pathways for [G00335DM] could be generated at this time" }, { "glytoucan_ac": "G00349CA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59942FB]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G56748EO", "dp": 10 }, { "id": "G59942FB", "dp": 11 }, { "id": "G00349CA", "dp": 11 } ], "links": [ { "target": "G00349CA", "source": "G59942FB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59942FB", "source": "G56748EO", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00361YF", "notes": [], "error": "No pathways for [G00361YF] could be generated at this time" }, { "glytoucan_ac": "G00383KP", "notes": [], "error": "No pathways for [G00383KP] could be generated at this time" }, { "glytoucan_ac": "G00383YF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G74574VX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G74574VX", "dp": 11 }, { "id": "G00383YF", "dp": 11 } ], "links": [ { "target": "G00383YF", "source": "G74574VX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74574VX", "source": "G27123NH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00413UF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 } ], "links": [ { "target": "G00413UF", "source": "G84376FR", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00432WV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36523TZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G36523TZ", "dp": 12 }, { "id": "G00432WV", "dp": 12 } ], "links": [ { "target": "G00432WV", "source": "G36523TZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36523TZ", "source": "G29857RC", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00433KW", "notes": [], "error": "No pathways for [G00433KW] could be generated at this time" }, { "glytoucan_ac": "G00463XD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G59277TZ", "dp": 10 } ], "links": [ { "target": "G00463XD", "source": "G59277TZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G59277TZ", "source": "G30159WR", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00470UO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G12061IK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G00470UO", "dp": 11 } ], "links": [ { "target": "G00470UO", "source": "G12061IK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00480KJ", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G26795PW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G11929CD", "dp": 10 }, { "id": "G26795PW", "dp": 11 }, { "id": "G00480KJ", "dp": 11 } ], "links": [ { "target": "G00480KJ", "source": "G26795PW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26795PW", "source": "G11929CD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G11929CD", "source": "G09782JM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00492CQ", "notes": [], "error": "No pathways for [G00492CQ] could be generated at this time" }, { "glytoucan_ac": "G00503EE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00536FZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G00536FZ", "dp": 12 }, { "id": "G00503EE", "dp": 12 } ], "links": [ { "target": "G00503EE", "source": "G00536FZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00536FZ", "source": "G71679MX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00504PZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G72718TT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G00504PZ", "dp": 9 } ], "links": [ { "target": "G00504PZ", "source": "G72718TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00514XC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G00514XC] could be generated at this time" }, { "glytoucan_ac": "G00531ZU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23340ZN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G71835BN", "dp": 10 }, { "id": "G01378OV", "dp": 11 }, { "id": "G23340ZN", "dp": 12 }, { "id": "G00531ZU", "dp": 12 } ], "links": [ { "target": "G00531ZU", "source": "G23340ZN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23340ZN", "source": "G01378OV", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01378OV", "source": "G71835BN", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G71835BN", "source": "G36191CD", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00536FZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 } ], "links": [ { "target": "G00536FZ", "source": "G71679MX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00582VL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G00591PZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G00591PZ] could be generated at this time" }, { "glytoucan_ac": "G00606LX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G70830AN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G00606LX", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G00646SN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G02934UB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 }, { "id": "G02934UB", "dp": 14 }, { "id": "G00646SN", "dp": 14 } ], "links": [ { "target": "G00646SN", "source": "G02934UB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02934UB", "source": "G99074EO", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00662IB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G00662IB] could be generated at this time" }, { "glytoucan_ac": "G00666EC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G00666EC] could be generated at this time" }, { "glytoucan_ac": "G00695JO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G00706AL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53396PX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 }, { "id": "G53396PX", "dp": 14 }, { "id": "G00706AL", "dp": 14 } ], "links": [ { "target": "G00706AL", "source": "G53396PX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53396PX", "source": "G82050MN", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00706QN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27188NC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G27188NC", "dp": 8 }, { "id": "G00706QN", "dp": 8 } ], "links": [ { "target": "G00706QN", "source": "G27188NC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G27188NC", "source": "G07483YN", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00738BQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G00738BQ", "source": "G11041DA", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00741NZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46213JU]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G46213JU", "dp": 10 }, { "id": "G00741NZ", "dp": 10 } ], "links": [ { "target": "G00741NZ", "source": "G46213JU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46213JU", "source": "G16828VN", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00743WU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 } ], "links": [ { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00797ZX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G00797ZX] could be generated at this time" }, { "glytoucan_ac": "G00805TZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75671DO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G00805TZ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G00826SV", "notes": [], "error": "No pathways for [G00826SV] could be generated at this time" }, { "glytoucan_ac": "G00850LT", "notes": [], "error": "No pathways for [G00850LT] could be generated at this time" }, { "glytoucan_ac": "G00876GU", "notes": [], "error": "No pathways for [G00876GU] could be generated at this time" }, { "glytoucan_ac": "G00883DO", "notes": [], "error": "No pathways for [G00883DO] could be generated at this time" }, { "glytoucan_ac": "G00883ZT", "notes": [], "error": "No pathways for [G00883ZT] could be generated at this time" }, { "glytoucan_ac": "G00888JR", "notes": [], "error": "No pathways for [G00888JR] could be generated at this time" }, { "glytoucan_ac": "G00900AZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G64669AQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 }, { "id": "G00900AZ", "dp": 8 } ], "links": [ { "target": "G00900AZ", "source": "G64669AQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G00909GK", "notes": [], "error": "No pathways for [G00909GK] could be generated at this time" }, { "glytoucan_ac": "G00909PI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 } ], "links": [ { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00910WD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G99533GU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 }, { "id": "G28106CM", "dp": 17 }, { "id": "G99533GU", "dp": 18 }, { "id": "G00910WD", "dp": 18 } ], "links": [ { "target": "G00910WD", "source": "G99533GU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99533GU", "source": "G28106CM", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00923KH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G70511VE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G70511VE", "dp": 12 }, { "id": "G00923KH", "dp": 12 } ], "links": [ { "target": "G00923KH", "source": "G70511VE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70511VE", "source": "G53752TA", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00948WV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G17689DH", "dp": 12 }, { "id": "G72578SV", "dp": 13 } ], "links": [ { "target": "G00948WV", "source": "G72578SV", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G72578SV", "source": "G17689DH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00951UF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G79198BK", "dp": 9 } ], "links": [ { "target": "G00951UF", "source": "G79198BK", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G79198BK", "source": "G10219AA", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00966RI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21679ID]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G21679ID", "dp": 11 }, { "id": "G00966RI", "dp": 11 } ], "links": [ { "target": "G00966RI", "source": "G21679ID", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21679ID", "source": "G52934AK", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00978TF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G69411IG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G00978TF", "dp": 7 } ], "links": [ { "target": "G00978TF", "source": "G69411IG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G00982QD", "notes": [], "error": "No pathways for [G00982QD] could be generated at this time" }, { "glytoucan_ac": "G00986YT", "notes": [], "error": "No pathways for [G00986YT] could be generated at this time" }, { "glytoucan_ac": "G00995HW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30483FB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G00995HW", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G00998NI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78059CC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G00998NI", "dp": 10 } ], "links": [ { "target": "G00998NI", "source": "G78059CC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01001RL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G01010HW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 } ], "links": [ { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01028FJ", "notes": [], "error": "No pathways for [G01028FJ] could be generated at this time" }, { "glytoucan_ac": "G01034MJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40064GR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G01034MJ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G01069AK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G01069AK", "source": "G91365ZQ", "residue_affected": { "residue_id": "N216", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01169EW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65597BI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 }, { "id": "G01169EW", "dp": 10 } ], "links": [ { "target": "G01169EW", "source": "G65597BI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01220PX", "notes": [], "error": "No pathways for [G01220PX] could be generated at this time" }, { "glytoucan_ac": "G01223IC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G01244DB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 } ], "links": [ { "target": "G01244DB", "source": "G77252PU", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01260KO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G86270DU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G86270DU", "dp": 12 }, { "id": "G01260KO", "dp": 12 } ], "links": [ { "target": "G01260KO", "source": "G86270DU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86270DU", "source": "G11041DA", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01260RY", "notes": [], "error": "No pathways for [G01260RY] could be generated at this time" }, { "glytoucan_ac": "G01265XZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01300OI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76345AA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G76345AA", "dp": 9 }, { "id": "G01300OI", "dp": 9 } ], "links": [ { "target": "G01300OI", "source": "G76345AA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76345AA", "source": "G12398HZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01308XT", "notes": [], "error": "No pathways for [G01308XT] could be generated at this time" }, { "glytoucan_ac": "G01310VF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95542JQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G01310VF", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G01323LL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77384FE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G91337ZP", "dp": 10 }, { "id": "G77384FE", "dp": 11 }, { "id": "G01323LL", "dp": 11 } ], "links": [ { "target": "G01323LL", "source": "G77384FE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77384FE", "source": "G91337ZP", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91337ZP", "source": "G58667NI", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01342FO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G01342FO] could be generated at this time" }, { "glytoucan_ac": "G01354KL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 } ], "links": [ { "target": "G01354KL", "source": "G41611UP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01361CV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11041DA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G01361CV", "dp": 11 } ], "links": [ { "target": "G01361CV", "source": "G11041DA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01375NQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G37022BP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 }, { "id": "G37022BP", "dp": 12 }, { "id": "G01375NQ", "dp": 12 } ], "links": [ { "target": "G01375NQ", "source": "G37022BP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37022BP", "source": "G30460NZ", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01378OV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G71835BN", "dp": 10 } ], "links": [ { "target": "G01378OV", "source": "G71835BN", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G71835BN", "source": "G36191CD", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01406RR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36701GV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G36701GV", "dp": 12 }, { "id": "G01406RR", "dp": 12 } ], "links": [ { "target": "G01406RR", "source": "G36701GV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36701GV", "source": "G53752TA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01414CL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34838RM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G01414CL", "dp": 10 } ], "links": [ { "target": "G01414CL", "source": "G34838RM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01424EN", "notes": [], "error": "No pathways for [G01424EN] could be generated at this time" }, { "glytoucan_ac": "G01450VD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G33001NX", "dp": 8 } ], "links": [ { "target": "G01450VD", "source": "G33001NX", "residue_affected": { "residue_id": "N267", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G33001NX", "source": "G39089YD", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G01476WA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82955EQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G82955EQ", "dp": 11 }, { "id": "G01476WA", "dp": 11 } ], "links": [ { "target": "G01476WA", "source": "G82955EQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82955EQ", "source": "G87073UP", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01489UZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G18219CJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G01489UZ", "dp": 11 } ], "links": [ { "target": "G01489UZ", "source": "G18219CJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01521YU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G01590HD", "notes": [], "error": "No pathways for [G01590HD] could be generated at this time" }, { "glytoucan_ac": "G01613KN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31991IV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G01613KN", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G01669LU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01670UQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91365ZQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G01670UQ", "dp": 10 } ], "links": [ { "target": "G01670UQ", "source": "G91365ZQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01685IB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52187WF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G02290KA", "dp": 10 }, { "id": "G52187WF", "dp": 11 }, { "id": "G01685IB", "dp": 11 } ], "links": [ { "target": "G01685IB", "source": "G52187WF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52187WF", "source": "G02290KA", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G02290KA", "source": "G20030CU", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01727PW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G01727PW] could be generated at this time" }, { "glytoucan_ac": "G01752VH", "notes": [], "error": "No pathways for [G01752VH] could be generated at this time" }, { "glytoucan_ac": "G01789AQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G72662IG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G80537QW", "dp": 14 }, { "id": "G72662IG", "dp": 15 }, { "id": "G01789AQ", "dp": 15 } ], "links": [ { "target": "G01789AQ", "source": "G72662IG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72662IG", "source": "G80537QW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G80537QW", "source": "G93582HM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01856RL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01891JS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G01891JS] could be generated at this time" }, { "glytoucan_ac": "G01923XE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 } ], "links": [ { "target": "G01923XE", "source": "G95898GD", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01935FK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G01935FK", "source": "G36191CD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G01999JH", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G08520NM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G01999JH", "dp": 8 } ], "links": [ { "target": "G01999JH", "source": "G08520NM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G02021XC", "notes": [], "error": "No pathways for [G02021XC] could be generated at this time" }, { "glytoucan_ac": "G02025MF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G02025MF] could be generated at this time" }, { "glytoucan_ac": "G02081QK", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G71972AT]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G02081QK", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G02122FK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40428GO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G02122FK", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G02152MS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36519NW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G36519NW", "dp": 13 }, { "id": "G02152MS", "dp": 13 } ], "links": [ { "target": "G02152MS", "source": "G36519NW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36519NW", "source": "G01669LU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02156UW", "notes": [], "error": "No pathways for [G02156UW] could be generated at this time" }, { "glytoucan_ac": "G02174FQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G94531EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G94531EZ", "dp": 18 }, { "id": "G02174FQ", "dp": 18 } ], "links": [ { "target": "G02174FQ", "source": "G94531EZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02193CV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40194MN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G40194MN", "dp": 16 }, { "id": "G02193CV", "dp": 16 } ], "links": [ { "target": "G02193CV", "source": "G40194MN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40194MN", "source": "G76842ZR", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02207TG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G33241WC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G33241WC", "dp": 15 }, { "id": "G02207TG", "dp": 15 } ], "links": [ { "target": "G02207TG", "source": "G33241WC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33241WC", "source": "G45720CA", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02284UY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G02284UY] could be generated at this time" }, { "glytoucan_ac": "G02290KA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G02290KA", "source": "G20030CU", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02302MM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G75972ZC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G02302MM", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G02310VX", "notes": [], "error": "No pathways for [G02310VX] could be generated at this time" }, { "glytoucan_ac": "G02311IE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 } ], "links": [ { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02322JK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07947TY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G02322JK", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G02410EE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G06209KS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G06209KS", "dp": 8 }, { "id": "G02410EE", "dp": 8 } ], "links": [ { "target": "G02410EE", "source": "G06209KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06209KS", "source": "G69411IG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02422RD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G02422RD", "source": "G10219AA", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02441OB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G03272YQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G21788RU", "dp": 12 }, { "id": "G03272YQ", "dp": 13 }, { "id": "G02441OB", "dp": 13 } ], "links": [ { "target": "G02441OB", "source": "G03272YQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03272YQ", "source": "G21788RU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G21788RU", "source": "G25520XG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02442YU", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G91303GW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G91303GW", "dp": 11 }, { "id": "G02442YU", "dp": 11 } ], "links": [ { "target": "G02442YU", "source": "G91303GW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91303GW", "source": "G45560HM", "residue_affected": { "residue_id": "N216", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02470WS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G02471GW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 } ], "links": [ { "target": "G02471GW", "source": "G32305RZ", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02473HY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G73418FX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G00743WU", "dp": 11 }, { "id": "G73418FX", "dp": 12 }, { "id": "G02473HY", "dp": 12 } ], "links": [ { "target": "G02473HY", "source": "G73418FX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73418FX", "source": "G00743WU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02474FD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G02474FD] could be generated at this time" }, { "glytoucan_ac": "G02483WT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10292TC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G02483WT", "dp": 15 } ], "links": [ { "target": "G02483WT", "source": "G10292TC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02536WY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G02536WY] could be generated at this time" }, { "glytoucan_ac": "G02582JY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G30901GC", "dp": 9 } ], "links": [ { "target": "G02582JY", "source": "G30901GC", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30901GC", "source": "G79348ZY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02646YL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G07392QY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G07392QY", "dp": 11 }, { "id": "G02646YL", "dp": 11 } ], "links": [ { "target": "G02646YL", "source": "G07392QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07392QY", "source": "G78059CC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02654EL", "notes": [], "error": "No pathways for [G02654EL] could be generated at this time" }, { "glytoucan_ac": "G02660WC", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G29492IF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G02660WC", "dp": 8 } ], "links": [ { "target": "G02660WC", "source": "G29492IF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02679YX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G02679YX] could be generated at this time" }, { "glytoucan_ac": "G02760XH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43351VW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G02760XH", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G02786XX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81096RM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G02786XX", "dp": 36 } ], "links": [] } , { "glytoucan_ac": "G02915XR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89941FZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G00743WU", "dp": 11 }, { "id": "G89941FZ", "dp": 12 }, { "id": "G02915XR", "dp": 12 } ], "links": [ { "target": "G02915XR", "source": "G89941FZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89941FZ", "source": "G00743WU", "residue_affected": { "residue_id": "N70", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02934UB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 } ], "links": [ { "target": "G02934UB", "source": "G99074EO", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G02945KQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71470CO]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G71470CO", "dp": 9 }, { "id": "G02945KQ", "dp": 9 } ], "links": [ { "target": "G02945KQ", "source": "G71470CO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71470CO", "source": "G08520NM", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03004PD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13267ZY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G13267ZY", "dp": 10 }, { "id": "G03004PD", "dp": 10 } ], "links": [ { "target": "G03004PD", "source": "G13267ZY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G13267ZY", "source": "G46638GC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03005MJ", "notes": [], "error": "No pathways for [G03005MJ] could be generated at this time" }, { "glytoucan_ac": "G03021WA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G80393PG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G03021WA", "dp": 9 } ], "links": [ { "target": "G03021WA", "source": "G80393PG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03075ZE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 } ], "links": [ { "target": "G03075ZE", "source": "G04989WY", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03136UJ", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G70583LH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G03136UJ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G03164NE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29857PJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G03164NE", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G03165SD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G29377XJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 }, { "id": "G29377XJ", "dp": 12 }, { "id": "G03165SD", "dp": 12 } ], "links": [ { "target": "G03165SD", "source": "G29377XJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29377XJ", "source": "G63585HN", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03177HU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G03203II", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G92024SL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G03203II", "dp": 7 } ], "links": [ { "target": "G03203II", "source": "G92024SL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03207XQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11929SN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G11929SN", "dp": 14 }, { "id": "G03207XQ", "dp": 14 } ], "links": [ { "target": "G03207XQ", "source": "G11929SN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11929SN", "source": "G80294GH", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03216SJ", "notes": [], "error": "No pathways for [G03216SJ] could be generated at this time" }, { "glytoucan_ac": "G03228NK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86083QZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G04185VX", "dp": 10 }, { "id": "G30569KZ", "dp": 11 }, { "id": "G86083QZ", "dp": 12 }, { "id": "G03228NK", "dp": 12 } ], "links": [ { "target": "G03228NK", "source": "G86083QZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86083QZ", "source": "G30569KZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G30569KZ", "source": "G04185VX", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04185VX", "source": "G36191CD", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03230AX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G20711NK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G03230AX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G03250UN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53504BR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G03250UN", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G03260OU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G03260OU] could be generated at this time" }, { "glytoucan_ac": "G03272YQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G21788RU", "dp": 12 } ], "links": [ { "target": "G03272YQ", "source": "G21788RU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G21788RU", "source": "G25520XG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03275SD", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03296OS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G03296OS] could be generated at this time" }, { "glytoucan_ac": "G03321AC", "notes": [], "error": "No pathways for [G03321AC] could be generated at this time" }, { "glytoucan_ac": "G03345AP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G96235XM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G03345AP", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G03346FO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G25505UF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G25505UF", "dp": 14 }, { "id": "G03346FO", "dp": 14 } ], "links": [ { "target": "G03346FO", "source": "G25505UF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03347EL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G78503JC", "dp": 12 }, { "id": "G52886RR", "dp": 13 } ], "links": [ { "target": "G03347EL", "source": "G52886RR", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G52886RR", "source": "G78503JC", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03385XG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 } ], "links": [ { "target": "G03385XG", "source": "G01669LU", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03414KZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40707SF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G03414KZ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G03431NA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G03431NA] could be generated at this time" }, { "glytoucan_ac": "G03445UI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 } ], "links": [ { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03473UD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G03473UD] could be generated at this time" }, { "glytoucan_ac": "G03529DJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82033VN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G82033VN", "dp": 14 }, { "id": "G03529DJ", "dp": 14 } ], "links": [ { "target": "G03529DJ", "source": "G82033VN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82033VN", "source": "G20926BB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03542LT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G03595ET", "notes": [], "error": "No pathways for [G03595ET] could be generated at this time" }, { "glytoucan_ac": "G03600YM", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G45560HM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G03600YM", "dp": 10 } ], "links": [ { "target": "G03600YM", "source": "G45560HM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03605AV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10425AY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G03605AV", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G03605BS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82942ZJ]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G82942ZJ", "dp": 9 }, { "id": "G03605BS", "dp": 9 } ], "links": [ { "target": "G03605BS", "source": "G82942ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82942ZJ", "source": "G08520NM", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03606VC", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G17213JF", "dp": 11 }, { "id": "G56376TA", "dp": 12 } ], "links": [ { "target": "G03606VC", "source": "G56376TA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G56376TA", "source": "G17213JF", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03652TR", "notes": [], "error": "No pathways for [G03652TR] could be generated at this time" }, { "glytoucan_ac": "G03654ML", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41278YY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G82540VC", "dp": 8 }, { "id": "G41278YY", "dp": 9 }, { "id": "G03654ML", "dp": 9 } ], "links": [ { "target": "G03654ML", "source": "G41278YY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41278YY", "source": "G82540VC", "residue_affected": { "residue_id": "N238", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G82540VC", "source": "G39213VZ", "residue_affected": { "residue_id": "N250", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03681UF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39298RF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G71690HK", "dp": 10 }, { "id": "G39298RF", "dp": 11 }, { "id": "G03681UF", "dp": 11 } ], "links": [ { "target": "G03681UF", "source": "G39298RF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39298RF", "source": "G71690HK", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G71690HK", "source": "G61207RZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03727RK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 } ], "links": [ { "target": "G03727RK", "source": "G66282NU", "residue_affected": { "residue_id": "N251", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03740OH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52428MJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G52428MJ", "dp": 10 }, { "id": "G03740OH", "dp": 10 } ], "links": [ { "target": "G03740OH", "source": "G52428MJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52428MJ", "source": "G42672MA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03750RD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65603XA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G80352NL", "dp": 14 }, { "id": "G65603XA", "dp": 15 }, { "id": "G03750RD", "dp": 15 } ], "links": [ { "target": "G03750RD", "source": "G65603XA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65603XA", "source": "G80352NL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G80352NL", "source": "G66282NU", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03754YM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G03754YM] could be generated at this time" }, { "glytoucan_ac": "G03764XL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G22795QB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G03764XL", "dp": 10 } ], "links": [ { "target": "G03764XL", "source": "G22795QB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03783BX", "notes": [], "error": "No pathways for [G03783BX] could be generated at this time" }, { "glytoucan_ac": "G03818JD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G43677TG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G03818JD", "dp": 8 } ], "links": [ { "target": "G03818JD", "source": "G43677TG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03820FM", "notes": [], "error": "No pathways for [G03820FM] could be generated at this time" }, { "glytoucan_ac": "G03834RX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53933HU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G53933HU", "dp": 8 }, { "id": "G03834RX", "dp": 8 } ], "links": [ { "target": "G03834RX", "source": "G53933HU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53933HU", "source": "G59741XZ", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03864MI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G03864MI", "source": "G78059CC", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03895SR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 } ], "links": [ { "target": "G03895SR", "source": "G16150CJ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03921DY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G72221XM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G45187EI", "dp": 11 }, { "id": "G72221XM", "dp": 12 }, { "id": "G03921DY", "dp": 12 } ], "links": [ { "target": "G03921DY", "source": "G72221XM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72221XM", "source": "G45187EI", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G45187EI", "source": "G08577ZR", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03948VT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G03948VT] could be generated at this time" }, { "glytoucan_ac": "G03951JJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 } ], "links": [ { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03962UN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 } ], "links": [ { "target": "G03962UN", "source": "G43677TG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G03974HM", "notes": [], "error": "No pathways for [G03974HM] could be generated at this time" }, { "glytoucan_ac": "G04023GJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54018RP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G04023GJ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G04048YA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59741XZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G04048YA", "dp": 7 } ], "links": [ { "target": "G04048YA", "source": "G59741XZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04065SU", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G04078TP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G04109RU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G62389NM]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G04109RU", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G04163JP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G99954ZJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G20096RP", "dp": 12 }, { "id": "G99954ZJ", "dp": 13 }, { "id": "G04163JP", "dp": 13 } ], "links": [ { "target": "G04163JP", "source": "G99954ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99954ZJ", "source": "G20096RP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20096RP", "source": "G25520XG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04185VX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G04185VX", "source": "G36191CD", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04213EK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 } ], "links": [ { "target": "G04213EK", "source": "G79609RF", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04214MY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 } ], "links": [ { "target": "G04214MY", "source": "G28826SH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04216GB", "notes": [], "error": "No pathways for [G04216GB] could be generated at this time" }, { "glytoucan_ac": "G04220HB", "notes": [], "error": "No pathways for [G04220HB] could be generated at this time" }, { "glytoucan_ac": "G04246XX", "notes": [], "error": "No pathways for [G04246XX] could be generated at this time" }, { "glytoucan_ac": "G04261UG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G04269TC", "notes": [], "error": "No pathways for [G04269TC] could be generated at this time" }, { "glytoucan_ac": "G04273XP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G03385XG", "dp": 13 } ], "links": [ { "target": "G04273XP", "source": "G03385XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G03385XG", "source": "G01669LU", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04414GO", "notes": [], "error": "No pathways for [G04414GO] could be generated at this time" }, { "glytoucan_ac": "G04423CA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61203OK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G04423CA", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G04445KN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53168IY]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [G53168IY] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G04448SF", "notes": [], "error": "No pathways for [G04448SF] could be generated at this time" }, { "glytoucan_ac": "G04467BX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G06283RQ", "dp": 12 } ], "links": [ { "target": "G04467BX", "source": "G06283RQ", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G06283RQ", "source": "G31010RQ", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04471LY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 } ], "links": [ { "target": "G04471LY", "source": "G79609RF", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04483SK", "notes": [], "error": "No pathways for [G04483SK] could be generated at this time" }, { "glytoucan_ac": "G04508HC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G00176HZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G04508HC", "dp": 10 } ], "links": [ { "target": "G04508HC", "source": "G00176HZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04544OS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 } ], "links": [ { "target": "G04544OS", "source": "G12740VA", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04554UL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G04554UL", "source": "G91365ZQ", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04562GJ", "notes": [], "error": "No pathways for [G04562GJ] could be generated at this time" }, { "glytoucan_ac": "G04576KS", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G04576KS", "source": "G16828VN", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04598XU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G19687OL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G04598XU", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G04622LK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38115KZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G71857KQ", "dp": 10 }, { "id": "G38115KZ", "dp": 11 }, { "id": "G04622LK", "dp": 11 } ], "links": [ { "target": "G04622LK", "source": "G38115KZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38115KZ", "source": "G71857KQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71857KQ", "source": "G29434RB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04681PT", "notes": [], "error": "No pathways for [G04681PT] could be generated at this time" }, { "glytoucan_ac": "G04708ME", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G72536JI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 }, { "id": "G72536JI", "dp": 13 }, { "id": "G04708ME", "dp": 13 } ], "links": [ { "target": "G04708ME", "source": "G72536JI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72536JI", "source": "G81432SH", "residue_affected": { "residue_id": "N237", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04717US", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G02290KA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G02290KA", "dp": 10 }, { "id": "G04717US", "dp": 10 } ], "links": [ { "target": "G04717US", "source": "G02290KA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02290KA", "source": "G20030CU", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04719BG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81326IN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G04719BG", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G04743RS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 } ], "links": [ { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04744XB", "notes": [], "error": "No pathways for [G04744XB] could be generated at this time" }, { "glytoucan_ac": "G04751OE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81085EP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G81085EP", "dp": 11 }, { "id": "G04751OE", "dp": 11 } ], "links": [ { "target": "G04751OE", "source": "G81085EP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G81085EP", "source": "G87073UP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04751SB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G04764ON", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 } ], "links": [ { "target": "G04764ON", "source": "G30302VM", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04767HS", "notes": [], "error": "No pathways for [G04767HS] could be generated at this time" }, { "glytoucan_ac": "G04775TV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G15828WB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G88382QE", "dp": 14 }, { "id": "G15828WB", "dp": 15 }, { "id": "G04775TV", "dp": 15 } ], "links": [ { "target": "G04775TV", "source": "G15828WB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G15828WB", "source": "G88382QE", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G88382QE", "source": "G18938DW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04783EJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G04783EJ] could be generated at this time" }, { "glytoucan_ac": "G04791QM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04791YX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G04791YX] could be generated at this time" }, { "glytoucan_ac": "G04792UK", "notes": [], "error": "No pathways for [G04792UK] could be generated at this time" }, { "glytoucan_ac": "G04816EV", "notes": [], "error": "No pathways for [G04816EV] could be generated at this time" }, { "glytoucan_ac": "G04820ZT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32305RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G04820ZT", "dp": 10 } ], "links": [ { "target": "G04820ZT", "source": "G32305RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04829RO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 }, { "id": "G01010HW", "dp": 9 } ], "links": [ { "target": "G04829RO", "source": "G01010HW", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04855ZO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G37597FW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 }, { "id": "G04855ZO", "dp": 13 } ], "links": [ { "target": "G04855ZO", "source": "G37597FW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04903PZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G71704AG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G42686NQ", "dp": 14 }, { "id": "G71704AG", "dp": 15 }, { "id": "G04903PZ", "dp": 15 } ], "links": [ { "target": "G04903PZ", "source": "G71704AG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71704AG", "source": "G42686NQ", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G42686NQ", "source": "G19726AG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04964UA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60667OL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G11535IB", "dp": 9 }, { "id": "G60667OL", "dp": 10 }, { "id": "G04964UA", "dp": 10 } ], "links": [ { "target": "G04964UA", "source": "G60667OL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60667OL", "source": "G11535IB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11535IB", "source": "G59471TH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G04987NY", "notes": [], "error": "No pathways for [G04987NY] could be generated at this time" }, { "glytoucan_ac": "G04989WY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 } ], "links": [ { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05060ST", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G05060ST] could be generated at this time" }, { "glytoucan_ac": "G05096LE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G59989VG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G05096LE", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G05120VZ", "notes": [], "error": "No pathways for [G05120VZ] could be generated at this time" }, { "glytoucan_ac": "G05143WC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 }, { "id": "G97958KV", "dp": 11 } ], "links": [ { "target": "G05143WC", "source": "G97958KV", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G97958KV", "source": "G06969ZX", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05151WT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 } ], "links": [ { "target": "G05151WT", "source": "G59877NF", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05188BU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58547FH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G05188BU", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G05253EZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G05260RH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 } ], "links": [ { "target": "G05260RH", "source": "G56591LC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05303BZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 } ], "links": [ { "target": "G05303BZ", "source": "G28826SH", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05307LM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 } ], "links": [ { "target": "G05307LM", "source": "G91023GB", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05319BS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G48954CA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G48954CA", "dp": 9 }, { "id": "G05319BS", "dp": 9 } ], "links": [ { "target": "G05319BS", "source": "G48954CA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G48954CA", "source": "G12398HZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05360PA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G40554DX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G40554DX", "dp": 14 }, { "id": "G05360PA", "dp": 14 } ], "links": [ { "target": "G05360PA", "source": "G40554DX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40554DX", "source": "G75120WS", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05368PM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 } ], "links": [ { "target": "G05368PM", "source": "G89993FE", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05382JE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G61207RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G05382JE", "dp": 9 } ], "links": [ { "target": "G05382JE", "source": "G61207RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05421OW", "notes": [], "error": "No pathways for [G05421OW] could be generated at this time" }, { "glytoucan_ac": "G05441GN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G93698KA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G05441GN", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G05478GN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82320NZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G05478GN", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G05546WG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 } ], "links": [ { "target": "G05546WG", "source": "G69812OF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05552HC", "notes": [], "error": "No pathways for [G05552HC] could be generated at this time" }, { "glytoucan_ac": "G05561HT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G79099UV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G05561HT", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G05562XX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G05562XX] could be generated at this time" }, { "glytoucan_ac": "G05600OX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G05600OX] could be generated at this time" }, { "glytoucan_ac": "G05611SB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59877NF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G05611SB", "dp": 11 } ], "links": [ { "target": "G05611SB", "source": "G59877NF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05619KO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G84852GW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G84852GW", "dp": 9 }, { "id": "G05619KO", "dp": 9 } ], "links": [ { "target": "G05619KO", "source": "G84852GW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84852GW", "source": "G12398HZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05654CV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G73977KO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G05654CV", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G05698FC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G80661IW", "dp": 10 }, { "id": "G85319UV", "dp": 11 } ], "links": [ { "target": "G05698FC", "source": "G85319UV", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G85319UV", "source": "G80661IW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G80661IW", "source": "G46638GC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05763EW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G13151XE]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 }, { "id": "G05763EW", "dp": 9 } ], "links": [ { "target": "G05763EW", "source": "G13151XE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05794RZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G40806JH", "dp": 11 } ], "links": [ { "target": "G05794RZ", "source": "G40806JH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05801RW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 } ], "links": [ { "target": "G05801RW", "source": "G99645NK", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05808PZ", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G03275SD", "dp": 10 } ], "links": [ { "target": "G05808PZ", "source": "G03275SD", "residue_affected": { "residue_id": "N476", "pubchem_name": "phosphate", "anomer": "n", "absolute": "n", "form_name": "phosphate", "full_name": "-n-phosphate" }, "effect": "Adds -n-phosphate", "enzymes": [] }, { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05840XL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G72821WX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G72821WX", "dp": 9 }, { "id": "G05840XL", "dp": 9 } ], "links": [ { "target": "G05840XL", "source": "G72821WX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72821WX", "source": "G12398HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G05892GB", "notes": [], "error": "No pathways for [G05892GB] could be generated at this time" }, { "glytoucan_ac": "G05948HK", "notes": [], "error": "No pathways for [G05948HK] could be generated at this time" }, { "glytoucan_ac": "G05979RR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60103QI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G54611ZT", "dp": 11 }, { "id": "G60103QI", "dp": 12 }, { "id": "G05979RR", "dp": 12 } ], "links": [ { "target": "G05979RR", "source": "G60103QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60103QI", "source": "G54611ZT", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06017WG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59128IS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 }, { "id": "G56147VV", "dp": 15 }, { "id": "G59128IS", "dp": 16 }, { "id": "G06017WG", "dp": 16 } ], "links": [ { "target": "G06017WG", "source": "G59128IS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59128IS", "source": "G56147VV", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G56147VV", "source": "G17168RO", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06022SA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G05600OX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G06022SA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G06032HI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G29112GC", "dp": 10 }, { "id": "G72060AW", "dp": 11 } ], "links": [ { "target": "G06032HI", "source": "G72060AW", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G72060AW", "source": "G29112GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29112GC", "source": "G20030CU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06059DJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G16774YZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 }, { "id": "G16774YZ", "dp": 18 }, { "id": "G06059DJ", "dp": 18 } ], "links": [ { "target": "G06059DJ", "source": "G16774YZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16774YZ", "source": "G86696LV", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06067KZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G64633BH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G64633BH", "dp": 9 }, { "id": "G06067KZ", "dp": 9 } ], "links": [ { "target": "G06067KZ", "source": "G64633BH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G64633BH", "source": "G79348ZY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06070KG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G20956ZK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G06070KG", "dp": 8 } ], "links": [ { "target": "G06070KG", "source": "G20956ZK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06131VP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 } ], "links": [ { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06142UM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93193OD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 }, { "id": "G17473NR", "dp": 13 }, { "id": "G93193OD", "dp": 14 }, { "id": "G06142UM", "dp": 14 } ], "links": [ { "target": "G06142UM", "source": "G93193OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93193OD", "source": "G17473NR", "residue_affected": { "residue_id": "N267", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G17473NR", "source": "G10733HY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06152YZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 } ], "links": [ { "target": "G06152YZ", "source": "G89993FE", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06162IF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G06191GU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 } ], "links": [ { "target": "G06191GU", "source": "G79809MM", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06195HM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G04214MY", "dp": 11 } ], "links": [ { "target": "G06195HM", "source": "G04214MY", "residue_affected": { "residue_id": "N237", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04214MY", "source": "G28826SH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06209KS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G06209KS", "source": "G69411IG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06215DG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46712PI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G46712PI", "dp": 11 }, { "id": "G06215DG", "dp": 11 } ], "links": [ { "target": "G06215DG", "source": "G46712PI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46712PI", "source": "G00176HZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06216UH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 } ], "links": [ { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06279KD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10691MJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G06279KD", "dp": 11 } ], "links": [ { "target": "G06279KD", "source": "G10691MJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06283RQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 } ], "links": [ { "target": "G06283RQ", "source": "G31010RQ", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06290ZS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G32611KT", "dp": 8 } ], "links": [ { "target": "G06290ZS", "source": "G32611KT", "residue_affected": { "residue_id": "N32", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32611KT", "source": "G39213VZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06301TU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G52428MJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G52428MJ", "dp": 10 }, { "id": "G06301TU", "dp": 10 } ], "links": [ { "target": "G06301TU", "source": "G52428MJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52428MJ", "source": "G42672MA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06371NP", "notes": [], "error": "No pathways for [G06371NP] could be generated at this time" }, { "glytoucan_ac": "G06374YY", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G06374YY", "source": "G16828VN", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06400QJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39377DE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G39377DE", "dp": 11 }, { "id": "G06400QJ", "dp": 11 } ], "links": [ { "target": "G06400QJ", "source": "G39377DE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39377DE", "source": "G09921WG", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06404ZJ", "notes": [], "error": "No pathways for [G06404ZJ] could be generated at this time" }, { "glytoucan_ac": "G06432WK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G06437BU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21050RT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G06437BU", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G06444RU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G66847YI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G06444RU", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G06550JR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G89993FE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G06550JR", "dp": 8 } ], "links": [ { "target": "G06550JR", "source": "G89993FE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06578MY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G20170YB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 }, { "id": "G20170YB", "dp": 12 }, { "id": "G06578MY", "dp": 12 } ], "links": [ { "target": "G06578MY", "source": "G20170YB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20170YB", "source": "G63585HN", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06581HO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 } ], "links": [ { "target": "G06581HO", "source": "G71679MX", "residue_affected": { "residue_id": "N59", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06586DL", "notes": [], "error": "No pathways for [G06586DL] could be generated at this time" }, { "glytoucan_ac": "G06594DV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G06594DV] could be generated at this time" }, { "glytoucan_ac": "G06607JJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G16155TD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G16155TD", "dp": 13 }, { "id": "G06607JJ", "dp": 13 } ], "links": [ { "target": "G06607JJ", "source": "G16155TD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16155TD", "source": "G01669LU", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06635WE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G06635WE] could be generated at this time" }, { "glytoucan_ac": "G06648CG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 } ], "links": [ { "target": "G06648CG", "source": "G06969ZX", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06721LM", "notes": [], "error": "No pathways for [G06721LM] could be generated at this time" }, { "glytoucan_ac": "G06729UK", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 } ], "links": [ { "target": "G06729UK", "source": "G13151XE", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06730AH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82779CI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G06730AH", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G06731AE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54505OS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 }, { "id": "G54505OS", "dp": 11 }, { "id": "G06731AE", "dp": 11 } ], "links": [ { "target": "G06731AE", "source": "G54505OS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G54505OS", "source": "G65597BI", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06768XI", "notes": [], "error": "No pathways for [G06768XI] could be generated at this time" }, { "glytoucan_ac": "G06772YH", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 } ], "links": [ { "target": "G06772YH", "source": "G20966TZ", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06795XH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 } ], "links": [ { "target": "G06795XH", "source": "G03445UI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06804FL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25406HP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G06804FL", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G06820QR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 } ], "links": [ { "target": "G06820QR", "source": "G53485VW", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06830II", "notes": [], "error": "No pathways for [G06830II] could be generated at this time" }, { "glytoucan_ac": "G06833NJ", "notes": [], "error": "No pathways for [G06833NJ] could be generated at this time" }, { "glytoucan_ac": "G06885ZB", "notes": [], "error": "No pathways for [G06885ZB] could be generated at this time" }, { "glytoucan_ac": "G06906MP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G06906MP] could be generated at this time" }, { "glytoucan_ac": "G06920GM", "notes": [], "error": "No pathways for [G06920GM] could be generated at this time" }, { "glytoucan_ac": "G06968OS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G20018DL", "dp": 14 } ], "links": [ { "target": "G06968OS", "source": "G20018DL", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G20018DL", "source": "G18938DW", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G06969ZX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07014AW", "notes": [], "error": "No pathways for [G07014AW] could be generated at this time" }, { "glytoucan_ac": "G07015TW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G10664FL", "dp": 10 } ], "links": [ { "target": "G07015TW", "source": "G10664FL", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10664FL", "source": "G45262QY", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07041CT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G97765TT", "dp": 12 } ], "links": [ { "target": "G07041CT", "source": "G97765TT", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G97765TT", "source": "G18219CJ", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07098TP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43507KQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G09826WW", "dp": 11 }, { "id": "G43507KQ", "dp": 12 }, { "id": "G07098TP", "dp": 12 } ], "links": [ { "target": "G07098TP", "source": "G43507KQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43507KQ", "source": "G09826WW", "residue_affected": { "residue_id": "N272", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G09826WW", "source": "G85542KD", "residue_affected": { "residue_id": "N271", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07141SK", "notes": [], "error": "No pathways for [G07141SK] could be generated at this time" }, { "glytoucan_ac": "G07147QM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30901GC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G30901GC", "dp": 9 }, { "id": "G07147QM", "dp": 9 } ], "links": [ { "target": "G07147QM", "source": "G30901GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30901GC", "source": "G79348ZY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07162IJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G07162IJ] could be generated at this time" }, { "glytoucan_ac": "G07169PS", "notes": [], "error": "No pathways for [G07169PS] could be generated at this time" }, { "glytoucan_ac": "G07209HW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G92024SL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G07209HW", "dp": 7 } ], "links": [ { "target": "G07209HW", "source": "G92024SL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07218NO", "notes": [], "error": "No pathways for [G07218NO] could be generated at this time" }, { "glytoucan_ac": "G07228BR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 } ], "links": [ { "target": "G07228BR", "source": "G93500PH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07233JN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G07248LS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 }, { "id": "G36268TW", "dp": 12 } ], "links": [ { "target": "G07248LS", "source": "G36268TW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G36268TW", "source": "G77252PU", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07262RR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G07262RR] could be generated at this time" }, { "glytoucan_ac": "G07292LK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60963AS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 }, { "id": "G65796FM", "dp": 13 }, { "id": "G60963AS", "dp": 14 }, { "id": "G07292LK", "dp": 14 } ], "links": [ { "target": "G07292LK", "source": "G60963AS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60963AS", "source": "G65796FM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G65796FM", "source": "G79344MI", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07322RE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60926LS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G71690HK", "dp": 10 }, { "id": "G39298RF", "dp": 11 }, { "id": "G60926LS", "dp": 12 }, { "id": "G07322RE", "dp": 12 } ], "links": [ { "target": "G07322RE", "source": "G60926LS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60926LS", "source": "G39298RF", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39298RF", "source": "G71690HK", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G71690HK", "source": "G61207RZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07328EF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74120DW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G07328EF", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G07337US", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G13156PQ", "dp": 12 } ], "links": [ { "target": "G07337US", "source": "G13156PQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G13156PQ", "source": "G53752TA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07352BK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G83402YY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G07352BK", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G07368IA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G33802UM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G07368IA", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G07376BS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G75120WS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G07376BS", "dp": 13 } ], "links": [ { "target": "G07376BS", "source": "G75120WS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07380TS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99270AV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 }, { "id": "G07380TS", "dp": 10 } ], "links": [ { "target": "G07380TS", "source": "G99270AV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07392QY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G07392QY", "source": "G78059CC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07410AW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 } ], "links": [ { "target": "G07410AW", "source": "G37597FW", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07483YN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07505DF", "notes": [], "error": "No pathways for [G07505DF] could be generated at this time" }, { "glytoucan_ac": "G07528DS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G55314RK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G07528DS", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G07568IR", "notes": [], "error": "No pathways for [G07568IR] could be generated at this time" }, { "glytoucan_ac": "G07589QZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G18026EK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G18026EK", "dp": 12 }, { "id": "G07589QZ", "dp": 12 } ], "links": [ { "target": "G07589QZ", "source": "G18026EK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18026EK", "source": "G37046CZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07617FP", "notes": [], "error": "No pathways for [G07617FP] could be generated at this time" }, { "glytoucan_ac": "G07626WD", "notes": [], "error": "No pathways for [G07626WD] could be generated at this time" }, { "glytoucan_ac": "G07640EG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 }, { "id": "G01010HW", "dp": 9 }, { "id": "G11588II", "dp": 10 }, { "id": "G61312PU", "dp": 11 } ], "links": [ { "target": "G07640EG", "source": "G61312PU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61312PU", "source": "G11588II", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G11588II", "source": "G01010HW", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07666IB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82861UH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G82861UH", "dp": 9 }, { "id": "G07666IB", "dp": 9 } ], "links": [ { "target": "G07666IB", "source": "G82861UH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82861UH", "source": "G59471TH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07669FN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G06131VP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G07669FN", "dp": 11 } ], "links": [ { "target": "G07669FN", "source": "G06131VP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07674LF", "notes": [], "error": "No pathways for [G07674LF] could be generated at this time" }, { "glytoucan_ac": "G07695ZT", "notes": [], "error": "No pathways for [G07695ZT] could be generated at this time" }, { "glytoucan_ac": "G07699XI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 } ], "links": [ { "target": "G07699XI", "source": "G78155FK", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07703ST", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34819LS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G07703ST", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G07800ED", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G40358EZ", "dp": 11 } ], "links": [ { "target": "G07800ED", "source": "G40358EZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G40358EZ", "source": "G00176HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07802IC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 } ], "links": [ { "target": "G07802IC", "source": "G56749GV", "residue_affected": { "residue_id": "N483", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07810DU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G07815PK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G07817HH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10425AY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G07817HH", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G07829JQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88468EP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G29706UC", "dp": 10 }, { "id": "G88468EP", "dp": 11 }, { "id": "G07829JQ", "dp": 11 } ], "links": [ { "target": "G07829JQ", "source": "G88468EP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88468EP", "source": "G29706UC", "residue_affected": { "residue_id": "N484", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G29706UC", "source": "G58667NI", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07842DQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14393TF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G07842DQ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G07865ET", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G07887XY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17213JF]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G17213JF", "dp": 11 }, { "id": "G07887XY", "dp": 11 } ], "links": [ { "target": "G07887XY", "source": "G17213JF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07920ZX", "notes": [], "error": "No pathways for [G07920ZX] could be generated at this time" }, { "glytoucan_ac": "G07947TY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G07947TY] could be generated at this time" }, { "glytoucan_ac": "G07982BU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G34838RM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G07982BU", "dp": 10 } ], "links": [ { "target": "G07982BU", "source": "G34838RM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07990UY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G75850OP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G75850OP", "dp": 10 }, { "id": "G07990UY", "dp": 10 } ], "links": [ { "target": "G07990UY", "source": "G75850OP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75850OP", "source": "G36191CD", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G07995VK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08005PG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G84536BM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G08005PG", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G08060JF", "notes": [], "error": "No pathways for [G08060JF] could be generated at this time" }, { "glytoucan_ac": "G08062CY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G08062CY] could be generated at this time" }, { "glytoucan_ac": "G08076GP", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G08076GP] could be generated at this time" }, { "glytoucan_ac": "G08078RH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77485UZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G08078RH", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G08096ND", "notes": [], "error": "No pathways for [G08096ND] could be generated at this time" }, { "glytoucan_ac": "G08111FJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G22558JP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G08111FJ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G08113XU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23824AT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 }, { "id": "G23824AT", "dp": 11 }, { "id": "G08113XU", "dp": 11 } ], "links": [ { "target": "G08113XU", "source": "G23824AT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23824AT", "source": "G56591LC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08161JQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08577ZR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G08161JQ", "dp": 10 } ], "links": [ { "target": "G08161JQ", "source": "G08577ZR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08187GM", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08191RW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99954ZJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G20096RP", "dp": 12 }, { "id": "G99954ZJ", "dp": 13 }, { "id": "G08191RW", "dp": 13 } ], "links": [ { "target": "G08191RW", "source": "G99954ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99954ZJ", "source": "G20096RP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20096RP", "source": "G25520XG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08194HH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08205LJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 } ], "links": [ { "target": "G08205LJ", "source": "G48658PB", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08242BT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 } ], "links": [ { "target": "G08242BT", "source": "G26949IX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08340FW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 } ], "links": [ { "target": "G08340FW", "source": "G39089YD", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G08364MT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25505UF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G25505UF", "dp": 14 }, { "id": "G08364MT", "dp": 14 } ], "links": [ { "target": "G08364MT", "source": "G25505UF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08371QU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G69086TY", "dp": 12 }, { "id": "G42400JK", "dp": 13 } ], "links": [ { "target": "G08371QU", "source": "G42400JK", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G42400JK", "source": "G69086TY", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08418PB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08863NS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G08418PB", "dp": 10 } ], "links": [ { "target": "G08418PB", "source": "G08863NS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08450OR", "notes": [], "error": "No pathways for [G08450OR] could be generated at this time" }, { "glytoucan_ac": "G08456TO", "notes": [], "error": "No pathways for [G08456TO] could be generated at this time" }, { "glytoucan_ac": "G08474XG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G87073UP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G08474XG", "dp": 10 } ], "links": [ { "target": "G08474XG", "source": "G87073UP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08492JZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G65796FM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 }, { "id": "G65796FM", "dp": 13 }, { "id": "G08492JZ", "dp": 13 } ], "links": [ { "target": "G08492JZ", "source": "G65796FM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65796FM", "source": "G79344MI", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08493GY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G08493GY] could be generated at this time" }, { "glytoucan_ac": "G08520NM", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G08520NM] could be generated at this time" }, { "glytoucan_ac": "G08551YA", "notes": [], "error": "No pathways for [G08551YA] could be generated at this time" }, { "glytoucan_ac": "G08561XZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G13585JF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G08561XZ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G08577ZR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 } ], "links": [ { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08646IB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53728DU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G53728DU", "dp": 11 }, { "id": "G08646IB", "dp": 11 } ], "links": [ { "target": "G08646IB", "source": "G53728DU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53728DU", "source": "G91365ZQ", "residue_affected": { "residue_id": "N276", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08646YJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G75850OP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G75850OP", "dp": 10 }, { "id": "G08646YJ", "dp": 10 } ], "links": [ { "target": "G08646YJ", "source": "G75850OP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75850OP", "source": "G36191CD", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08675PK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53288JQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G08675PK", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G08679EM", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G81432SH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 }, { "id": "G08679EM", "dp": 12 } ], "links": [ { "target": "G08679EM", "source": "G81432SH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08679LR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G94394GK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G08679LR", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G08709JB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 } ], "links": [ { "target": "G08709JB", "source": "G45359RY", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08755WX", "notes": [], "error": "No pathways for [G08755WX] could be generated at this time" }, { "glytoucan_ac": "G08820NR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G44946WH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G08820NR", "dp": 10 } ], "links": [ { "target": "G08820NR", "source": "G44946WH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08826KQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11012KS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G11012KS", "dp": 12 }, { "id": "G08826KQ", "dp": 12 } ], "links": [ { "target": "G08826KQ", "source": "G11012KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11012KS", "source": "G37046CZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08863NS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08866CW", "notes": [], "error": "No pathways for [G08866CW] could be generated at this time" }, { "glytoucan_ac": "G08882LF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G39018CC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G25505UF", "dp": 14 }, { "id": "G39018CC", "dp": 15 }, { "id": "G08882LF", "dp": 15 } ], "links": [ { "target": "G08882LF", "source": "G39018CC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39018CC", "source": "G25505UF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08894MB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G45262QY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G08894MB", "dp": 9 } ], "links": [ { "target": "G08894MB", "source": "G45262QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08896RO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G08896RO] could be generated at this time" }, { "glytoucan_ac": "G08907YK", "notes": [], "error": "No pathways for [G08907YK] could be generated at this time" }, { "glytoucan_ac": "G08936DJ", "notes": [], "error": "No pathways for [G08936DJ] could be generated at this time" }, { "glytoucan_ac": "G08949VK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G90564EX", "dp": 11 } ], "links": [ { "target": "G08949VK", "source": "G90564EX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90564EX", "source": "G28826SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G08997GC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G08997GC] could be generated at this time" }, { "glytoucan_ac": "G09019KT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G60941RE", "dp": 13 } ], "links": [ { "target": "G09019KT", "source": "G60941RE", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60941RE", "source": "G75185NU", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09020HN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75398ZA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G09020HN", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G09025ID", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69960SA]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G09025ID", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G09057LN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G66665YI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G66665YI", "dp": 14 }, { "id": "G09057LN", "dp": 14 } ], "links": [ { "target": "G09057LN", "source": "G66665YI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66665YI", "source": "G66282NU", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09064IP", "notes": [], "error": "No pathways for [G09064IP] could be generated at this time" }, { "glytoucan_ac": "G09066KJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G09066KJ] could be generated at this time" }, { "glytoucan_ac": "G09115OQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82234NO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G09115OQ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G09118YK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 }, { "id": "G03895SR", "dp": 15 } ], "links": [ { "target": "G09118YK", "source": "G03895SR", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G03895SR", "source": "G16150CJ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09125WG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07262RR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G09125WG", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G09130LO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07228BR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G07228BR", "dp": 10 }, { "id": "G09130LO", "dp": 10 } ], "links": [ { "target": "G09130LO", "source": "G07228BR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07228BR", "source": "G93500PH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09150LP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 } ], "links": [ { "target": "G09150LP", "source": "G88948CY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09255AF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G09260EL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59579TL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G86753CK", "dp": 17 }, { "id": "G59579TL", "dp": 18 }, { "id": "G09260EL", "dp": 18 } ], "links": [ { "target": "G09260EL", "source": "G59579TL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59579TL", "source": "G86753CK", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86753CK", "source": "G02311IE", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09276TA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G11034PZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G09276TA", "dp": 12 } ], "links": [ { "target": "G09276TA", "source": "G11034PZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09322OS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84376FR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G09322OS", "dp": 12 } ], "links": [ { "target": "G09322OS", "source": "G84376FR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09349XQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79099UV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G09349XQ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G09351VH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G71679MX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G09351VH", "dp": 11 } ], "links": [ { "target": "G09351VH", "source": "G71679MX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09362PR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G61751GZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G09362PR", "dp": 6 } ], "links": [ { "target": "G09362PR", "source": "G61751GZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G09362VG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G87457SB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G09362VG", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G09389FE", "notes": [], "error": "No pathways for [G09389FE] could be generated at this time" }, { "glytoucan_ac": "G09393NL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G15828WB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G88382QE", "dp": 14 }, { "id": "G15828WB", "dp": 15 }, { "id": "G09393NL", "dp": 15 } ], "links": [ { "target": "G09393NL", "source": "G15828WB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G15828WB", "source": "G88382QE", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G88382QE", "source": "G18938DW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09416DG", "notes": [], "error": "No pathways for [G09416DG] could be generated at this time" }, { "glytoucan_ac": "G09420NN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52770HR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G52770HR", "dp": 10 }, { "id": "G09420NN", "dp": 10 } ], "links": [ { "target": "G09420NN", "source": "G52770HR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52770HR", "source": "G36191CD", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09446VC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 } ], "links": [ { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09452ED", "notes": [], "error": "No pathways for [G09452ED] could be generated at this time" }, { "glytoucan_ac": "G09482NW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 } ], "links": [ { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09513RD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G74438AB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 }, { "id": "G74438AB", "dp": 12 }, { "id": "G09513RD", "dp": 12 } ], "links": [ { "target": "G09513RD", "source": "G74438AB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74438AB", "source": "G34905OT", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09538AR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G09556KR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G09556KR] could be generated at this time" }, { "glytoucan_ac": "G09568JT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G18938DW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G09568JT", "dp": 13 } ], "links": [ { "target": "G09568JT", "source": "G18938DW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09576QH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G09576QH] could be generated at this time" }, { "glytoucan_ac": "G09578TK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61088TM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G61088TM", "dp": 12 }, { "id": "G09578TK", "dp": 12 } ], "links": [ { "target": "G09578TK", "source": "G61088TM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61088TM", "source": "G90870DG", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09605DV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G09629PQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 }, { "id": "G04544OS", "dp": 11 }, { "id": "G95201NS", "dp": 12 } ], "links": [ { "target": "G09629PQ", "source": "G95201NS", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95201NS", "source": "G04544OS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04544OS", "source": "G12740VA", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09650BK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38753OV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G38753OV", "dp": 11 }, { "id": "G09650BK", "dp": 11 } ], "links": [ { "target": "G09650BK", "source": "G38753OV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38753OV", "source": "G52934AK", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09666WO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09446VC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 }, { "id": "G09666WO", "dp": 10 } ], "links": [ { "target": "G09666WO", "source": "G09446VC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09670SR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 } ], "links": [ { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09675DY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G84467IZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 }, { "id": "G09675DY", "dp": 11 } ], "links": [ { "target": "G09675DY", "source": "G84467IZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09696LZ", "notes": [], "error": "No pathways for [G09696LZ] could be generated at this time" }, { "glytoucan_ac": "G09724ZC", "notes": [], "error": "No pathways for [G09724ZC] could be generated at this time" }, { "glytoucan_ac": "G09727XA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28723UT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G28723UT", "dp": 11 }, { "id": "G09727XA", "dp": 11 } ], "links": [ { "target": "G09727XA", "source": "G28723UT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28723UT", "source": "G87073UP", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09730EH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G09782JM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 } ], "links": [ { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09826WW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 } ], "links": [ { "target": "G09826WW", "source": "G85542KD", "residue_affected": { "residue_id": "N271", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09857WN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G70684QL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G09857WN", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G09902CG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G75308SV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G88966ZO", "dp": 15 }, { "id": "G75308SV", "dp": 16 }, { "id": "G09902CG", "dp": 16 } ], "links": [ { "target": "G09902CG", "source": "G75308SV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75308SV", "source": "G88966ZO", "residue_affected": { "residue_id": "N37", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88966ZO", "source": "G63889NK", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09909FT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G80085KS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G09909FT", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G09921WG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 } ], "links": [ { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G09947VE", "notes": [], "error": "No pathways for [G09947VE] could be generated at this time" }, { "glytoucan_ac": "G09976WS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 } ], "links": [ { "target": "G09976WS", "source": "G92024SL", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10026RE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G47011KD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G47011KD", "dp": 9 }, { "id": "G10026RE", "dp": 9 } ], "links": [ { "target": "G10026RE", "source": "G47011KD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47011KD", "source": "G34527RW", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10034LM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 } ], "links": [ { "target": "G10034LM", "source": "G90284FM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10040DS", "notes": [], "error": "No pathways for [G10040DS] could be generated at this time" }, { "glytoucan_ac": "G10106TL", "notes": [], "error": "No pathways for [G10106TL] could be generated at this time" }, { "glytoucan_ac": "G10108GZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G44005DK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10108GZ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G10179FS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G36191CD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G10179FS", "dp": 9 } ], "links": [ { "target": "G10179FS", "source": "G36191CD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10182XZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10189EJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82036CW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10189EJ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G10197JO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G79348ZY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G10197JO", "dp": 8 } ], "links": [ { "target": "G10197JO", "source": "G79348ZY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10209QU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10219AA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10223RO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G90175OT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G37476QB", "dp": 8 }, { "id": "G90175OT", "dp": 9 }, { "id": "G10223RO", "dp": 9 } ], "links": [ { "target": "G10223RO", "source": "G90175OT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90175OT", "source": "G37476QB", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G37476QB", "source": "G59741XZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10228AY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G35565NM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 }, { "id": "G35565NM", "dp": 15 }, { "id": "G10228AY", "dp": 15 } ], "links": [ { "target": "G10228AY", "source": "G35565NM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G35565NM", "source": "G53485VW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10228OD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 } ], "links": [ { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10236SD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G97674NY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G97674NY", "dp": 15 }, { "id": "G10236SD", "dp": 15 } ], "links": [ { "target": "G10236SD", "source": "G97674NY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G97674NY", "source": "G89877QI", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10240SH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G10255XW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G16759KR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G10255XW", "dp": 9 } ], "links": [ { "target": "G10255XW", "source": "G16759KR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10258MC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G25835MT", "dp": 10 } ], "links": [ { "target": "G10258MC", "source": "G25835MT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10270EI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G73057DA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G73057DA", "dp": 9 }, { "id": "G10270EI", "dp": 9 } ], "links": [ { "target": "G10270EI", "source": "G73057DA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73057DA", "source": "G34527RW", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10292TC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 } ], "links": [ { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10295MW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G10295MW] could be generated at this time" }, { "glytoucan_ac": "G10300DY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G10300DY] could be generated at this time" }, { "glytoucan_ac": "G10382VG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G49515VE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 }, { "id": "G10382VG", "dp": 12 } ], "links": [ { "target": "G10382VG", "source": "G49515VE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10385EY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G10385EY] could be generated at this time" }, { "glytoucan_ac": "G10417XF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13585JF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10417XF", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G10425AY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G10425AY] could be generated at this time" }, { "glytoucan_ac": "G10425SO", "notes": [], "error": "No pathways for [G10425SO] could be generated at this time" }, { "glytoucan_ac": "G10440YK", "notes": [], "error": "No pathways for [G10440YK] could be generated at this time" }, { "glytoucan_ac": "G10448ZR", "notes": [], "error": "No pathways for [G10448ZR] could be generated at this time" }, { "glytoucan_ac": "G10470SE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50489VC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G10470SE", "dp": 17 } ], "links": [ { "target": "G10470SE", "source": "G50489VC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10483PN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10733HY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 }, { "id": "G10483PN", "dp": 12 } ], "links": [ { "target": "G10483PN", "source": "G10733HY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10529ZR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96113SZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G82420SH", "dp": 10 }, { "id": "G96113SZ", "dp": 11 }, { "id": "G10529ZR", "dp": 11 } ], "links": [ { "target": "G10529ZR", "source": "G96113SZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96113SZ", "source": "G82420SH", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82420SH", "source": "G45262QY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10540LB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G10540LB] could be generated at this time" }, { "glytoucan_ac": "G10563SE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G10563SE] could be generated at this time" }, { "glytoucan_ac": "G10578GY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G17155VX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G10578GY", "dp": 16 } ], "links": [ { "target": "G10578GY", "source": "G17155VX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10614GM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 } ], "links": [ { "target": "G10614GM", "source": "G10209QU", "residue_affected": { "residue_id": "N275", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10614XK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G38637SA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10614XK", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G10627KR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47175EF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G47175EF", "dp": 11 }, { "id": "G10627KR", "dp": 11 } ], "links": [ { "target": "G10627KR", "source": "G47175EF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10637WE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50278HE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10637WE", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G10650OV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G10650OV] could be generated at this time" }, { "glytoucan_ac": "G10664FL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 } ], "links": [ { "target": "G10664FL", "source": "G45262QY", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10666VQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30569KZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G04185VX", "dp": 10 }, { "id": "G30569KZ", "dp": 11 }, { "id": "G10666VQ", "dp": 11 } ], "links": [ { "target": "G10666VQ", "source": "G30569KZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30569KZ", "source": "G04185VX", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04185VX", "source": "G36191CD", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10691MJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 } ], "links": [ { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10694XU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G74120DW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10694XU", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G10700RM", "notes": [], "error": "No pathways for [G10700RM] could be generated at this time" }, { "glytoucan_ac": "G10716SX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G37385TT", "dp": 11 } ], "links": [ { "target": "G10716SX", "source": "G37385TT", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G37385TT", "source": "G88417ED", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10725II", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G10733HY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10741VJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74107UT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74107UT", "dp": 11 }, { "id": "G10741VJ", "dp": 11 } ], "links": [ { "target": "G10741VJ", "source": "G74107UT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74107UT", "source": "G78059CC", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10770RR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G82033VN", "dp": 14 } ], "links": [ { "target": "G10770RR", "source": "G82033VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G82033VN", "source": "G20926BB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10805TH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39213VZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10805TH", "dp": 7 } ], "links": [ { "target": "G10805TH", "source": "G39213VZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10835DD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59752BW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10835DD", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G10844WB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G56591LC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 }, { "id": "G10844WB", "dp": 10 } ], "links": [ { "target": "G10844WB", "source": "G56591LC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10845BX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74238CC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G10845BX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G10874QT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 } ], "links": [ { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10881VB", "notes": [], "error": "No pathways for [G10881VB] could be generated at this time" }, { "glytoucan_ac": "G10897DJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G14512NS", "dp": 9 }, { "id": "G72893LL", "dp": 10 } ], "links": [ { "target": "G10897DJ", "source": "G72893LL", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G72893LL", "source": "G14512NS", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G14512NS", "source": "G24420RT", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G10920IN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G10965EB", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G10965EB] could be generated at this time" }, { "glytoucan_ac": "G10989IB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 }, { "id": "G95404EQ", "dp": 17 }, { "id": "G31004HS", "dp": 18 } ], "links": [ { "target": "G10989IB", "source": "G31004HS", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G31004HS", "source": "G95404EQ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11010AN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G11010AN] could be generated at this time" }, { "glytoucan_ac": "G11012KS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 } ], "links": [ { "target": "G11012KS", "source": "G37046CZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11034PZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 } ], "links": [ { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11041DA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 } ], "links": [ { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11052OE", "notes": [], "error": "No pathways for [G11052OE] could be generated at this time" }, { "glytoucan_ac": "G11058EJ", "notes": [], "error": "No pathways for [G11058EJ] could be generated at this time" }, { "glytoucan_ac": "G11075DR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14938IR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11075DR", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G11165BC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G11165BC] could be generated at this time" }, { "glytoucan_ac": "G11180GU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G11189WY", "notes": [], "error": "No pathways for [G11189WY] could be generated at this time" }, { "glytoucan_ac": "G11213NA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81738MQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11213NA", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G11249YX", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G87192TH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11249YX", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G11256DQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G70945OS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 }, { "id": "G70945OS", "dp": 13 }, { "id": "G11256DQ", "dp": 13 } ], "links": [ { "target": "G11256DQ", "source": "G70945OS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70945OS", "source": "G41331JX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11278YL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 } ], "links": [ { "target": "G11278YL", "source": "G42672MA", "residue_affected": { "residue_id": "N72", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11282GU", "notes": [], "error": "No pathways for [G11282GU] could be generated at this time" }, { "glytoucan_ac": "G11286QT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16753NR]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G11286QT", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G11350UX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17134VG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11350UX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G11365AH", "notes": [], "error": "No pathways for [G11365AH] could be generated at this time" }, { "glytoucan_ac": "G11376KE", "notes": [], "error": "No pathways for [G11376KE] could be generated at this time" }, { "glytoucan_ac": "G11402KL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08062CY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11402KL", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G11450BY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G57345HS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11450BY", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G11460AB", "notes": [], "error": "No pathways for [G11460AB] could be generated at this time" }, { "glytoucan_ac": "G11479AN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85106DS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11479AN", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G11509RN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 } ], "links": [ { "target": "G11509RN", "source": "G30302VM", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11535IB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 } ], "links": [ { "target": "G11535IB", "source": "G59471TH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11540FP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G11551UU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G11588II", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 }, { "id": "G01010HW", "dp": 9 } ], "links": [ { "target": "G11588II", "source": "G01010HW", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11615SW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G73817GH", "dp": 10 }, { "id": "G57601AP", "dp": 11 } ], "links": [ { "target": "G11615SW", "source": "G57601AP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G57601AP", "source": "G73817GH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11635LG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G11635LG] could be generated at this time" }, { "glytoucan_ac": "G11637WL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11641YE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G04185VX", "dp": 10 }, { "id": "G30569KZ", "dp": 11 } ], "links": [ { "target": "G11641YE", "source": "G30569KZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G30569KZ", "source": "G04185VX", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04185VX", "source": "G36191CD", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11671GQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G11671GQ] could be generated at this time" }, { "glytoucan_ac": "G11679NT", "notes": [], "error": "No pathways for [G11679NT] could be generated at this time" }, { "glytoucan_ac": "G11696PX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G73211XU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 }, { "id": "G95919TI", "dp": 14 }, { "id": "G73211XU", "dp": 15 }, { "id": "G11696PX", "dp": 15 } ], "links": [ { "target": "G11696PX", "source": "G73211XU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73211XU", "source": "G95919TI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95919TI", "source": "G30651IU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11700UP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98559XP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G98559XP", "dp": 14 }, { "id": "G11700UP", "dp": 14 } ], "links": [ { "target": "G11700UP", "source": "G98559XP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98559XP", "source": "G18938DW", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11712ZQ", "notes": [], "error": "No pathways for [G11712ZQ] could be generated at this time" }, { "glytoucan_ac": "G11721NX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G42909GK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G11721NX", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G11740AG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93075HW]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G40289RO", "dp": 10 }, { "id": "G71102UV", "dp": 11 }, { "id": "G93075HW", "dp": 12 }, { "id": "G11740AG", "dp": 12 } ], "links": [ { "target": "G11740AG", "source": "G93075HW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93075HW", "source": "G71102UV", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71102UV", "source": "G40289RO", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G40289RO", "source": "G20966TZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11745DB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G73817GH", "dp": 10 }, { "id": "G57601AP", "dp": 11 }, { "id": "G11615SW", "dp": 12 } ], "links": [ { "target": "G11745DB", "source": "G11615SW", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G11615SW", "source": "G57601AP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G57601AP", "source": "G73817GH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11745XZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 } ], "links": [ { "target": "G11745XZ", "source": "G84467IZ", "residue_affected": { "residue_id": "N299", "pubchem_name": "Fuc", "anomer": "b", "absolute": "L", "form_name": "Fucp", "full_name": "β-L-Fucp" }, "effect": "Adds β-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11818HY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G00536FZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G00536FZ", "dp": 12 }, { "id": "G11818HY", "dp": 12 } ], "links": [ { "target": "G11818HY", "source": "G00536FZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00536FZ", "source": "G71679MX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11823ZO", "notes": [], "error": "No pathways for [G11823ZO] could be generated at this time" }, { "glytoucan_ac": "G11885NX", "notes": [], "error": "No pathways for [G11885NX] could be generated at this time" }, { "glytoucan_ac": "G11910RR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 } ], "links": [ { "target": "G11910RR", "source": "G89877QI", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11929CD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G11929CD", "source": "G09782JM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11929SN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 } ], "links": [ { "target": "G11929SN", "source": "G80294GH", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11953VE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 } ], "links": [ { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11960UF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09482NW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G11960UF", "dp": 9 } ], "links": [ { "target": "G11960UF", "source": "G09482NW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G11994QC", "notes": [], "error": "No pathways for [G11994QC] could be generated at this time" }, { "glytoucan_ac": "G12061IK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12086GM", "notes": [], "error": "No pathways for [G12086GM] could be generated at this time" }, { "glytoucan_ac": "G12110NN", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 } ], "links": [ { "target": "G12110NN", "source": "G13151XE", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12174PW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G12174PW", "source": "G39213VZ", "residue_affected": { "residue_id": "N488", "pubchem_name": "Man", "anomer": "b", "absolute": "D", "form_name": "Manp", "full_name": "β-D-Manp" }, "effect": "Adds β-D-Manp", "enzymes": [] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12187FG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10650OV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12187FG", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G12203WB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G46021KV", "dp": 12 } ], "links": [ { "target": "G12203WB", "source": "G46021KV", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G46021KV", "source": "G29857RC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12222NC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G12222NC] could be generated at this time" }, { "glytoucan_ac": "G12241WD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G12241WD] could be generated at this time" }, { "glytoucan_ac": "G12254MW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G38407OC", "dp": 12 }, { "id": "G95233RZ", "dp": 13 } ], "links": [ { "target": "G12254MW", "source": "G95233RZ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G95233RZ", "source": "G38407OC", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38407OC", "source": "G20815TK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12266SO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G12274AS", "notes": [], "error": "No pathways for [G12274AS] could be generated at this time" }, { "glytoucan_ac": "G12318EJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G66313YW", "dp": 13 } ], "links": [ { "target": "G12318EJ", "source": "G66313YW", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66313YW", "source": "G74645FT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12352RJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04783EJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12352RJ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G12378KS", "notes": [], "error": "No pathways for [G12378KS] could be generated at this time" }, { "glytoucan_ac": "G12398HZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12406MX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G59915YZ", "dp": 11 }, { "id": "G98380JU", "dp": 12 } ], "links": [ { "target": "G12406MX", "source": "G98380JU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98380JU", "source": "G59915YZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59915YZ", "source": "G79609RF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12438DW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G67410LQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12438DW", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G12438YM", "notes": [], "error": "No pathways for [G12438YM] could be generated at this time" }, { "glytoucan_ac": "G12450CJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G90564EX", "dp": 11 }, { "id": "G08949VK", "dp": 12 } ], "links": [ { "target": "G12450CJ", "source": "G08949VK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G08949VK", "source": "G90564EX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90564EX", "source": "G28826SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12472CC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 } ], "links": [ { "target": "G12472CC", "source": "G43299SD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12474XI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74286KY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12474XI", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G12504XV", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G12504XV", "source": "G08520NM", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G12524BD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G86102AA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G86102AA", "dp": 11 }, { "id": "G12524BD", "dp": 11 } ], "links": [ { "target": "G12524BD", "source": "G86102AA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86102AA", "source": "G85542KD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12531EE", "notes": [], "error": "No pathways for [G12531EE] could be generated at this time" }, { "glytoucan_ac": "G12561VS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G12593TX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G07483YN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12593TX", "dp": 7 } ], "links": [ { "target": "G12593TX", "source": "G07483YN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12594VB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G12594VB] could be generated at this time" }, { "glytoucan_ac": "G12631FF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G74074HU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12631FF", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G12643KN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G34175ZP", "dp": 10 } ], "links": [ { "target": "G12643KN", "source": "G34175ZP", "residue_affected": { "residue_id": "N302", "pubchem_name": "GlcNAc", "anomer": "a", "absolute": "D", "form_name": "GlcpNAc", "full_name": "α-D-GlcpNAc" }, "effect": "Adds α-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G34175ZP", "source": "G01265XZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12679LF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38291RB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G38291RB", "dp": 13 }, { "id": "G12679LF", "dp": 13 } ], "links": [ { "target": "G12679LF", "source": "G38291RB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38291RB", "source": "G45359RY", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12699VT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G12699VT", "source": "G78059CC", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12704ID", "notes": [], "error": "No pathways for [G12704ID] could be generated at this time" }, { "glytoucan_ac": "G12715AH", "notes": [], "error": "No pathways for [G12715AH] could be generated at this time" }, { "glytoucan_ac": "G12715RL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G41596PV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12715RL", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G12727SF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G12740VA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12757LB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89143RS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12757LB", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G12762FV", "notes": [], "error": "No pathways for [G12762FV] could be generated at this time" }, { "glytoucan_ac": "G12764SQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72411HX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12764SQ", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G12788PX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G12788PX] could be generated at this time" }, { "glytoucan_ac": "G12802HY", "notes": [], "error": "No pathways for [G12802HY] could be generated at this time" }, { "glytoucan_ac": "G12852SA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G83845ZV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G12852SA", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G12861CT", "notes": [], "error": "No pathways for [G12861CT] could be generated at this time" }, { "glytoucan_ac": "G12878NK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G81923ER]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 }, { "id": "G12878NK", "dp": 10 } ], "links": [ { "target": "G12878NK", "source": "G81923ER", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G12991XQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G35096EN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G35096EN", "dp": 10 }, { "id": "G12991XQ", "dp": 10 } ], "links": [ { "target": "G12991XQ", "source": "G35096EN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G35096EN", "source": "G20030CU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13006TG", "notes": [], "error": "No pathways for [G13006TG] could be generated at this time" }, { "glytoucan_ac": "G13049QY", "notes": [], "error": "No pathways for [G13049QY] could be generated at this time" }, { "glytoucan_ac": "G13055JW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G14938IR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G13055JW", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G13074BX", "notes": [], "error": "No pathways for [G13074BX] could be generated at this time" }, { "glytoucan_ac": "G13091NP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G19726AG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G13091NP", "dp": 13 } ], "links": [ { "target": "G13091NP", "source": "G19726AG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13113SB", "notes": [], "error": "No pathways for [G13113SB] could be generated at this time" }, { "glytoucan_ac": "G13151XE", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13156PQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 } ], "links": [ { "target": "G13156PQ", "source": "G53752TA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13181ZZ", "notes": [], "error": "No pathways for [G13181ZZ] could be generated at this time" }, { "glytoucan_ac": "G13210XL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G13210XL] could be generated at this time" }, { "glytoucan_ac": "G13267ZY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G13267ZY", "source": "G46638GC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13282WA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G13282WA] could be generated at this time" }, { "glytoucan_ac": "G13291XJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G02934UB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 }, { "id": "G02934UB", "dp": 14 }, { "id": "G13291XJ", "dp": 14 } ], "links": [ { "target": "G13291XJ", "source": "G02934UB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02934UB", "source": "G99074EO", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13305QJ", "notes": [], "error": "No pathways for [G13305QJ] could be generated at this time" }, { "glytoucan_ac": "G13322RS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G13322RS] could be generated at this time" }, { "glytoucan_ac": "G13335AQ", "notes": [], "error": "No pathways for [G13335AQ] could be generated at this time" }, { "glytoucan_ac": "G13441KG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08709JB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G08709JB", "dp": 13 }, { "id": "G13441KG", "dp": 13 } ], "links": [ { "target": "G13441KG", "source": "G08709JB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08709JB", "source": "G45359RY", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13477HM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82357WL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G82357WL", "dp": 11 }, { "id": "G13477HM", "dp": 11 } ], "links": [ { "target": "G13477HM", "source": "G82357WL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82357WL", "source": "G28826SH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13495RN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72974NP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 }, { "id": "G01354KL", "dp": 14 }, { "id": "G72974NP", "dp": 15 }, { "id": "G13495RN", "dp": 15 } ], "links": [ { "target": "G13495RN", "source": "G72974NP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72974NP", "source": "G01354KL", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01354KL", "source": "G41611UP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13515ZY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79344MI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 }, { "id": "G13515ZY", "dp": 12 } ], "links": [ { "target": "G13515ZY", "source": "G79344MI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13535FD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G13535FD] could be generated at this time" }, { "glytoucan_ac": "G13537KO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G13583BZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36108GD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G36108GD", "dp": 11 }, { "id": "G13583BZ", "dp": 11 } ], "links": [ { "target": "G13583BZ", "source": "G36108GD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36108GD", "source": "G32305RZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13585JF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G13585JF] could be generated at this time" }, { "glytoucan_ac": "G13592VY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G13592VY", "source": "G69411IG", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13614FV", "notes": [], "error": "No pathways for [G13614FV] could be generated at this time" }, { "glytoucan_ac": "G13646GG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G13657KC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54953LX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G13657KC", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G13659RH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G13659RH] could be generated at this time" }, { "glytoucan_ac": "G13672YG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41331JX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 }, { "id": "G13672YG", "dp": 12 } ], "links": [ { "target": "G13672YG", "source": "G41331JX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13687TQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82861UH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G82861UH", "dp": 9 }, { "id": "G13687TQ", "dp": 9 } ], "links": [ { "target": "G13687TQ", "source": "G82861UH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82861UH", "source": "G59471TH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13688QP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G36316RB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G13688QP", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G13720TX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24402OX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G66098KC", "dp": 14 }, { "id": "G24402OX", "dp": 15 }, { "id": "G13720TX", "dp": 15 } ], "links": [ { "target": "G13720TX", "source": "G24402OX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G24402OX", "source": "G66098KC", "residue_affected": { "residue_id": "N37", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66098KC", "source": "G18938DW", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13744OG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G13744OG] could be generated at this time" }, { "glytoucan_ac": "G13746SQ", "notes": [], "error": "No pathways for [G13746SQ] could be generated at this time" }, { "glytoucan_ac": "G13836YR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G33909XJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 }, { "id": "G33909XJ", "dp": 11 }, { "id": "G13836YR", "dp": 11 } ], "links": [ { "target": "G13836YR", "source": "G33909XJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33909XJ", "source": "G81923ER", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13843CF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G13865MD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G13869TL", "notes": [], "error": "No pathways for [G13869TL] could be generated at this time" }, { "glytoucan_ac": "G13909GK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53288JQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G13909GK", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G13964RX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G70374KJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G70374KJ", "dp": 11 }, { "id": "G13964RX", "dp": 11 } ], "links": [ { "target": "G13964RX", "source": "G70374KJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70374KJ", "source": "G88417ED", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G13974DV", "notes": [], "error": "No pathways for [G13974DV] could be generated at this time" }, { "glytoucan_ac": "G13976WV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G73492AT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G13976WV", "dp": 13 } ], "links": [ { "target": "G13976WV", "source": "G73492AT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14015IL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75308SV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G88966ZO", "dp": 15 }, { "id": "G75308SV", "dp": 16 }, { "id": "G14015IL", "dp": 16 } ], "links": [ { "target": "G14015IL", "source": "G75308SV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75308SV", "source": "G88966ZO", "residue_affected": { "residue_id": "N37", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88966ZO", "source": "G63889NK", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14020CV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G30569KZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G04185VX", "dp": 10 }, { "id": "G30569KZ", "dp": 11 }, { "id": "G14020CV", "dp": 11 } ], "links": [ { "target": "G14020CV", "source": "G30569KZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30569KZ", "source": "G04185VX", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04185VX", "source": "G36191CD", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14047PA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G14047PA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14068WV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 } ], "links": [ { "target": "G14068WV", "source": "G04743RS", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14077SN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G14095XN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G20018DL", "dp": 14 } ], "links": [ { "target": "G14095XN", "source": "G20018DL", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G20018DL", "source": "G18938DW", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14127XU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 } ], "links": [ { "target": "G14127XU", "source": "G91023GB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14190WK", "notes": [], "error": "No pathways for [G14190WK] could be generated at this time" }, { "glytoucan_ac": "G14201CU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G73492AT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G14201CU", "dp": 13 } ], "links": [ { "target": "G14201CU", "source": "G73492AT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14233VW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G27844UM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G14233VW", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G14307KB", "notes": [], "error": "No pathways for [G14307KB] could be generated at this time" }, { "glytoucan_ac": "G14311HQ", "notes": [], "error": "No pathways for [G14311HQ] could be generated at this time" }, { "glytoucan_ac": "G14354BD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G47606XQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G26320VO", "dp": 10 }, { "id": "G47606XQ", "dp": 11 }, { "id": "G14354BD", "dp": 11 } ], "links": [ { "target": "G14354BD", "source": "G47606XQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47606XQ", "source": "G26320VO", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26320VO", "source": "G58667NI", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14356TR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G42240DE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G42240DE", "dp": 12 }, { "id": "G14356TR", "dp": 12 } ], "links": [ { "target": "G14356TR", "source": "G42240DE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G42240DE", "source": "G20815TK", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14371YU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G14373ZY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G73211XU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 }, { "id": "G95919TI", "dp": 14 }, { "id": "G73211XU", "dp": 15 }, { "id": "G14373ZY", "dp": 15 } ], "links": [ { "target": "G14373ZY", "source": "G73211XU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73211XU", "source": "G95919TI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95919TI", "source": "G30651IU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14393TF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G14393TF] could be generated at this time" }, { "glytoucan_ac": "G14428PM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G14428PM] could be generated at this time" }, { "glytoucan_ac": "G14431ZQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98906WL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G14431ZQ", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G14438ZT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17168RO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 }, { "id": "G14438ZT", "dp": 14 } ], "links": [ { "target": "G14438ZT", "source": "G17168RO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14488UY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 } ], "links": [ { "target": "G14488UY", "source": "G60564DP", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14491HM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G64761FU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G14491HM", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G14492PU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G27946NT", "dp": 9 } ], "links": [ { "target": "G14492PU", "source": "G27946NT", "residue_affected": { "residue_id": "N72", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G27946NT", "source": "G24420RT", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14510SZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G14512NS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 } ], "links": [ { "target": "G14512NS", "source": "G24420RT", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14520ZO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G14520ZO] could be generated at this time" }, { "glytoucan_ac": "G14549GA", "notes": [], "error": "No pathways for [G14549GA] could be generated at this time" }, { "glytoucan_ac": "G14576KZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07483YN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G14576KZ", "dp": 7 } ], "links": [ { "target": "G14576KZ", "source": "G07483YN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14615WQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G14615WQ] could be generated at this time" }, { "glytoucan_ac": "G14617QG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G26756VT", "dp": 11 } ], "links": [ { "target": "G14617QG", "source": "G26756VT", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26756VT", "source": "G08863NS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14675SI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G90703DJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G14675SI", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G14761OA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G78503JC", "dp": 12 } ], "links": [ { "target": "G14761OA", "source": "G78503JC", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14767DF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G14767DF", "source": "G69411IG", "residue_affected": { "residue_id": "N205", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14782PJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 } ], "links": [ { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14809NR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51490BW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G14809NR", "dp": 8 } ], "links": [ { "target": "G14809NR", "source": "G51490BW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14838TI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G14840SZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G14854WL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50779LX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 }, { "id": "G50779LX", "dp": 12 }, { "id": "G14854WL", "dp": 12 } ], "links": [ { "target": "G14854WL", "source": "G50779LX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50779LX", "source": "G25140TA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14888AE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G14888AE] could be generated at this time" }, { "glytoucan_ac": "G14899VS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26264SQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G42028DN", "dp": 11 }, { "id": "G26264SQ", "dp": 12 }, { "id": "G14899VS", "dp": 12 } ], "links": [ { "target": "G14899VS", "source": "G26264SQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26264SQ", "source": "G42028DN", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G42028DN", "source": "G09921WG", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14905AZ", "notes": [], "error": "No pathways for [G14905AZ] could be generated at this time" }, { "glytoucan_ac": "G14905MK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 } ], "links": [ { "target": "G14905MK", "source": "G61207RZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14927KP", "notes": [], "error": "No pathways for [G14927KP] could be generated at this time" }, { "glytoucan_ac": "G14938IR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G14938IR] could be generated at this time" }, { "glytoucan_ac": "G14942ZU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75853FN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G14942ZU", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G14959WS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 } ], "links": [ { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14996IQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G14996IQ", "source": "G69411IG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G14998UC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 } ], "links": [ { "target": "G14998UC", "source": "G25140TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15001YX", "notes": [], "error": "No pathways for [G15001YX] could be generated at this time" }, { "glytoucan_ac": "G15006PM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G96674LJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G96674LJ", "dp": 18 }, { "id": "G15006PM", "dp": 18 } ], "links": [ { "target": "G15006PM", "source": "G96674LJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96674LJ", "source": "G50489VC", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15103WJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G15103WJ", "source": "G25520XG", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15112UU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86321OX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G15112UU", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G15158LV", "notes": [], "error": "No pathways for [G15158LV] could be generated at this time" }, { "glytoucan_ac": "G15164ZG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53000RQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 }, { "id": "G53000RQ", "dp": 11 }, { "id": "G15164ZG", "dp": 11 } ], "links": [ { "target": "G15164ZG", "source": "G53000RQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53000RQ", "source": "G12740VA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15192BD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G15204IM", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G94297FY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G94297FY", "dp": 9 }, { "id": "G15204IM", "dp": 9 } ], "links": [ { "target": "G15204IM", "source": "G94297FY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94297FY", "source": "G29492IF", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15216UP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G55314RK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G15216UP", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G15222RS", "notes": [], "error": "No pathways for [G15222RS] could be generated at this time" }, { "glytoucan_ac": "G15269NF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G17413FR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 }, { "id": "G17413FR", "dp": 13 }, { "id": "G15269NF", "dp": 13 } ], "links": [ { "target": "G15269NF", "source": "G17413FR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17413FR", "source": "G56749GV", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15317IZ", "notes": [], "error": "No pathways for [G15317IZ] could be generated at this time" }, { "glytoucan_ac": "G15329MZ", "notes": [], "error": "No pathways for [G15329MZ] could be generated at this time" }, { "glytoucan_ac": "G15355KC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41087ZA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G15355KC", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G15355XO", "notes": [], "error": "No pathways for [G15355XO] could be generated at this time" }, { "glytoucan_ac": "G15403PA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G55479DB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G11929SN", "dp": 14 }, { "id": "G55479DB", "dp": 15 }, { "id": "G15403PA", "dp": 15 } ], "links": [ { "target": "G15403PA", "source": "G55479DB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G55479DB", "source": "G11929SN", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G11929SN", "source": "G80294GH", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15503SL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G42548XF", "dp": 7 }, { "id": "G95956WE", "dp": 8 } ], "links": [ { "target": "G15503SL", "source": "G95956WE", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95956WE", "source": "G42548XF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42548XF", "source": "G61751GZ", "residue_affected": { "residue_id": "N204", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] } ] } , { "glytoucan_ac": "G15522RV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G15527QL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32173NW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G15527QL", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G15571KX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G15591FI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G75107JX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G15591FI", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G15638PX", "notes": [], "error": "No pathways for [G15638PX] could be generated at this time" }, { "glytoucan_ac": "G15681WF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G15681WF] could be generated at this time" }, { "glytoucan_ac": "G15696PP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G01727PW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G15696PP", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G15727JK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G15727JK", "source": "G69411IG", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15730FJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G15732HH", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G15732HH", "source": "G08520NM", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G15751RX", "notes": [], "error": "No pathways for [G15751RX] could be generated at this time" }, { "glytoucan_ac": "G15825OT", "notes": [], "error": "No pathways for [G15825OT] could be generated at this time" }, { "glytoucan_ac": "G15828WB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G88382QE", "dp": 14 } ], "links": [ { "target": "G15828WB", "source": "G88382QE", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G88382QE", "source": "G18938DW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15859AU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G15859AU] could be generated at this time" }, { "glytoucan_ac": "G15972DM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39601JQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G15972DM", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G15987FM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95998QK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 }, { "id": "G49827WK", "dp": 11 }, { "id": "G95998QK", "dp": 12 }, { "id": "G15987FM", "dp": 12 } ], "links": [ { "target": "G15987FM", "source": "G95998QK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95998QK", "source": "G49827WK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G49827WK", "source": "G09446VC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G15998WM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 } ], "links": [ { "target": "G15998WM", "source": "G79950YS", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16038YA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G33742YO", "dp": 9 } ], "links": [ { "target": "G16038YA", "source": "G33742YO", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16057DE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 } ], "links": [ { "target": "G16057DE", "source": "G95898GD", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16119YF", "notes": [], "error": "No pathways for [G16119YF] could be generated at this time" }, { "glytoucan_ac": "G16150CJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 } ], "links": [ { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16155TD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 } ], "links": [ { "target": "G16155TD", "source": "G01669LU", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16201LW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G14996IQ", "dp": 8 } ], "links": [ { "target": "G16201LW", "source": "G14996IQ", "residue_affected": { "residue_id": "N224", "pubchem_name": "Fuc", "anomer": "b", "absolute": "D", "form_name": "Fucp", "full_name": "β-D-Fucp" }, "effect": "Adds β-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G14996IQ", "source": "G69411IG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16276IK", "notes": [], "error": "No pathways for [G16276IK] could be generated at this time" }, { "glytoucan_ac": "G16293AI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G74645FT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G16293AI", "dp": 12 } ], "links": [ { "target": "G16293AI", "source": "G74645FT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16325IK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11635LG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16325IK", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G16341ZC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G57943ZV", "dp": 11 } ], "links": [ { "target": "G16341ZC", "source": "G57943ZV", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G57943ZV", "source": "G52934AK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16344ZG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47975JA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G47975JA", "dp": 12 }, { "id": "G16344ZG", "dp": 12 } ], "links": [ { "target": "G16344ZG", "source": "G47975JA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47975JA", "source": "G11041DA", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16397GM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94045IP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G94045IP", "dp": 13 }, { "id": "G16397GM", "dp": 13 } ], "links": [ { "target": "G16397GM", "source": "G94045IP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94045IP", "source": "G91023GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16403CC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96719MC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16403CC", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G16404YH", "notes": [], "error": "No pathways for [G16404YH] could be generated at this time" }, { "glytoucan_ac": "G16437LH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G16437LH] could be generated at this time" }, { "glytoucan_ac": "G16441MS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G16451PE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 } ], "links": [ { "target": "G16451PE", "source": "G62504BU", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16464LC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 } ], "links": [ { "target": "G16464LC", "source": "G43694RQ", "residue_affected": { "residue_id": "N322", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16481GK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G51562OR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16481GK", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G16520OZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G56591LC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 }, { "id": "G16520OZ", "dp": 10 } ], "links": [ { "target": "G16520OZ", "source": "G56591LC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16523AO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16529MG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 } ], "links": [ { "target": "G16529MG", "source": "G56549DH", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16546ZZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 } ], "links": [ { "target": "G16546ZZ", "source": "G41331JX", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16588UI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G16588UI", "source": "G78059CC", "residue_affected": { "residue_id": "N483", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16600BL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G16600BL] could be generated at this time" }, { "glytoucan_ac": "G16614GV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06374YY]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G06374YY", "dp": 10 }, { "id": "G16614GV", "dp": 10 } ], "links": [ { "target": "G16614GV", "source": "G06374YY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06374YY", "source": "G16828VN", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16679DU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G69086TY", "dp": 12 }, { "id": "G42400JK", "dp": 13 } ], "links": [ { "target": "G16679DU", "source": "G42400JK", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G42400JK", "source": "G69086TY", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16717IV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G29011JC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G16717IV", "dp": 8 } ], "links": [ { "target": "G16717IV", "source": "G29011JC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16733YD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G09670SR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G09670SR", "dp": 10 }, { "id": "G16733YD", "dp": 10 } ], "links": [ { "target": "G16733YD", "source": "G09670SR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16743OM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20983SP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G94531EZ", "dp": 18 }, { "id": "G20983SP", "dp": 19 }, { "id": "G16743OM", "dp": 19 } ], "links": [ { "target": "G16743OM", "source": "G20983SP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20983SP", "source": "G94531EZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16743PO", "notes": [], "error": "No pathways for [G16743PO] could be generated at this time" }, { "glytoucan_ac": "G16753NR", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G16753NR] could be generated at this time" }, { "glytoucan_ac": "G16759KR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16768LX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G78059CC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G16768LX", "dp": 10 } ], "links": [ { "target": "G16768LX", "source": "G78059CC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16774YZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 } ], "links": [ { "target": "G16774YZ", "source": "G86696LV", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16778ZK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95298UR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16778ZK", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G16782SL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G55645TD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16782SL", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G16809IL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71812IK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G71812IK", "dp": 9 }, { "id": "G16809IL", "dp": 9 } ], "links": [ { "target": "G16809IL", "source": "G71812IK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71812IK", "source": "G80858MF", "residue_affected": { "residue_id": "N322", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16827VK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G16827VK] could be generated at this time" }, { "glytoucan_ac": "G16828VN", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G16873YG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G16873YG] could be generated at this time" }, { "glytoucan_ac": "G16879YK", "notes": [], "error": "No pathways for [G16879YK] could be generated at this time" }, { "glytoucan_ac": "G16921OK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06594DV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16921OK", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G16932ML", "notes": [], "error": "No pathways for [G16932ML] could be generated at this time" }, { "glytoucan_ac": "G16938IW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G83635VI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16938IW", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G16956YO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G16956YO] could be generated at this time" }, { "glytoucan_ac": "G16967GJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G16976BN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08076GP]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G16976BN", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G16986CA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82847HG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G16986CA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G16999DQ", "notes": [], "error": "No pathways for [G16999DQ] could be generated at this time" }, { "glytoucan_ac": "G17029BL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G59579TL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G86753CK", "dp": 17 }, { "id": "G59579TL", "dp": 18 }, { "id": "G17029BL", "dp": 18 } ], "links": [ { "target": "G17029BL", "source": "G59579TL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59579TL", "source": "G86753CK", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86753CK", "source": "G02311IE", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17029IU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46638GC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G17029IU", "dp": 9 } ], "links": [ { "target": "G17029IU", "source": "G46638GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17041TR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G17041TR] could be generated at this time" }, { "glytoucan_ac": "G17107VB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99935CU]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 }, { "id": "G99969SS", "dp": 10 }, { "id": "G99935CU", "dp": 11 }, { "id": "G17107VB", "dp": 11 } ], "links": [ { "target": "G17107VB", "source": "G99935CU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99935CU", "source": "G99969SS", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G99969SS", "source": "G13151XE", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17120XF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G06969ZX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 }, { "id": "G17120XF", "dp": 10 } ], "links": [ { "target": "G17120XF", "source": "G06969ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17134VG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G17134VG] could be generated at this time" }, { "glytoucan_ac": "G17140UR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G17140UR] could be generated at this time" }, { "glytoucan_ac": "G17153CQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84964KJ", "dp": 12 } ], "links": [ { "target": "G17153CQ", "source": "G84964KJ", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84964KJ", "source": "G29857RC", "residue_affected": { "residue_id": "N130", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17155VX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 } ], "links": [ { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17157SF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G63838JW]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G30588SI", "dp": 9 }, { "id": "G63838JW", "dp": 10 }, { "id": "G17157SF", "dp": 10 } ], "links": [ { "target": "G17157SF", "source": "G63838JW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63838JW", "source": "G30588SI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30588SI", "source": "G08520NM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17160IJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27776PG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G27776PG", "dp": 9 }, { "id": "G17160IJ", "dp": 9 } ], "links": [ { "target": "G17160IJ", "source": "G27776PG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G27776PG", "source": "G20956ZK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17164DX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G17168RO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 } ], "links": [ { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17172ZR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39540XG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G25835MT", "dp": 10 }, { "id": "G10258MC", "dp": 11 }, { "id": "G39540XG", "dp": 12 }, { "id": "G17172ZR", "dp": 12 } ], "links": [ { "target": "G17172ZR", "source": "G39540XG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39540XG", "source": "G10258MC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10258MC", "source": "G25835MT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17207FU", "notes": [], "error": "No pathways for [G17207FU] could be generated at this time" }, { "glytoucan_ac": "G17213JF", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 } ], "links": [ { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17226QK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G95956WE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G42548XF", "dp": 7 }, { "id": "G95956WE", "dp": 8 }, { "id": "G17226QK", "dp": 8 } ], "links": [ { "target": "G17226QK", "source": "G95956WE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95956WE", "source": "G42548XF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42548XF", "source": "G61751GZ", "residue_affected": { "residue_id": "N204", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] } ] } , { "glytoucan_ac": "G17228YV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G40542QP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 }, { "id": "G40542QP", "dp": 15 }, { "id": "G17228YV", "dp": 15 } ], "links": [ { "target": "G17228YV", "source": "G40542QP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40542QP", "source": "G10228OD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17264LS", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G17264LS", "source": "G16828VN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17274VA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65981EG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G37385TT", "dp": 11 }, { "id": "G65981EG", "dp": 12 }, { "id": "G17274VA", "dp": 12 } ], "links": [ { "target": "G17274VA", "source": "G65981EG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65981EG", "source": "G37385TT", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G37385TT", "source": "G88417ED", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17286ZM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G78503JC", "dp": 12 }, { "id": "G86202BL", "dp": 13 } ], "links": [ { "target": "G17286ZM", "source": "G86202BL", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G86202BL", "source": "G78503JC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17297XR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G03296OS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G17297XR", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G17336FF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75896PD]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [G75896PD] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G17339LD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G52770HR", "dp": 10 } ], "links": [ { "target": "G17339LD", "source": "G52770HR", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G52770HR", "source": "G36191CD", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17344FG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G94490EL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G17344FG", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G17348SA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72112RK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G17348SA", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G17389EH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03948VT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G17389EH", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G17413FR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 } ], "links": [ { "target": "G17413FR", "source": "G56749GV", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17437BX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 } ], "links": [ { "target": "G17437BX", "source": "G92359VA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17441MI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98366ZJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 }, { "id": "G98366ZJ", "dp": 14 }, { "id": "G17441MI", "dp": 14 } ], "links": [ { "target": "G17441MI", "source": "G98366ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98366ZJ", "source": "G99074EO", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17465IO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G17465IO] could be generated at this time" }, { "glytoucan_ac": "G17473NR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 } ], "links": [ { "target": "G17473NR", "source": "G10733HY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17490CY", "notes": [], "error": "No pathways for [G17490CY] could be generated at this time" }, { "glytoucan_ac": "G17540HT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 } ], "links": [ { "target": "G17540HT", "source": "G30460NZ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17540MV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G02679YX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G17540MV", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G17595XL", "notes": [], "error": "No pathways for [G17595XL] could be generated at this time" }, { "glytoucan_ac": "G17597KD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G41953RN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G17597KD", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G17639DA", "notes": [], "error": "No pathways for [G17639DA] could be generated at this time" }, { "glytoucan_ac": "G17652NI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G01342FO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G17652NI", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G17689DH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 } ], "links": [ { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17698NO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39089YD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G17698NO", "dp": 7 } ], "links": [ { "target": "G17698NO", "source": "G39089YD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G17740GV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 } ], "links": [ { "target": "G17740GV", "source": "G89877QI", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17751FJ", "notes": [], "error": "No pathways for [G17751FJ] could be generated at this time" }, { "glytoucan_ac": "G17779DH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G17779DH] could be generated at this time" }, { "glytoucan_ac": "G17800QD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G12398HZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G17800QD", "dp": 8 } ], "links": [ { "target": "G17800QD", "source": "G12398HZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17801HD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81392TU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 }, { "id": "G81392TU", "dp": 14 }, { "id": "G17801HD", "dp": 14 } ], "links": [ { "target": "G17801HD", "source": "G81392TU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G81392TU", "source": "G85085MS", "residue_affected": { "residue_id": "N246", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17807LO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50078RT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G50078RT", "dp": 12 }, { "id": "G17807LO", "dp": 12 } ], "links": [ { "target": "G17807LO", "source": "G50078RT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50078RT", "source": "G79809MM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17820VB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G99270AV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 }, { "id": "G17820VB", "dp": 10 } ], "links": [ { "target": "G17820VB", "source": "G99270AV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17848HM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 } ], "links": [ { "target": "G17848HM", "source": "G85767HW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17857ZF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 }, { "id": "G57970NA", "dp": 13 } ], "links": [ { "target": "G17857ZF", "source": "G57970NA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G57970NA", "source": "G49515VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17863YV", "notes": [], "error": "No pathways for [G17863YV] could be generated at this time" }, { "glytoucan_ac": "G17875TE", "notes": [], "error": "No pathways for [G17875TE] could be generated at this time" }, { "glytoucan_ac": "G17909DH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17964DY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G17964DY] could be generated at this time" }, { "glytoucan_ac": "G17964XN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G43346PX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 }, { "id": "G43346PX", "dp": 12 }, { "id": "G17964XN", "dp": 12 } ], "links": [ { "target": "G17964XN", "source": "G43346PX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43346PX", "source": "G04743RS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G17968CJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G63065KG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G17968CJ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G17977UE", "notes": [], "error": "No pathways for [G17977UE] could be generated at this time" }, { "glytoucan_ac": "G17988XO", "notes": [], "error": "No pathways for [G17988XO] could be generated at this time" }, { "glytoucan_ac": "G17996ZO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G76136FD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G23626NI", "dp": 11 }, { "id": "G76136FD", "dp": 12 }, { "id": "G17996ZO", "dp": 12 } ], "links": [ { "target": "G17996ZO", "source": "G76136FD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76136FD", "source": "G23626NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G23626NI", "source": "G85542KD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18026EK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 } ], "links": [ { "target": "G18026EK", "source": "G37046CZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18082CO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10691MJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G18082CO", "dp": 11 } ], "links": [ { "target": "G18082CO", "source": "G10691MJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18125MC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G18157KC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G18157KC] could be generated at this time" }, { "glytoucan_ac": "G18160VJ", "notes": [], "error": "No pathways for [G18160VJ] could be generated at this time" }, { "glytoucan_ac": "G18165XJ", "notes": [], "error": "No pathways for [G18165XJ] could be generated at this time" }, { "glytoucan_ac": "G18196JE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G14520ZO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G18196JE", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G18219CJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18223CA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G33241WC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G33241WC", "dp": 15 }, { "id": "G18223CA", "dp": 15 } ], "links": [ { "target": "G18223CA", "source": "G33241WC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33241WC", "source": "G45720CA", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18264WJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G30901GC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G30901GC", "dp": 9 }, { "id": "G18264WJ", "dp": 9 } ], "links": [ { "target": "G18264WJ", "source": "G30901GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30901GC", "source": "G79348ZY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18286BM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G68283NG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G18286BM", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G18306LO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59575FI]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G03275SD", "dp": 10 }, { "id": "G66129DI", "dp": 11 }, { "id": "G59575FI", "dp": 12 }, { "id": "G18306LO", "dp": 12 } ], "links": [ { "target": "G18306LO", "source": "G59575FI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59575FI", "source": "G66129DI", "residue_affected": { "residue_id": "N476", "pubchem_name": "phosphate", "anomer": "n", "absolute": "n", "form_name": "phosphate", "full_name": "-n-phosphate" }, "effect": "Adds -n-phosphate", "enzymes": [] }, { "target": "G66129DI", "source": "G03275SD", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18340ZI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27223CU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G27223CU", "dp": 12 }, { "id": "G18340ZI", "dp": 12 } ], "links": [ { "target": "G18340ZI", "source": "G27223CU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G27223CU", "source": "G82252QI", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18410AS", "notes": [], "error": "No pathways for [G18410AS] could be generated at this time" }, { "glytoucan_ac": "G18506AD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G51367TM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G18506AD", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G18516QW", "notes": [], "error": "No pathways for [G18516QW] could be generated at this time" }, { "glytoucan_ac": "G18581LO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 } ], "links": [ { "target": "G18581LO", "source": "G19726AG", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18584GW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21756MV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G18584GW", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G18594ZT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G18594ZT] could be generated at this time" }, { "glytoucan_ac": "G18614BQ", "notes": [], "error": "No pathways for [G18614BQ] could be generated at this time" }, { "glytoucan_ac": "G18687CN", "notes": [], "error": "No pathways for [G18687CN] could be generated at this time" }, { "glytoucan_ac": "G18724OW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03075ZE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G03075ZE", "dp": 14 }, { "id": "G18724OW", "dp": 14 } ], "links": [ { "target": "G18724OW", "source": "G03075ZE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03075ZE", "source": "G04989WY", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18731YM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G49515VE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 }, { "id": "G18731YM", "dp": 12 } ], "links": [ { "target": "G18731YM", "source": "G49515VE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18738PX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G64761FU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G18738PX", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G18768EK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 } ], "links": [ { "target": "G18768EK", "source": "G78803YD", "residue_affected": { "residue_id": "N78", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18784ZP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 } ], "links": [ { "target": "G18784ZP", "source": "G78155FK", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18803CK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G00951UF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G79198BK", "dp": 9 }, { "id": "G00951UF", "dp": 10 }, { "id": "G18803CK", "dp": 10 } ], "links": [ { "target": "G18803CK", "source": "G00951UF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00951UF", "source": "G79198BK", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G79198BK", "source": "G10219AA", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18814PP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G18859UG", "notes": [], "error": "No pathways for [G18859UG] could be generated at this time" }, { "glytoucan_ac": "G18869TR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G18869TR", "source": "G46638GC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18875WG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G18877VR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79457WN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G79457WN", "dp": 11 }, { "id": "G18877VR", "dp": 11 } ], "links": [ { "target": "G18877VR", "source": "G79457WN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79457WN", "source": "G00176HZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18905AN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21319HP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G40906DZ", "dp": 14 }, { "id": "G21319HP", "dp": 15 }, { "id": "G18905AN", "dp": 15 } ], "links": [ { "target": "G18905AN", "source": "G21319HP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21319HP", "source": "G40906DZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G40906DZ", "source": "G18938DW", "residue_affected": { "residue_id": "N43", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18913QB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94363RH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 }, { "id": "G94363RH", "dp": 17 }, { "id": "G18913QB", "dp": 17 } ], "links": [ { "target": "G18913QB", "source": "G94363RH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94363RH", "source": "G79950YS", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18938DW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 } ], "links": [ { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G18948TG", "notes": [], "error": "No pathways for [G18948TG] could be generated at this time" }, { "glytoucan_ac": "G18956GV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G18956GV] could be generated at this time" }, { "glytoucan_ac": "G19019TY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G09670SR", "dp": 10 } ], "links": [ { "target": "G19019TY", "source": "G09670SR", "residue_affected": { "residue_id": "N72", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19026NP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G19026NP] could be generated at this time" }, { "glytoucan_ac": "G19053XS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19726AG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G19053XS", "dp": 13 } ], "links": [ { "target": "G19053XS", "source": "G19726AG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19083SI", "notes": [], "error": "No pathways for [G19083SI] could be generated at this time" }, { "glytoucan_ac": "G19103IX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G19103IX] could be generated at this time" }, { "glytoucan_ac": "G19104OH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G19104OH] could be generated at this time" }, { "glytoucan_ac": "G19106CR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56271TF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G56271TF", "dp": 8 }, { "id": "G19106CR", "dp": 8 } ], "links": [ { "target": "G19106CR", "source": "G56271TF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56271TF", "source": "G59741XZ", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19124KK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 } ], "links": [ { "target": "G19124KK", "source": "G84467IZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19140RD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G28747XN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G96921ZU", "dp": 12 }, { "id": "G28747XN", "dp": 13 }, { "id": "G19140RD", "dp": 13 } ], "links": [ { "target": "G19140RD", "source": "G28747XN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28747XN", "source": "G96921ZU", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96921ZU", "source": "G11041DA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19173US", "notes": [], "error": "No pathways for [G19173US] could be generated at this time" }, { "glytoucan_ac": "G19226BI", "notes": [], "error": "No pathways for [G19226BI] could be generated at this time" }, { "glytoucan_ac": "G19242QH", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G19242QH] could be generated at this time" }, { "glytoucan_ac": "G19243TV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G72580QS", "dp": 14 } ], "links": [ { "target": "G19243TV", "source": "G72580QS", "residue_affected": { "residue_id": "N130", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [] }, { "target": "G72580QS", "source": "G66282NU", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19267AT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G07228BR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G07228BR", "dp": 10 }, { "id": "G19267AT", "dp": 10 } ], "links": [ { "target": "G19267AT", "source": "G07228BR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07228BR", "source": "G93500PH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19281RB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95490LA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G95490LA", "dp": 14 }, { "id": "G19281RB", "dp": 14 } ], "links": [ { "target": "G19281RB", "source": "G95490LA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95490LA", "source": "G18938DW", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19287UY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46503KK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G46503KK", "dp": 12 }, { "id": "G19287UY", "dp": 12 } ], "links": [ { "target": "G19287UY", "source": "G46503KK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46503KK", "source": "G18219CJ", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19289JN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G19294RF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G31037WG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G31037WG", "dp": 18 }, { "id": "G19294RF", "dp": 18 } ], "links": [ { "target": "G19294RF", "source": "G31037WG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31037WG", "source": "G92574YO", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19310VN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G32201IL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G19310VN", "dp": 10 } ], "links": [ { "target": "G19310VN", "source": "G32201IL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19429IT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03385XG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G03385XG", "dp": 13 }, { "id": "G19429IT", "dp": 13 } ], "links": [ { "target": "G19429IT", "source": "G03385XG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03385XG", "source": "G01669LU", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19430NR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76422GC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 }, { "id": "G76422GC", "dp": 12 }, { "id": "G19430NR", "dp": 12 } ], "links": [ { "target": "G19430NR", "source": "G76422GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76422GC", "source": "G25140TA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19444JC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 } ], "links": [ { "target": "G19444JC", "source": "G45720CA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19447ZX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23295TF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G23295TF", "dp": 10 }, { "id": "G19447ZX", "dp": 10 } ], "links": [ { "target": "G19447ZX", "source": "G23295TF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23295TF", "source": "G27919IH", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19469VZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 } ], "links": [ { "target": "G19469VZ", "source": "G92574YO", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19483RZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G19520XO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42438ZG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G19520XO", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G19532EC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95081VM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G95081VM", "dp": 9 }, { "id": "G19532EC", "dp": 9 } ], "links": [ { "target": "G19532EC", "source": "G95081VM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95081VM", "source": "G66937TJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19537TS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G87807PF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G19537TS", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G19541IU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74859XI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G19541IU", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G19553VJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G26182BM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G19553VJ", "dp": 8 } ], "links": [ { "target": "G19553VJ", "source": "G26182BM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19592AH", "notes": [], "error": "No pathways for [G19592AH] could be generated at this time" }, { "glytoucan_ac": "G19607EP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G60439QY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 }, { "id": "G37990ZT", "dp": 15 }, { "id": "G99891PR", "dp": 16 }, { "id": "G60439QY", "dp": 17 }, { "id": "G19607EP", "dp": 17 } ], "links": [ { "target": "G19607EP", "source": "G60439QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60439QY", "source": "G99891PR", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99891PR", "source": "G37990ZT", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19615BB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 }, { "id": "G08242BT", "dp": 12 } ], "links": [ { "target": "G19615BB", "source": "G08242BT", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G08242BT", "source": "G26949IX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19636RY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G19677EK", "notes": [], "error": "No pathways for [G19677EK] could be generated at this time" }, { "glytoucan_ac": "G19687OL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G19687OL] could be generated at this time" }, { "glytoucan_ac": "G19697JA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G33742YO", "dp": 9 }, { "id": "G47859DD", "dp": 10 } ], "links": [ { "target": "G19697JA", "source": "G47859DD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G47859DD", "source": "G33742YO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19726AG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 } ], "links": [ { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19739KB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G19739KB] could be generated at this time" }, { "glytoucan_ac": "G19747OA", "notes": [], "error": "No pathways for [G19747OA] could be generated at this time" }, { "glytoucan_ac": "G19763QB", "notes": [], "error": "No pathways for [G19763QB] could be generated at this time" }, { "glytoucan_ac": "G19790PJ", "notes": [], "error": "No pathways for [G19790PJ] could be generated at this time" }, { "glytoucan_ac": "G19839OY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G62504BU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G19839OY", "dp": 10 } ], "links": [ { "target": "G19839OY", "source": "G62504BU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19841IT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82942ZJ]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G82942ZJ", "dp": 9 }, { "id": "G19841IT", "dp": 9 } ], "links": [ { "target": "G19841IT", "source": "G82942ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82942ZJ", "source": "G08520NM", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19843TY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 } ], "links": [ { "target": "G19843TY", "source": "G27919IH", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19854PG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 } ], "links": [ { "target": "G19854PG", "source": "G56549DH", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19868AX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G19868AX", "source": "G39213VZ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19886LH", "notes": [], "error": "No pathways for [G19886LH] could be generated at this time" }, { "glytoucan_ac": "G19894RH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G93500PH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G19894RH", "dp": 9 } ], "links": [ { "target": "G19894RH", "source": "G93500PH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19906BM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G20096RP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G20096RP", "dp": 12 }, { "id": "G19906BM", "dp": 12 } ], "links": [ { "target": "G19906BM", "source": "G20096RP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20096RP", "source": "G25520XG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19943KG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G74090KZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G74090KZ", "dp": 7 }, { "id": "G19943KG", "dp": 7 } ], "links": [ { "target": "G19943KG", "source": "G74090KZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74090KZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G19949UL", "notes": [], "error": "No pathways for [G19949UL] could be generated at this time" }, { "glytoucan_ac": "G19958IL", "notes": [], "error": "No pathways for [G19958IL] could be generated at this time" }, { "glytoucan_ac": "G20018DL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G20018DL", "source": "G18938DW", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20021PB", "notes": [], "error": "No pathways for [G20021PB] could be generated at this time" }, { "glytoucan_ac": "G20030CU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20034RK", "notes": [], "error": "No pathways for [G20034RK] could be generated at this time" }, { "glytoucan_ac": "G20064NM", "notes": [], "error": "No pathways for [G20064NM] could be generated at this time" }, { "glytoucan_ac": "G20079RG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71013KY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G20079RG", "dp": 10 } ], "links": [ { "target": "G20079RG", "source": "G71013KY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20096RP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G20096RP", "source": "G25520XG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20140JS", "notes": [], "error": "No pathways for [G20140JS] could be generated at this time" }, { "glytoucan_ac": "G20167OW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 } ], "links": [ { "target": "G20167OW", "source": "G25140TA", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20168MP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G02290KA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G02290KA", "dp": 10 }, { "id": "G20168MP", "dp": 10 } ], "links": [ { "target": "G20168MP", "source": "G02290KA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02290KA", "source": "G20030CU", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20170YB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 } ], "links": [ { "target": "G20170YB", "source": "G63585HN", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20172ET", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G43351VW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20172ET", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G20173ZW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13151XE]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 }, { "id": "G20173ZW", "dp": 9 } ], "links": [ { "target": "G20173ZW", "source": "G13151XE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20174ZL", "notes": [], "error": "No pathways for [G20174ZL] could be generated at this time" }, { "glytoucan_ac": "G20212GT", "notes": [], "error": "No pathways for [G20212GT] could be generated at this time" }, { "glytoucan_ac": "G20248TO", "notes": [], "error": "No pathways for [G20248TO] could be generated at this time" }, { "glytoucan_ac": "G20266PH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 } ], "links": [ { "target": "G20266PH", "source": "G84467IZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20284VH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13156PQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G13156PQ", "dp": 12 }, { "id": "G20284VH", "dp": 12 } ], "links": [ { "target": "G20284VH", "source": "G13156PQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G13156PQ", "source": "G53752TA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20410RW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G20410RW] could be generated at this time" }, { "glytoucan_ac": "G20426LM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10563SE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20426LM", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G20449BJ", "notes": [], "error": "No pathways for [G20449BJ] could be generated at this time" }, { "glytoucan_ac": "G20455AW", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G42130KX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20455AW", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G20463HA", "notes": [], "error": "No pathways for [G20463HA] could be generated at this time" }, { "glytoucan_ac": "G20512LK", "notes": [], "error": "No pathways for [G20512LK] could be generated at this time" }, { "glytoucan_ac": "G20544CY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G08493GY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20544CY", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G20551LK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 } ], "links": [ { "target": "G20551LK", "source": "G62504BU", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20621ZX", "notes": [], "error": "No pathways for [G20621ZX] could be generated at this time" }, { "glytoucan_ac": "G20624LQ", "notes": [], "error": "No pathways for [G20624LQ] could be generated at this time" }, { "glytoucan_ac": "G20636FS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25731WL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20636FS", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G20662UG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80943NY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20662UG", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G20692QU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G77475MM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20692QU", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G20711NK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G20711NK] could be generated at this time" }, { "glytoucan_ac": "G20720CG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G20720CG] could be generated at this time" }, { "glytoucan_ac": "G20758LC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G62619LG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20758LC", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G20815TK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 } ], "links": [ { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20873FQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G33742YO", "dp": 9 }, { "id": "G47859DD", "dp": 10 }, { "id": "G19697JA", "dp": 11 } ], "links": [ { "target": "G20873FQ", "source": "G19697JA", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19697JA", "source": "G47859DD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G47859DD", "source": "G33742YO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20877ZV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13210XL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G20877ZV", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G20885BK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G20885BK] could be generated at this time" }, { "glytoucan_ac": "G20894MY", "notes": [], "error": "No pathways for [G20894MY] could be generated at this time" }, { "glytoucan_ac": "G20924UR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G20924UR] could be generated at this time" }, { "glytoucan_ac": "G20926BB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 } ], "links": [ { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20946SK", "notes": [], "error": "No pathways for [G20946SK] could be generated at this time" }, { "glytoucan_ac": "G20953SW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G19444JC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G19444JC", "dp": 15 }, { "id": "G20953SW", "dp": 15 } ], "links": [ { "target": "G20953SW", "source": "G19444JC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19444JC", "source": "G45720CA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20956ZK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20966TZ", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G20983SP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G94531EZ", "dp": 18 } ], "links": [ { "target": "G20983SP", "source": "G94531EZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21005TQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14996IQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G14996IQ", "dp": 8 }, { "id": "G21005TQ", "dp": 8 } ], "links": [ { "target": "G21005TQ", "source": "G14996IQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14996IQ", "source": "G69411IG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21050RT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G21050RT] could be generated at this time" }, { "glytoucan_ac": "G21072IJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59746QC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G59746QC", "dp": 14 }, { "id": "G21072IJ", "dp": 14 } ], "links": [ { "target": "G21072IJ", "source": "G59746QC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59746QC", "source": "G00909PI", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21100JS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G78503JC", "dp": 12 }, { "id": "G86202BL", "dp": 13 }, { "id": "G17286ZM", "dp": 14 } ], "links": [ { "target": "G21100JS", "source": "G17286ZM", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G17286ZM", "source": "G86202BL", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G86202BL", "source": "G78503JC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21109OS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G21130MT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 }, { "id": "G58403SV", "dp": 11 } ], "links": [ { "target": "G21130MT", "source": "G58403SV", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G58403SV", "source": "G99270AV", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21167TN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61707PW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 }, { "id": "G74928QN", "dp": 14 }, { "id": "G61707PW", "dp": 15 }, { "id": "G21167TN", "dp": 15 } ], "links": [ { "target": "G21167TN", "source": "G61707PW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61707PW", "source": "G74928QN", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G74928QN", "source": "G29449JO", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21219OJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94163JZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G21219OJ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G21246OH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G21246OH", "source": "G00176HZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21251LN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G59471TH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G21251LN", "dp": 8 } ], "links": [ { "target": "G21251LN", "source": "G59471TH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21311PN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79348ZY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G21311PN", "dp": 8 } ], "links": [ { "target": "G21311PN", "source": "G79348ZY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21311YA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G21311YA", "source": "G11041DA", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21319HP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G40906DZ", "dp": 14 } ], "links": [ { "target": "G21319HP", "source": "G40906DZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G40906DZ", "source": "G18938DW", "residue_affected": { "residue_id": "N43", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21342EB", "notes": [], "error": "No pathways for [G21342EB] could be generated at this time" }, { "glytoucan_ac": "G21359LU", "notes": [], "error": "No pathways for [G21359LU] could be generated at this time" }, { "glytoucan_ac": "G21359NQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 } ], "links": [ { "target": "G21359NQ", "source": "G32305RZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21380FF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G68946DB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G76528ZS", "dp": 11 }, { "id": "G68946DB", "dp": 12 }, { "id": "G21380FF", "dp": 12 } ], "links": [ { "target": "G21380FF", "source": "G68946DB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G68946DB", "source": "G76528ZS", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G76528ZS", "source": "G52934AK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21411AR", "notes": [], "error": "No pathways for [G21411AR] could be generated at this time" }, { "glytoucan_ac": "G21421NG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G43040IL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G21421NG", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G21454AE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38022PE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G21454AE", "dp": 14 } ], "links": [ { "target": "G21454AE", "source": "G38022PE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21459ST", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G21459ST] could be generated at this time" }, { "glytoucan_ac": "G21470TX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10770RR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G82033VN", "dp": 14 }, { "id": "G10770RR", "dp": 15 }, { "id": "G21470TX", "dp": 15 } ], "links": [ { "target": "G21470TX", "source": "G10770RR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10770RR", "source": "G82033VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G82033VN", "source": "G20926BB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21498SM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G21513QX", "notes": [], "error": "No pathways for [G21513QX] could be generated at this time" }, { "glytoucan_ac": "G21627CA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09826WW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G09826WW", "dp": 11 }, { "id": "G21627CA", "dp": 11 } ], "links": [ { "target": "G21627CA", "source": "G09826WW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09826WW", "source": "G85542KD", "residue_affected": { "residue_id": "N271", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21679ID", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G21679ID", "source": "G52934AK", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21729HC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G18026EK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G18026EK", "dp": 12 }, { "id": "G21729HC", "dp": 12 } ], "links": [ { "target": "G21729HC", "source": "G18026EK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18026EK", "source": "G37046CZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21737WY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G94531EZ", "dp": 18 } ], "links": [ { "target": "G21737WY", "source": "G94531EZ", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21755KD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21756MV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G21756MV] could be generated at this time" }, { "glytoucan_ac": "G21767ND", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91550OH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G21767ND", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G21788RU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G21788RU", "source": "G25520XG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21898KP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 } ], "links": [ { "target": "G21898KP", "source": "G90870DG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21916IS", "notes": [], "error": "No pathways for [G21916IS] could be generated at this time" }, { "glytoucan_ac": "G21925JZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G21925JZ", "source": "G36191CD", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21927IY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72260GO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 }, { "id": "G72260GO", "dp": 12 }, { "id": "G21927IY", "dp": 12 } ], "links": [ { "target": "G21927IY", "source": "G72260GO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72260GO", "source": "G04743RS", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21929YV", "notes": [ "reducing end mismatch [o-D-GlcNAc]", "homologous pathway end-point [G43299SD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G21929YV", "dp": 9 } ], "links": [ { "target": "G21929YV", "source": "G43299SD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21969LH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39029JR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G39029JR", "dp": 10 }, { "id": "G21969LH", "dp": 10 } ], "links": [ { "target": "G21969LH", "source": "G39029JR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39029JR", "source": "G93500PH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G21969UD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43040IL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G21969UD", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G22018VM", "notes": [], "error": "No pathways for [G22018VM] could be generated at this time" }, { "glytoucan_ac": "G22043HZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G22079SE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G68845SP", "dp": 14 } ], "links": [ { "target": "G22079SE", "source": "G68845SP", "residue_affected": { "residue_id": "N48", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G68845SP", "source": "G18938DW", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22098NU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 } ], "links": [ { "target": "G22098NU", "source": "G71013KY", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22107KA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 } ], "links": [ { "target": "G22107KA", "source": "G08863NS", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22117HL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G22117NA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45777DE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G26939ZY", "dp": 8 }, { "id": "G45777DE", "dp": 9 }, { "id": "G22117NA", "dp": 9 } ], "links": [ { "target": "G22117NA", "source": "G45777DE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45777DE", "source": "G26939ZY", "residue_affected": { "residue_id": "N305", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G26939ZY", "source": "G39213VZ", "residue_affected": { "residue_id": "N306", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22122FL", "notes": [], "error": "No pathways for [G22122FL] could be generated at this time" }, { "glytoucan_ac": "G22137KZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G42022OY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G22137KZ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G22146HW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78555BT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G82540VC", "dp": 8 }, { "id": "G41278YY", "dp": 9 }, { "id": "G78555BT", "dp": 10 }, { "id": "G22146HW", "dp": 10 } ], "links": [ { "target": "G22146HW", "source": "G78555BT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78555BT", "source": "G41278YY", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G41278YY", "source": "G82540VC", "residue_affected": { "residue_id": "N238", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G82540VC", "source": "G39213VZ", "residue_affected": { "residue_id": "N250", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22188XM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G44005DK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G22188XM", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G22230QR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G77485UZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G22230QR", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G22237ZE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99943EE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G22237ZE", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G22246QW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65796FM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 }, { "id": "G65796FM", "dp": 13 }, { "id": "G22246QW", "dp": 13 } ], "links": [ { "target": "G22246QW", "source": "G65796FM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65796FM", "source": "G79344MI", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22254MF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 }, { "id": "G05546WG", "dp": 9 } ], "links": [ { "target": "G22254MF", "source": "G05546WG", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G05546WG", "source": "G69812OF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22330AF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G51490BW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G22330AF", "dp": 8 } ], "links": [ { "target": "G22330AF", "source": "G51490BW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22354SF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G22354SF] could be generated at this time" }, { "glytoucan_ac": "G22361XJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 } ], "links": [ { "target": "G22361XJ", "source": "G04791QM", "residue_affected": { "residue_id": "N267", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22387ST", "notes": [], "error": "No pathways for [G22387ST] could be generated at this time" }, { "glytoucan_ac": "G22388FD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G22388FD] could be generated at this time" }, { "glytoucan_ac": "G22437MC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77537OB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 }, { "id": "G77537OB", "dp": 11 }, { "id": "G22437MC", "dp": 11 } ], "links": [ { "target": "G22437MC", "source": "G77537OB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77537OB", "source": "G03445UI", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22467XI", "notes": [], "error": "No pathways for [G22467XI] could be generated at this time" }, { "glytoucan_ac": "G22477EB", "notes": [], "error": "No pathways for [G22477EB] could be generated at this time" }, { "glytoucan_ac": "G22550VJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 } ], "links": [ { "target": "G22550VJ", "source": "G45262QY", "residue_affected": { "residue_id": "N135", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22558JP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G22558JP] could be generated at this time" }, { "glytoucan_ac": "G22571UF", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G83594ZB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G11929CD", "dp": 10 }, { "id": "G26795PW", "dp": 11 }, { "id": "G83594ZB", "dp": 12 }, { "id": "G22571UF", "dp": 12 } ], "links": [ { "target": "G22571UF", "source": "G83594ZB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G83594ZB", "source": "G26795PW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G26795PW", "source": "G11929CD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G11929CD", "source": "G09782JM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22587DK", "notes": [], "error": "No pathways for [G22587DK] could be generated at this time" }, { "glytoucan_ac": "G22678XU", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G17264LS", "dp": 10 } ], "links": [ { "target": "G22678XU", "source": "G17264LS", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G17264LS", "source": "G16828VN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22686TA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98366ZJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 }, { "id": "G98366ZJ", "dp": 14 }, { "id": "G22686TA", "dp": 14 } ], "links": [ { "target": "G22686TA", "source": "G98366ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98366ZJ", "source": "G99074EO", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22728HO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G54584ER", "dp": 14 } ], "links": [ { "target": "G22728HO", "source": "G54584ER", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G54584ER", "source": "G18938DW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22732WO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G22754FQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G56749GV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 }, { "id": "G22754FQ", "dp": 12 } ], "links": [ { "target": "G22754FQ", "source": "G56749GV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22768VO", "notes": [], "error": "No pathways for [G22768VO] could be generated at this time" }, { "glytoucan_ac": "G22795QB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 } ], "links": [ { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22836DF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59655SA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G59655SA", "dp": 12 }, { "id": "G22836DF", "dp": 12 } ], "links": [ { "target": "G22836DF", "source": "G59655SA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59655SA", "source": "G53752TA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22865RK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G22865RK] could be generated at this time" }, { "glytoucan_ac": "G22898PA", "notes": [], "error": "No pathways for [G22898PA] could be generated at this time" }, { "glytoucan_ac": "G22914HB", "notes": [], "error": "No pathways for [G22914HB] could be generated at this time" }, { "glytoucan_ac": "G22927MQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G58768FH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G22927MQ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G22946YB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93107BF]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G93107BF", "dp": 11 }, { "id": "G22946YB", "dp": 11 } ], "links": [ { "target": "G22946YB", "source": "G93107BF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93107BF", "source": "G11637WL", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G22949KX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20711NK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G22949KX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G22979QH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G28948UC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G28948UC", "dp": 12 }, { "id": "G22979QH", "dp": 12 } ], "links": [ { "target": "G22979QH", "source": "G28948UC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28948UC", "source": "G10691MJ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23060KN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 } ], "links": [ { "target": "G23060KN", "source": "G09446VC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23117SI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69812OF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 }, { "id": "G23117SI", "dp": 8 } ], "links": [ { "target": "G23117SI", "source": "G69812OF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23142YD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G84852GW", "dp": 9 } ], "links": [ { "target": "G23142YD", "source": "G84852GW", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G84852GW", "source": "G12398HZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23166NU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G23166NU] could be generated at this time" }, { "glytoucan_ac": "G23210FC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G61088TM", "dp": 12 }, { "id": "G57843KJ", "dp": 13 } ], "links": [ { "target": "G23210FC", "source": "G57843KJ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G57843KJ", "source": "G61088TM", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61088TM", "source": "G90870DG", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23290TL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G23295TF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 } ], "links": [ { "target": "G23295TF", "source": "G27919IH", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23296IL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00662IB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G23296IL", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G23340ZN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G71835BN", "dp": 10 }, { "id": "G01378OV", "dp": 11 } ], "links": [ { "target": "G23340ZN", "source": "G01378OV", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01378OV", "source": "G71835BN", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G71835BN", "source": "G36191CD", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23342BO", "notes": [], "error": "No pathways for [G23342BO] could be generated at this time" }, { "glytoucan_ac": "G23345GE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G42686NQ", "dp": 14 } ], "links": [ { "target": "G23345GE", "source": "G42686NQ", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G42686NQ", "source": "G19726AG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23377WN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G03864MI", "dp": 11 } ], "links": [ { "target": "G23377WN", "source": "G03864MI", "residue_affected": { "residue_id": "N483", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G03864MI", "source": "G78059CC", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23416CI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04743RS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 }, { "id": "G23416CI", "dp": 11 } ], "links": [ { "target": "G23416CI", "source": "G04743RS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23416IW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G67782JV", "dp": 12 } ], "links": [ { "target": "G23416IW", "source": "G67782JV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67782JV", "source": "G35310KA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23416VJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19019TY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G09670SR", "dp": 10 }, { "id": "G19019TY", "dp": 11 }, { "id": "G23416VJ", "dp": 11 } ], "links": [ { "target": "G23416VJ", "source": "G19019TY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19019TY", "source": "G09670SR", "residue_affected": { "residue_id": "N72", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23419AQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G23419AQ] could be generated at this time" }, { "glytoucan_ac": "G23436FC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G23458QH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 }, { "id": "G66572SF", "dp": 13 } ], "links": [ { "target": "G23458QH", "source": "G66572SF", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G66572SF", "source": "G48658PB", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23484GM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G69086TY", "dp": 12 }, { "id": "G42400JK", "dp": 13 } ], "links": [ { "target": "G23484GM", "source": "G42400JK", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G42400JK", "source": "G69086TY", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23511JD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G23546LY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G23546LY] could be generated at this time" }, { "glytoucan_ac": "G23572BH", "notes": [], "error": "No pathways for [G23572BH] could be generated at this time" }, { "glytoucan_ac": "G23577TY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G23577TY] could be generated at this time" }, { "glytoucan_ac": "G23598DU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G70511VE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G70511VE", "dp": 12 }, { "id": "G23598DU", "dp": 12 } ], "links": [ { "target": "G23598DU", "source": "G70511VE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70511VE", "source": "G53752TA", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23601EL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G33742YO", "dp": 9 } ], "links": [ { "target": "G23601EL", "source": "G33742YO", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23616ZX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 } ], "links": [ { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23626NI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 } ], "links": [ { "target": "G23626NI", "source": "G85542KD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23647WB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30553WH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G30553WH", "dp": 9 }, { "id": "G23647WB", "dp": 9 } ], "links": [ { "target": "G23647WB", "source": "G30553WH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30553WH", "source": "G20956ZK", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23667XV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82779CI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G23667XV", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G23709VK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G82357WL", "dp": 11 } ], "links": [ { "target": "G23709VK", "source": "G82357WL", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G82357WL", "source": "G28826SH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23711JB", "notes": [], "error": "No pathways for [G23711JB] could be generated at this time" }, { "glytoucan_ac": "G23718VU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G23722TU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G83926PC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 }, { "id": "G01354KL", "dp": 14 }, { "id": "G83926PC", "dp": 15 }, { "id": "G23722TU", "dp": 15 } ], "links": [ { "target": "G23722TU", "source": "G83926PC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G83926PC", "source": "G01354KL", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01354KL", "source": "G41611UP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23726CO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59159PE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G23726CO", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G23765TI", "notes": [], "error": "No pathways for [G23765TI] could be generated at this time" }, { "glytoucan_ac": "G23770JR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G23770JR", "source": "G36191CD", "residue_affected": { "residue_id": "N299", "pubchem_name": "Fuc", "anomer": "b", "absolute": "L", "form_name": "Fucp", "full_name": "β-L-Fucp" }, "effect": "Adds β-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23782KP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G23782KP] could be generated at this time" }, { "glytoucan_ac": "G23795SX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69600TI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 }, { "id": "G69600TI", "dp": 9 }, { "id": "G23795SX", "dp": 9 } ], "links": [ { "target": "G23795SX", "source": "G69600TI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69600TI", "source": "G64669AQ", "residue_affected": { "residue_id": "N477", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylf", "full_name": "β-D-Xylf" }, "effect": "Adds β-D-Xylf", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G23799GS", "notes": [], "error": "No pathways for [G23799GS] could be generated at this time" }, { "glytoucan_ac": "G23805AC", "notes": [], "error": "No pathways for [G23805AC] could be generated at this time" }, { "glytoucan_ac": "G23817OE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25326BM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G25326BM", "dp": 9 }, { "id": "G23817OE", "dp": 9 } ], "links": [ { "target": "G23817OE", "source": "G25326BM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25326BM", "source": "G89993FE", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23819TW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G93582HM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G23819TW", "dp": 13 } ], "links": [ { "target": "G23819TW", "source": "G93582HM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23824AT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 } ], "links": [ { "target": "G23824AT", "source": "G56591LC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23824XF", "notes": [], "error": "No pathways for [G23824XF] could be generated at this time" }, { "glytoucan_ac": "G23897ET", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78980OK]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G23897ET", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G23901NY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G23901NY", "source": "G52934AK", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23914JN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G23914JN] could be generated at this time" }, { "glytoucan_ac": "G23934WD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G52770HR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G52770HR", "dp": 10 }, { "id": "G23934WD", "dp": 10 } ], "links": [ { "target": "G23934WD", "source": "G52770HR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52770HR", "source": "G36191CD", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G23946TS", "notes": [], "error": "No pathways for [G23946TS] could be generated at this time" }, { "glytoucan_ac": "G23949TZ", "notes": [], "error": "No pathways for [G23949TZ] could be generated at this time" }, { "glytoucan_ac": "G23980PE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G72718TT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G23980PE", "dp": 9 } ], "links": [ { "target": "G23980PE", "source": "G72718TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24046UO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G40341NV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G24046UO", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G24094XC", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G93265QH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G57117TO", "dp": 8 }, { "id": "G93265QH", "dp": 9 }, { "id": "G24094XC", "dp": 9 } ], "links": [ { "target": "G24094XC", "source": "G93265QH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93265QH", "source": "G57117TO", "residue_affected": { "residue_id": "N224", "pubchem_name": "Fuc", "anomer": "b", "absolute": "D", "form_name": "Fucp", "full_name": "β-D-Fucp" }, "effect": "Adds β-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G57117TO", "source": "G69411IG", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24095BS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G24095BS] could be generated at this time" }, { "glytoucan_ac": "G24121ID", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G32305RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G24121ID", "dp": 10 } ], "links": [ { "target": "G24121ID", "source": "G32305RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24122ZI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60227QI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G24122ZI", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G24125FE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21737WY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G94531EZ", "dp": 18 }, { "id": "G21737WY", "dp": 19 }, { "id": "G24125FE", "dp": 19 } ], "links": [ { "target": "G24125FE", "source": "G21737WY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21737WY", "source": "G94531EZ", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24155DW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G24155DW] could be generated at this time" }, { "glytoucan_ac": "G24172SG", "notes": [], "error": "No pathways for [G24172SG] could be generated at this time" }, { "glytoucan_ac": "G24229GD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47384NK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G24229GD", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G24284HU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88928GI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G88928GI", "dp": 12 }, { "id": "G24284HU", "dp": 12 } ], "links": [ { "target": "G24284HU", "source": "G88928GI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88928GI", "source": "G11041DA", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24284KU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G15998WM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 }, { "id": "G15998WM", "dp": 17 }, { "id": "G24284KU", "dp": 17 } ], "links": [ { "target": "G24284KU", "source": "G15998WM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G15998WM", "source": "G79950YS", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24292VT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93464IM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G24292VT", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G24305IZ", "notes": [], "error": "No pathways for [G24305IZ] could be generated at this time" }, { "glytoucan_ac": "G24327OK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G24327OK] could be generated at this time" }, { "glytoucan_ac": "G24329OK", "notes": [], "error": "No pathways for [G24329OK] could be generated at this time" }, { "glytoucan_ac": "G24336IA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65867II]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G24336IA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G24346JZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57675TR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G24346JZ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G24355OK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G15828WB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G88382QE", "dp": 14 }, { "id": "G15828WB", "dp": 15 }, { "id": "G24355OK", "dp": 15 } ], "links": [ { "target": "G24355OK", "source": "G15828WB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G15828WB", "source": "G88382QE", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G88382QE", "source": "G18938DW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24364HL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23060KN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 }, { "id": "G23060KN", "dp": 11 }, { "id": "G24364HL", "dp": 11 } ], "links": [ { "target": "G24364HL", "source": "G23060KN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23060KN", "source": "G09446VC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24366XJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G88948CY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G24366XJ", "dp": 11 } ], "links": [ { "target": "G24366XJ", "source": "G88948CY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24402OX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G66098KC", "dp": 14 } ], "links": [ { "target": "G24402OX", "source": "G66098KC", "residue_affected": { "residue_id": "N37", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66098KC", "source": "G18938DW", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24413UY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 } ], "links": [ { "target": "G24413UY", "source": "G78890OB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24420RT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24465EF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G24517QL", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G16201LW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G14996IQ", "dp": 8 }, { "id": "G16201LW", "dp": 9 }, { "id": "G24517QL", "dp": 9 } ], "links": [ { "target": "G24517QL", "source": "G16201LW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16201LW", "source": "G14996IQ", "residue_affected": { "residue_id": "N224", "pubchem_name": "Fuc", "anomer": "b", "absolute": "D", "form_name": "Fucp", "full_name": "β-D-Fucp" }, "effect": "Adds β-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G14996IQ", "source": "G69411IG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24552KE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G01727PW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G24552KE", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G24585JV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04791QM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G24585JV", "dp": 9 } ], "links": [ { "target": "G24585JV", "source": "G04791QM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24599MW", "notes": [], "error": "No pathways for [G24599MW] could be generated at this time" }, { "glytoucan_ac": "G24604HV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29857RC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G24604HV", "dp": 11 } ], "links": [ { "target": "G24604HV", "source": "G29857RC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24620AI", "notes": [], "error": "No pathways for [G24620AI] could be generated at this time" }, { "glytoucan_ac": "G24630CF", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G45664QZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 }, { "id": "G45664QZ", "dp": 13 }, { "id": "G24630CF", "dp": 13 } ], "links": [ { "target": "G24630CF", "source": "G45664QZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45664QZ", "source": "G81432SH", "residue_affected": { "residue_id": "N216", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24635ZS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G24635ZS] could be generated at this time" }, { "glytoucan_ac": "G24657IT", "notes": [], "error": "No pathways for [G24657IT] could be generated at this time" }, { "glytoucan_ac": "G24668UI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28550OD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G28550OD", "dp": 9 }, { "id": "G24668UI", "dp": 9 } ], "links": [ { "target": "G24668UI", "source": "G28550OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28550OD", "source": "G12398HZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24674CB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93060PS]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G93060PS", "dp": 9 }, { "id": "G24674CB", "dp": 9 } ], "links": [ { "target": "G24674CB", "source": "G93060PS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93060PS", "source": "G08520NM", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24705DL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G73759SD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G96963QG", "dp": 12 }, { "id": "G73759SD", "dp": 13 }, { "id": "G24705DL", "dp": 13 } ], "links": [ { "target": "G24705DL", "source": "G73759SD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73759SD", "source": "G96963QG", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24748QU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G24748QU] could be generated at this time" }, { "glytoucan_ac": "G24752UA", "notes": [], "error": "No pathways for [G24752UA] could be generated at this time" }, { "glytoucan_ac": "G24758NZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31220IW]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G30588SI", "dp": 9 }, { "id": "G32319IP", "dp": 10 }, { "id": "G31220IW", "dp": 11 }, { "id": "G24758NZ", "dp": 11 } ], "links": [ { "target": "G24758NZ", "source": "G31220IW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31220IW", "source": "G32319IP", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32319IP", "source": "G30588SI", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G30588SI", "source": "G08520NM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24766QM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79578JB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G24766QM", "dp": 12 } ], "links": [ { "target": "G24766QM", "source": "G79578JB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24767EG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G78661LW", "dp": 11 } ], "links": [ { "target": "G24767EG", "source": "G78661LW", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78661LW", "source": "G32201IL", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24769QK", "notes": [], "error": "No pathways for [G24769QK] could be generated at this time" }, { "glytoucan_ac": "G24791UN", "notes": [], "error": "No pathways for [G24791UN] could be generated at this time" }, { "glytoucan_ac": "G24796HF", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G12504XV", "dp": 9 } ], "links": [ { "target": "G24796HF", "source": "G12504XV", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12504XV", "source": "G08520NM", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G24797UH", "notes": [], "error": "No pathways for [G24797UH] could be generated at this time" }, { "glytoucan_ac": "G24811FP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G80147LG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G80147LG", "dp": 10 }, { "id": "G24811FP", "dp": 10 } ], "links": [ { "target": "G24811FP", "source": "G80147LG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80147LG", "source": "G27919IH", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24812WY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G05151WT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G05151WT", "dp": 12 }, { "id": "G24812WY", "dp": 12 } ], "links": [ { "target": "G24812WY", "source": "G05151WT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G05151WT", "source": "G59877NF", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24816DA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49305IN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 }, { "id": "G49305IN", "dp": 18 }, { "id": "G24816DA", "dp": 18 } ], "links": [ { "target": "G24816DA", "source": "G49305IN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49305IN", "source": "G86696LV", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24870CO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G79344MI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 }, { "id": "G24870CO", "dp": 12 } ], "links": [ { "target": "G24870CO", "source": "G79344MI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24875YE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G24875YE] could be generated at this time" }, { "glytoucan_ac": "G24888ZY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G24920KE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 } ], "links": [ { "target": "G24920KE", "source": "G57466QX", "residue_affected": { "residue_id": "N130", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24936MG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G97895RK", "dp": 13 } ], "links": [ { "target": "G24936MG", "source": "G97895RK", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G97895RK", "source": "G79578JB", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G24984RR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G24984RR] could be generated at this time" }, { "glytoucan_ac": "G24987DS", "notes": [], "error": "No pathways for [G24987DS] could be generated at this time" }, { "glytoucan_ac": "G24994OK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G24994OK", "source": "G07483YN", "residue_affected": { "residue_id": "N275", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25000QN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30404XZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 }, { "id": "G53000RQ", "dp": 11 }, { "id": "G38951VC", "dp": 12 }, { "id": "G30404XZ", "dp": 13 }, { "id": "G25000QN", "dp": 13 } ], "links": [ { "target": "G25000QN", "source": "G30404XZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30404XZ", "source": "G38951VC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G38951VC", "source": "G53000RQ", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53000RQ", "source": "G12740VA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25096GQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26080SE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G25096GQ", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G25097RR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 } ], "links": [ { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25132GJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G36523TZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G36523TZ", "dp": 12 }, { "id": "G25132GJ", "dp": 12 } ], "links": [ { "target": "G25132GJ", "source": "G36523TZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36523TZ", "source": "G29857RC", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25140TA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 } ], "links": [ { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25142NH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25142NH] could be generated at this time" }, { "glytoucan_ac": "G25162JS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G69411IG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G25162JS", "dp": 7 } ], "links": [ { "target": "G25162JS", "source": "G69411IG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25173WC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25173WC] could be generated at this time" }, { "glytoucan_ac": "G25224QY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G21756MV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G25224QY", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G25280VW", "notes": [], "error": "No pathways for [G25280VW] could be generated at this time" }, { "glytoucan_ac": "G25325YE", "notes": [], "error": "No pathways for [G25325YE] could be generated at this time" }, { "glytoucan_ac": "G25326BM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 } ], "links": [ { "target": "G25326BM", "source": "G89993FE", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25328BM", "notes": [], "error": "No pathways for [G25328BM] could be generated at this time" }, { "glytoucan_ac": "G25350TT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G59361OW", "dp": 11 } ], "links": [ { "target": "G25350TT", "source": "G59361OW", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59361OW", "source": "G44946WH", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25392ZR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25392ZR] could be generated at this time" }, { "glytoucan_ac": "G25406HP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25406HP] could be generated at this time" }, { "glytoucan_ac": "G25407RZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 } ], "links": [ { "target": "G25407RZ", "source": "G65597BI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25423CA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G32659RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G32659RY", "dp": 12 }, { "id": "G25423CA", "dp": 12 } ], "links": [ { "target": "G25423CA", "source": "G32659RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32659RY", "source": "G59877NF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25426CZ", "notes": [], "error": "No pathways for [G25426CZ] could be generated at this time" }, { "glytoucan_ac": "G25429RR", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G32611KT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G32611KT", "dp": 8 }, { "id": "G25429RR", "dp": 8 } ], "links": [ { "target": "G25429RR", "source": "G32611KT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32611KT", "source": "G39213VZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25457IZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G01935FK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01935FK", "dp": 10 }, { "id": "G25457IZ", "dp": 10 } ], "links": [ { "target": "G25457IZ", "source": "G01935FK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01935FK", "source": "G36191CD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25460BQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42686NQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G42686NQ", "dp": 14 }, { "id": "G25460BQ", "dp": 14 } ], "links": [ { "target": "G25460BQ", "source": "G42686NQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G42686NQ", "source": "G19726AG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25463XU", "notes": [], "error": "No pathways for [G25463XU] could be generated at this time" }, { "glytoucan_ac": "G25471TG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25471TG] could be generated at this time" }, { "glytoucan_ac": "G25471TR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G25471TR", "source": "G91365ZQ", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25495SR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G70374KJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G70374KJ", "dp": 11 }, { "id": "G25495SR", "dp": 11 } ], "links": [ { "target": "G25495SR", "source": "G70374KJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70374KJ", "source": "G88417ED", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25497SH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 } ], "links": [ { "target": "G25497SH", "source": "G43299SD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25505NO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 }, { "id": "G80986RU", "dp": 13 } ], "links": [ { "target": "G25505NO", "source": "G80986RU", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G80986RU", "source": "G81432SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds 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"residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25505UF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 } ], "links": [ { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25520XG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 } ], "links": [ { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25596NP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 }, { "id": "G01010HW", "dp": 9 } ], "links": [ { "target": "G25596NP", "source": "G01010HW", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25612NR", "notes": [], "error": "No pathways for [G25612NR] could be generated at this time" }, { "glytoucan_ac": "G25632TA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97947UQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G14047PA", "dp": 11 }, { "id": "G97947UQ", "dp": 12 }, { "id": "G25632TA", "dp": 12 } ], "links": [ { "target": "G25632TA", "source": "G97947UQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G97947UQ", "source": "G14047PA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G14047PA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25640AW", "notes": [], "error": "No pathways for [G25640AW] could be generated at this time" }, { "glytoucan_ac": "G25700EP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25700EP] could be generated at this time" }, { "glytoucan_ac": "G25731WL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25731WL] could be generated at this time" }, { "glytoucan_ac": "G25744PP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10209QU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G25744PP", "dp": 8 } ], "links": [ { "target": "G25744PP", "source": "G10209QU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25757VW", "notes": [], "error": "No pathways for [G25757VW] could be generated at this time" }, { "glytoucan_ac": "G25787HL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G02290KA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G02290KA", "dp": 10 }, { "id": "G25787HL", "dp": 10 } ], "links": [ { "target": "G25787HL", "source": "G02290KA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02290KA", "source": "G20030CU", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25835MT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 } ], "links": [ { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25853OY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76190UX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G25853OY", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G25886YT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G25890BU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G02025MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G25890BU", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G25902AL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45209NR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G45209NR", "dp": 15 }, { "id": "G25902AL", "dp": 15 } ], "links": [ { "target": "G25902AL", "source": "G45209NR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45209NR", "source": "G91905FJ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G25926OL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G25926OL] could be generated at this time" }, { "glytoucan_ac": "G25984CA", "notes": [], "error": "No pathways for [G25984CA] could be generated at this time" }, { "glytoucan_ac": "G26018HD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 } ], "links": [ { "target": "G26018HD", "source": "G90870DG", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26068PU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71906BW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G26068PU", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G26069FK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G26072HQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G18157KC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G26072HQ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G26080SE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G26080SE] could be generated at this time" }, { "glytoucan_ac": "G26150FI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G37046CZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G26150FI", "dp": 11 } ], "links": [ { "target": "G26150FI", "source": "G37046CZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26160AS", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G85768QF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G26160AS", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G26179TW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39377DE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G39377DE", "dp": 11 }, { "id": "G26179TW", "dp": 11 } ], "links": [ { "target": "G26179TW", "source": "G39377DE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39377DE", "source": "G09921WG", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26182BM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26206DX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52336LJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G52336LJ", "dp": 12 }, { "id": "G26206DX", "dp": 12 } ], "links": [ { "target": "G26206DX", "source": "G52336LJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52336LJ", "source": "G30302VM", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26215AL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49827WK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 }, { "id": "G49827WK", "dp": 11 }, { "id": "G26215AL", "dp": 11 } ], "links": [ { "target": "G26215AL", "source": "G49827WK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49827WK", "source": "G09446VC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26255AN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G26274XD", "dp": 11 } ], "links": [ { "target": "G26255AN", "source": "G26274XD", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G26274XD", "source": "G08187GM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26264SQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G42028DN", "dp": 11 } ], "links": [ { "target": "G26264SQ", "source": "G42028DN", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G42028DN", "source": "G09921WG", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26274XD", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 } ], "links": [ { "target": "G26274XD", "source": "G08187GM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26275JI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G09446VC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 }, { "id": "G26275JI", "dp": 10 } ], "links": [ { "target": "G26275JI", "source": "G09446VC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26295XE", "notes": [], "error": "No pathways for [G26295XE] could be generated at this time" }, { "glytoucan_ac": "G26298FT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G26298FT] could be generated at this time" }, { "glytoucan_ac": "G26299SM", "notes": [], "error": "No pathways for [G26299SM] could be generated at this time" }, { "glytoucan_ac": "G26320VO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G26320VO", "source": "G58667NI", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26347KH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G88127MB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G26347KH", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G26391HA", "notes": [], "error": "No pathways for [G26391HA] could be generated at this time" }, { "glytoucan_ac": "G26394UA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08242BT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 }, { "id": "G08242BT", "dp": 12 }, { "id": "G26394UA", "dp": 12 } ], "links": [ { "target": "G26394UA", "source": "G08242BT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08242BT", "source": "G26949IX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26474XX", "notes": [], "error": "No pathways for [G26474XX] could be generated at this time" }, { "glytoucan_ac": "G26508HK", "notes": [], "error": "No pathways for [G26508HK] could be generated at this time" }, { "glytoucan_ac": "G26534TO", "notes": [], "error": "No pathways for [G26534TO] could be generated at this time" }, { "glytoucan_ac": "G26537DD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G85106DS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G26537DD", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G26629TM", "notes": [], "error": "No pathways for [G26629TM] could be generated at this time" }, { "glytoucan_ac": "G26640MK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85180ML]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G85180ML", "dp": 10 }, { "id": "G26640MK", "dp": 10 } ], "links": [ { "target": "G26640MK", "source": "G85180ML", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85180ML", "source": "G96063MG", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26664GH", "notes": [], "error": "No pathways for [G26664GH] could be generated at this time" }, { "glytoucan_ac": "G26703BH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G26709HU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G26713RV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G16600BL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G26713RV", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G26730QM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86377SM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G26730QM", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G26756UI", "notes": [], "error": "No pathways for [G26756UI] could be generated at this time" }, { "glytoucan_ac": "G26756VT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 } ], "links": [ { "target": "G26756VT", "source": "G08863NS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26762AY", "notes": [], "error": "No pathways for [G26762AY] could be generated at this time" }, { "glytoucan_ac": "G26795PW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G11929CD", "dp": 10 } ], "links": [ { "target": "G26795PW", "source": "G11929CD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G11929CD", "source": "G09782JM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26800YB", "notes": [], "error": "No pathways for [G26800YB] could be generated at this time" }, { "glytoucan_ac": "G26844MI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G26844MI] could be generated at this time" }, { "glytoucan_ac": "G26877LE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 }, { "id": "G66572SF", "dp": 13 } ], "links": [ { "target": "G26877LE", "source": "G66572SF", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G66572SF", "source": "G48658PB", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26877ST", "notes": [], "error": "No pathways for [G26877ST] could be generated at this time" }, { "glytoucan_ac": "G26881SV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G26881SV] could be generated at this time" }, { "glytoucan_ac": "G26892SG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G26897XI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 } ], "links": [ { "target": "G26897XI", "source": "G06969ZX", "residue_affected": { "residue_id": "N299", "pubchem_name": "Fuc", "anomer": "b", "absolute": "L", "form_name": "Fucp", "full_name": "β-L-Fucp" }, "effect": "Adds β-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26935KA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G26935KA] could be generated at this time" }, { "glytoucan_ac": "G26939ZY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G26939ZY", "source": "G39213VZ", "residue_affected": { "residue_id": "N306", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26949IX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G26983WI", "notes": [], "error": "No pathways for [G26983WI] could be generated at this time" }, { "glytoucan_ac": "G26985TZ", "notes": [], "error": "No pathways for [G26985TZ] could be generated at this time" }, { "glytoucan_ac": "G27040MJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97765TT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G97765TT", "dp": 12 }, { "id": "G27040MJ", "dp": 12 } ], "links": [ { "target": "G27040MJ", "source": "G97765TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G97765TT", "source": "G18219CJ", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27048LG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G33742YO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G33742YO", "dp": 9 }, { "id": "G27048LG", "dp": 9 } ], "links": [ { "target": "G27048LG", "source": "G33742YO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27067YD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76294TY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G27067YD", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G27092SD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G90870DG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G27092SD", "dp": 11 } ], "links": [ { "target": "G27092SD", "source": "G90870DG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27119UQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G22728HO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G54584ER", "dp": 14 }, { "id": "G22728HO", "dp": 15 }, { "id": "G27119UQ", "dp": 15 } ], "links": [ { "target": "G27119UQ", "source": "G22728HO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G22728HO", "source": "G54584ER", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G54584ER", "source": "G18938DW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27123NH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27148YF", "notes": [], "error": "No pathways for [G27148YF] could be generated at this time" }, { "glytoucan_ac": "G27149SR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G45209NR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G45209NR", "dp": 15 }, { "id": "G27149SR", "dp": 15 } ], "links": [ { "target": "G27149SR", "source": "G45209NR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45209NR", "source": "G91905FJ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27168SG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89099NM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G89099NM", "dp": 10 }, { "id": "G27168SG", "dp": 10 } ], "links": [ { "target": "G27168SG", "source": "G89099NM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89099NM", "source": "G20966TZ", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27170BX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G07995VK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 }, { "id": "G27170BX", "dp": 10 } ], "links": [ { "target": "G27170BX", "source": "G07995VK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27170NH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G04791QM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G27170NH", "dp": 9 } ], "links": [ { "target": "G27170NH", "source": "G04791QM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27171ZS", "notes": [], "error": "No pathways for [G27171ZS] could be generated at this time" }, { "glytoucan_ac": "G27188NC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G27188NC", "source": "G07483YN", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27223CU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 } ], "links": [ { "target": "G27223CU", "source": "G82252QI", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27263RW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G27273FD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G27273FD] could be generated at this time" }, { "glytoucan_ac": "G27281KS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G27281KS] could be generated at this time" }, { "glytoucan_ac": "G27293OK", "notes": [], "error": "No pathways for [G27293OK] could be generated at this time" }, { "glytoucan_ac": "G27314YB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G07483YN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G27314YB", "dp": 7 } ], "links": [ { "target": "G27314YB", "source": "G07483YN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27316ME", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17437BX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G17437BX", "dp": 14 }, { "id": "G27316ME", "dp": 14 } ], "links": [ { "target": "G27316ME", "source": "G17437BX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17437BX", "source": "G92359VA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27385LP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G33608TH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G27385LP", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G27389SR", "notes": [], "error": "No pathways for [G27389SR] could be generated at this time" }, { "glytoucan_ac": "G27419MQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99356PZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G99356PZ", "dp": 9 }, { "id": "G27419MQ", "dp": 9 } ], "links": [ { "target": "G27419MQ", "source": "G99356PZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99356PZ", "source": "G12398HZ", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27421EI", "notes": [], "error": "No pathways for [G27421EI] could be generated at this time" }, { "glytoucan_ac": "G27432KC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G27432KC] could be generated at this time" }, { "glytoucan_ac": "G27456PF", "notes": [], "error": "No pathways for [G27456PF] could be generated at this time" }, { "glytoucan_ac": "G27461ST", "notes": [], "error": "No pathways for [G27461ST] could be generated at this time" }, { "glytoucan_ac": "G27495UM", "notes": [], "error": "No pathways for [G27495UM] could be generated at this time" }, { "glytoucan_ac": "G27516AE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G27546OZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 } ], "links": [ { "target": "G27546OZ", "source": "G75049FP", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27571QK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38955TH]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G40806JH", "dp": 11 }, { "id": "G38955TH", "dp": 12 }, { "id": "G27571QK", "dp": 12 } ], "links": [ { "target": "G27571QK", "source": "G38955TH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38955TH", "source": "G40806JH", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27587OB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51050LD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G27587OB", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G27658GQ", "notes": [], "error": "No pathways for [G27658GQ] could be generated at this time" }, { "glytoucan_ac": "G27669RW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59361OW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G59361OW", "dp": 11 }, { "id": "G27669RW", "dp": 11 } ], "links": [ { "target": "G27669RW", "source": "G59361OW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59361OW", "source": "G44946WH", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27692UI", "notes": [], "error": "No pathways for [G27692UI] could be generated at this time" }, { "glytoucan_ac": "G27776PG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 } ], "links": [ { "target": "G27776PG", "source": "G20956ZK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27783SY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G27783SY] could be generated at this time" }, { "glytoucan_ac": "G27802LV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G27802LV", "source": "G36191CD", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27844UM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G27844UM] could be generated at this time" }, { "glytoucan_ac": "G27874QL", "notes": [], "error": "No pathways for [G27874QL] could be generated at this time" }, { "glytoucan_ac": "G27919IH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 } ], "links": [ { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27929ZE", "notes": [], "error": "No pathways for [G27929ZE] could be generated at this time" }, { "glytoucan_ac": "G27939KO", "notes": [], "error": "No pathways for [G27939KO] could be generated at this time" }, { "glytoucan_ac": "G27946NT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 } ], "links": [ { "target": "G27946NT", "source": "G24420RT", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G27957OQ", "notes": [], "error": "No pathways for [G27957OQ] could be generated at this time" }, { "glytoucan_ac": "G27992WA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66016NA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G27992WA", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G27995KI", "notes": [], "error": "No pathways for [G27995KI] could be generated at this time" }, { "glytoucan_ac": "G28106CM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 } ], "links": [ { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28127QJ", "notes": [], "error": "No pathways for [G28127QJ] could be generated at this time" }, { "glytoucan_ac": "G28128KH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G60103QI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G54611ZT", "dp": 11 }, { "id": "G60103QI", "dp": 12 }, { "id": "G28128KH", "dp": 12 } ], "links": [ { "target": "G28128KH", "source": "G60103QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60103QI", "source": "G54611ZT", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28144EE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G74928QN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 }, { "id": "G74928QN", "dp": 14 }, { "id": "G28144EE", "dp": 14 } ], "links": [ { "target": "G28144EE", "source": "G74928QN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74928QN", "source": "G29449JO", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28218GE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G17689DH", "dp": 12 } ], "links": [ { "target": "G28218GE", "source": "G17689DH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28231AL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 }, { "id": "G95404EQ", "dp": 17 }, { "id": "G31004HS", "dp": 18 } ], "links": [ { "target": "G28231AL", "source": "G31004HS", "residue_affected": { "residue_id": "N362", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G31004HS", "source": "G95404EQ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28274SP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G16155TD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G16155TD", "dp": 13 }, { "id": "G28274SP", "dp": 13 } ], "links": [ { "target": "G28274SP", "source": "G16155TD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16155TD", "source": "G01669LU", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28281DE", "notes": [], "error": "No pathways for [G28281DE] could be generated at this time" }, { "glytoucan_ac": "G28298VW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 } ], "links": [ { "target": "G28298VW", "source": "G48658PB", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28327SH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G28330DZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23616ZX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 }, { "id": "G28330DZ", "dp": 14 } ], "links": [ { "target": "G28330DZ", "source": "G23616ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28355VE", "notes": [], "error": "No pathways for [G28355VE] could be generated at this time" }, { "glytoucan_ac": "G28355WG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84064AY]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G84064AY", "dp": 9 }, { "id": "G28355WG", "dp": 9 } ], "links": [ { "target": "G28355WG", "source": "G84064AY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84064AY", "source": "G08520NM", "residue_affected": { "residue_id": "N365", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G28436VD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G28449NP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G92940AF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 }, { "id": "G92940AF", "dp": 14 }, { "id": "G28449NP", "dp": 14 } ], "links": [ { "target": "G28449NP", "source": "G92940AF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92940AF", "source": "G37597FW", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28459KM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25505UF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G25505UF", "dp": 14 }, { "id": "G28459KM", "dp": 14 } ], "links": [ { "target": "G28459KM", "source": "G25505UF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28478RU", "notes": [], "error": "No pathways for [G28478RU] could be generated at this time" }, { "glytoucan_ac": "G28550OD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G28550OD", "source": "G12398HZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28558PZ", "notes": [], "error": "No pathways for [G28558PZ] could be generated at this time" }, { "glytoucan_ac": "G28562FF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G42731RJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G28562FF", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G28593TO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04829RO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 }, { "id": "G01010HW", "dp": 9 }, { "id": "G04829RO", "dp": 10 }, { "id": "G28593TO", "dp": 10 } ], "links": [ { "target": "G28593TO", "source": "G04829RO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04829RO", "source": "G01010HW", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28615QI", "notes": [], "error": "No pathways for [G28615QI] could be generated at this time" }, { "glytoucan_ac": "G28654UV", "notes": [], "error": "No pathways for [G28654UV] could be generated at this time" }, { "glytoucan_ac": "G28659UB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74645FT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G28659UB", "dp": 12 } ], "links": [ { "target": "G28659UB", "source": "G74645FT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28663KH", "notes": [], "error": "No pathways for [G28663KH] could be generated at this time" }, { "glytoucan_ac": "G28678TH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39408YK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G39408YK", "dp": 12 }, { "id": "G28678TH", "dp": 12 } ], "links": [ { "target": "G28678TH", "source": "G39408YK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39408YK", "source": "G25520XG", "residue_affected": { "residue_id": "N368", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28695FK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G94610SC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G28695FK", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G28707FT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G03948VT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G28707FT", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G28720MP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32611KT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G32611KT", "dp": 8 }, { "id": "G28720MP", "dp": 8 } ], "links": [ { "target": "G28720MP", "source": "G32611KT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32611KT", "source": "G39213VZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28723UT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 } ], "links": [ { "target": "G28723UT", "source": "G87073UP", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28747XN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G96921ZU", "dp": 12 } ], "links": [ { "target": "G28747XN", "source": "G96921ZU", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96921ZU", "source": "G11041DA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28826SH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28846QB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 }, { "id": "G42097JO", "dp": 14 } ], "links": [ { "target": "G28846QB", "source": "G42097JO", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G42097JO", "source": "G85085MS", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28882QV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07015TW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G10664FL", "dp": 10 }, { "id": "G07015TW", "dp": 11 }, { "id": "G28882QV", "dp": 11 } ], "links": [ { "target": "G28882QV", "source": "G07015TW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07015TW", "source": "G10664FL", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10664FL", "source": "G45262QY", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28896CL", "notes": [], "error": "No pathways for [G28896CL] could be generated at this time" }, { "glytoucan_ac": "G28948UC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 } ], "links": [ { "target": "G28948UC", "source": "G10691MJ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28957FB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 } ], "links": [ { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28959FS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G43694RQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G28959FS", "dp": 10 } ], "links": [ { "target": "G28959FS", "source": "G43694RQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G28962GO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G63166WT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G63166WT", "dp": 12 }, { "id": "G28962GO", "dp": 12 } ], "links": [ { "target": "G28962GO", "source": "G63166WT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63166WT", "source": "G30302VM", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29005BV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G47566FL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G47566FL", "dp": 8 }, { "id": "G29005BV", "dp": 8 } ], "links": [ { "target": "G29005BV", "source": "G47566FL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47566FL", "source": "G07483YN", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29011JC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29024OJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27919IH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G29024OJ", "dp": 9 } ], "links": [ { "target": "G29024OJ", "source": "G27919IH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29026MS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 } ], "links": [ { "target": "G29026MS", "source": "G59877NF", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29032AL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23709VK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G82357WL", "dp": 11 }, { "id": "G23709VK", "dp": 12 }, { "id": "G29032AL", "dp": 12 } ], "links": [ { "target": "G29032AL", "source": "G23709VK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23709VK", "source": "G82357WL", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G82357WL", "source": "G28826SH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29056SI", "notes": [], "error": "No pathways for [G29056SI] could be generated at this time" }, { "glytoucan_ac": "G29078QN", "notes": [], "error": "No pathways for [G29078QN] could be generated at this time" }, { "glytoucan_ac": "G29109PM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82320NZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G29109PM", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G29112GC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G29112GC", "source": "G20030CU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29130SY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G29130SY] could be generated at this time" }, { "glytoucan_ac": "G29147GG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91208VE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G91208VE", "dp": 9 }, { "id": "G29147GG", "dp": 9 } ], "links": [ { "target": "G29147GG", "source": "G91208VE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29159BL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G29159BL", "source": "G12398HZ", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29197GH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G29197GH", "source": "G10219AA", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29248WR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46470AD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 }, { "id": "G46470AD", "dp": 11 }, { "id": "G29248WR", "dp": 11 } ], "links": [ { "target": "G29248WR", "source": "G46470AD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46470AD", "source": "G01856RL", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29288DT", "notes": [], "error": "No pathways for [G29288DT] could be generated at this time" }, { "glytoucan_ac": "G29290EB", "notes": [], "error": "No pathways for [G29290EB] could be generated at this time" }, { "glytoucan_ac": "G29377XJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 } ], "links": [ { "target": "G29377XJ", "source": "G63585HN", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29396PC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G78155FK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 }, { "id": "G29396PC", "dp": 10 } ], "links": [ { "target": "G29396PC", "source": "G78155FK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29434RB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29441UP", "notes": [], "error": "No pathways for [G29441UP] could be generated at this time" }, { "glytoucan_ac": "G29443MC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G29445ZK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G29445ZK] could be generated at this time" }, { "glytoucan_ac": "G29449JO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 } ], "links": [ { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29461HI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30302VM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G29461HI", "dp": 11 } ], "links": [ { "target": "G29461HI", "source": "G30302VM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29467ZM", "notes": [], "error": "No pathways for [G29467ZM] could be generated at this time" }, { "glytoucan_ac": "G29492IF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29519AS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G32065BG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G29519AS", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G29574TI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G26881SV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G29574TI", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G29617QF", "notes": [], "error": "No pathways for [G29617QF] could be generated at this time" }, { "glytoucan_ac": "G29628IK", "notes": [], "error": "No pathways for [G29628IK] could be generated at this time" }, { "glytoucan_ac": "G29633ZY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16341ZC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G57943ZV", "dp": 11 }, { "id": "G16341ZC", "dp": 12 }, { "id": "G29633ZY", "dp": 12 } ], "links": [ { "target": "G29633ZY", "source": "G16341ZC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16341ZC", "source": "G57943ZV", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G57943ZV", "source": "G52934AK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29676WX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G06216UH", "dp": 10 }, { "id": "G49743VF", "dp": 11 } ], "links": [ { "target": "G29676WX", "source": "G49743VF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G49743VF", "source": "G06216UH", "residue_affected": { "residue_id": "N470", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29680KY", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G17213JF", "dp": 11 } ], "links": [ { "target": "G29680KY", "source": "G17213JF", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29695SR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G68283NG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G29695SR", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G29706UC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G29706UC", "source": "G58667NI", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29713JZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G40358EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G40358EZ", "dp": 11 }, { "id": "G29713JZ", "dp": 11 } ], "links": [ { "target": "G29713JZ", "source": "G40358EZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40358EZ", "source": "G00176HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29764SO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14428PM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G29764SO", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G29797YX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 }, { "id": "G89181JW", "dp": 11 } ], "links": [ { "target": "G29797YX", "source": "G89181JW", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G89181JW", "source": "G03445UI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29799SM", "notes": [], "error": "No pathways for [G29799SM] could be generated at this time" }, { "glytoucan_ac": "G29803MG", "notes": [], "error": "No pathways for [G29803MG] could be generated at this time" }, { "glytoucan_ac": "G29849KU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G23782KP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G29849KU", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G29850BY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14520ZO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G29850BY", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G29857PJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G29857PJ] could be generated at this time" }, { "glytoucan_ac": "G29857RC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 } ], "links": [ { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29870RM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G66866LE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 }, { "id": "G29870RM", "dp": 10 } ], "links": [ { "target": "G29870RM", "source": "G66866LE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29884LW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20096RP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G20096RP", "dp": 12 }, { "id": "G29884LW", "dp": 12 } ], "links": [ { "target": "G29884LW", "source": "G20096RP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20096RP", "source": "G25520XG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29897FU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G47963XB", "dp": 14 } ], "links": [ { "target": "G29897FU", "source": "G47963XB", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G47963XB", "source": "G66282NU", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29905OR", "notes": [], "error": "No pathways for [G29905OR] could be generated at this time" }, { "glytoucan_ac": "G29931YE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G60941RE", "dp": 13 } ], "links": [ { "target": "G29931YE", "source": "G60941RE", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60941RE", "source": "G75185NU", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29948BS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G69912LP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G41720HN", "dp": 8 }, { "id": "G69912LP", "dp": 9 }, { "id": "G29948BS", "dp": 9 } ], "links": [ { "target": "G29948BS", "source": "G69912LP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69912LP", "source": "G41720HN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G41720HN", "source": "G07483YN", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G29955AF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G29955AF] could be generated at this time" }, { "glytoucan_ac": "G29972ZX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G88380UG", "dp": 8 } ], "links": [ { "target": "G29972ZX", "source": "G88380UG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88380UG", "source": "G39213VZ", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30007CD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 }, { "id": "G25407RZ", "dp": 11 } ], "links": [ { "target": "G30007CD", "source": "G25407RZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G25407RZ", "source": "G65597BI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30015VH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G72411HX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G30015VH", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G30035MO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G77252PU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 }, { "id": "G30035MO", "dp": 11 } ], "links": [ { "target": "G30035MO", "source": "G77252PU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30048YR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 }, { "id": "G66190PM", "dp": 11 } ], "links": [ { "target": "G30048YR", "source": "G66190PM", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G66190PM", "source": "G78155FK", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30060ZO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G30062BR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41797PU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G30062BR", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G30085SO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G30085SO] could be generated at this time" }, { "glytoucan_ac": "G30109UP", "notes": [], "error": "No pathways for [G30109UP] could be generated at this time" }, { "glytoucan_ac": "G30115SP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10691MJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G30115SP", "dp": 11 } ], "links": [ { "target": "G30115SP", "source": "G10691MJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30140II", "notes": [], "error": "No pathways for [G30140II] could be generated at this time" }, { "glytoucan_ac": "G30159WR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 } ], "links": [ { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30293NE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G30293NE] could be generated at this time" }, { "glytoucan_ac": "G30302VM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30309QX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G71013KY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G30309QX", "dp": 10 } ], "links": [ { "target": "G30309QX", "source": "G71013KY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30314VR", "notes": [], "error": "No pathways for [G30314VR] could be generated at this time" }, { "glytoucan_ac": "G30319FW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G46712PI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G46712PI", "dp": 11 }, { "id": "G30319FW", "dp": 11 } ], "links": [ { "target": "G30319FW", "source": "G46712PI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46712PI", "source": "G00176HZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30347FC", "notes": [], "error": "No pathways for [G30347FC] could be generated at this time" }, { "glytoucan_ac": "G30372WK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G30404XZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 }, { "id": "G53000RQ", "dp": 11 }, { "id": "G38951VC", "dp": 12 } ], "links": [ { "target": "G30404XZ", "source": "G38951VC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G38951VC", "source": "G53000RQ", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53000RQ", "source": "G12740VA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30416OM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47566FL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G47566FL", "dp": 8 }, { "id": "G30416OM", "dp": 8 } ], "links": [ { "target": "G30416OM", "source": "G47566FL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47566FL", "source": "G07483YN", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30437YI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G30437YI] could be generated at this time" }, { "glytoucan_ac": "G30447NS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43088GK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G30447NS", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G30460NZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30483FB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G30483FB] could be generated at this time" }, { "glytoucan_ac": "G30505TQ", "notes": [], "error": "No pathways for [G30505TQ] could be generated at this time" }, { "glytoucan_ac": "G30514JJ", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G30514JJ] could be generated at this time" }, { "glytoucan_ac": "G30517YN", "notes": [], "error": "No pathways for [G30517YN] could be generated at this time" }, { "glytoucan_ac": "G30529FG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82779CI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G30529FG", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G30542PN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G73418FX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G00743WU", "dp": 11 }, { "id": "G73418FX", "dp": 12 }, { "id": "G30542PN", "dp": 12 } ], "links": [ { "target": "G30542PN", "source": "G73418FX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73418FX", "source": "G00743WU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30547LG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G61553DD", "dp": 9 } ], "links": [ { "target": "G30547LG", "source": "G61553DD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61553DD", "source": "G29011JC", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30553WH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 } ], "links": [ { "target": "G30553WH", "source": "G20956ZK", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30569KZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G04185VX", "dp": 10 } ], "links": [ { "target": "G30569KZ", "source": "G04185VX", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04185VX", "source": "G36191CD", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30585MP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10209QU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G30585MP", "dp": 8 } ], "links": [ { "target": "G30585MP", "source": "G10209QU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30588SI", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G30588SI", "source": "G08520NM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30618VC", "notes": [], "error": "No pathways for [G30618VC] could be generated at this time" }, { "glytoucan_ac": "G30627OI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G30627OI] could be generated at this time" }, { "glytoucan_ac": "G30651IU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 } ], "links": [ { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30673AC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42548XF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G42548XF", "dp": 7 }, { "id": "G30673AC", "dp": 7 } ], "links": [ { "target": "G30673AC", "source": "G42548XF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G42548XF", "source": "G61751GZ", "residue_affected": { "residue_id": "N204", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] } ] } , { "glytoucan_ac": "G30687DL", "notes": [], "error": "No pathways for [G30687DL] could be generated at this time" }, { "glytoucan_ac": "G30690LP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G30690LP", "source": "G18938DW", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30694RX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G30694RX] could be generated at this time" }, { "glytoucan_ac": "G30723RE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 } ], "links": [ { "target": "G30723RE", "source": "G68937TM", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30762QR", "notes": [], "error": "No pathways for [G30762QR] could be generated at this time" }, { "glytoucan_ac": "G30844CL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 } ], "links": [ { "target": "G30844CL", "source": "G24420RT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30857WQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25350TT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G59361OW", "dp": 11 }, { "id": "G25350TT", "dp": 12 }, { "id": "G30857WQ", "dp": 12 } ], "links": [ { "target": "G30857WQ", "source": "G25350TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25350TT", "source": "G59361OW", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59361OW", "source": "G44946WH", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30880RA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G30880RA] could be generated at this time" }, { "glytoucan_ac": "G30901GC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 } ], "links": [ { "target": "G30901GC", "source": "G79348ZY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30915AU", "notes": [], "error": "No pathways for [G30915AU] could be generated at this time" }, { "glytoucan_ac": "G30917DM", "notes": [], "error": "No pathways for [G30917DM] could be generated at this time" }, { "glytoucan_ac": "G30925FN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 } ], "links": [ { "target": "G30925FN", "source": "G45720CA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G30969JI", "notes": [], "error": "No pathways for [G30969JI] could be generated at this time" }, { "glytoucan_ac": "G30996QM", "notes": [], "error": "No pathways for [G30996QM] could be generated at this time" }, { "glytoucan_ac": "G31004HS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 }, { "id": "G95404EQ", "dp": 17 } ], "links": [ { "target": "G31004HS", "source": "G95404EQ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31010RQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 } ], "links": [ { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31019WF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G31019WF] could be generated at this time" }, { "glytoucan_ac": "G31032XG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53504BR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G31032XG", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G31037WG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 } ], "links": [ { "target": "G31037WG", "source": "G92574YO", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31040SL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G31156QG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G75398ZA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G31156QG", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G31186LT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79803HS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 }, { "id": "G74438AB", "dp": 12 }, { "id": "G79803HS", "dp": 13 }, { "id": "G31186LT", "dp": 13 } ], "links": [ { "target": "G31186LT", "source": "G79803HS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79803HS", "source": "G74438AB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G74438AB", "source": "G34905OT", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31196DF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G09921WG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G31196DF", "dp": 10 } ], "links": [ { "target": "G31196DF", "source": "G09921WG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31213GU", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G70410NP]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G31213GU", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G31220IW", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G30588SI", "dp": 9 }, { "id": "G32319IP", "dp": 10 } ], "links": [ { "target": "G31220IW", "source": "G32319IP", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32319IP", "source": "G30588SI", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G30588SI", "source": "G08520NM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31242TK", "notes": [], "error": "No pathways for [G31242TK] could be generated at this time" }, { "glytoucan_ac": "G31294RU", "notes": [], "error": "No pathways for [G31294RU] could be generated at this time" }, { "glytoucan_ac": "G31337GK", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G71407IE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G71407IE", "dp": 8 }, { "id": "G31337GK", "dp": 8 } ], "links": [ { "target": "G31337GK", "source": "G71407IE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71407IE", "source": "G69411IG", "residue_affected": { "residue_id": "N224", "pubchem_name": "Fuc", "anomer": "b", "absolute": "D", "form_name": "Fucp", "full_name": "β-D-Fucp" }, "effect": "Adds β-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31341PC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G38022PE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G31341PC", "dp": 14 } ], "links": [ { "target": "G31341PC", "source": "G38022PE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31373ZL", "notes": [], "error": "No pathways for [G31373ZL] could be generated at this time" }, { "glytoucan_ac": "G31387PS", "notes": [], "error": "No pathways for [G31387PS] could be generated at this time" }, { "glytoucan_ac": "G31411GR", "notes": [], "error": "No pathways for [G31411GR] could be generated at this time" }, { "glytoucan_ac": "G31416KB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41720HN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G41720HN", "dp": 8 }, { "id": "G31416KB", "dp": 8 } ], "links": [ { "target": "G31416KB", "source": "G41720HN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41720HN", "source": "G07483YN", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31421EZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G28948UC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G28948UC", "dp": 12 }, { "id": "G31421EZ", "dp": 12 } ], "links": [ { "target": "G31421EZ", "source": "G28948UC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28948UC", "source": "G10691MJ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31429YW", "notes": [], "error": "No pathways for [G31429YW] could be generated at this time" }, { "glytoucan_ac": "G31494OZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 } ], "links": [ { "target": "G31494OZ", "source": "G60564DP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31515BE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G65239SF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 }, { "id": "G65239SF", "dp": 11 }, { "id": "G31515BE", "dp": 11 } ], "links": [ { "target": "G31515BE", "source": "G65239SF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65239SF", "source": "G81923ER", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31520YP", "notes": [], "error": "No pathways for [G31520YP] could be generated at this time" }, { "glytoucan_ac": "G31531YC", "notes": [], "error": "No pathways for [G31531YC] could be generated at this time" }, { "glytoucan_ac": "G31532GK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 }, { "id": "G03895SR", "dp": 15 }, { "id": "G09118YK", "dp": 16 } ], "links": [ { "target": "G31532GK", "source": "G09118YK", "residue_affected": { "residue_id": "N108", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G09118YK", "source": "G03895SR", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G03895SR", "source": "G16150CJ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31540AF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56516KW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G31540AF", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G31555TF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 } ], "links": [ { "target": "G31555TF", "source": "G65597BI", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31559RO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G68892PJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G31559RO", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G31587OK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G44623TX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G44623TX", "dp": 12 }, { "id": "G31587OK", "dp": 12 } ], "links": [ { "target": "G31587OK", "source": "G44623TX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44623TX", "source": "G79809MM", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31604HF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G31604HF", "source": "G07483YN", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31606TH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31037WG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G31037WG", "dp": 18 }, { "id": "G31606TH", "dp": 18 } ], "links": [ { "target": "G31606TH", "source": "G31037WG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31037WG", "source": "G92574YO", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31616YD", "notes": [], "error": "No pathways for [G31616YD] could be generated at this time" }, { "glytoucan_ac": "G31627MW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49915LA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G31627MW", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G31637BB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G31637BB] could be generated at this time" }, { "glytoucan_ac": "G31642UV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G43664YB", "dp": 9 } ], "links": [ { "target": "G31642UV", "source": "G43664YB", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43664YB", "source": "G24420RT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31662BR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G97895RK", "dp": 13 } ], "links": [ { "target": "G31662BR", "source": "G97895RK", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G97895RK", "source": "G79578JB", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31668AP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G14047PA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G14047PA", "dp": 11 }, { "id": "G31668AP", "dp": 11 } ], "links": [ { "target": "G31668AP", "source": "G14047PA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14047PA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31670BC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G97093EP", "dp": 12 } ], "links": [ { "target": "G31670BC", "source": "G97093EP", "residue_affected": { "residue_id": "N246", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G97093EP", "source": "G43433FA", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31679YU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G50078RT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G50078RT", "dp": 12 }, { "id": "G31679YU", "dp": 12 } ], "links": [ { "target": "G31679YU", "source": "G50078RT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50078RT", "source": "G79809MM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31692TJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G07995VK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 }, { "id": "G31692TJ", "dp": 10 } ], "links": [ { "target": "G31692TJ", "source": "G07995VK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31720WP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G31814JO", "notes": [], "error": "No pathways for [G31814JO] could be generated at this time" }, { "glytoucan_ac": "G31822CM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57166CI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G31822CM", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G31865AG", "notes": [], "error": "No pathways for [G31865AG] could be generated at this time" }, { "glytoucan_ac": "G31943KG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G61207RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G31943KG", "dp": 9 } ], "links": [ { "target": "G31943KG", "source": "G61207RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G31991IV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G31991IV] could be generated at this time" }, { "glytoucan_ac": "G31993QW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11637WL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G31993QW", "dp": 10 } ], "links": [ { "target": "G31993QW", "source": "G11637WL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32065BG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G32065BG] could be generated at this time" }, { "glytoucan_ac": "G32079YD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G14428PM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G32079YD", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G32082KI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G32114CQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G32114CQ] could be generated at this time" }, { "glytoucan_ac": "G32116UD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 }, { "id": "G42097JO", "dp": 14 }, { "id": "G28846QB", "dp": 15 } ], "links": [ { "target": "G32116UD", "source": "G28846QB", "residue_affected": { "residue_id": "N246", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G28846QB", "source": "G42097JO", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G42097JO", "source": "G85085MS", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32149KV", "notes": [], "error": "No pathways for [G32149KV] could be generated at this time" }, { "glytoucan_ac": "G32156DB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G80661IW", "dp": 10 } ], "links": [ { "target": "G32156DB", "source": "G80661IW", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G80661IW", "source": "G46638GC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32156ZV", "notes": [], "error": "No pathways for [G32156ZV] could be generated at this time" }, { "glytoucan_ac": "G32173NW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G32173NW] could be generated at this time" }, { "glytoucan_ac": "G32190EA", "notes": [], "error": "No pathways for [G32190EA] could be generated at this time" }, { "glytoucan_ac": "G32201IL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32241HI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G43299SD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G32241HI", "dp": 9 } ], "links": [ { "target": "G32241HI", "source": "G43299SD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32283ZK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 } ], "links": [ { "target": "G32283ZK", "source": "G20956ZK", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32287FD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 } ], "links": [ { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32303JY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 } ], "links": [ { "target": "G32303JY", "source": "G81432SH", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32305RZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 } ], "links": [ { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32319IP", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G30588SI", "dp": 9 } ], "links": [ { "target": "G32319IP", "source": "G30588SI", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G30588SI", "source": "G08520NM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32324QA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G32324QA] could be generated at this time" }, { "glytoucan_ac": "G32358YV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G71957GO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G32358YV", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G32364DF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17857ZF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 }, { "id": "G57970NA", "dp": 13 }, { "id": "G17857ZF", "dp": 14 }, { "id": "G32364DF", "dp": 14 } ], "links": [ { "target": "G32364DF", "source": "G17857ZF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17857ZF", "source": "G57970NA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G57970NA", "source": "G49515VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32371XG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G36108GD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G36108GD", "dp": 11 }, { "id": "G32371XG", "dp": 11 } ], "links": [ { "target": "G32371XG", "source": "G36108GD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36108GD", "source": "G32305RZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32377GZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82234NO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G32377GZ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G32386AG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G22558JP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G32386AG", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G32461GF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 } ], "links": [ { "target": "G32461GF", "source": "G86696LV", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32483HZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G32484KU", "notes": [], "error": "No pathways for [G32484KU] could be generated at this time" }, { "glytoucan_ac": "G32510IZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G62765SF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G32510IZ", "dp": 14 } ], "links": [ { "target": "G32510IZ", "source": "G62765SF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32518YQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G32592IB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 } ], "links": [ { "target": "G32592IB", "source": "G10228OD", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32611KT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G32611KT", "source": "G39213VZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32646BW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G35655SC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G74574VX", "dp": 11 }, { "id": "G83499UD", "dp": 12 }, { "id": "G35655SC", "dp": 13 }, { "id": "G32646BW", "dp": 13 } ], "links": [ { "target": "G32646BW", "source": "G35655SC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G35655SC", "source": "G83499UD", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G83499UD", "source": "G74574VX", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74574VX", "source": "G27123NH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32659RY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 } ], "links": [ { "target": "G32659RY", "source": "G59877NF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32660GU", "notes": [], "error": "No pathways for [G32660GU] could be generated at this time" }, { "glytoucan_ac": "G32704TW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G32704TW", "source": "G12398HZ", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32744YO", "notes": [], "error": "No pathways for [G32744YO] could be generated at this time" }, { "glytoucan_ac": "G32746QI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G98559XP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G98559XP", "dp": 14 }, { "id": "G32746QI", "dp": 14 } ], "links": [ { "target": "G32746QI", "source": "G98559XP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98559XP", "source": "G18938DW", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32758HZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G96921ZU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G96921ZU", "dp": 12 }, { "id": "G32758HZ", "dp": 12 } ], "links": [ { "target": "G32758HZ", "source": "G96921ZU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96921ZU", "source": "G11041DA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32761XQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G88864RV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G32761XQ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G32779JS", "notes": [], "error": "No pathways for [G32779JS] could be generated at this time" }, { "glytoucan_ac": "G32808NL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 }, { "id": "G01923XE", "dp": 14 } ], "links": [ { "target": "G32808NL", "source": "G01923XE", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01923XE", "source": "G95898GD", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32829EU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G92681HQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G98852TR", "dp": 16 }, { "id": "G92681HQ", "dp": 17 }, { "id": "G32829EU", "dp": 17 } ], "links": [ { "target": "G32829EU", "source": "G92681HQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92681HQ", "source": "G98852TR", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G98852TR", "source": "G28957FB", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32883QH", "notes": [], "error": "No pathways for [G32883QH] could be generated at this time" }, { "glytoucan_ac": "G32915BP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G58667NI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G32915BP", "dp": 9 } ], "links": [ { "target": "G32915BP", "source": "G58667NI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G32977ZV", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G32977ZV] could be generated at this time" }, { "glytoucan_ac": "G33001NX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 } ], "links": [ { "target": "G33001NX", "source": "G39089YD", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G33019PZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G31037WG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G31037WG", "dp": 18 }, { "id": "G33019PZ", "dp": 18 } ], "links": [ { "target": "G33019PZ", "source": "G31037WG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31037WG", "source": "G92574YO", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33030OB", "notes": [], "error": "No pathways for [G33030OB] could be generated at this time" }, { "glytoucan_ac": "G33052SB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98862GW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G98862GW", "dp": 13 }, { "id": "G33052SB", "dp": 13 } ], "links": [ { "target": "G33052SB", "source": "G98862GW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98862GW", "source": "G75049FP", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33066WV", "notes": [], "error": "No pathways for [G33066WV] could be generated at this time" }, { "glytoucan_ac": "G33070IY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09921WG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G33070IY", "dp": 10 } ], "links": [ { "target": "G33070IY", "source": "G09921WG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33082JZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G33082JZ] could be generated at this time" }, { "glytoucan_ac": "G33089BG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G33150PJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78956IC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G91413ZX", "dp": 15 }, { "id": "G78956IC", "dp": 16 }, { "id": "G33150PJ", "dp": 16 } ], "links": [ { "target": "G33150PJ", "source": "G78956IC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78956IC", "source": "G91413ZX", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33192XL", "notes": [], "error": "No pathways for [G33192XL] could be generated at this time" }, { "glytoucan_ac": "G33202XC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 } ], "links": [ { "target": "G33202XC", "source": "G75185NU", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33241WC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 } ], "links": [ { "target": "G33241WC", "source": "G45720CA", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33244HE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59451NL", "dp": 8 } ], "links": [ { "target": "G33244HE", "source": "G59451NL", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59451NL", "source": "G39213VZ", "residue_affected": { "residue_id": "N299", "pubchem_name": "Fuc", "anomer": "b", "absolute": "L", "form_name": "Fucp", "full_name": "β-L-Fucp" }, "effect": "Adds β-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33249PE", "notes": [], "error": "No pathways for [G33249PE] could be generated at this time" }, { "glytoucan_ac": "G33262KR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G40806JH", "dp": 11 } ], "links": [ { "target": "G33262KR", "source": "G40806JH", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33262YZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G33262YZ", "source": "G52934AK", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33264BF", "notes": [], "error": "No pathways for [G33264BF] could be generated at this time" }, { "glytoucan_ac": "G33271XM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59451NL", "dp": 8 } ], "links": [ { "target": "G33271XM", "source": "G59451NL", "residue_affected": { "residue_id": "N322", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59451NL", "source": "G39213VZ", "residue_affected": { "residue_id": "N299", "pubchem_name": "Fuc", "anomer": "b", "absolute": "L", "form_name": "Fucp", "full_name": "β-L-Fucp" }, "effect": "Adds β-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33275DG", "notes": [], "error": "No pathways for [G33275DG] could be generated at this time" }, { "glytoucan_ac": "G33303XH", "notes": [], "error": "No pathways for [G33303XH] could be generated at this time" }, { "glytoucan_ac": "G33309GL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G13210XL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G33309GL", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G33370EK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25097RR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 }, { "id": "G25097RR", "dp": 15 }, { "id": "G33370EK", "dp": 15 } ], "links": [ { "target": "G33370EK", "source": "G25097RR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33427JX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84778XH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G33427JX", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G33433QA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G54953LX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G33433QA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G33451YI", "notes": [], "error": "No pathways for [G33451YI] could be generated at this time" }, { "glytoucan_ac": "G33473DN", "notes": [], "error": "No pathways for [G33473DN] could be generated at this time" }, { "glytoucan_ac": "G33490PH", "notes": [], "error": "No pathways for [G33490PH] could be generated at this time" }, { "glytoucan_ac": "G33522ME", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G12061IK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G33522ME", "dp": 11 } ], "links": [ { "target": "G33522ME", "source": "G12061IK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33608TH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G33608TH] could be generated at this time" }, { "glytoucan_ac": "G33620BP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G27273FD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G33620BP", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G33685ZQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53752TA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G33685ZQ", "dp": 11 } ], "links": [ { "target": "G33685ZQ", "source": "G53752TA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33704YC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G38407OC", "dp": 12 } ], "links": [ { "target": "G33704YC", "source": "G38407OC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38407OC", "source": "G20815TK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33734YD", "notes": [], "error": "No pathways for [G33734YD] could be generated at this time" }, { "glytoucan_ac": "G33742YO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33748AU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G30085SO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G33748AU", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G33755SK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G33755SK] could be generated at this time" }, { "glytoucan_ac": "G33788DD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82894XV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G33788DD", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G33802UM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G33802UM] could be generated at this time" }, { "glytoucan_ac": "G33806LP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G33817TY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G66665YI", "dp": 14 } ], "links": [ { "target": "G33817TY", "source": "G66665YI", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66665YI", "source": "G66282NU", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33841EB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00413UF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G00413UF", "dp": 13 }, { "id": "G33841EB", "dp": 13 } ], "links": [ { "target": "G33841EB", "source": "G00413UF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00413UF", "source": "G84376FR", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33862NZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G33862NZ] could be generated at this time" }, { "glytoucan_ac": "G33894ZI", "notes": [], "error": "No pathways for [G33894ZI] could be generated at this time" }, { "glytoucan_ac": "G33909XJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 } ], "links": [ { "target": "G33909XJ", "source": "G81923ER", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33970VN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G79809MM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G33970VN", "dp": 11 } ], "links": [ { "target": "G33970VN", "source": "G79809MM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G33981FE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16546ZZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 }, { "id": "G16546ZZ", "dp": 13 }, { "id": "G33981FE", "dp": 13 } ], "links": [ { "target": "G33981FE", "source": "G16546ZZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16546ZZ", "source": "G41331JX", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34018EC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96963QG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G96963QG", "dp": 12 }, { "id": "G34018EC", "dp": 12 } ], "links": [ { "target": "G34018EC", "source": "G96963QG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34029JA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G34029JA", "source": "G25520XG", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34059IB", "notes": [], "error": "No pathways for [G34059IB] could be generated at this time" }, { "glytoucan_ac": "G34072RB", "notes": [], "error": "No pathways for [G34072RB] could be generated at this time" }, { "glytoucan_ac": "G34108KW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G34108KW] could be generated at this time" }, { "glytoucan_ac": "G34126VO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 } ], "links": [ { "target": "G34126VO", "source": "G60564DP", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34175ZP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 } ], "links": [ { "target": "G34175ZP", "source": "G01265XZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34220DL", "notes": [], "error": "No pathways for [G34220DL] could be generated at this time" }, { "glytoucan_ac": "G34276SS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G34276SS] could be generated at this time" }, { "glytoucan_ac": "G34314SG", "notes": [], "error": "No pathways for [G34314SG] could be generated at this time" }, { "glytoucan_ac": "G34330HT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G24413UY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 }, { "id": "G24413UY", "dp": 11 }, { "id": "G34330HT", "dp": 11 } ], "links": [ { "target": "G34330HT", "source": "G24413UY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G24413UY", "source": "G78890OB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34343FT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G79578JB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G34343FT", "dp": 12 } ], "links": [ { "target": "G34343FT", "source": "G79578JB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34383AG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99969SS]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 }, { "id": "G99969SS", "dp": 10 }, { "id": "G34383AG", "dp": 10 } ], "links": [ { "target": "G34383AG", "source": "G99969SS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99969SS", "source": "G13151XE", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34392KZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40341NV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G34392KZ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G34394BR", "notes": [], "error": "No pathways for [G34394BR] could be generated at this time" }, { "glytoucan_ac": "G34394KR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85891FA]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G34394KR", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G34442SS", "notes": [], "error": "No pathways for [G34442SS] could be generated at this time" }, { "glytoucan_ac": "G34483UH", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G34483UH] could be generated at this time" }, { "glytoucan_ac": "G34499SX", "notes": [], "error": "No pathways for [G34499SX] could be generated at this time" }, { "glytoucan_ac": "G34508UC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G34508UC] could be generated at this time" }, { "glytoucan_ac": "G34527RW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 } ], "links": [ { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34561BL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 }, { "id": "G57970NA", "dp": 13 } ], "links": [ { "target": "G34561BL", "source": "G57970NA", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G57970NA", "source": "G49515VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34585DT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66847YI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G34585DT", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G34595KJ", "notes": [], "error": "No pathways for [G34595KJ] could be generated at this time" }, { "glytoucan_ac": "G34603JX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G67943IR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G34603JX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G34612DX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80962OX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G80962OX", "dp": 9 }, { "id": "G34612DX", "dp": 9 } ], "links": [ { "target": "G34612DX", "source": "G80962OX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80962OX", "source": "G66937TJ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34626UE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G15998WM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 }, { "id": "G15998WM", "dp": 17 }, { "id": "G34626UE", "dp": 17 } ], "links": [ { "target": "G34626UE", "source": "G15998WM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G15998WM", "source": "G79950YS", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34634NL", "notes": [], "error": "No pathways for [G34634NL] could be generated at this time" }, { "glytoucan_ac": "G34650EM", "notes": [], "error": "No pathways for [G34650EM] could be generated at this time" }, { "glytoucan_ac": "G34669ZJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G34725PD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 } ], "links": [ { "target": "G34725PD", "source": "G30302VM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34731QC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G89865CB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G34731QC", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G34748WY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G91208VE", "dp": 9 } ], "links": [ { "target": "G34748WY", "source": "G91208VE", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34749PQ", "notes": [], "error": "No pathways for [G34749PQ] could be generated at this time" }, { "glytoucan_ac": "G34754UR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84879CH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G34754UR", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G34815RA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53933HU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G53933HU", "dp": 8 }, { "id": "G34815RA", "dp": 8 } ], "links": [ { "target": "G34815RA", "source": "G53933HU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53933HU", "source": "G59741XZ", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34819LS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G34819LS] could be generated at this time" }, { "glytoucan_ac": "G34821YB", "notes": [], "error": "No pathways for [G34821YB] could be generated at this time" }, { "glytoucan_ac": "G34822AT", "notes": [], "error": "No pathways for [G34822AT] could be generated at this time" }, { "glytoucan_ac": "G34838RM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 } ], "links": [ { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34852ZG", "notes": [], "error": "No pathways for [G34852ZG] could be generated at this time" }, { "glytoucan_ac": "G34859KW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G46470AD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 }, { "id": "G46470AD", "dp": 11 }, { "id": "G34859KW", "dp": 11 } ], "links": [ { "target": "G34859KW", "source": "G46470AD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46470AD", "source": "G01856RL", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34905OT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 } ], "links": [ { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34931KK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 } ], "links": [ { "target": "G34931KK", "source": "G62765SF", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34947FX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G92777SG", "dp": 11 } ], "links": [ { "target": "G34947FX", "source": "G92777SG", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G92777SG", "source": "G62504BU", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34972BB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 } ], "links": [ { "target": "G34972BB", "source": "G91905FJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G34985DS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G35053YZ", "notes": [], "error": "No pathways for [G35053YZ] could be generated at this time" }, { "glytoucan_ac": "G35096EN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G35096EN", "source": "G20030CU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35139NO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25097RR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 }, { "id": "G25097RR", "dp": 15 }, { "id": "G35139NO", "dp": 15 } ], "links": [ { "target": "G35139NO", "source": "G25097RR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35257SQ", "notes": [], "error": "No pathways for [G35257SQ] could be generated at this time" }, { "glytoucan_ac": "G35261RT", "notes": [], "error": "No pathways for [G35261RT] could be generated at this time" }, { "glytoucan_ac": "G35283JZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42240DE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G42240DE", "dp": 12 }, { "id": "G35283JZ", "dp": 12 } ], "links": [ { "target": "G35283JZ", "source": "G42240DE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G42240DE", "source": "G20815TK", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35310KA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 } ], "links": [ { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35347OW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 } ], "links": [ { "target": "G35347OW", "source": "G71679MX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35382VN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G35382VN] could be generated at this time" }, { "glytoucan_ac": "G35402TO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36787EI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G35402TO", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G35429JB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G67045LB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G35429JB", "dp": 8 } ], "links": [ { "target": "G35429JB", "source": "G67045LB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35438GZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24875YE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G35438GZ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G35442CG", "notes": [], "error": "No pathways for [G35442CG] could be generated at this time" }, { "glytoucan_ac": "G35455OM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 } ], "links": [ { "target": "G35455OM", "source": "G90870DG", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35459KZ", "notes": [], "error": "No pathways for [G35459KZ] could be generated at this time" }, { "glytoucan_ac": "G35482NV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G46503KK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G46503KK", "dp": 12 }, { "id": "G35482NV", "dp": 12 } ], "links": [ { "target": "G35482NV", "source": "G46503KK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46503KK", "source": "G18219CJ", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35484EX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07410AW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 }, { "id": "G07410AW", "dp": 14 }, { "id": "G35484EX", "dp": 14 } ], "links": [ { "target": "G35484EX", "source": "G07410AW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07410AW", "source": "G37597FW", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35565NM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 } ], "links": [ { "target": "G35565NM", "source": "G53485VW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35599NO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G35599NO] could be generated at this time" }, { "glytoucan_ac": "G35610QW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G35610QW] could be generated at this time" }, { "glytoucan_ac": "G35619UY", "notes": [], "error": "No pathways for [G35619UY] could be generated at this time" }, { "glytoucan_ac": "G35642GA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 }, { "id": "G37772CO", "dp": 11 } ], "links": [ { "target": "G35642GA", "source": "G37772CO", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G37772CO", "source": "G06969ZX", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35655SC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G74574VX", "dp": 11 }, { "id": "G83499UD", "dp": 12 } ], "links": [ { "target": "G35655SC", "source": "G83499UD", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G83499UD", "source": "G74574VX", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74574VX", "source": "G27123NH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35675LO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14068WV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 }, { "id": "G14068WV", "dp": 12 }, { "id": "G35675LO", "dp": 12 } ], "links": [ { "target": "G35675LO", "source": "G14068WV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14068WV", "source": "G04743RS", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35679TE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89168LM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G89168LM", "dp": 15 }, { "id": "G35679TE", "dp": 15 } ], "links": [ { "target": "G35679TE", "source": "G89168LM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89168LM", "source": "G63889NK", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35692YN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36004BS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G36004BS", "dp": 9 }, { "id": "G35692YN", "dp": 9 } ], "links": [ { "target": "G35692YN", "source": "G36004BS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36004BS", "source": "G12398HZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35708JV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G20885BK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G35708JV", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G35722YG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51793MY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G51793MY", "dp": 11 }, { "id": "G35722YG", "dp": 11 } ], "links": [ { "target": "G35722YG", "source": "G51793MY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G51793MY", "source": "G45560HM", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35732LD", "notes": [], "error": "No pathways for [G35732LD] could be generated at this time" }, { "glytoucan_ac": "G35734AU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97865QM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G35734AU", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G35747ZX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G35769UV", "notes": [], "error": "No pathways for [G35769UV] could be generated at this time" }, { "glytoucan_ac": "G35787ED", "notes": [], "error": "No pathways for [G35787ED] could be generated at this time" }, { "glytoucan_ac": "G35798GO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76554SR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G35798GO", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G35823EX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85895SP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G85895SP", "dp": 7 }, { "id": "G35823EX", "dp": 7 } ], "links": [ { "target": "G35823EX", "source": "G85895SP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85895SP", "source": "G61751GZ", "residue_affected": { "residue_id": "N306", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G35837ET", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G35878KK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G35878KK", "source": "G09782JM", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35888BV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G35888BV] could be generated at this time" }, { "glytoucan_ac": "G35888WG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G35888WG] could be generated at this time" }, { "glytoucan_ac": "G35912PE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G74574VX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G74574VX", "dp": 11 }, { "id": "G35912PE", "dp": 11 } ], "links": [ { "target": "G35912PE", "source": "G74574VX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74574VX", "source": "G27123NH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G35929YH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G41811VQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G35929YH", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G36004BS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G36004BS", "source": "G12398HZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36020VB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96925LL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36020VB", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G36042WR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G17964DY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36042WR", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G36053YX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G06131VP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G36053YX", "dp": 11 } ], "links": [ { "target": "G36053YX", "source": "G06131VP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36066DO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G65307KA", "dp": 12 } ], "links": [ { "target": "G36066DO", "source": "G65307KA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G65307KA", "source": "G10691MJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36108GD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 } ], "links": [ { "target": "G36108GD", "source": "G32305RZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36115SK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G36115SK] could be generated at this time" }, { "glytoucan_ac": "G36118RA", "notes": [], "error": "No pathways for [G36118RA] could be generated at this time" }, { "glytoucan_ac": "G36157OV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G36157OV", "source": "G91365ZQ", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36159AI", "notes": [], "error": "No pathways for [G36159AI] could be generated at this time" }, { "glytoucan_ac": "G36171JA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43346PX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 }, { "id": "G43346PX", "dp": 12 }, { "id": "G36171JA", "dp": 12 } ], "links": [ { "target": "G36171JA", "source": "G43346PX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43346PX", "source": "G04743RS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36176RV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 } ], "links": [ { "target": "G36176RV", "source": "G30302VM", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36191CD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36200ZL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G36200ZL] could be generated at this time" }, { "glytoucan_ac": "G36211GH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71957GO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36211GH", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G36218DJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G04791QM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G36218DJ", "dp": 9 } ], "links": [ { "target": "G36218DJ", "source": "G04791QM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36223VW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G36223VW] could be generated at this time" }, { "glytoucan_ac": "G36225RM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G36268TW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 } ], "links": [ { "target": "G36268TW", "source": "G77252PU", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36293DS", "notes": [], "error": "No pathways for [G36293DS] could be generated at this time" }, { "glytoucan_ac": "G36303CE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G18594ZT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36303CE", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G36306KM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G50023BR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36306KM", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G36316RB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G36316RB] could be generated at this time" }, { "glytoucan_ac": "G36324QX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G36324QX] could be generated at this time" }, { "glytoucan_ac": "G36362BK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G40428GO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36362BK", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G36378FM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G01669LU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G36378FM", "dp": 12 } ], "links": [ { "target": "G36378FM", "source": "G01669LU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36400RA", "notes": [], "error": "No pathways for [G36400RA] could be generated at this time" }, { "glytoucan_ac": "G36519NW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 } ], "links": [ { "target": "G36519NW", "source": "G01669LU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36521AS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G91208VE", "dp": 9 } ], "links": [ { "target": "G36521AS", "source": "G91208VE", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36523TZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G36523TZ", "source": "G29857RC", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36533LR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57565TQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36533LR", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G36542BE", "notes": [], "error": "No pathways for [G36542BE] could be generated at this time" }, { "glytoucan_ac": "G36581MF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G36581MF] could be generated at this time" }, { "glytoucan_ac": "G36581PT", "notes": [], "error": "No pathways for [G36581PT] could be generated at this time" }, { "glytoucan_ac": "G36588OE", "notes": [], "error": "No pathways for [G36588OE] could be generated at this time" }, { "glytoucan_ac": "G36608LK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27281KS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36608LK", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G36684NC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G28826SH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G36684NC", "dp": 10 } ], "links": [ { "target": "G36684NC", "source": "G28826SH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36699PG", "notes": [], "error": "No pathways for [G36699PG] could be generated at this time" }, { "glytoucan_ac": "G36701GV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 } ], "links": [ { "target": "G36701GV", "source": "G53752TA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36712XC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 } ], "links": [ { "target": "G36712XC", "source": "G09482NW", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36727AR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G66282NU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G36727AR", "dp": 13 } ], "links": [ { "target": "G36727AR", "source": "G66282NU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36749ZK", "notes": [], "error": "No pathways for [G36749ZK] could be generated at this time" }, { "glytoucan_ac": "G36759VO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G36766ZC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81528UX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G81528UX", "dp": 9 }, { "id": "G36766ZC", "dp": 9 } ], "links": [ { "target": "G36766ZC", "source": "G81528UX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G81528UX", "source": "G89993FE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36772MC", "notes": [], "error": "No pathways for [G36772MC] could be generated at this time" }, { "glytoucan_ac": "G36776KM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G13267ZY", "dp": 10 }, { "id": "G86681BW", "dp": 11 }, { "id": "G54775DO", "dp": 12 } ], "links": [ { "target": "G36776KM", "source": "G54775DO", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G54775DO", "source": "G86681BW", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G86681BW", "source": "G13267ZY", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G13267ZY", "source": "G46638GC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36787EI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G36787EI] could be generated at this time" }, { "glytoucan_ac": "G36816DT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G00951UF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G79198BK", "dp": 9 }, { "id": "G00951UF", "dp": 10 }, { "id": "G36816DT", "dp": 10 } ], "links": [ { "target": "G36816DT", "source": "G00951UF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00951UF", "source": "G79198BK", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G79198BK", "source": "G10219AA", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36859SD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66937TJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36859SD", "dp": 8 } ], "links": [ { "target": "G36859SD", "source": "G66937TJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36868UY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G36898CO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G77639OD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G36898CO", "dp": 10 } ], "links": [ { "target": "G36898CO", "source": "G77639OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36909MR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G75185NU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G36909MR", "dp": 12 } ], "links": [ { "target": "G36909MR", "source": "G75185NU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36909XX", "notes": [], "error": "No pathways for [G36909XX] could be generated at this time" }, { "glytoucan_ac": "G36960FP", "notes": [], "error": "No pathways for [G36960FP] could be generated at this time" }, { "glytoucan_ac": "G36977EW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G88417ED]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G36977EW", "dp": 10 } ], "links": [ { "target": "G36977EW", "source": "G88417ED", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G36978FH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75107JX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G36978FH", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G37022BP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 } ], "links": [ { "target": "G37022BP", "source": "G30460NZ", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37046CZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 } ], "links": [ { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37135JQ", "notes": [], "error": "No pathways for [G37135JQ] could be generated at this time" }, { "glytoucan_ac": "G37140SO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 } ], "links": [ { "target": "G37140SO", "source": "G93500PH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37166HP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 } ], "links": [ { "target": "G37166HP", "source": "G11637WL", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37210VL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G79457WN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G79457WN", "dp": 11 }, { "id": "G37210VL", "dp": 11 } ], "links": [ { "target": "G37210VL", "source": "G79457WN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79457WN", "source": "G00176HZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37260FV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78276SQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G78276SQ", "dp": 12 }, { "id": "G37260FV", "dp": 12 } ], "links": [ { "target": "G37260FV", "source": "G78276SQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78276SQ", "source": "G11041DA", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37274WB", "notes": [], "error": "No pathways for [G37274WB] could be generated at this time" }, { "glytoucan_ac": "G37276TY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74438AB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 }, { "id": "G74438AB", "dp": 12 }, { "id": "G37276TY", "dp": 12 } ], "links": [ { "target": "G37276TY", "source": "G74438AB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74438AB", "source": "G34905OT", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37291PT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G37304XT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40542QP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 }, { "id": "G40542QP", "dp": 15 }, { "id": "G37304XT", "dp": 15 } ], "links": [ { "target": "G37304XT", "source": "G40542QP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40542QP", "source": "G10228OD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37306TB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80537QW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G80537QW", "dp": 14 }, { "id": "G37306TB", "dp": 14 } ], "links": [ { "target": "G37306TB", "source": "G80537QW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80537QW", "source": "G93582HM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37385TT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 } ], "links": [ { "target": "G37385TT", "source": "G88417ED", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37476QB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 } ], "links": [ { "target": "G37476QB", "source": "G59741XZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37491LV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G91023GB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G37491LV", "dp": 12 } ], "links": [ { "target": "G37491LV", "source": "G91023GB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37492BZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G03260OU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G37492BZ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G37552GO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65239SF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 }, { "id": "G65239SF", "dp": 11 }, { "id": "G37552GO", "dp": 11 } ], "links": [ { "target": "G37552GO", "source": "G65239SF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65239SF", "source": "G81923ER", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37562WX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98115AV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G37562WX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G37581LU", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G19242QH]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G37581LU", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G37591JC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75850OP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G75850OP", "dp": 10 }, { "id": "G37591JC", "dp": 10 } ], "links": [ { "target": "G37591JC", "source": "G75850OP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75850OP", "source": "G36191CD", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37597FW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 } ], "links": [ { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37601IJ", "notes": [], "error": "No pathways for [G37601IJ] could be generated at this time" }, { "glytoucan_ac": "G37601UJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G91208VE", "dp": 9 } ], "links": [ { "target": "G37601UJ", "source": "G91208VE", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37612TM", "notes": [], "error": "No pathways for [G37612TM] could be generated at this time" }, { "glytoucan_ac": "G37626KE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G99866WK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G38395YJ", "dp": 14 }, { "id": "G99866WK", "dp": 15 }, { "id": "G37626KE", "dp": 15 } ], "links": [ { "target": "G37626KE", "source": "G99866WK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99866WK", "source": "G38395YJ", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G38395YJ", "source": "G00909PI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37718JO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 } ], "links": [ { "target": "G37718JO", "source": "G21755KD", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37745NY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G37772CO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 } ], "links": [ { "target": "G37772CO", "source": "G06969ZX", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37809PL", "notes": [], "error": "No pathways for [G37809PL] could be generated at this time" }, { "glytoucan_ac": "G37825LG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G44504SC", "dp": 10 } ], "links": [ { "target": "G37825LG", "source": "G44504SC", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G44504SC", "source": "G20030CU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37827FY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52080WL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G52080WL", "dp": 9 }, { "id": "G37827FY", "dp": 9 } ], "links": [ { "target": "G37827FY", "source": "G52080WL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52080WL", "source": "G66937TJ", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37841NF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G53168IY]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [G53168IY] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G37841WI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G55396DW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G55396DW", "dp": 12 }, { "id": "G37841WI", "dp": 12 } ], "links": [ { "target": "G37841WI", "source": "G55396DW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G55396DW", "source": "G25520XG", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37855JI", "notes": [], "error": "No pathways for [G37855JI] could be generated at this time" }, { "glytoucan_ac": "G37868JH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G87349YT", "dp": 13 } ], "links": [ { "target": "G37868JH", "source": "G87349YT", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G87349YT", "source": "G75049FP", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37919OJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90065BD]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G37919OJ", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G37938RD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G37938RD] could be generated at this time" }, { "glytoucan_ac": "G37986HU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84852GW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G84852GW", "dp": 9 }, { "id": "G37986HU", "dp": 9 } ], "links": [ { "target": "G37986HU", "source": "G84852GW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84852GW", "source": "G12398HZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G37990ZT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 } ], "links": [ { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38002QN", "notes": [], "error": "No pathways for [G38002QN] could be generated at this time" }, { "glytoucan_ac": "G38022PE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 } ], "links": [ { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38029ML", "notes": [], "error": "No pathways for [G38029ML] could be generated at this time" }, { "glytoucan_ac": "G38047QV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G34527RW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G38047QV", "dp": 8 } ], "links": [ { "target": "G38047QV", "source": "G34527RW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38085YD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G03445UI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 }, { "id": "G38085YD", "dp": 10 } ], "links": [ { "target": "G38085YD", "source": "G03445UI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38115KZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G71857KQ", "dp": 10 } ], "links": [ { "target": "G38115KZ", "source": "G71857KQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71857KQ", "source": "G29434RB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38121JC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G38121JC] could be generated at this time" }, { "glytoucan_ac": "G38159EA", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G19739KB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G38159EA", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G38208CY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G61684ET", "dp": 12 } ], "links": [ { "target": "G38208CY", "source": "G61684ET", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G61684ET", "source": "G25520XG", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38236XZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G38236XZ", "source": "G00176HZ", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38241TC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G38249IZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G17540HT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 }, { "id": "G17540HT", "dp": 12 }, { "id": "G38249IZ", "dp": 12 } ], "links": [ { "target": "G38249IZ", "source": "G17540HT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17540HT", "source": "G30460NZ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38267IW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80717KS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G38267IW", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G38271CW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G28550OD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G28550OD", "dp": 9 }, { "id": "G38271CW", "dp": 9 } ], "links": [ { "target": "G38271CW", "source": "G28550OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28550OD", "source": "G12398HZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38291RB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 } ], "links": [ { "target": "G38291RB", "source": "G45359RY", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38297TU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08520NM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G38297TU", "dp": 8 } ], "links": [ { "target": "G38297TU", "source": "G08520NM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G38362AS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G14996IQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G14996IQ", "dp": 8 }, { "id": "G38362AS", "dp": 8 } ], "links": [ { "target": "G38362AS", "source": "G14996IQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14996IQ", "source": "G69411IG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38371WW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50943ZX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G50943ZX", "dp": 9 }, { "id": "G38371WW", "dp": 9 } ], "links": [ { "target": "G38371WW", "source": "G50943ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50943ZX", "source": "G20956ZK", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38373BD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G44904UE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G38373BD", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G38395YJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 } ], "links": [ { "target": "G38395YJ", "source": "G00909PI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38404PP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G25326BM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G25326BM", "dp": 9 }, { "id": "G38404PP", "dp": 9 } ], "links": [ { "target": "G38404PP", "source": "G25326BM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25326BM", "source": "G89993FE", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38407OC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 } ], "links": [ { "target": "G38407OC", "source": "G20815TK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38488ZJ", "notes": [], "error": "No pathways for [G38488ZJ] could be generated at this time" }, { "glytoucan_ac": "G38549YL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G21679ID", "dp": 11 } ], "links": [ { "target": "G38549YL", "source": "G21679ID", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G21679ID", "source": "G52934AK", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38625SV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G67549HD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G38625SV", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G38637SA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G38637SA] could be generated at this time" }, { "glytoucan_ac": "G38638WU", "notes": [], "error": "No pathways for [G38638WU] could be generated at this time" }, { "glytoucan_ac": "G38658JL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04273XP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G03385XG", "dp": 13 }, { "id": "G04273XP", "dp": 14 }, { "id": "G38658JL", "dp": 14 } ], "links": [ { "target": "G38658JL", "source": "G04273XP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04273XP", "source": "G03385XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G03385XG", "source": "G01669LU", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38659HF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90670ZD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G97093EP", "dp": 12 }, { "id": "G90670ZD", "dp": 13 }, { "id": "G38659HF", "dp": 13 } ], "links": [ { "target": "G38659HF", "source": "G90670ZD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90670ZD", "source": "G97093EP", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G97093EP", "source": "G43433FA", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38663XJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G99645NK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G38663XJ", "dp": 11 } ], "links": [ { "target": "G38663XJ", "source": "G99645NK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38668OJ", "notes": [], "error": "No pathways for [G38668OJ] could be generated at this time" }, { "glytoucan_ac": "G38753OV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G38753OV", "source": "G52934AK", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38800CP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G38849GM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G38867AF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G38901GU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98453VS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G38901GU", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G38951VC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 }, { "id": "G53000RQ", "dp": 11 } ], "links": [ { "target": "G38951VC", "source": "G53000RQ", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53000RQ", "source": "G12740VA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38955TH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G40806JH", "dp": 11 } ], "links": [ { "target": "G38955TH", "source": "G40806JH", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G38966ID", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39089YD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G38966ID", "dp": 7 } ], "links": [ { "target": "G38966ID", "source": "G39089YD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G38997JB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98115AV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G38997JB", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G39018CC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G25505UF", "dp": 14 } ], "links": [ { "target": "G39018CC", "source": "G25505UF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39027MU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G39027MU] could be generated at this time" }, { "glytoucan_ac": "G39029JR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 } ], "links": [ { "target": "G39029JR", "source": "G93500PH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39035OI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G29857PJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G39035OI", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G39062YR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72821WX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G72821WX", "dp": 9 }, { "id": "G39062YR", "dp": 9 } ], "links": [ { "target": "G39062YR", "source": "G72821WX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72821WX", "source": "G12398HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39089YD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G39111QK", "notes": [], "error": "No pathways for [G39111QK] could be generated at this time" }, { "glytoucan_ac": "G39119ZF", "notes": [], "error": "No pathways for [G39119ZF] could be generated at this time" }, { "glytoucan_ac": "G39125OY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G39174FS", "notes": [], "error": "No pathways for [G39174FS] could be generated at this time" }, { "glytoucan_ac": "G39181YB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G39183DW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28957FB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G39183DW", "dp": 15 } ], "links": [ { "target": "G39183DW", "source": "G28957FB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39213VZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39298CN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40096SL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G39298CN", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G39298RF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G71690HK", "dp": 10 } ], "links": [ { "target": "G39298RF", "source": "G71690HK", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G71690HK", "source": "G61207RZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39299DH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G39318IJ", "notes": [], "error": "No pathways for [G39318IJ] could be generated at this time" }, { "glytoucan_ac": "G39338NX", "notes": [], "error": "No pathways for [G39338NX] could be generated at this time" }, { "glytoucan_ac": "G39340CD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00666EC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G39340CD", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G39344CL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G39344CL] could be generated at this time" }, { "glytoucan_ac": "G39353RT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 } ], "links": [ { "target": "G39353RT", "source": "G35310KA", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39377DE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 } ], "links": [ { "target": "G39377DE", "source": "G09921WG", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39377JQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G68313WI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G39377JQ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G39383KR", "notes": [], "error": "No pathways for [G39383KR] could be generated at this time" }, { "glytoucan_ac": "G39394NX", "notes": [], "error": "No pathways for [G39394NX] could be generated at this time" }, { "glytoucan_ac": "G39407WQ", "notes": [], "error": "No pathways for [G39407WQ] could be generated at this time" }, { "glytoucan_ac": "G39408YK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G39408YK", "source": "G25520XG", "residue_affected": { "residue_id": "N368", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39437XQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99897FQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G99897FQ", "dp": 9 }, { "id": "G39437XQ", "dp": 9 } ], "links": [ { "target": "G39437XQ", "source": "G99897FQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99897FQ", "source": "G67045LB", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39439UR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 } ], "links": [ { "target": "G39439UR", "source": "G10209QU", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39452ZZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45359RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G39452ZZ", "dp": 12 } ], "links": [ { "target": "G39452ZZ", "source": "G45359RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39465KG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G91550OH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G39465KG", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G39473HX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G65981EG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G37385TT", "dp": 11 }, { "id": "G65981EG", "dp": 12 }, { "id": "G39473HX", "dp": 12 } ], "links": [ { "target": "G39473HX", "source": "G65981EG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65981EG", "source": "G37385TT", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G37385TT", "source": "G88417ED", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39478RR", "notes": [], "error": "No pathways for [G39478RR] could be generated at this time" }, { "glytoucan_ac": "G39504IG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 } ], "links": [ { "target": "G39504IG", "source": "G79809MM", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39509DP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G46021KV", "dp": 12 }, { "id": "G12203WB", "dp": 13 } ], "links": [ { "target": "G39509DP", "source": "G12203WB", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G12203WB", "source": "G46021KV", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G46021KV", "source": "G29857RC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39531LA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66665YI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G66665YI", "dp": 14 }, { "id": "G39531LA", "dp": 14 } ], "links": [ { "target": "G39531LA", "source": "G66665YI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66665YI", "source": "G66282NU", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39540XG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G25835MT", "dp": 10 }, { "id": "G10258MC", "dp": 11 } ], "links": [ { "target": "G39540XG", "source": "G10258MC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10258MC", "source": "G25835MT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39567LQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G45209NR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G45209NR", "dp": 15 }, { "id": "G39567LQ", "dp": 15 } ], "links": [ { "target": "G39567LQ", "source": "G45209NR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45209NR", "source": "G91905FJ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39578OU", "notes": [], "error": "No pathways for [G39578OU] could be generated at this time" }, { "glytoucan_ac": "G39585RN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 } ], "links": [ { "target": "G39585RN", "source": "G08194HH", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39595CR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 } ], "links": [ { "target": "G39595CR", "source": "G80294GH", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39600NF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94679TQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G39600NF", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G39601JQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G39601JQ] could be generated at this time" }, { "glytoucan_ac": "G39602UU", "notes": [], "error": "No pathways for [G39602UU] could be generated at this time" }, { "glytoucan_ac": "G39623FZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G34527RW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G39623FZ", "dp": 8 } ], "links": [ { "target": "G39623FZ", "source": "G34527RW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39662GV", "notes": [], "error": "No pathways for [G39662GV] could be generated at this time" }, { "glytoucan_ac": "G39687WG", "notes": [], "error": "No pathways for [G39687WG] could be generated at this time" }, { "glytoucan_ac": "G39691JY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17413FR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 }, { "id": "G17413FR", "dp": 13 }, { "id": "G39691JY", "dp": 13 } ], "links": [ { "target": "G39691JY", "source": "G17413FR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17413FR", "source": "G56749GV", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39722LF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G39756ZC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34725PD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G34725PD", "dp": 12 }, { "id": "G39756ZC", "dp": 12 } ], "links": [ { "target": "G39756ZC", "source": "G34725PD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34725PD", "source": "G30302VM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39764AC", "notes": [], "error": "No pathways for [G39764AC] could be generated at this time" }, { "glytoucan_ac": "G39765RY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G62880PC", "dp": 9 }, { "id": "G45686NF", "dp": 10 } ], "links": [ { "target": "G39765RY", "source": "G45686NF", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G45686NF", "source": "G62880PC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62880PC", "source": "G59471TH", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39794DN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77639OD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G39794DN", "dp": 10 } ], "links": [ { "target": "G39794DN", "source": "G77639OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39809FW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88382QE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G88382QE", "dp": 14 }, { "id": "G39809FW", "dp": 14 } ], "links": [ { "target": "G39809FW", "source": "G88382QE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88382QE", "source": "G18938DW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39813YP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 } ], "links": [ { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G39829HV", "notes": [], "error": "No pathways for [G39829HV] could be generated at this time" }, { "glytoucan_ac": "G39893KL", "notes": [], "error": "No pathways for [G39893KL] could be generated at this time" }, { "glytoucan_ac": "G39906AT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G39976KS", "notes": [], "error": "No pathways for [G39976KS] could be generated at this time" }, { "glytoucan_ac": "G39977UQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G39977UQ] could be generated at this time" }, { "glytoucan_ac": "G39992DR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G70708LW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 }, { "id": "G70708LW", "dp": 12 }, { "id": "G39992DR", "dp": 12 } ], "links": [ { "target": "G39992DR", "source": "G70708LW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70708LW", "source": "G74675FC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40027VO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G40027VO] could be generated at this time" }, { "glytoucan_ac": "G40033UH", "notes": [], "error": "No pathways for [G40033UH] could be generated at this time" }, { "glytoucan_ac": "G40064GR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G40064GR] could be generated at this time" }, { "glytoucan_ac": "G40065EM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G28298VW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 }, { "id": "G28298VW", "dp": 13 }, { "id": "G40065EM", "dp": 13 } ], "links": [ { "target": "G40065EM", "source": "G28298VW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28298VW", "source": "G48658PB", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40069AV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G40079RD", "notes": [], "error": "No pathways for [G40079RD] could be generated at this time" }, { "glytoucan_ac": "G40095NL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24635ZS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G40095NL", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G40096SL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G40096SL] could be generated at this time" }, { "glytoucan_ac": "G40097PQ", "notes": [], "error": "No pathways for [G40097PQ] could be generated at this time" }, { "glytoucan_ac": "G40142NX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G80962OX", "dp": 9 } ], "links": [ { "target": "G40142NX", "source": "G80962OX", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80962OX", "source": "G66937TJ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40173TB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19615BB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 }, { "id": "G08242BT", "dp": 12 }, { "id": "G19615BB", "dp": 13 }, { "id": "G40173TB", "dp": 13 } ], "links": [ { "target": "G40173TB", "source": "G19615BB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19615BB", "source": "G08242BT", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G08242BT", "source": "G26949IX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40181EN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G40194MN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 } ], "links": [ { "target": "G40194MN", "source": "G76842ZR", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40198OD", "notes": [], "error": "No pathways for [G40198OD] could be generated at this time" }, { "glytoucan_ac": "G40200RC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10295MW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G40200RC", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G40244KN", "notes": [], "error": "No pathways for [G40244KN] could be generated at this time" }, { "glytoucan_ac": "G40264QS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21311YA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G21311YA", "dp": 12 }, { "id": "G40264QS", "dp": 12 } ], "links": [ { "target": "G40264QS", "source": "G21311YA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21311YA", "source": "G11041DA", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40268BC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03272YQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G21788RU", "dp": 12 }, { "id": "G03272YQ", "dp": 13 }, { "id": "G40268BC", "dp": 13 } ], "links": [ { "target": "G40268BC", "source": "G03272YQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03272YQ", "source": "G21788RU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G21788RU", "source": "G25520XG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40289RO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 } ], "links": [ { "target": "G40289RO", "source": "G20966TZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40317YZ", "notes": [], "error": "No pathways for [G40317YZ] could be generated at this time" }, { "glytoucan_ac": "G40341NV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G40341NV] could be generated at this time" }, { "glytoucan_ac": "G40343KH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57835AK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G40343KH", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G40352EF", "notes": [], "error": "No pathways for [G40352EF] could be generated at this time" }, { "glytoucan_ac": "G40358EZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G40358EZ", "source": "G00176HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40428GO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G40428GO] could be generated at this time" }, { "glytoucan_ac": "G40447LJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G98809PE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G40447LJ", "dp": 12 } ], "links": [ { "target": "G40447LJ", "source": "G98809PE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40452FK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G40461OS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G26018HD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G26018HD", "dp": 12 }, { "id": "G40461OS", "dp": 12 } ], "links": [ { "target": "G40461OS", "source": "G26018HD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26018HD", "source": "G90870DG", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40482NA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28948UC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G28948UC", "dp": 12 }, { "id": "G40482NA", "dp": 12 } ], "links": [ { "target": "G40482NA", "source": "G28948UC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28948UC", "source": "G10691MJ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40493BL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G81085EP", "dp": 11 } ], "links": [ { "target": "G40493BL", "source": "G81085EP", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G81085EP", "source": "G87073UP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40513EI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G13282WA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G40513EI", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G40542QP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 } ], "links": [ { "target": "G40542QP", "source": "G10228OD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40554DX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 } ], "links": [ { "target": "G40554DX", "source": "G75120WS", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40558VT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38951VC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 }, { "id": "G53000RQ", "dp": 11 }, { "id": "G38951VC", "dp": 12 }, { "id": "G40558VT", "dp": 12 } ], "links": [ { "target": "G40558VT", "source": "G38951VC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38951VC", "source": "G53000RQ", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53000RQ", "source": "G12740VA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40569DS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58827HR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G40569DS", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G40579SX", "notes": [], "error": "No pathways for [G40579SX] could be generated at this time" }, { "glytoucan_ac": "G40606GB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 } ], "links": [ { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40670DJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G40670DJ] could be generated at this time" }, { "glytoucan_ac": "G40702WU", "notes": [], "error": "No pathways for [G40702WU] could be generated at this time" }, { "glytoucan_ac": "G40707SF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G40707SF] could be generated at this time" }, { "glytoucan_ac": "G40735XY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79198BK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G79198BK", "dp": 9 }, { "id": "G40735XY", "dp": 9 } ], "links": [ { "target": "G40735XY", "source": "G79198BK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79198BK", "source": "G10219AA", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40762ZY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 } ], "links": [ { "target": "G40762ZY", "source": "G28826SH", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40786FB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06216UH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G06216UH", "dp": 10 }, { "id": "G40786FB", "dp": 10 } ], "links": [ { "target": "G40786FB", "source": "G06216UH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40806JH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 } ], "links": [ { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40813TL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 } ], "links": [ { "target": "G40813TL", "source": "G20815TK", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40821RK", "notes": [], "error": "No pathways for [G40821RK] could be generated at this time" }, { "glytoucan_ac": "G40900UQ", "notes": [], "error": "No pathways for [G40900UQ] could be generated at this time" }, { "glytoucan_ac": "G40903ZD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G34819LS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G40903ZD", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G40906DZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G40906DZ", "source": "G18938DW", "residue_affected": { "residue_id": "N43", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40909AN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G40909AN] could be generated at this time" }, { "glytoucan_ac": "G40915GX", "notes": [], "error": "No pathways for [G40915GX] could be generated at this time" }, { "glytoucan_ac": "G40922OB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82420SH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G82420SH", "dp": 10 }, { "id": "G40922OB", "dp": 10 } ], "links": [ { "target": "G40922OB", "source": "G82420SH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82420SH", "source": "G45262QY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G40994FC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G45359RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G40994FC", "dp": 12 } ], "links": [ { "target": "G40994FC", "source": "G45359RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41015OA", "notes": [], "error": "No pathways for [G41015OA] could be generated at this time" }, { "glytoucan_ac": "G41087ZA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G41087ZA] could be generated at this time" }, { "glytoucan_ac": "G41095QB", "notes": [], "error": "No pathways for [G41095QB] could be generated at this time" }, { "glytoucan_ac": "G41107EH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08896RO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G41107EH", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G41125AS", "notes": [], "error": "No pathways for [G41125AS] could be generated at this time" }, { "glytoucan_ac": "G41178NB", "notes": [], "error": "No pathways for [G41178NB] could be generated at this time" }, { "glytoucan_ac": "G41263IO", "notes": [], "error": "No pathways for [G41263IO] could be generated at this time" }, { "glytoucan_ac": "G41278YY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G82540VC", "dp": 8 } ], "links": [ { "target": "G41278YY", "source": "G82540VC", "residue_affected": { "residue_id": "N238", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G82540VC", "source": "G39213VZ", "residue_affected": { "residue_id": "N250", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41310VR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42028DN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G42028DN", "dp": 11 }, { "id": "G41310VR", "dp": 11 } ], "links": [ { "target": "G41310VR", "source": "G42028DN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G42028DN", "source": "G09921WG", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41331JX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41352UL", "notes": [], "error": "No pathways for [G41352UL] could be generated at this time" }, { "glytoucan_ac": "G41389FB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 } ], "links": [ { "target": "G41389FB", "source": "G65597BI", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41389HP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G24155DW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G41389HP", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G41455NO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G12222NC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G41455NO", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G41486SZ", "notes": [], "error": "No pathways for [G41486SZ] could be generated at this time" }, { "glytoucan_ac": "G41504VL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G41504VL] could be generated at this time" }, { "glytoucan_ac": "G41510DX", "notes": [], "error": "No pathways for [G41510DX] could be generated at this time" }, { "glytoucan_ac": "G41551CD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G97039HI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G41551CD", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G41563EN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G41576FY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G79809MM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G41576FY", "dp": 11 } ], "links": [ { "target": "G41576FY", "source": "G79809MM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41596PV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G41596PV] could be generated at this time" }, { "glytoucan_ac": "G41611UP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 } ], "links": [ { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41656NL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 } ], "links": [ { "target": "G41656NL", "source": "G23616ZX", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41670EF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G41711ZZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G41711ZZ] could be generated at this time" }, { "glytoucan_ac": "G41720HN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G41720HN", "source": "G07483YN", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41797PU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G41797PU] could be generated at this time" }, { "glytoucan_ac": "G41800OU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27273FD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G41800OU", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G41811PH", "notes": [], "error": "No pathways for [G41811PH] could be generated at this time" }, { "glytoucan_ac": "G41811VQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G41811VQ] could be generated at this time" }, { "glytoucan_ac": "G41817BL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17264LS]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G17264LS", "dp": 10 }, { "id": "G41817BL", "dp": 10 } ], "links": [ { "target": "G41817BL", "source": "G17264LS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17264LS", "source": "G16828VN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41820ZZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 } ], "links": [ { "target": "G41820ZZ", "source": "G45560HM", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41821MR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52880ZN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G52880ZN", "dp": 12 }, { "id": "G41821MR", "dp": 12 } ], "links": [ { "target": "G41821MR", "source": "G52880ZN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52880ZN", "source": "G82252QI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41824PC", "notes": [], "error": "No pathways for [G41824PC] could be generated at this time" }, { "glytoucan_ac": "G41827IE", "notes": [], "error": "No pathways for [G41827IE] could be generated at this time" }, { "glytoucan_ac": "G41847IM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89036WC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G89036WC", "dp": 8 }, { "id": "G41847IM", "dp": 8 } ], "links": [ { "target": "G41847IM", "source": "G89036WC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89036WC", "source": "G69411IG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41850YN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G91413ZX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G91413ZX", "dp": 15 }, { "id": "G41850YN", "dp": 15 } ], "links": [ { "target": "G41850YN", "source": "G91413ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41865ZJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G50779LX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 }, { "id": "G50779LX", "dp": 12 }, { "id": "G41865ZJ", "dp": 12 } ], "links": [ { "target": "G41865ZJ", "source": "G50779LX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50779LX", "source": "G25140TA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41879EJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G41912CL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75097MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G41912CL", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G41923EO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G62504BU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G41923EO", "dp": 10 } ], "links": [ { "target": "G41923EO", "source": "G62504BU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41937ED", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G05794RZ]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G40806JH", "dp": 11 }, { "id": "G05794RZ", "dp": 12 }, { "id": "G41937ED", "dp": 12 } ], "links": [ { "target": "G41937ED", "source": "G05794RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G05794RZ", "source": "G40806JH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G41940YX", "notes": [], "error": "No pathways for [G41940YX] could be generated at this time" }, { "glytoucan_ac": "G41943OZ", "notes": [], "error": "No pathways for [G41943OZ] could be generated at this time" }, { "glytoucan_ac": "G41953RN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G41953RN] could be generated at this time" }, { "glytoucan_ac": "G41974MG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G02025MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G41974MG", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G41981MA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 } ], "links": [ { "target": "G41981MA", "source": "G38022PE", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42013HP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G20815TK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G42013HP", "dp": 11 } ], "links": [ { "target": "G42013HP", "source": "G20815TK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42022OY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G42022OY] could be generated at this time" }, { "glytoucan_ac": "G42028DN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 } ], "links": [ { "target": "G42028DN", "source": "G09921WG", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42028VS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G01935FK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01935FK", "dp": 10 }, { "id": "G42028VS", "dp": 10 } ], "links": [ { "target": "G42028VS", "source": "G01935FK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01935FK", "source": "G36191CD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42058RF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G42061BV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G73492AT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G42061BV", "dp": 13 } ], "links": [ { "target": "G42061BV", "source": "G73492AT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42095CU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98537XO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G42095CU", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G42097JO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 } ], "links": [ { "target": "G42097JO", "source": "G85085MS", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42110JE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G21359NQ", "dp": 11 } ], "links": [ { "target": "G42110JE", "source": "G21359NQ", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G21359NQ", "source": "G32305RZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42130KX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G42130KX] could be generated at this time" }, { "glytoucan_ac": "G42175IR", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G42175IR] could be generated at this time" }, { "glytoucan_ac": "G42177JE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97039HI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G42177JE", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G42193NQ", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G56748EO", "dp": 10 } ], "links": [ { "target": "G42193NQ", "source": "G56748EO", "residue_affected": { "residue_id": "N373", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42240DE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 } ], "links": [ { "target": "G42240DE", "source": "G20815TK", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42295MA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91023GB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G42295MA", "dp": 12 } ], "links": [ { "target": "G42295MA", "source": "G91023GB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42322YV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 } ], "links": [ { "target": "G42322YV", "source": "G14782PJ", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42343WF", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G10989IB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 }, { "id": "G95404EQ", "dp": 17 }, { "id": "G31004HS", "dp": 18 }, { "id": "G10989IB", "dp": 19 }, { "id": "G42343WF", "dp": 19 } ], "links": [ { "target": "G42343WF", "source": "G10989IB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10989IB", "source": "G31004HS", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G31004HS", "source": "G95404EQ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42365AT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 } ], "links": [ { "target": "G42365AT", "source": "G77252PU", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42372YG", "notes": [], "error": "No pathways for [G42372YG] could be generated at this time" }, { "glytoucan_ac": "G42380GI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G56318NV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G75237SS", "dp": 16 }, { "id": "G56318NV", "dp": 17 }, { "id": "G42380GI", "dp": 17 } ], "links": [ { "target": "G42380GI", "source": "G56318NV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56318NV", "source": "G75237SS", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42400JK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G69086TY", "dp": 12 } ], "links": [ { "target": "G42400JK", "source": "G69086TY", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42415XD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91511MZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G91511MZ", "dp": 12 }, { "id": "G42415XD", "dp": 12 } ], "links": [ { "target": "G42415XD", "source": "G91511MZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91511MZ", "source": "G11041DA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42438ZG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G42438ZG] could be generated at this time" }, { "glytoucan_ac": "G42439GB", "notes": [], "error": "No pathways for [G42439GB] could be generated at this time" }, { "glytoucan_ac": "G42477ZH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G42477ZH] could be generated at this time" }, { "glytoucan_ac": "G42501VF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G57863LA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G57863LA", "dp": 11 }, { "id": "G42501VF", "dp": 11 } ], "links": [ { "target": "G42501VF", "source": "G57863LA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57863LA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42504VW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G42525DE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49743VF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G06216UH", "dp": 10 }, { "id": "G49743VF", "dp": 11 }, { "id": "G42525DE", "dp": 11 } ], "links": [ { "target": "G42525DE", "source": "G49743VF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49743VF", "source": "G06216UH", "residue_affected": { "residue_id": "N470", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42548XF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G42548XF", "source": "G61751GZ", "residue_affected": { "residue_id": "N204", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] } ] } , { "glytoucan_ac": "G42552PM", "notes": [], "error": "No pathways for [G42552PM] could be generated at this time" }, { "glytoucan_ac": "G42600SB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G98366ZJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 }, { "id": "G98366ZJ", "dp": 14 }, { "id": "G42600SB", "dp": 14 } ], "links": [ { "target": "G42600SB", "source": "G98366ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98366ZJ", "source": "G99074EO", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42605KJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78097CL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G09150LP", "dp": 12 }, { "id": "G78097CL", "dp": 13 }, { "id": "G42605KJ", "dp": 13 } ], "links": [ { "target": "G42605KJ", "source": "G78097CL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78097CL", "source": "G09150LP", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G09150LP", "source": "G88948CY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42619IV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 } ], "links": [ { "target": "G42619IV", "source": "G75185NU", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42653GO", "notes": [], "error": "No pathways for [G42653GO] could be generated at this time" }, { "glytoucan_ac": "G42672MA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42674AX", "notes": [], "error": "No pathways for [G42674AX] could be generated at this time" }, { "glytoucan_ac": "G42674LI", "notes": [], "error": "No pathways for [G42674LI] could be generated at this time" }, { "glytoucan_ac": "G42679AH", "notes": [], "error": "No pathways for [G42679AH] could be generated at this time" }, { "glytoucan_ac": "G42680EX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G61751GZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G42680EX", "dp": 6 } ], "links": [ { "target": "G42680EX", "source": "G61751GZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G42686NP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G42686NQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 } ], "links": [ { "target": "G42686NQ", "source": "G19726AG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42712XS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G64633BH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G64633BH", "dp": 9 }, { "id": "G42712XS", "dp": 9 } ], "links": [ { "target": "G42712XS", "source": "G64633BH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G64633BH", "source": "G79348ZY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42713FO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G56340GX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G56340GX", "dp": 10 }, { "id": "G42713FO", "dp": 10 } ], "links": [ { "target": "G42713FO", "source": "G56340GX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56340GX", "source": "G27919IH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42731RJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G42731RJ] could be generated at this time" }, { "glytoucan_ac": "G42824AQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G92574YO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G42824AQ", "dp": 17 } ], "links": [ { "target": "G42824AQ", "source": "G92574YO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42830YF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G18938DW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G42830YF", "dp": 13 } ], "links": [ { "target": "G42830YF", "source": "G18938DW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42841BX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G42846BO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G91365ZQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G42846BO", "dp": 10 } ], "links": [ { "target": "G42846BO", "source": "G91365ZQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42862VU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G95298UR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G42862VU", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G42909GK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G42909GK] could be generated at this time" }, { "glytoucan_ac": "G42941KJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84712FF", "dp": 12 } ], "links": [ { "target": "G42941KJ", "source": "G84712FF", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84712FF", "source": "G29857RC", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G42984ZU", "notes": [], "error": "No pathways for [G42984ZU] could be generated at this time" }, { "glytoucan_ac": "G43014FZ", "notes": [], "error": "No pathways for [G43014FZ] could be generated at this time" }, { "glytoucan_ac": "G43040IL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43040IL] could be generated at this time" }, { "glytoucan_ac": "G43048HN", "notes": [], "error": "No pathways for [G43048HN] could be generated at this time" }, { "glytoucan_ac": "G43070PV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53485VW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 }, { "id": "G43070PV", "dp": 14 } ], "links": [ { "target": "G43070PV", "source": "G53485VW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43072YM", "notes": [], "error": "No pathways for [G43072YM] could be generated at this time" }, { "glytoucan_ac": "G43088GK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43088GK] could be generated at this time" }, { "glytoucan_ac": "G43131ZX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G89168LM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G89168LM", "dp": 15 }, { "id": "G43131ZX", "dp": 15 } ], "links": [ { "target": "G43131ZX", "source": "G89168LM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89168LM", "source": "G63889NK", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43164CL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84712FF", "dp": 12 } ], "links": [ { "target": "G43164CL", "source": "G84712FF", "residue_affected": { "residue_id": "N130", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [] }, { "target": "G84712FF", "source": "G29857RC", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43242DB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G88537BJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 }, { "id": "G88537BJ", "dp": 15 }, { "id": "G43242DB", "dp": 15 } ], "links": [ { "target": "G43242DB", "source": "G88537BJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88537BJ", "source": "G23616ZX", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43255OW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G48954CA", "dp": 9 } ], "links": [ { "target": "G43255OW", "source": "G48954CA", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G48954CA", "source": "G12398HZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43288IJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43288IJ] could be generated at this time" }, { "glytoucan_ac": "G43299SD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43301PF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G84376FR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G43301PF", "dp": 12 } ], "links": [ { "target": "G43301PF", "source": "G84376FR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43325ZI", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G43325ZI] could be generated at this time" }, { "glytoucan_ac": "G43346PX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 } ], "links": [ { "target": "G43346PX", "source": "G04743RS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43351VW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43351VW] could be generated at this time" }, { "glytoucan_ac": "G43433FA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 } ], "links": [ { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43447HY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G43473VD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G09921WG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G43473VD", "dp": 10 } ], "links": [ { "target": "G43473VD", "source": "G09921WG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43475FH", "notes": [], "error": "No pathways for [G43475FH] could be generated at this time" }, { "glytoucan_ac": "G43499QE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19444JC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G19444JC", "dp": 15 }, { "id": "G43499QE", "dp": 15 } ], "links": [ { "target": "G43499QE", "source": "G19444JC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19444JC", "source": "G45720CA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43507KQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G09826WW", "dp": 11 } ], "links": [ { "target": "G43507KQ", "source": "G09826WW", "residue_affected": { "residue_id": "N272", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G09826WW", "source": "G85542KD", "residue_affected": { "residue_id": "N271", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43526DL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G96674LJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G96674LJ", "dp": 18 }, { "id": "G43526DL", "dp": 18 } ], "links": [ { "target": "G43526DL", "source": "G96674LJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96674LJ", "source": "G50489VC", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43526DV", "notes": [], "error": "No pathways for [G43526DV] could be generated at this time" }, { "glytoucan_ac": "G43547MI", "notes": [], "error": "No pathways for [G43547MI] could be generated at this time" }, { "glytoucan_ac": "G43553YK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G57092OJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G57092OJ", "dp": 10 }, { "id": "G43553YK", "dp": 10 } ], "links": [ { "target": "G43553YK", "source": "G57092OJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57092OJ", "source": "G58667NI", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43558RC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42909GK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G43558RC", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G43603TQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30651IU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 }, { "id": "G43603TQ", "dp": 13 } ], "links": [ { "target": "G43603TQ", "source": "G30651IU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43610AB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G37140SO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G37140SO", "dp": 10 }, { "id": "G43610AB", "dp": 10 } ], "links": [ { "target": "G43610AB", "source": "G37140SO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37140SO", "source": "G93500PH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43648DB", "notes": [], "error": "No pathways for [G43648DB] could be generated at this time" }, { "glytoucan_ac": "G43654PQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G80652ZF", "dp": 8 } ], "links": [ { "target": "G43654PQ", "source": "G80652ZF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80652ZF", "source": "G39213VZ", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43657WC", "notes": [], "error": "No pathways for [G43657WC] could be generated at this time" }, { "glytoucan_ac": "G43660IT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95919TI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 }, { "id": "G95919TI", "dp": 14 }, { "id": "G43660IT", "dp": 14 } ], "links": [ { "target": "G43660IT", "source": "G95919TI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95919TI", "source": "G30651IU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43664YB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 } ], "links": [ { "target": "G43664YB", "source": "G24420RT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43665PB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G79556AB", "dp": 12 } ], "links": [ { "target": "G43665PB", "source": "G79556AB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79556AB", "source": "G82252QI", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43677TG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43685DC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85208SY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G43685DC", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G43694RQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43702IX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 } ], "links": [ { "target": "G43702IX", "source": "G23616ZX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43708QI", "notes": [], "error": "No pathways for [G43708QI] could be generated at this time" }, { "glytoucan_ac": "G43761IQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G86321OX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G43761IQ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G43767FS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53985AY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 }, { "id": "G53985AY", "dp": 11 }, { "id": "G43767FS", "dp": 11 } ], "links": [ { "target": "G43767FS", "source": "G53985AY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53985AY", "source": "G78890OB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43790PG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G43797QQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G32173NW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G43797QQ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G43814TV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G58281SK", "dp": 9 } ], "links": [ { "target": "G43814TV", "source": "G58281SK", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G58281SK", "source": "G59471TH", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43830WV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43830WV] could be generated at this time" }, { "glytoucan_ac": "G43832DJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G16774YZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 }, { "id": "G16774YZ", "dp": 18 }, { "id": "G43832DJ", "dp": 18 } ], "links": [ { "target": "G43832DJ", "source": "G16774YZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16774YZ", "source": "G86696LV", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43839NY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G26018HD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G26018HD", "dp": 12 }, { "id": "G43839NY", "dp": 12 } ], "links": [ { "target": "G43839NY", "source": "G26018HD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26018HD", "source": "G90870DG", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43864TG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43864TG] could be generated at this time" }, { "glytoucan_ac": "G43869EE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G25097RR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 }, { "id": "G25097RR", "dp": 15 }, { "id": "G43869EE", "dp": 15 } ], "links": [ { "target": "G43869EE", "source": "G25097RR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G43873MM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43873MM] could be generated at this time" }, { "glytoucan_ac": "G43981RC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G43981RC] could be generated at this time" }, { "glytoucan_ac": "G43989OI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G68845SP", "dp": 14 }, { "id": "G22079SE", "dp": 15 } ], "links": [ { "target": "G43989OI", "source": "G22079SE", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G22079SE", "source": "G68845SP", "residue_affected": { "residue_id": "N48", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G68845SP", "source": "G18938DW", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44005DK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G44005DK] could be generated at this time" }, { "glytoucan_ac": "G44027TT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31532GK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 }, { "id": "G03895SR", "dp": 15 }, { "id": "G09118YK", "dp": 16 }, { "id": "G31532GK", "dp": 17 }, { "id": "G44027TT", "dp": 17 } ], "links": [ { "target": "G44027TT", "source": "G31532GK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31532GK", "source": "G09118YK", "residue_affected": { "residue_id": "N108", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G09118YK", "source": "G03895SR", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G03895SR", "source": "G16150CJ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44030BX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G33802UM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44030BX", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G44043ZX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90130AG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44043ZX", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G44046WQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74090KZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G74090KZ", "dp": 7 }, { "id": "G44046WQ", "dp": 7 } ], "links": [ { "target": "G44046WQ", "source": "G74090KZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74090KZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44073EJ", "notes": [], "error": "No pathways for [G44073EJ] could be generated at this time" }, { "glytoucan_ac": "G44079HZ", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G06195HM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G04214MY", "dp": 11 }, { "id": "G06195HM", "dp": 12 }, { "id": "G44079HZ", "dp": 12 } ], "links": [ { "target": "G44079HZ", "source": "G06195HM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06195HM", "source": "G04214MY", "residue_affected": { "residue_id": "N237", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04214MY", "source": "G28826SH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44092XR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G99411XJ", "dp": 14 } ], "links": [ { "target": "G44092XR", "source": "G99411XJ", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99411XJ", "source": "G92359VA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44137YR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49446SO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44137YR", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G44151FI", "notes": [], "error": "No pathways for [G44151FI] could be generated at this time" }, { "glytoucan_ac": "G44152CO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 } ], "links": [ { "target": "G44152CO", "source": "G66866LE", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44182FH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G45660WC", "dp": 12 } ], "links": [ { "target": "G44182FH", "source": "G45660WC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G45660WC", "source": "G99645NK", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44201QD", "notes": [], "error": "No pathways for [G44201QD] could be generated at this time" }, { "glytoucan_ac": "G44202NB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G72821WX", "dp": 9 } ], "links": [ { "target": "G44202NB", "source": "G72821WX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72821WX", "source": "G12398HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44210FS", "notes": [], "error": "No pathways for [G44210FS] could be generated at this time" }, { "glytoucan_ac": "G44223QP", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G44223QP] could be generated at this time" }, { "glytoucan_ac": "G44264DI", "notes": [], "error": "No pathways for [G44264DI] could be generated at this time" }, { "glytoucan_ac": "G44325XR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G89168LM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G89168LM", "dp": 15 }, { "id": "G44325XR", "dp": 15 } ], "links": [ { "target": "G44325XR", "source": "G89168LM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89168LM", "source": "G63889NK", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44327JQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G86357DX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G44327JQ", "dp": 12 } ], "links": [ { "target": "G44327JQ", "source": "G86357DX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44339HI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 } ], "links": [ { "target": "G44339HI", "source": "G31010RQ", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44361OH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96503EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44361OH", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G44364RM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53667CH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44364RM", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G44414DH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G44504SC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G44504SC", "source": "G20030CU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44510KF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G87535DG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 }, { "id": "G87535DG", "dp": 12 }, { "id": "G44510KF", "dp": 12 } ], "links": [ { "target": "G44510KF", "source": "G87535DG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G87535DG", "source": "G74675FC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44515AZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40027VO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44515AZ", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G44541JO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90017UO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G44541JO", "dp": 10 } ], "links": [ { "target": "G44541JO", "source": "G90017UO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44598QA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G22388FD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44598QA", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G44617UT", "notes": [], "error": "No pathways for [G44617UT] could be generated at this time" }, { "glytoucan_ac": "G44618FI", "notes": [], "error": "No pathways for [G44618FI] could be generated at this time" }, { "glytoucan_ac": "G44623TX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 } ], "links": [ { "target": "G44623TX", "source": "G79809MM", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44639PM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82847HG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44639PM", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G44656CN", "notes": [], "error": "No pathways for [G44656CN] could be generated at this time" }, { "glytoucan_ac": "G44688UB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75972ZC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44688UB", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G44723YJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G02311IE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G44723YJ", "dp": 16 } ], "links": [ { "target": "G44723YJ", "source": "G02311IE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44743IQ", "notes": [], "error": "No pathways for [G44743IQ] could be generated at this time" }, { "glytoucan_ac": "G44747CU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16828VN]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G44747CU", "dp": 9 } ], "links": [ { "target": "G44747CU", "source": "G16828VN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44754DF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89993FE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G44754DF", "dp": 8 } ], "links": [ { "target": "G44754DF", "source": "G89993FE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44770ZI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88461FF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G44770ZI", "dp": 9 } ], "links": [ { "target": "G44770ZI", "source": "G88461FF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44790NU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G44790NU] could be generated at this time" }, { "glytoucan_ac": "G44792ZH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 } ], "links": [ { "target": "G44792ZH", "source": "G26182BM", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44799JP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19868AX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G19868AX", "dp": 8 }, { "id": "G44799JP", "dp": 8 } ], "links": [ { "target": "G44799JP", "source": "G19868AX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19868AX", "source": "G39213VZ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44809MP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G44825LU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G84879CH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G44825LU", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G44825QL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G44826KU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G45560HM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G44826KU", "dp": 10 } ], "links": [ { "target": "G44826KU", "source": "G45560HM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44845VH", "notes": [], "error": "No pathways for [G44845VH] could be generated at this time" }, { "glytoucan_ac": "G44865OQ", "notes": [], "error": "No pathways for [G44865OQ] could be generated at this time" }, { "glytoucan_ac": "G44904UE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G44904UE] could be generated at this time" }, { "glytoucan_ac": "G44909WI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56748EO]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G56748EO", "dp": 10 }, { "id": "G44909WI", "dp": 10 } ], "links": [ { "target": "G44909WI", "source": "G56748EO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44946WH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 } ], "links": [ { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G44962ZM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30514JJ]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G44962ZM", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G44974AB", "notes": [], "error": "No pathways for [G44974AB] could be generated at this time" }, { "glytoucan_ac": "G44982DH", "notes": [], "error": "No pathways for [G44982DH] could be generated at this time" }, { "glytoucan_ac": "G44992KB", "notes": [], "error": "No pathways for [G44992KB] could be generated at this time" }, { "glytoucan_ac": "G44996SV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72698LT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G82861UH", "dp": 9 }, { "id": "G72698LT", "dp": 10 }, { "id": "G44996SV", "dp": 10 } ], "links": [ { "target": "G44996SV", "source": "G72698LT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72698LT", "source": "G82861UH", "residue_affected": { "residue_id": "N32", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G82861UH", "source": "G59471TH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45000ZN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G23419AQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45000ZN", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G45036WQ", "notes": [], "error": "No pathways for [G45036WQ] could be generated at this time" }, { "glytoucan_ac": "G45048TZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G45048TZ] could be generated at this time" }, { "glytoucan_ac": "G45058LS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G40358EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G40358EZ", "dp": 11 }, { "id": "G45058LS", "dp": 11 } ], "links": [ { "target": "G45058LS", "source": "G40358EZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40358EZ", "source": "G00176HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45073MO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 } ], "links": [ { "target": "G45073MO", "source": "G84376FR", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45104SZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20885BK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45104SZ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G45108QT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91832SW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 }, { "id": "G91832SW", "dp": 14 }, { "id": "G45108QT", "dp": 14 } ], "links": [ { "target": "G45108QT", "source": "G91832SW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91832SW", "source": "G85085MS", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45155FK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G44504SC", "dp": 10 } ], "links": [ { "target": "G45155FK", "source": "G44504SC", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G44504SC", "source": "G20030CU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45187EI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 } ], "links": [ { "target": "G45187EI", "source": "G08577ZR", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45201FL", "notes": [], "error": "No pathways for [G45201FL] could be generated at this time" }, { "glytoucan_ac": "G45209NR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 } ], "links": [ { "target": "G45209NR", "source": "G91905FJ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45217YN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54986EB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45217YN", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G45229AI", "notes": [], "error": "No pathways for [G45229AI] could be generated at this time" }, { "glytoucan_ac": "G45250VC", "notes": [], "error": "No pathways for [G45250VC] could be generated at this time" }, { "glytoucan_ac": "G45256SO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93500PH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G45256SO", "dp": 9 } ], "links": [ { "target": "G45256SO", "source": "G93500PH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45258LH", "notes": [], "error": "No pathways for [G45258LH] could be generated at this time" }, { "glytoucan_ac": "G45262QY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 } ], "links": [ { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45264AM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 } ], "links": [ { "target": "G45264AM", "source": "G88461FF", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45325UV", "notes": [], "error": "No pathways for [G45325UV] could be generated at this time" }, { "glytoucan_ac": "G45332CP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G07699XI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 }, { "id": "G07699XI", "dp": 11 }, { "id": "G45332CP", "dp": 11 } ], "links": [ { "target": "G45332CP", "source": "G07699XI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07699XI", "source": "G78155FK", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45358WU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G99770NO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G15103WJ", "dp": 12 }, { "id": "G99770NO", "dp": 13 }, { "id": "G45358WU", "dp": 13 } ], "links": [ { "target": "G45358WU", "source": "G99770NO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99770NO", "source": "G15103WJ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G15103WJ", "source": "G25520XG", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45359RY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 } ], "links": [ { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45365RV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G45365RV", "source": "G46638GC", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45374ZW", "notes": [], "error": "No pathways for [G45374ZW] could be generated at this time" }, { "glytoucan_ac": "G45420PL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96235XM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45420PL", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G45492BK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G45533OY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G79556AB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G79556AB", "dp": 12 }, { "id": "G45533OY", "dp": 12 } ], "links": [ { "target": "G45533OY", "source": "G79556AB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79556AB", "source": "G82252QI", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45560HM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 } ], "links": [ { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45573QR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G16956YO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45573QR", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G45574NI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G45581BY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G70830AN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45581BY", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G45598BE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G11041DA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G45598BE", "dp": 11 } ], "links": [ { "target": "G45598BE", "source": "G11041DA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45603BW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 } ], "links": [ { "target": "G45603BW", "source": "G56549DH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45629TR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G01669LU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G45629TR", "dp": 12 } ], "links": [ { "target": "G45629TR", "source": "G01669LU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45660WC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 } ], "links": [ { "target": "G45660WC", "source": "G99645NK", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45664QZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 } ], "links": [ { "target": "G45664QZ", "source": "G81432SH", "residue_affected": { "residue_id": "N216", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45686NF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G62880PC", "dp": 9 } ], "links": [ { "target": "G45686NF", "source": "G62880PC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62880PC", "source": "G59471TH", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45720CA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 } ], "links": [ { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45747TC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06635WE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45747TC", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G45776ET", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78648QN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45776ET", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G45777DE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G26939ZY", "dp": 8 } ], "links": [ { "target": "G45777DE", "source": "G26939ZY", "residue_affected": { "residue_id": "N305", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G26939ZY", "source": "G39213VZ", "residue_affected": { "residue_id": "N306", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45826PJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47108UC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G47108UC", "dp": 9 }, { "id": "G45826PJ", "dp": 9 } ], "links": [ { "target": "G45826PJ", "source": "G47108UC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47108UC", "source": "G80858MF", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45832UN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 }, { "id": "G05546WG", "dp": 9 } ], "links": [ { "target": "G45832UN", "source": "G05546WG", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G05546WG", "source": "G69812OF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G45844BS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36316RB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G45844BS", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G45882CQ", "notes": [], "error": "No pathways for [G45882CQ] could be generated at this time" }, { "glytoucan_ac": "G45888VL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G45889JQ", "notes": [], "error": "No pathways for [G45889JQ] could be generated at this time" }, { "glytoucan_ac": "G45995IV", "notes": [], "error": "No pathways for [G45995IV] could be generated at this time" }, { "glytoucan_ac": "G45997JW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G45187EI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G45187EI", "dp": 11 }, { "id": "G45997JW", "dp": 11 } ], "links": [ { "target": "G45997JW", "source": "G45187EI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45187EI", "source": "G08577ZR", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46021KV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G46021KV", "source": "G29857RC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46031NV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G11041DA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G46031NV", "dp": 11 } ], "links": [ { "target": "G46031NV", "source": "G11041DA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46038XL", "notes": [], "error": "No pathways for [G46038XL] could be generated at this time" }, { "glytoucan_ac": "G46103YX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G50364FV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G46103YX", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G46108US", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17964DY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G46108US", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G46123YD", "notes": [], "error": "No pathways for [G46123YD] could be generated at this time" }, { "glytoucan_ac": "G46141DD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43702IX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 }, { "id": "G43702IX", "dp": 15 }, { "id": "G46141DD", "dp": 15 } ], "links": [ { "target": "G46141DD", "source": "G43702IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43702IX", "source": "G23616ZX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46152KR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23142YD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G84852GW", "dp": 9 }, { "id": "G23142YD", "dp": 10 }, { "id": "G46152KR", "dp": 10 } ], "links": [ { "target": "G46152KR", "source": "G23142YD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23142YD", "source": "G84852GW", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G84852GW", "source": "G12398HZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46185ND", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 } ], "links": [ { "target": "G46185ND", "source": "G53752TA", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46213JU", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G46213JU", "source": "G16828VN", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46260CP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25471TG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G46260CP", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G46264GY", "notes": [], "error": "No pathways for [G46264GY] could be generated at this time" }, { "glytoucan_ac": "G46298TE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G23616ZX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 }, { "id": "G46298TE", "dp": 14 } ], "links": [ { "target": "G46298TE", "source": "G23616ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46308WD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G11637WL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G46308WD", "dp": 10 } ], "links": [ { "target": "G46308WD", "source": "G11637WL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46314PI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 } ], "links": [ { "target": "G46314PI", "source": "G27123NH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46355PL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G31637BB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G46355PL", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G46387UV", "notes": [], "error": "No pathways for [G46387UV] could be generated at this time" }, { "glytoucan_ac": "G46394FV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G86005HP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 }, { "id": "G25097RR", "dp": 15 }, { "id": "G86005HP", "dp": 16 }, { "id": "G46394FV", "dp": 16 } ], "links": [ { "target": "G46394FV", "source": "G86005HP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86005HP", "source": "G25097RR", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46406BL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G46406BL", "source": "G11041DA", "residue_affected": { "residue_id": "N276", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46407AA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G02582JY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G30901GC", "dp": 9 }, { "id": "G02582JY", "dp": 10 }, { "id": "G46407AA", "dp": 10 } ], "links": [ { "target": "G46407AA", "source": "G02582JY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02582JY", "source": "G30901GC", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30901GC", "source": "G79348ZY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46412RZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G46415RP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G77974XY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77974XY", "dp": 10 }, { "id": "G46415RP", "dp": 10 } ], "links": [ { "target": "G46415RP", "source": "G77974XY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77974XY", "source": "G20030CU", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46425HN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 } ], "links": [ { "target": "G46425HN", "source": "G45720CA", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46432HW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39595CR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G39595CR", "dp": 14 }, { "id": "G46432HW", "dp": 14 } ], "links": [ { "target": "G46432HW", "source": "G39595CR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39595CR", "source": "G80294GH", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46449AK", "notes": [], "error": "No pathways for [G46449AK] could be generated at this time" }, { "glytoucan_ac": "G46470AD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 } ], "links": [ { "target": "G46470AD", "source": "G01856RL", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46479GT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G85208SY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G46479GT", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G46491JP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G37597FW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 }, { "id": "G46491JP", "dp": 13 } ], "links": [ { "target": "G46491JP", "source": "G37597FW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46503KK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 } ], "links": [ { "target": "G46503KK", "source": "G18219CJ", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46511PG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G62883YA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 }, { "id": "G62883YA", "dp": 11 }, { "id": "G46511PG", "dp": 11 } ], "links": [ { "target": "G46511PG", "source": "G62883YA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62883YA", "source": "G66866LE", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46542RN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G68845SP", "dp": 14 } ], "links": [ { "target": "G46542RN", "source": "G68845SP", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G68845SP", "source": "G18938DW", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46560SM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82853YO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G46560SM", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G46638GC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 } ], "links": [ { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46654QM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 } ], "links": [ { "target": "G46654QM", "source": "G91023GB", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46661UU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G73817GH", "dp": 10 }, { "id": "G57601AP", "dp": 11 }, { "id": "G11615SW", "dp": 12 } ], "links": [ { "target": "G46661UU", "source": "G11615SW", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G11615SW", "source": "G57601AP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G57601AP", "source": "G73817GH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46712PI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G46712PI", "source": "G00176HZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46763GM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G46767VX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G46767VX] could be generated at this time" }, { "glytoucan_ac": "G46836GH", "notes": [], "error": "No pathways for [G46836GH] could be generated at this time" }, { "glytoucan_ac": "G46945LQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G46991EQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86005HP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 }, { "id": "G25097RR", "dp": 15 }, { "id": "G86005HP", "dp": 16 }, { "id": "G46991EQ", "dp": 16 } ], "links": [ { "target": "G46991EQ", "source": "G86005HP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86005HP", "source": "G25097RR", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G46998LN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G01856RL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 }, { "id": "G46998LN", "dp": 10 } ], "links": [ { "target": "G46998LN", "source": "G01856RL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47006SF", "notes": [], "error": "No pathways for [G47006SF] could be generated at this time" }, { "glytoucan_ac": "G47007PV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G47007PV] could be generated at this time" }, { "glytoucan_ac": "G47011KD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 } ], "links": [ { "target": "G47011KD", "source": "G34527RW", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47031UJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 } ], "links": [ { "target": "G47031UJ", "source": "G71679MX", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47043LK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G83738AG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G47043LK", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G47065QM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G40707SF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G47065QM", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G47108UC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 } ], "links": [ { "target": "G47108UC", "source": "G80858MF", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47171PS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82140BL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G08709JB", "dp": 13 }, { "id": "G82140BL", "dp": 14 }, { "id": "G47171PS", "dp": 14 } ], "links": [ { "target": "G47171PS", "source": "G82140BL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82140BL", "source": "G08709JB", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G08709JB", "source": "G45359RY", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47171PW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88321DT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 }, { "id": "G88321DT", "dp": 15 }, { "id": "G47171PW", "dp": 15 } ], "links": [ { "target": "G47171PW", "source": "G88321DT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88321DT", "source": "G53485VW", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47175EF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47179RN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53168IY]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [G53168IY] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G47206MY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30553WH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G30553WH", "dp": 9 }, { "id": "G47206MY", "dp": 9 } ], "links": [ { "target": "G47206MY", "source": "G30553WH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30553WH", "source": "G20956ZK", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47273WV", "notes": [], "error": "No pathways for [G47273WV] could be generated at this time" }, { "glytoucan_ac": "G47279LF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G47279LF] could be generated at this time" }, { "glytoucan_ac": "G47280HM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 } ], "links": [ { "target": "G47280HM", "source": "G41611UP", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47379VH", "notes": [], "error": "No pathways for [G47379VH] could be generated at this time" }, { "glytoucan_ac": "G47384NK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G47384NK] could be generated at this time" }, { "glytoucan_ac": "G47407FC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98117HW]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G47407FC", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G47427YD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94394GK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G47427YD", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G47456CG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G94679TQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G47456CG", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G47498FQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51367TM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G47498FQ", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G47519VR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G47519VR] could be generated at this time" }, { "glytoucan_ac": "G47531XE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60215UL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G47175EF", "dp": 11 }, { "id": "G60215UL", "dp": 12 }, { "id": "G47531XE", "dp": 12 } ], "links": [ { "target": "G47531XE", "source": "G60215UL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60215UL", "source": "G47175EF", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47554EG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G47554EG] could be generated at this time" }, { "glytoucan_ac": "G47566FL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G47566FL", "source": "G07483YN", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47596RR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G47606XQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G26320VO", "dp": 10 } ], "links": [ { "target": "G47606XQ", "source": "G26320VO", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26320VO", "source": "G58667NI", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47645YK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G47675LW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34527RW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G47675LW", "dp": 8 } ], "links": [ { "target": "G47675LW", "source": "G34527RW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47741BL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75120WS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G47741BL", "dp": 13 } ], "links": [ { "target": "G47741BL", "source": "G75120WS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47756FE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11953VE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G47756FE", "dp": 14 } ], "links": [ { "target": "G47756FE", "source": "G11953VE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47766VH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30901GC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G30901GC", "dp": 9 }, { "id": "G47766VH", "dp": 9 } ], "links": [ { "target": "G47766VH", "source": "G30901GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30901GC", "source": "G79348ZY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47782UT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 } ], "links": [ { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47816DI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G53752TA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G47816DI", "dp": 11 } ], "links": [ { "target": "G47816DI", "source": "G53752TA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47822QX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 } ], "links": [ { "target": "G47822QX", "source": "G16759KR", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47859DD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G33742YO", "dp": 9 } ], "links": [ { "target": "G47859DD", "source": "G33742YO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47866EC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G56340GX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G56340GX", "dp": 10 }, { "id": "G47866EC", "dp": 10 } ], "links": [ { "target": "G47866EC", "source": "G56340GX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56340GX", "source": "G27919IH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47877IZ", "notes": [], "error": "No pathways for [G47877IZ] could be generated at this time" }, { "glytoucan_ac": "G47911PU", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G47925EV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82252QI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G47925EV", "dp": 11 } ], "links": [ { "target": "G47925EV", "source": "G82252QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47936PQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G25520XG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G47936PQ", "dp": 11 } ], "links": [ { "target": "G47936PQ", "source": "G25520XG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47961DI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91905FJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G47961DI", "dp": 14 } ], "links": [ { "target": "G47961DI", "source": "G91905FJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47963XB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 } ], "links": [ { "target": "G47963XB", "source": "G66282NU", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G47975JA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G47975JA", "source": "G11041DA", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48020LQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90348RI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G90348RI", "dp": 12 }, { "id": "G48020LQ", "dp": 12 } ], "links": [ { "target": "G48020LQ", "source": "G90348RI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90348RI", "source": "G11041DA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48040FY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77812KJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G48040FY", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G48069JX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G48069JX] could be generated at this time" }, { "glytoucan_ac": "G48109OV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G48109OV] could be generated at this time" }, { "glytoucan_ac": "G48148JS", "notes": [], "error": "No pathways for [G48148JS] could be generated at this time" }, { "glytoucan_ac": "G48148UW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G50730KL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G50730KL", "dp": 9 }, { "id": "G48148UW", "dp": 9 } ], "links": [ { "target": "G48148UW", "source": "G50730KL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50730KL", "source": "G08520NM", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G48168SI", "notes": [], "error": "No pathways for [G48168SI] could be generated at this time" }, { "glytoucan_ac": "G48185FI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53985AY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 }, { "id": "G53985AY", "dp": 11 }, { "id": "G48185FI", "dp": 11 } ], "links": [ { "target": "G48185FI", "source": "G53985AY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53985AY", "source": "G78890OB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48205IY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G04783EJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G48205IY", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G48277OH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 } ], "links": [ { "target": "G48277OH", "source": "G19726AG", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48288NV", "notes": [], "error": "No pathways for [G48288NV] could be generated at this time" }, { "glytoucan_ac": "G48329CR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G48329CR] could be generated at this time" }, { "glytoucan_ac": "G48330KH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G51768ZH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G48330KH", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G48350AZ", "notes": [], "error": "No pathways for [G48350AZ] could be generated at this time" }, { "glytoucan_ac": "G48369JO", "notes": [], "error": "No pathways for [G48369JO] could be generated at this time" }, { "glytoucan_ac": "G48405LH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50730KL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G50730KL", "dp": 9 }, { "id": "G48405LH", "dp": 9 } ], "links": [ { "target": "G48405LH", "source": "G50730KL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50730KL", "source": "G08520NM", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G48421GV", "notes": [], "error": "No pathways for [G48421GV] could be generated at this time" }, { "glytoucan_ac": "G48442VP", "notes": [], "error": "No pathways for [G48442VP] could be generated at this time" }, { "glytoucan_ac": "G48468PF", "notes": [], "error": "No pathways for [G48468PF] could be generated at this time" }, { "glytoucan_ac": "G48488XT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G96963QG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G96963QG", "dp": 12 }, { "id": "G48488XT", "dp": 12 } ], "links": [ { "target": "G48488XT", "source": "G96963QG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48527XN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G33608TH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G48527XN", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G48595FA", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G52302PL]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G48595FA", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G48616UI", "notes": [], "error": "No pathways for [G48616UI] could be generated at this time" }, { "glytoucan_ac": "G48630BP", "notes": [], "error": "No pathways for [G48630BP] could be generated at this time" }, { "glytoucan_ac": "G48658CL", "notes": [], "error": "No pathways for [G48658CL] could be generated at this time" }, { "glytoucan_ac": "G48658PB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 } ], "links": [ { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48698GX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G48713OY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14127XU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G14127XU", "dp": 13 }, { "id": "G48713OY", "dp": 13 } ], "links": [ { "target": "G48713OY", "source": "G14127XU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14127XU", "source": "G91023GB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48753IC", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G48753IC] could be generated at this time" }, { "glytoucan_ac": "G48767NV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 } ], "links": [ { "target": "G48767NV", "source": "G53812BX", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48802KI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 } ], "links": [ { "target": "G48802KI", "source": "G43677TG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48809ZO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38637SA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G48809ZO", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G48822BJ", "notes": [], "error": "No pathways for [G48822BJ] could be generated at this time" }, { "glytoucan_ac": "G48860TK", "notes": [], "error": "No pathways for [G48860TK] could be generated at this time" }, { "glytoucan_ac": "G48879CK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G48882DX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G99943EE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G48882DX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G48886SH", "notes": [], "error": "No pathways for [G48886SH] could be generated at this time" }, { "glytoucan_ac": "G48945UO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 } ], "links": [ { "target": "G48945UO", "source": "G32305RZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48954CA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G48954CA", "source": "G12398HZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G48980RC", "notes": [], "error": "No pathways for [G48980RC] could be generated at this time" }, { "glytoucan_ac": "G49009JI", "notes": [], "error": "No pathways for [G49009JI] could be generated at this time" }, { "glytoucan_ac": "G49022RM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G49022RM] could be generated at this time" }, { "glytoucan_ac": "G49053WC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G74859XI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G49053WC", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G49084JY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G49096WS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G28550OD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G28550OD", "dp": 9 }, { "id": "G49096WS", "dp": 9 } ], "links": [ { "target": "G49096WS", "source": "G28550OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28550OD", "source": "G12398HZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49104KI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G44504SC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G44504SC", "dp": 10 }, { "id": "G49104KI", "dp": 10 } ], "links": [ { "target": "G49104KI", "source": "G44504SC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44504SC", "source": "G20030CU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49130JL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G29112GC", "dp": 10 }, { "id": "G72060AW", "dp": 11 } ], "links": [ { "target": "G49130JL", "source": "G72060AW", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G72060AW", "source": "G29112GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29112GC", "source": "G20030CU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49168NM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94490EL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G49168NM", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G49225WK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59655SA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G59655SA", "dp": 12 }, { "id": "G49225WK", "dp": 12 } ], "links": [ { "target": "G49225WK", "source": "G59655SA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59655SA", "source": "G53752TA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49232RW", "notes": [], "error": "No pathways for [G49232RW] could be generated at this time" }, { "glytoucan_ac": "G49235GA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G80537QW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G80537QW", "dp": 14 }, { "id": "G49235GA", "dp": 14 } ], "links": [ { "target": "G49235GA", "source": "G80537QW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80537QW", "source": "G93582HM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49280JI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G33262YZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G33262YZ", "dp": 11 }, { "id": "G49280JI", "dp": 11 } ], "links": [ { "target": "G49280JI", "source": "G33262YZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33262YZ", "source": "G52934AK", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49282JI", "notes": [], "error": "No pathways for [G49282JI] could be generated at this time" }, { "glytoucan_ac": "G49299ZV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G49305IN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 } ], "links": [ { "target": "G49305IN", "source": "G86696LV", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49307MQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G78276SQ", "dp": 12 } ], "links": [ { "target": "G49307MQ", "source": "G78276SQ", "residue_affected": { "residue_id": "N408", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G78276SQ", "source": "G11041DA", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49357ZK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G13592VY", "dp": 8 } ], "links": [ { "target": "G49357ZK", "source": "G13592VY", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G13592VY", "source": "G69411IG", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49369WH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00176HZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G49369WH", "dp": 10 } ], "links": [ { "target": "G49369WH", "source": "G00176HZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49383JW", "notes": [], "error": "No pathways for [G49383JW] could be generated at this time" }, { "glytoucan_ac": "G49401CB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G67215MI]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G67215MI", "dp": 11 }, { "id": "G49401CB", "dp": 11 } ], "links": [ { "target": "G49401CB", "source": "G67215MI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G67215MI", "source": "G11637WL", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49401NP", "notes": [], "error": "No pathways for [G49401NP] could be generated at this time" }, { "glytoucan_ac": "G49401WK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 }, { "id": "G88426SE", "dp": 11 } ], "links": [ { "target": "G49401WK", "source": "G88426SE", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G88426SE", "source": "G78155FK", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49440XK", "notes": [], "error": "No pathways for [G49440XK] could be generated at this time" }, { "glytoucan_ac": "G49446SO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G49446SO] could be generated at this time" }, { "glytoucan_ac": "G49481UE", "notes": [], "error": "No pathways for [G49481UE] could be generated at this time" }, { "glytoucan_ac": "G49495MH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90987JA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G49495MH", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G49495US", "notes": [], "error": "No pathways for [G49495US] could be generated at this time" }, { "glytoucan_ac": "G49503QY", "notes": [], "error": "No pathways for [G49503QY] could be generated at this time" }, { "glytoucan_ac": "G49504OJ", "notes": [], "error": "No pathways for [G49504OJ] could be generated at this time" }, { "glytoucan_ac": "G49515VE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49544FY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78885XB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G49544FY", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G49562JB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G01669LU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G49562JB", "dp": 12 } ], "links": [ { "target": "G49562JB", "source": "G01669LU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49580XQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06969ZX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 }, { "id": "G49580XQ", "dp": 10 } ], "links": [ { "target": "G49580XQ", "source": "G06969ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49582YX", "notes": [], "error": "No pathways for [G49582YX] could be generated at this time" }, { "glytoucan_ac": "G49585QR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G21246OH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G21246OH", "dp": 11 }, { "id": "G49585QR", "dp": 11 } ], "links": [ { "target": "G49585QR", "source": "G21246OH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21246OH", "source": "G00176HZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49601RS", "notes": [], "error": "No pathways for [G49601RS] could be generated at this time" }, { "glytoucan_ac": "G49616WZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91199QX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G49616WZ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G49664YG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88417ED]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G49664YG", "dp": 10 } ], "links": [ { "target": "G49664YG", "source": "G88417ED", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49721VX", "notes": [], "error": "No pathways for [G49721VX] could be generated at this time" }, { "glytoucan_ac": "G49743VF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G06216UH", "dp": 10 } ], "links": [ { "target": "G49743VF", "source": "G06216UH", "residue_affected": { "residue_id": "N470", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49785PR", "notes": [], "error": "No pathways for [G49785PR] could be generated at this time" }, { "glytoucan_ac": "G49800TU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G54260SD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G49800TU", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G49827WK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 } ], "links": [ { "target": "G49827WK", "source": "G09446VC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G49832FF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G92848CF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G49832FF", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G49840MH", "notes": [], "error": "No pathways for [G49840MH] could be generated at this time" }, { "glytoucan_ac": "G49915LA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G49915LA] could be generated at this time" }, { "glytoucan_ac": "G49923GC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G76807JB]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G49923GC", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G49930HB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99603GB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 }, { "id": "G99603GB", "dp": 9 }, { "id": "G49930HB", "dp": 9 } ], "links": [ { "target": "G49930HB", "source": "G99603GB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99603GB", "source": "G64669AQ", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G49933AX", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G49933AX] could be generated at this time" }, { "glytoucan_ac": "G49935CA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21459ST]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G49935CA", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G49951NR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99370TQ]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G49951NR", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G49961MS", "notes": [], "error": "No pathways for [G49961MS] could be generated at this time" }, { "glytoucan_ac": "G49961XO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G50013XL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G23546LY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G50013XL", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G50023BR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G50023BR] could be generated at this time" }, { "glytoucan_ac": "G50068PO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G78011JO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G50068PO", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G50076JD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G79803HS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 }, { "id": "G74438AB", "dp": 12 }, { "id": "G79803HS", "dp": 13 }, { "id": "G50076JD", "dp": 13 } ], "links": [ { "target": "G50076JD", "source": "G79803HS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79803HS", "source": "G74438AB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G74438AB", "source": "G34905OT", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50078RT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 } ], "links": [ { "target": "G50078RT", "source": "G79809MM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50112PT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G05794RZ]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G40806JH", "dp": 11 }, { "id": "G05794RZ", "dp": 12 }, { "id": "G50112PT", "dp": 12 } ], "links": [ { "target": "G50112PT", "source": "G05794RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G05794RZ", "source": "G40806JH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50119EM", "notes": [], "error": "No pathways for [G50119EM] could be generated at this time" }, { "glytoucan_ac": "G50135PA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G50135PA] could be generated at this time" }, { "glytoucan_ac": "G50139IU", "notes": [], "error": "No pathways for [G50139IU] could be generated at this time" }, { "glytoucan_ac": "G50159UX", "notes": [], "error": "No pathways for [G50159UX] could be generated at this time" }, { "glytoucan_ac": "G50165QT", "notes": [], "error": "No pathways for [G50165QT] could be generated at this time" }, { "glytoucan_ac": "G50205RT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G11535IB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G11535IB", "dp": 9 }, { "id": "G50205RT", "dp": 9 } ], "links": [ { "target": "G50205RT", "source": "G11535IB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11535IB", "source": "G59471TH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50211SY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71704AG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G42686NQ", "dp": 14 }, { "id": "G71704AG", "dp": 15 }, { "id": "G50211SY", "dp": 15 } ], "links": [ { "target": "G50211SY", "source": "G71704AG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71704AG", "source": "G42686NQ", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G42686NQ", "source": "G19726AG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50216QG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G36523TZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G36523TZ", "dp": 12 }, { "id": "G50216QG", "dp": 12 } ], "links": [ { "target": "G50216QG", "source": "G36523TZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36523TZ", "source": "G29857RC", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50222RE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G74090KZ", "dp": 7 } ], "links": [ { "target": "G50222RE", "source": "G74090KZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G74090KZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50258QB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86730KO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 }, { "id": "G86730KO", "dp": 13 }, { "id": "G50258QB", "dp": 13 } ], "links": [ { "target": "G50258QB", "source": "G86730KO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86730KO", "source": "G48658PB", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50278HE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G50278HE] could be generated at this time" }, { "glytoucan_ac": "G50343XZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G50364FV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G50364FV] could be generated at this time" }, { "glytoucan_ac": "G50392ZV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 } ], "links": [ { "target": "G50392ZV", "source": "G32201IL", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50398UZ", "notes": [], "error": "No pathways for [G50398UZ] could be generated at this time" }, { "glytoucan_ac": "G50427EN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G42028DN", "dp": 11 }, { "id": "G26264SQ", "dp": 12 } ], "links": [ { "target": "G50427EN", "source": "G26264SQ", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G26264SQ", "source": "G42028DN", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G42028DN", "source": "G09921WG", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50432VO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G50448ZV", "notes": [], "error": "No pathways for [G50448ZV] could be generated at this time" }, { "glytoucan_ac": "G50451XH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G50451XH] could be generated at this time" }, { "glytoucan_ac": "G50462VS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G86696LV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 }, { "id": "G50462VS", "dp": 17 } ], "links": [ { "target": "G50462VS", "source": "G86696LV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50474FI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82420SH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G82420SH", "dp": 10 }, { "id": "G50474FI", "dp": 10 } ], "links": [ { "target": "G50474FI", "source": "G82420SH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82420SH", "source": "G45262QY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50489VC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 } ], "links": [ { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50507PS", "notes": [], "error": "No pathways for [G50507PS] could be generated at this time" }, { "glytoucan_ac": "G50508SG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G57835AK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G50508SG", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G50518XT", "notes": [], "error": "No pathways for [G50518XT] could be generated at this time" }, { "glytoucan_ac": "G50531NJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29026MS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G29026MS", "dp": 12 }, { "id": "G50531NJ", "dp": 12 } ], "links": [ { "target": "G50531NJ", "source": "G29026MS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29026MS", "source": "G59877NF", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50549VU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59300GC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G59300GC", "dp": 14 }, { "id": "G50549VU", "dp": 14 } ], "links": [ { "target": "G50549VU", "source": "G59300GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59300GC", "source": "G73492AT", "residue_affected": { "residue_id": "N78", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50554LM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G90564EX", "dp": 11 }, { "id": "G08949VK", "dp": 12 }, { "id": "G12450CJ", "dp": 13 } ], "links": [ { "target": "G50554LM", "source": "G12450CJ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12450CJ", "source": "G08949VK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G08949VK", "source": "G90564EX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90564EX", "source": "G28826SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50638US", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G90825UM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 }, { "id": "G90825UM", "dp": 11 }, { "id": "G50638US", "dp": 11 } ], "links": [ { "target": "G50638US", "source": "G90825UM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90825UM", "source": "G01856RL", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50659JL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G50660UT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G50706US", "notes": [], "error": "No pathways for [G50706US] could be generated at this time" }, { "glytoucan_ac": "G50730KL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G50730KL", "source": "G08520NM", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G50774CV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 } ], "links": [ { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50775RM", "notes": [], "error": "No pathways for [G50775RM] could be generated at this time" }, { "glytoucan_ac": "G50779LX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 } ], "links": [ { "target": "G50779LX", "source": "G25140TA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50782HI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66129DI]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G03275SD", "dp": 10 }, { "id": "G66129DI", "dp": 11 }, { "id": "G50782HI", "dp": 11 } ], "links": [ { "target": "G50782HI", "source": "G66129DI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66129DI", "source": "G03275SD", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50782LR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G91905FJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G50782LR", "dp": 14 } ], "links": [ { "target": "G50782LR", "source": "G91905FJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50829CY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G76478FT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G76478FT", "dp": 11 }, { "id": "G50829CY", "dp": 11 } ], "links": [ { "target": "G50829CY", "source": "G76478FT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76478FT", "source": "G78059CC", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50837EH", "notes": [], "error": "No pathways for [G50837EH] could be generated at this time" }, { "glytoucan_ac": "G50842MS", "notes": [], "error": "No pathways for [G50842MS] could be generated at this time" }, { "glytoucan_ac": "G50846BW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26255AN]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G26274XD", "dp": 11 }, { "id": "G26255AN", "dp": 12 }, { "id": "G50846BW", "dp": 12 } ], "links": [ { "target": "G50846BW", "source": "G26255AN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26255AN", "source": "G26274XD", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G26274XD", "source": "G08187GM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50880EE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10664FL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G10664FL", "dp": 10 }, { "id": "G50880EE", "dp": 10 } ], "links": [ { "target": "G50880EE", "source": "G10664FL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10664FL", "source": "G45262QY", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50915WK", "notes": [], "error": "No pathways for [G50915WK] could be generated at this time" }, { "glytoucan_ac": "G50933UG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76075NA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G76075NA", "dp": 12 }, { "id": "G50933UG", "dp": 12 } ], "links": [ { "target": "G50933UG", "source": "G76075NA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76075NA", "source": "G90870DG", "residue_affected": { "residue_id": "N62", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50943ZX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 } ], "links": [ { "target": "G50943ZX", "source": "G20956ZK", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G50997KD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G86095OE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G75237SS", "dp": 16 }, { "id": "G86095OE", "dp": 17 }, { "id": "G50997KD", "dp": 17 } ], "links": [ { "target": "G50997KD", "source": "G86095OE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86095OE", "source": "G75237SS", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51018GI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G51018GI] could be generated at this time" }, { "glytoucan_ac": "G51050LD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G51050LD] could be generated at this time" }, { "glytoucan_ac": "G51066TO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 } ], "links": [ { "target": "G51066TO", "source": "G10733HY", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51074KT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G51086FE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G65867II]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51086FE", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G51098AA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G51098AA] could be generated at this time" }, { "glytoucan_ac": "G51119RL", "notes": [], "error": "No pathways for [G51119RL] could be generated at this time" }, { "glytoucan_ac": "G51122PB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G16451PE", "dp": 11 } ], "links": [ { "target": "G51122PB", "source": "G16451PE", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G16451PE", "source": "G62504BU", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51168MK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G51175PR", "notes": [], "error": "No pathways for [G51175PR] could be generated at this time" }, { "glytoucan_ac": "G51212OK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17465IO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51212OK", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G51274LI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76528ZS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G76528ZS", "dp": 11 }, { "id": "G51274LI", "dp": 11 } ], "links": [ { "target": "G51274LI", "source": "G76528ZS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76528ZS", "source": "G52934AK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51304JG", "notes": [], "error": "No pathways for [G51304JG] could be generated at this time" }, { "glytoucan_ac": "G51333KM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50427EN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G42028DN", "dp": 11 }, { "id": "G26264SQ", "dp": 12 }, { "id": "G50427EN", "dp": 13 }, { "id": "G51333KM", "dp": 13 } ], "links": [ { "target": "G51333KM", "source": "G50427EN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50427EN", "source": "G26264SQ", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G26264SQ", "source": "G42028DN", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G42028DN", "source": "G09921WG", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51367TM", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G51367TM] could be generated at this time" }, { "glytoucan_ac": "G51378TN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G73817GH", "dp": 10 } ], "links": [ { "target": "G51378TN", "source": "G73817GH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51419BH", "notes": [], "error": "No pathways for [G51419BH] could be generated at this time" }, { "glytoucan_ac": "G51472TJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G11010AN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51472TJ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G51490BW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51508GQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G01935FK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01935FK", "dp": 10 }, { "id": "G51508GQ", "dp": 10 } ], "links": [ { "target": "G51508GQ", "source": "G01935FK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01935FK", "source": "G36191CD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51562OR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G51562OR] could be generated at this time" }, { "glytoucan_ac": "G51601CL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G71812IK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G71812IK", "dp": 9 }, { "id": "G51601CL", "dp": 9 } ], "links": [ { "target": "G51601CL", "source": "G71812IK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71812IK", "source": "G80858MF", "residue_affected": { "residue_id": "N322", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51624KI", "notes": [], "error": "No pathways for [G51624KI] could be generated at this time" }, { "glytoucan_ac": "G51654CU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57092OJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G57092OJ", "dp": 10 }, { "id": "G51654CU", "dp": 10 } ], "links": [ { "target": "G51654CU", "source": "G57092OJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57092OJ", "source": "G58667NI", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51657FI", "notes": [], "error": "No pathways for [G51657FI] could be generated at this time" }, { "glytoucan_ac": "G51670CS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G90870DG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G51670CS", "dp": 11 } ], "links": [ { "target": "G51670CS", "source": "G90870DG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51677OC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27783SY]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G51677OC", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G51688VK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95956WE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G42548XF", "dp": 7 }, { "id": "G95956WE", "dp": 8 }, { "id": "G51688VK", "dp": 8 } ], "links": [ { "target": "G51688VK", "source": "G95956WE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95956WE", "source": "G42548XF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42548XF", "source": "G61751GZ", "residue_affected": { "residue_id": "N204", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] } ] } , { "glytoucan_ac": "G51695DM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G66016NA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51695DM", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G51699IR", "notes": [], "error": "No pathways for [G51699IR] could be generated at this time" }, { "glytoucan_ac": "G51699UE", "notes": [], "error": "No pathways for [G51699UE] could be generated at this time" }, { "glytoucan_ac": "G51710QD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80264ZA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51710QD", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G51715FH", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G44223QP]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G51715FH", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G51768ZH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G51768ZH] could be generated at this time" }, { "glytoucan_ac": "G51771NH", "notes": [], "error": "No pathways for [G51771NH] could be generated at this time" }, { "glytoucan_ac": "G51793MY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 } ], "links": [ { "target": "G51793MY", "source": "G45560HM", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51799AX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G51799AX] could be generated at this time" }, { "glytoucan_ac": "G51891DI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17473NR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 }, { "id": "G17473NR", "dp": 13 }, { "id": "G51891DI", "dp": 13 } ], "links": [ { "target": "G51891DI", "source": "G17473NR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17473NR", "source": "G10733HY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51896IF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G51908QJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G40670DJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51908QJ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G51921XC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72662IG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G80537QW", "dp": 14 }, { "id": "G72662IG", "dp": 15 }, { "id": "G51921XC", "dp": 15 } ], "links": [ { "target": "G51921XC", "source": "G72662IG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72662IG", "source": "G80537QW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G80537QW", "source": "G93582HM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51930XP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G01342FO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51930XP", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G51941IR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46425HN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G46425HN", "dp": 15 }, { "id": "G51941IR", "dp": 15 } ], "links": [ { "target": "G51941IR", "source": "G46425HN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46425HN", "source": "G45720CA", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G51956RJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G51971TR", "notes": [], "error": "No pathways for [G51971TR] could be generated at this time" }, { "glytoucan_ac": "G51987NK", "notes": [], "error": "No pathways for [G51987NK] could be generated at this time" }, { "glytoucan_ac": "G51995LA", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G79010UT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G51995LA", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G52034SY", "notes": [], "error": "No pathways for [G52034SY] could be generated at this time" }, { "glytoucan_ac": "G52056FF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G52056FF] could be generated at this time" }, { "glytoucan_ac": "G52070UO", "notes": [], "error": "No pathways for [G52070UO] could be generated at this time" }, { "glytoucan_ac": "G52080EW", "notes": [], "error": "No pathways for [G52080EW] could be generated at this time" }, { "glytoucan_ac": "G52080WL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G52080WL", "source": "G66937TJ", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52101PX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 }, { "id": "G95404EQ", "dp": 17 } ], "links": [ { "target": "G52101PX", "source": "G95404EQ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52112MC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G55396DW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G55396DW", "dp": 12 }, { "id": "G52112MC", "dp": 12 } ], "links": [ { "target": "G52112MC", "source": "G55396DW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G55396DW", "source": "G25520XG", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52153CS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G48802KI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G48802KI", "dp": 9 }, { "id": "G52153CS", "dp": 9 } ], "links": [ { "target": "G52153CS", "source": "G48802KI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G48802KI", "source": "G43677TG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52166GV", "notes": [], "error": "No pathways for [G52166GV] could be generated at this time" }, { "glytoucan_ac": "G52187WF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G02290KA", "dp": 10 } ], "links": [ { "target": "G52187WF", "source": "G02290KA", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G02290KA", "source": "G20030CU", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52216BO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24155DW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G52216BO", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G52224MB", "notes": [], "error": "No pathways for [G52224MB] could be generated at this time" }, { "glytoucan_ac": "G52225DV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G29797YX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 }, { "id": "G89181JW", "dp": 11 }, { "id": "G29797YX", "dp": 12 }, { "id": "G52225DV", "dp": 12 } ], "links": [ { "target": "G52225DV", "source": "G29797YX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29797YX", "source": "G89181JW", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G89181JW", "source": "G03445UI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52266YB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04989WY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G52266YB", "dp": 13 } ], "links": [ { "target": "G52266YB", "source": "G04989WY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52286UI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G15998WM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 }, { "id": "G15998WM", "dp": 17 }, { "id": "G52286UI", "dp": 17 } ], "links": [ { "target": "G52286UI", "source": "G15998WM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G15998WM", "source": "G79950YS", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52302PL", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G52302PL] could be generated at this time" }, { "glytoucan_ac": "G52333AW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 } ], "links": [ { "target": "G52333AW", "source": "G29492IF", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52333TF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G44504SC", "dp": 10 } ], "links": [ { "target": "G52333TF", "source": "G44504SC", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G44504SC", "source": "G20030CU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52336LJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 } ], "links": [ { "target": "G52336LJ", "source": "G30302VM", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52345FK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G52358FD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G67045LB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G52358FD", "dp": 8 } ], "links": [ { "target": "G52358FD", "source": "G67045LB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52383QH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G52428MJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 } ], "links": [ { "target": "G52428MJ", "source": "G42672MA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52441NC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04764ON]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G04764ON", "dp": 12 }, { "id": "G52441NC", "dp": 12 } ], "links": [ { "target": "G52441NC", "source": "G04764ON", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04764ON", "source": "G30302VM", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52461YB", "notes": [], "error": "No pathways for [G52461YB] could be generated at this time" }, { "glytoucan_ac": "G52483OL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G52483OL] could be generated at this time" }, { "glytoucan_ac": "G52498MU", "notes": [], "error": "No pathways for [G52498MU] could be generated at this time" }, { "glytoucan_ac": "G52633YA", "notes": [], "error": "No pathways for [G52633YA] could be generated at this time" }, { "glytoucan_ac": "G52645LW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 } ], "links": [ { "target": "G52645LW", "source": "G79578JB", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52663AD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52676LZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G32659RY", "dp": 12 } ], "links": [ { "target": "G52676LZ", "source": "G32659RY", "residue_affected": { "residue_id": "N108", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G32659RY", "source": "G59877NF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52677OK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G52724WY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G05260RH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 }, { "id": "G05260RH", "dp": 11 }, { "id": "G52724WY", "dp": 11 } ], "links": [ { "target": "G52724WY", "source": "G05260RH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G05260RH", "source": "G56591LC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52770HR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G52770HR", "source": "G36191CD", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52773YO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G52783KP", "notes": [], "error": "No pathways for [G52783KP] could be generated at this time" }, { "glytoucan_ac": "G52790YS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G68892PJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G52790YS", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G52793JJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G94838KN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G52793JJ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G52880ZN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 } ], "links": [ { "target": "G52880ZN", "source": "G82252QI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52882GL", "notes": [], "error": "No pathways for [G52882GL] could be generated at this time" }, { "glytoucan_ac": "G52886RR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G78503JC", "dp": 12 } ], "links": [ { "target": "G52886RR", "source": "G78503JC", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52892OT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G52928OQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49933AX]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G52928OQ", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G52934AK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 } ], "links": [ { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52956BX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G52956BX", "source": "G12398HZ", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G52971DE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14047PA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G14047PA", "dp": 11 }, { "id": "G52971DE", "dp": 11 } ], "links": [ { "target": "G52971DE", "source": "G14047PA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14047PA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53000RQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 } ], "links": [ { "target": "G53000RQ", "source": "G12740VA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53031JB", "notes": [], "error": "No pathways for [G53031JB] could be generated at this time" }, { "glytoucan_ac": "G53054ED", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 }, { "id": "G78741RD", "dp": 9 } ], "links": [ { "target": "G53054ED", "source": "G78741RD", "residue_affected": { "residue_id": "N422", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G78741RD", "source": "G64669AQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G53096UD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G53098FA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 } ], "links": [ { "target": "G53098FA", "source": "G95898GD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53168IY", "notes": [ "pathway start-point [G08520NM]" ], "error": "DP error for glycan [G53168IY] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G53170RJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G53170RJ", "source": "G11041DA", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53190JD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G64669AQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 }, { "id": "G53190JD", "dp": 8 } ], "links": [ { "target": "G53190JD", "source": "G64669AQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G53230JC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G79457WN", "dp": 11 } ], "links": [ { "target": "G53230JC", "source": "G79457WN", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79457WN", "source": "G00176HZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53234IR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G50489VC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G53234IR", "dp": 17 } ], "links": [ { "target": "G53234IR", "source": "G50489VC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53272SL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25406HP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53272SL", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G53288JQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G53288JQ] could be generated at this time" }, { "glytoucan_ac": "G53322JT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G53322JT", "source": "G00176HZ", "residue_affected": { "residue_id": "N502", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53342MA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30085SO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53342MA", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G53396PX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 } ], "links": [ { "target": "G53396PX", "source": "G82050MN", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53401FX", "notes": [], "error": "No pathways for [G53401FX] could be generated at this time" }, { "glytoucan_ac": "G53428EC", "notes": [], "error": "No pathways for [G53428EC] could be generated at this time" }, { "glytoucan_ac": "G53454TA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G53454TA] could be generated at this time" }, { "glytoucan_ac": "G53471VF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26274XD]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G26274XD", "dp": 11 }, { "id": "G53471VF", "dp": 11 } ], "links": [ { "target": "G53471VF", "source": "G26274XD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26274XD", "source": "G08187GM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53479GY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82312JY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G82312JY", "dp": 9 }, { "id": "G53479GY", "dp": 9 } ], "links": [ { "target": "G53479GY", "source": "G82312JY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82312JY", "source": "G80858MF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53485VW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53504BR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G53504BR] could be generated at this time" }, { "glytoucan_ac": "G53527OK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16956YO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53527OK", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G53567BY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G53582JE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58667NI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G53582JE", "dp": 9 } ], "links": [ { "target": "G53582JE", "source": "G58667NI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53605PF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 } ], "links": [ { "target": "G53605PF", "source": "G59741XZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53667CH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G53667CH] could be generated at this time" }, { "glytoucan_ac": "G53709ZS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G53723XK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G36519NW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G36519NW", "dp": 13 }, { "id": "G53723XK", "dp": 13 } ], "links": [ { "target": "G53723XK", "source": "G36519NW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36519NW", "source": "G01669LU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53728DU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G53728DU", "source": "G91365ZQ", "residue_affected": { "residue_id": "N276", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53752QB", "notes": [], "error": "No pathways for [G53752QB] could be generated at this time" }, { "glytoucan_ac": "G53752TA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 } ], "links": [ { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53795OV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10540LB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53795OV", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G53800MQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93698KA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53800MQ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G53809CJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79556AB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G79556AB", "dp": 12 }, { "id": "G53809CJ", "dp": 12 } ], "links": [ { "target": "G53809CJ", "source": "G79556AB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79556AB", "source": "G82252QI", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53812BX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 } ], "links": [ { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53817FJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G74120DW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53817FJ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G53854XZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G53854XZ] could be generated at this time" }, { "glytoucan_ac": "G53858MF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G33742YO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G33742YO", "dp": 9 }, { "id": "G53858MF", "dp": 9 } ], "links": [ { "target": "G53858MF", "source": "G33742YO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33742YO", "source": "G29011JC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53889SN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G52880ZN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G52880ZN", "dp": 12 }, { "id": "G53889SN", "dp": 12 } ], "links": [ { "target": "G53889SN", "source": "G52880ZN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52880ZN", "source": "G82252QI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53899GT", "notes": [], "error": "No pathways for [G53899GT] could be generated at this time" }, { "glytoucan_ac": "G53923UR", "notes": [], "error": "No pathways for [G53923UR] could be generated at this time" }, { "glytoucan_ac": "G53931MC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G51490BW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G53931MC", "dp": 8 } ], "links": [ { "target": "G53931MC", "source": "G51490BW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53933HU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 } ], "links": [ { "target": "G53933HU", "source": "G59741XZ", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53944MR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07337US]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G13156PQ", "dp": 12 }, { "id": "G07337US", "dp": 13 }, { "id": "G53944MR", "dp": 13 } ], "links": [ { "target": "G53944MR", "source": "G07337US", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07337US", "source": "G13156PQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G13156PQ", "source": "G53752TA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53956RO", "notes": [], "error": "No pathways for [G53956RO] could be generated at this time" }, { "glytoucan_ac": "G53962WT", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G53962WT] could be generated at this time" }, { "glytoucan_ac": "G53985AY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 } ], "links": [ { "target": "G53985AY", "source": "G78890OB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53989JC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25140TA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 }, { "id": "G53989JC", "dp": 11 } ], "links": [ { "target": "G53989JC", "source": "G25140TA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G53993HS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G41797PU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53993HS", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G53996MC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23419AQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G53996MC", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G54018RP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G54018RP] could be generated at this time" }, { "glytoucan_ac": "G54042WO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G59029AQ", "dp": 10 } ], "links": [ { "target": "G54042WO", "source": "G59029AQ", "residue_affected": { "residue_id": "N70", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G59029AQ", "source": "G04791QM", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54067ZR", "notes": [], "error": "No pathways for [G54067ZR] could be generated at this time" }, { "glytoucan_ac": "G54073XZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G95919TI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 }, { "id": "G95919TI", "dp": 14 }, { "id": "G54073XZ", "dp": 14 } ], "links": [ { "target": "G54073XZ", "source": "G95919TI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95919TI", "source": "G30651IU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54149OE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G11929SN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G11929SN", "dp": 14 }, { "id": "G54149OE", "dp": 14 } ], "links": [ { "target": "G54149OE", "source": "G11929SN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11929SN", "source": "G80294GH", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54151YB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47606XQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G26320VO", "dp": 10 }, { "id": "G47606XQ", "dp": 11 }, { "id": "G54151YB", "dp": 11 } ], "links": [ { "target": "G54151YB", "source": "G47606XQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47606XQ", "source": "G26320VO", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26320VO", "source": "G58667NI", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54158IT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90542MP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G54158IT", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G54177WI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G15727JK", "dp": 8 } ], "links": [ { "target": "G54177WI", "source": "G15727JK", "residue_affected": { "residue_id": "N400", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G15727JK", "source": "G69411IG", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54183MZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G05808PZ]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G03275SD", "dp": 10 }, { "id": "G05808PZ", "dp": 11 }, { "id": "G54183MZ", "dp": 11 } ], "links": [ { "target": "G54183MZ", "source": "G05808PZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G05808PZ", "source": "G03275SD", "residue_affected": { "residue_id": "N476", "pubchem_name": "phosphate", "anomer": "n", "absolute": "n", "form_name": "phosphate", "full_name": "-n-phosphate" }, "effect": "Adds -n-phosphate", "enzymes": [] }, { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54195NF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G34175ZP", "dp": 10 } ], "links": [ { "target": "G54195NF", "source": "G34175ZP", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G34175ZP", "source": "G01265XZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54255OI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77562VR]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G54255OI", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G54258NG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G56749GV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 }, { "id": "G54258NG", "dp": 12 } ], "links": [ { "target": "G54258NG", "source": "G56749GV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54260SD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G54260SD] could be generated at this time" }, { "glytoucan_ac": "G54269AZ", "notes": [], "error": "No pathways for [G54269AZ] could be generated at this time" }, { "glytoucan_ac": "G54273KX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G07410AW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 }, { "id": "G07410AW", "dp": 14 }, { "id": "G54273KX", "dp": 14 } ], "links": [ { "target": "G54273KX", "source": "G07410AW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07410AW", "source": "G37597FW", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54300AX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G54300AX] could be generated at this time" }, { "glytoucan_ac": "G54338PJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G16150CJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 }, { "id": "G54338PJ", "dp": 14 } ], "links": [ { "target": "G54338PJ", "source": "G16150CJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54380FJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G68937TM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G54380FJ", "dp": 10 } ], "links": [ { "target": "G54380FJ", "source": "G68937TM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54411RI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39029JR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G39029JR", "dp": 10 }, { "id": "G54411RI", "dp": 10 } ], "links": [ { "target": "G54411RI", "source": "G39029JR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39029JR", "source": "G93500PH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54466RT", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G49933AX]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G54466RT", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G54499PQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78890OB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 }, { "id": "G54499PQ", "dp": 10 } ], "links": [ { "target": "G54499PQ", "source": "G78890OB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54505OS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 } ], "links": [ { "target": "G54505OS", "source": "G65597BI", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54513OG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46767VX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G54513OG", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G54533TM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G36176RV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G36176RV", "dp": 12 }, { "id": "G54533TM", "dp": 12 } ], "links": [ { "target": "G54533TM", "source": "G36176RV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36176RV", "source": "G30302VM", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54584ER", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G54584ER", "source": "G18938DW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54590FS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G54590FS] could be generated at this time" }, { "glytoucan_ac": "G54599TH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65449BO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G36519NW", "dp": 13 }, { "id": "G65449BO", "dp": 14 }, { "id": "G54599TH", "dp": 14 } ], "links": [ { "target": "G54599TH", "source": "G65449BO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65449BO", "source": "G36519NW", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G36519NW", "source": "G01669LU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54599TV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G83588YY", "dp": 15 } ], "links": [ { "target": "G54599TV", "source": "G83588YY", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G83588YY", "source": "G11953VE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54611ZT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54626GN", "notes": [], "error": "No pathways for [G54626GN] could be generated at this time" }, { "glytoucan_ac": "G54683UA", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G01069AK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G01069AK", "dp": 11 }, { "id": "G54683UA", "dp": 11 } ], "links": [ { "target": "G54683UA", "source": "G01069AK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01069AK", "source": "G91365ZQ", "residue_affected": { "residue_id": "N216", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54715UD", "notes": [], "error": "No pathways for [G54715UD] could be generated at this time" }, { "glytoucan_ac": "G54764AV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91337ZP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G91337ZP", "dp": 10 }, { "id": "G54764AV", "dp": 10 } ], "links": [ { "target": "G54764AV", "source": "G91337ZP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91337ZP", "source": "G58667NI", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54775DO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G13267ZY", "dp": 10 }, { "id": "G86681BW", "dp": 11 } ], "links": [ { "target": "G54775DO", "source": "G86681BW", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G86681BW", "source": "G13267ZY", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G13267ZY", "source": "G46638GC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54884LT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G29434RB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G54884LT", "dp": 9 } ], "links": [ { "target": "G54884LT", "source": "G29434RB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G54950JZ", "notes": [], "error": "No pathways for [G54950JZ] could be generated at this time" }, { "glytoucan_ac": "G54953LX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G54953LX] could be generated at this time" }, { "glytoucan_ac": "G54956ME", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G54956ME] could be generated at this time" }, { "glytoucan_ac": "G54961LP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97686QU]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G54961LP", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G54963QY", "notes": [], "error": "No pathways for [G54963QY] could be generated at this time" }, { "glytoucan_ac": "G54977LV", "notes": [], "error": "No pathways for [G54977LV] could be generated at this time" }, { "glytoucan_ac": "G54986EB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G54986EB] could be generated at this time" }, { "glytoucan_ac": "G55015QS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 } ], "links": [ { "target": "G55015QS", "source": "G72718TT", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55041IW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25835MT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G25835MT", "dp": 10 }, { "id": "G55041IW", "dp": 10 } ], "links": [ { "target": "G55041IW", "source": "G25835MT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55065WV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71857KQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G71857KQ", "dp": 10 }, { "id": "G55065WV", "dp": 10 } ], "links": [ { "target": "G55065WV", "source": "G71857KQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71857KQ", "source": "G29434RB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55070AA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G12699VT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G12699VT", "dp": 11 }, { "id": "G55070AA", "dp": 11 } ], "links": [ { "target": "G55070AA", "source": "G12699VT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12699VT", "source": "G78059CC", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55086SI", "notes": [], "error": "No pathways for [G55086SI] could be generated at this time" }, { "glytoucan_ac": "G55099PN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G44504SC", "dp": 10 } ], "links": [ { "target": "G55099PN", "source": "G44504SC", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G44504SC", "source": "G20030CU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55143WF", "notes": [], "error": "No pathways for [G55143WF] could be generated at this time" }, { "glytoucan_ac": "G55146FI", "notes": [], "error": "No pathways for [G55146FI] could be generated at this time" }, { "glytoucan_ac": "G55157XP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G55184GH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G18219CJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G55184GH", "dp": 11 } ], "links": [ { "target": "G55184GH", "source": "G18219CJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55192VG", "notes": [], "error": "No pathways for [G55192VG] could be generated at this time" }, { "glytoucan_ac": "G55220VL", "notes": [], "error": "No pathways for [G55220VL] could be generated at this time" }, { "glytoucan_ac": "G55258MY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G26949IX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 }, { "id": "G55258MY", "dp": 11 } ], "links": [ { "target": "G55258MY", "source": "G26949IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55302WQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G20030CU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G55302WQ", "dp": 9 } ], "links": [ { "target": "G55302WQ", "source": "G20030CU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55314RK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G55314RK] could be generated at this time" }, { "glytoucan_ac": "G55327VV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G41331JX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 }, { "id": "G55327VV", "dp": 12 } ], "links": [ { "target": "G55327VV", "source": "G41331JX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55360MM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G55360NR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G59300GC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G59300GC", "dp": 14 }, { "id": "G55360NR", "dp": 14 } ], "links": [ { "target": "G55360NR", "source": "G59300GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59300GC", "source": "G73492AT", "residue_affected": { "residue_id": "N78", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55396DW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G55396DW", "source": "G25520XG", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55479DB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G11929SN", "dp": 14 } ], "links": [ { "target": "G55479DB", "source": "G11929SN", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G11929SN", "source": "G80294GH", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55481KF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39439UR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G39439UR", "dp": 9 }, { "id": "G55481KF", "dp": 9 } ], "links": [ { "target": "G55481KF", "source": "G39439UR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39439UR", "source": "G10209QU", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55600PH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82811EP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82811EP", "dp": 13 }, { "id": "G55600PH", "dp": 13 } ], "links": [ { "target": "G55600PH", "source": "G82811EP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82811EP", "source": "G84376FR", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55645TD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G55645TD] could be generated at this time" }, { "glytoucan_ac": "G55653LB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G80294GH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G55653LB", "dp": 13 } ], "links": [ { "target": "G55653LB", "source": "G80294GH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55743SL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G74090KZ", "dp": 7 }, { "id": "G50222RE", "dp": 8 } ], "links": [ { "target": "G55743SL", "source": "G50222RE", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G50222RE", "source": "G74090KZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G74090KZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55781KV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G57166CI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G55781KV", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G55786MG", "notes": [], "error": "No pathways for [G55786MG] could be generated at this time" }, { "glytoucan_ac": "G55818EE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G17689DH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G17689DH", "dp": 12 }, { "id": "G55818EE", "dp": 12 } ], "links": [ { "target": "G55818EE", "source": "G17689DH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55828KH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G32201IL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G55828KH", "dp": 10 } ], "links": [ { "target": "G55828KH", "source": "G32201IL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55832RR", "notes": [], "error": "No pathways for [G55832RR] could be generated at this time" }, { "glytoucan_ac": "G55861FV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G18768EK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G18768EK", "dp": 11 }, { "id": "G55861FV", "dp": 11 } ], "links": [ { "target": "G55861FV", "source": "G18768EK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18768EK", "source": "G78803YD", "residue_affected": { "residue_id": "N78", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55867TY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25471TG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G55867TY", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G55879PV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26320VO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G26320VO", "dp": 10 }, { "id": "G55879PV", "dp": 10 } ], "links": [ { "target": "G55879PV", "source": "G26320VO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26320VO", "source": "G58667NI", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55953GF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45048TZ]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G55953GF", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G55974RB", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 } ], "links": [ { "target": "G55974RB", "source": "G08187GM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55979JS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G66665YI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G66665YI", "dp": 14 }, { "id": "G55979JS", "dp": 14 } ], "links": [ { "target": "G55979JS", "source": "G66665YI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66665YI", "source": "G66282NU", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G55992IN", "notes": [], "error": "No pathways for [G55992IN] could be generated at this time" }, { "glytoucan_ac": "G56014GC", "notes": [], "error": "No pathways for [G56014GC] could be generated at this time" }, { "glytoucan_ac": "G56017FW", "notes": [], "error": "No pathways for [G56017FW] could be generated at this time" }, { "glytoucan_ac": "G56038AR", "notes": [], "error": "No pathways for [G56038AR] could be generated at this time" }, { "glytoucan_ac": "G56095ZZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29130SY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G56095ZZ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G56147VV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 } ], "links": [ { "target": "G56147VV", "source": "G17168RO", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56163DR", "notes": [], "error": "No pathways for [G56163DR] could be generated at this time" }, { "glytoucan_ac": "G56175ED", "notes": [], "error": "No pathways for [G56175ED] could be generated at this time" }, { "glytoucan_ac": "G56175MM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74807KC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G09150LP", "dp": 12 }, { "id": "G78097CL", "dp": 13 }, { "id": "G74807KC", "dp": 14 }, { "id": "G56175MM", "dp": 14 } ], "links": [ { "target": "G56175MM", "source": "G74807KC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74807KC", "source": "G78097CL", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78097CL", "source": "G09150LP", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G09150LP", "source": "G88948CY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56202TA", "notes": [], "error": "No pathways for [G56202TA] could be generated at this time" }, { "glytoucan_ac": "G56265BA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58473KL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G56265BA", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G56269EA", "notes": [], "error": "No pathways for [G56269EA] could be generated at this time" }, { "glytoucan_ac": "G56271ML", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95617FJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G95617FJ", "dp": 12 }, { "id": "G56271ML", "dp": 12 } ], "links": [ { "target": "G56271ML", "source": "G95617FJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95617FJ", "source": "G25520XG", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56271TF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 } ], "links": [ { "target": "G56271TF", "source": "G59741XZ", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56318NV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G75237SS", "dp": 16 } ], "links": [ { "target": "G56318NV", "source": "G75237SS", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56328RB", "notes": [], "error": "No pathways for [G56328RB] could be generated at this time" }, { "glytoucan_ac": "G56329KE", "notes": [], "error": "No pathways for [G56329KE] could be generated at this time" }, { "glytoucan_ac": "G56339QG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G56339QG", "source": "G29857RC", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56340GX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 } ], "links": [ { "target": "G56340GX", "source": "G27919IH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56354PO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G56354PO] could be generated at this time" }, { "glytoucan_ac": "G56376TA", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G17213JF", "dp": 11 } ], "links": [ { "target": "G56376TA", "source": "G17213JF", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56381GU", "notes": [], "error": "No pathways for [G56381GU] could be generated at this time" }, { "glytoucan_ac": "G56408DR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G24875YE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G56408DR", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G56485SI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G56485SI] could be generated at this time" }, { "glytoucan_ac": "G56492IM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G56499YQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 } ], "links": [ { "target": "G56499YQ", "source": "G57955DP", "residue_affected": { "residue_id": "N228", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56512DX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G01856RL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 }, { "id": "G56512DX", "dp": 10 } ], "links": [ { "target": "G56512DX", "source": "G01856RL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56516KW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G56516KW] could be generated at this time" }, { "glytoucan_ac": "G56546LQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G56549DH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 } ], "links": [ { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56577TY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G56591LC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56621NM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 }, { "id": "G08205LJ", "dp": 13 } ], "links": [ { "target": "G56621NM", "source": "G08205LJ", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G08205LJ", "source": "G48658PB", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56653RI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10219AA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G56653RI", "dp": 8 } ], "links": [ { "target": "G56653RI", "source": "G10219AA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56655CC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G63889NK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G56655CC", "dp": 14 } ], "links": [ { "target": "G56655CC", "source": "G63889NK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56657CK", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G77252PU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 }, { "id": "G56657CK", "dp": 11 } ], "links": [ { "target": "G56657CK", "source": "G77252PU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56691CA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G56691CA] could be generated at this time" }, { "glytoucan_ac": "G56703XH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50135PA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G56703XH", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G56720TK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G56720TK] could be generated at this time" }, { "glytoucan_ac": "G56737NO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10209QU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G56737NO", "dp": 8 } ], "links": [ { "target": "G56737NO", "source": "G10209QU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56748EO", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 } ], "links": [ { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56749GV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56770AH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10228OD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 }, { "id": "G56770AH", "dp": 14 } ], "links": [ { "target": "G56770AH", "source": "G10228OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56791SN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95898GD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 }, { "id": "G56791SN", "dp": 13 } ], "links": [ { "target": "G56791SN", "source": "G95898GD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56809FB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G66595IQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G56809FB", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G56811RE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G56830SM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G57943ZV", "dp": 11 } ], "links": [ { "target": "G56830SM", "source": "G57943ZV", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G57943ZV", "source": "G52934AK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56851CO", "notes": [], "error": "No pathways for [G56851CO] could be generated at this time" }, { "glytoucan_ac": "G56852BX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72221XM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G45187EI", "dp": 11 }, { "id": "G72221XM", "dp": 12 }, { "id": "G56852BX", "dp": 12 } ], "links": [ { "target": "G56852BX", "source": "G72221XM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72221XM", "source": "G45187EI", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G45187EI", "source": "G08577ZR", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56867YK", "notes": [], "error": "No pathways for [G56867YK] could be generated at this time" }, { "glytoucan_ac": "G56869RQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96091LW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G07228BR", "dp": 10 }, { "id": "G96091LW", "dp": 11 }, { "id": "G56869RQ", "dp": 11 } ], "links": [ { "target": "G56869RQ", "source": "G96091LW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96091LW", "source": "G07228BR", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07228BR", "source": "G93500PH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56891ZN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G54590FS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G56891ZN", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G56893CG", "notes": [], "error": "No pathways for [G56893CG] could be generated at this time" }, { "glytoucan_ac": "G56963QZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56318NV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G75237SS", "dp": 16 }, { "id": "G56318NV", "dp": 17 }, { "id": "G56963QZ", "dp": 17 } ], "links": [ { "target": "G56963QZ", "source": "G56318NV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56318NV", "source": "G75237SS", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G56977BH", "notes": [], "error": "No pathways for [G56977BH] could be generated at this time" }, { "glytoucan_ac": "G56988MG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74497TS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G56988MG", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G57040DY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G57051OG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10295MW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G57051OG", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G57075KG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95695ZV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G57075KG", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G57075OH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41981MA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G41981MA", "dp": 15 }, { "id": "G57075OH", "dp": 15 } ], "links": [ { "target": "G57075OH", "source": "G41981MA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41981MA", "source": "G38022PE", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57083FO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G57084IU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G57092OJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G57092OJ", "source": "G58667NI", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57117TO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G57117TO", "source": "G69411IG", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57158CS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G72974NP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 }, { "id": "G01354KL", "dp": 14 }, { "id": "G72974NP", "dp": 15 }, { "id": "G57158CS", "dp": 15 } ], "links": [ { "target": "G57158CS", "source": "G72974NP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72974NP", "source": "G01354KL", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01354KL", "source": "G41611UP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57166CI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G57166CI] could be generated at this time" }, { "glytoucan_ac": "G57208CK", "notes": [], "error": "No pathways for [G57208CK] could be generated at this time" }, { "glytoucan_ac": "G57220BY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G78648QN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G57220BY", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G57260LH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 } ], "links": [ { "target": "G57260LH", "source": "G89877QI", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57262WV", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G06209KS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G06209KS", "dp": 8 }, { "id": "G57262WV", "dp": 8 } ], "links": [ { "target": "G57262WV", "source": "G06209KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06209KS", "source": "G69411IG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57267KB", "notes": [], "error": "No pathways for [G57267KB] could be generated at this time" }, { "glytoucan_ac": "G57338PU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G90130AG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G57338PU", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G57345HS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G57345HS] could be generated at this time" }, { "glytoucan_ac": "G57449OF", "notes": [], "error": "No pathways for [G57449OF] could be generated at this time" }, { "glytoucan_ac": "G57466QX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 } ], "links": [ { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57484FV", "notes": [], "error": "No pathways for [G57484FV] could be generated at this time" }, { "glytoucan_ac": "G57504TA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G28723UT", "dp": 11 } ], "links": [ { "target": "G57504TA", "source": "G28723UT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28723UT", "source": "G87073UP", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57511DS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G85650LS", "dp": 11 } ], "links": [ { "target": "G57511DS", "source": "G85650LS", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85650LS", "source": "G28826SH", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57522MT", "notes": [], "error": "No pathways for [G57522MT] could be generated at this time" }, { "glytoucan_ac": "G57565TQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G57565TQ] could be generated at this time" }, { "glytoucan_ac": "G57580SM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G43664YB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G43664YB", "dp": 9 }, { "id": "G57580SM", "dp": 9 } ], "links": [ { "target": "G57580SM", "source": "G43664YB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43664YB", "source": "G24420RT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57595UE", "notes": [], "error": "No pathways for [G57595UE] could be generated at this time" }, { "glytoucan_ac": "G57601AP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G73817GH", "dp": 10 } ], "links": [ { "target": "G57601AP", "source": "G73817GH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57601KU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 } ], "links": [ { "target": "G57601KU", "source": "G81663ZI", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57626SM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57671LP]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G57626SM", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G57671LP", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G57671LP] could be generated at this time" }, { "glytoucan_ac": "G57675TR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G57675TR] could be generated at this time" }, { "glytoucan_ac": "G57707WO", "notes": [], "error": "No pathways for [G57707WO] could be generated at this time" }, { "glytoucan_ac": "G57741SS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G57762GE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G92359VA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G57762GE", "dp": 13 } ], "links": [ { "target": "G57762GE", "source": "G92359VA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57774MT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74074HU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G57774MT", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G57835AK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G57835AK] could be generated at this time" }, { "glytoucan_ac": "G57843KJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G61088TM", "dp": 12 } ], "links": [ { "target": "G57843KJ", "source": "G61088TM", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61088TM", "source": "G90870DG", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57863LA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G57863LA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57881VN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24327OK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G57881VN", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G57930PW", "notes": [], "error": "No pathways for [G57930PW] could be generated at this time" }, { "glytoucan_ac": "G57937LQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G57941UT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G61553DD", "dp": 9 } ], "links": [ { "target": "G57941UT", "source": "G61553DD", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61553DD", "source": "G29011JC", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57943ZV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G57943ZV", "source": "G52934AK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57955DP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 } ], "links": [ { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57956SV", "notes": [], "error": "No pathways for [G57956SV] could be generated at this time" }, { "glytoucan_ac": "G57970NA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 } ], "links": [ { "target": "G57970NA", "source": "G49515VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G57997IN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G11509RN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G11509RN", "dp": 12 }, { "id": "G57997IN", "dp": 12 } ], "links": [ { "target": "G57997IN", "source": "G11509RN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11509RN", "source": "G30302VM", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58004KD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16873YG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G58004KD", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G58029XR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G85260RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 }, { "id": "G85260RY", "dp": 16 }, { "id": "G58029XR", "dp": 16 } ], "links": [ { "target": "G58029XR", "source": "G85260RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85260RY", "source": "G57955DP", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58111YY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82033VN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G82033VN", "dp": 14 }, { "id": "G58111YY", "dp": 14 } ], "links": [ { "target": "G58111YY", "source": "G82033VN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82033VN", "source": "G20926BB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58143RL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07802IC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 }, { "id": "G07802IC", "dp": 13 }, { "id": "G58143RL", "dp": 13 } ], "links": [ { "target": "G58143RL", "source": "G07802IC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07802IC", "source": "G56749GV", "residue_affected": { "residue_id": "N483", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58183RP", "notes": [], "error": "No pathways for [G58183RP] could be generated at this time" }, { "glytoucan_ac": "G58198HJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82487CR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G82487CR", "dp": 15 }, { "id": "G58198HJ", "dp": 15 } ], "links": [ { "target": "G58198HJ", "source": "G82487CR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82487CR", "source": "G08194HH", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58214IQ", "notes": [], "error": "No pathways for [G58214IQ] could be generated at this time" }, { "glytoucan_ac": "G58216EF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82050MN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 }, { "id": "G58216EF", "dp": 13 } ], "links": [ { "target": "G58216EF", "source": "G82050MN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58217PP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G91413ZX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G91413ZX", "dp": 15 }, { "id": "G58217PP", "dp": 15 } ], "links": [ { "target": "G58217PP", "source": "G91413ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58233BW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88582ZD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G58233BW", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G58236FD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07995VK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 }, { "id": "G58236FD", "dp": 10 } ], "links": [ { "target": "G58236FD", "source": "G07995VK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58244GN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G33202XC", "dp": 13 } ], "links": [ { "target": "G58244GN", "source": "G33202XC", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G33202XC", "source": "G75185NU", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58251YC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G58251YC] could be generated at this time" }, { "glytoucan_ac": "G58281SK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 } ], "links": [ { "target": "G58281SK", "source": "G59471TH", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58328JK", "notes": [], "error": "No pathways for [G58328JK] could be generated at this time" }, { "glytoucan_ac": "G58331OS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31637BB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G58331OS", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G58350LJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G29857RC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G58350LJ", "dp": 11 } ], "links": [ { "target": "G58350LJ", "source": "G29857RC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58381OV", "notes": [], "error": "No pathways for [G58381OV] could be generated at this time" }, { "glytoucan_ac": "G58403SV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 } ], "links": [ { "target": "G58403SV", "source": "G99270AV", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58422UX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G91208VE", "dp": 9 } ], "links": [ { "target": "G58422UX", "source": "G91208VE", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58473KL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G58473KL] could be generated at this time" }, { "glytoucan_ac": "G58516UP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G14512NS", "dp": 9 } ], "links": [ { "target": "G58516UP", "source": "G14512NS", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G14512NS", "source": "G24420RT", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58517TJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45187EI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G45187EI", "dp": 11 }, { "id": "G58517TJ", "dp": 11 } ], "links": [ { "target": "G58517TJ", "source": "G45187EI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45187EI", "source": "G08577ZR", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58547FH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G58547FH] could be generated at this time" }, { "glytoucan_ac": "G58561KE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G91023GB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G58561KE", "dp": 12 } ], "links": [ { "target": "G58561KE", "source": "G91023GB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58571IP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10228OD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 }, { "id": "G58571IP", "dp": 14 } ], "links": [ { "target": "G58571IP", "source": "G10228OD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58585VA", "notes": [ "reducing end mismatch [o-D-GlcNAc]", "homologous pathway end-point [G62504BU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G58585VA", "dp": 10 } ], "links": [ { "target": "G58585VA", "source": "G62504BU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58667NI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58746AB", "notes": [], "error": "No pathways for [G58746AB] could be generated at this time" }, { "glytoucan_ac": "G58768FH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G58768FH] could be generated at this time" }, { "glytoucan_ac": "G58780EA", "notes": [], "error": "No pathways for [G58780EA] could be generated at this time" }, { "glytoucan_ac": "G58807XI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G29026MS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G29026MS", "dp": 12 }, { "id": "G58807XI", "dp": 12 } ], "links": [ { "target": "G58807XI", "source": "G29026MS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29026MS", "source": "G59877NF", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58808TX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95658PH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G58808TX", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G58809AD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G84852GW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G84852GW", "dp": 9 }, { "id": "G58809AD", "dp": 9 } ], "links": [ { "target": "G58809AD", "source": "G84852GW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84852GW", "source": "G12398HZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58824LL", "notes": [], "error": "No pathways for [G58824LL] could be generated at this time" }, { "glytoucan_ac": "G58827HR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G58827HR] could be generated at this time" }, { "glytoucan_ac": "G58839SI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G58839SI] could be generated at this time" }, { "glytoucan_ac": "G58918TF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30880RA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G58918TF", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G58931VV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51098AA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G58931VV", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G58955OJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00951UF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G79198BK", "dp": 9 }, { "id": "G00951UF", "dp": 10 }, { "id": "G58955OJ", "dp": 10 } ], "links": [ { "target": "G58955OJ", "source": "G00951UF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00951UF", "source": "G79198BK", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G79198BK", "source": "G10219AA", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G58969RU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G58969RU] could be generated at this time" }, { "glytoucan_ac": "G58992VJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58969RU]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G58992VJ", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G58995TS", "notes": [], "error": "No pathways for [G58995TS] could be generated at this time" }, { "glytoucan_ac": "G59003TR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93582HM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G59003TR", "dp": 13 } ], "links": [ { "target": "G59003TR", "source": "G93582HM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59024DC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G45187EI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G45187EI", "dp": 11 }, { "id": "G59024DC", "dp": 11 } ], "links": [ { "target": "G59024DC", "source": "G45187EI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45187EI", "source": "G08577ZR", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59029AQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 } ], "links": [ { "target": "G59029AQ", "source": "G04791QM", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59041MP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97674NY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G97674NY", "dp": 15 }, { "id": "G59041MP", "dp": 15 } ], "links": [ { "target": "G59041MP", "source": "G97674NY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G97674NY", "source": "G89877QI", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59081JJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G59128IS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 }, { "id": "G56147VV", "dp": 15 } ], "links": [ { "target": "G59128IS", "source": "G56147VV", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G56147VV", "source": "G17168RO", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59141EN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57863LA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G57863LA", "dp": 11 }, { "id": "G59141EN", "dp": 11 } ], "links": [ { "target": "G59141EN", "source": "G57863LA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57863LA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59149SL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00743WU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G00743WU", "dp": 11 }, { "id": "G59149SL", "dp": 11 } ], "links": [ { "target": "G59149SL", "source": "G00743WU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59159PE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G59159PE] could be generated at this time" }, { "glytoucan_ac": "G59231NT", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G59231NT] could be generated at this time" }, { "glytoucan_ac": "G59255VT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G70520DS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G90348RI", "dp": 12 }, { "id": "G70520DS", "dp": 13 }, { "id": "G59255VT", "dp": 13 } ], "links": [ { "target": "G59255VT", "source": "G70520DS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70520DS", "source": "G90348RI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G90348RI", "source": "G11041DA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59256VO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74675FC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 }, { "id": "G59256VO", "dp": 11 } ], "links": [ { "target": "G59256VO", "source": "G74675FC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59258LC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82050MN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 }, { "id": "G59258LC", "dp": 13 } ], "links": [ { "target": "G59258LC", "source": "G82050MN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59277TZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 } ], "links": [ { "target": "G59277TZ", "source": "G30159WR", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59300GC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 } ], "links": [ { "target": "G59300GC", "source": "G73492AT", "residue_affected": { "residue_id": "N78", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59311AO", "notes": [], "error": "No pathways for [G59311AO] could be generated at this time" }, { "glytoucan_ac": "G59345UT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16150CJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 }, { "id": "G59345UT", "dp": 14 } ], "links": [ { "target": "G59345UT", "source": "G16150CJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59361OW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 } ], "links": [ { "target": "G59361OW", "source": "G44946WH", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59406KS", "notes": [], "error": "No pathways for [G59406KS] could be generated at this time" }, { "glytoucan_ac": "G59451NL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G59451NL", "source": "G39213VZ", "residue_affected": { "residue_id": "N299", "pubchem_name": "Fuc", "anomer": "b", "absolute": "L", "form_name": "Fucp", "full_name": "β-L-Fucp" }, "effect": "Adds β-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59454IE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G48954CA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G48954CA", "dp": 9 }, { "id": "G59454IE", "dp": 9 } ], "links": [ { "target": "G59454IE", "source": "G48954CA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G48954CA", "source": "G12398HZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59456VR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G59458AW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G59471JC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53854XZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G59471JC", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G59471TH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59513YA", "notes": [], "error": "No pathways for [G59513YA] could be generated at this time" }, { "glytoucan_ac": "G59532XE", "notes": [], "error": "No pathways for [G59532XE] could be generated at this time" }, { "glytoucan_ac": "G59575FI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G03275SD", "dp": 10 }, { "id": "G66129DI", "dp": 11 } ], "links": [ { "target": "G59575FI", "source": "G66129DI", "residue_affected": { "residue_id": "N476", "pubchem_name": "phosphate", "anomer": "n", "absolute": "n", "form_name": "phosphate", "full_name": "-n-phosphate" }, "effect": "Adds -n-phosphate", "enzymes": [] }, { "target": "G66129DI", "source": "G03275SD", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59579TL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G86753CK", "dp": 17 } ], "links": [ { "target": "G59579TL", "source": "G86753CK", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86753CK", "source": "G02311IE", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59594CP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G66282NU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G59594CP", "dp": 13 } ], "links": [ { "target": "G59594CP", "source": "G66282NU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59619LB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G14393TF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G59619LB", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G59621EZ", "notes": [], "error": "No pathways for [G59621EZ] could be generated at this time" }, { "glytoucan_ac": "G59636XZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G41087ZA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G59636XZ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G59655SA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 } ], "links": [ { "target": "G59655SA", "source": "G53752TA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59716UA", "notes": [], "error": "No pathways for [G59716UA] could be generated at this time" }, { "glytoucan_ac": "G59741XZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59742GY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G59742GY] could be generated at this time" }, { "glytoucan_ac": "G59742ZT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G59746QC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 } ], "links": [ { "target": "G59746QC", "source": "G00909PI", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59752BW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G59752BW] could be generated at this time" }, { "glytoucan_ac": "G59761EF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98453VS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G59761EF", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G59804RR", "notes": [], "error": "No pathways for [G59804RR] could be generated at this time" }, { "glytoucan_ac": "G59869XG", "notes": [], "error": "No pathways for [G59869XG] could be generated at this time" }, { "glytoucan_ac": "G59877NF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 } ], "links": [ { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59897WN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G59910CM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G86555OF]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G59910CM", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G59915YZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 } ], "links": [ { "target": "G59915YZ", "source": "G79609RF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59942FB", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G56748EO", "dp": 10 } ], "links": [ { "target": "G59942FB", "source": "G56748EO", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59984BF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G23626NI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G23626NI", "dp": 11 }, { "id": "G59984BF", "dp": 11 } ], "links": [ { "target": "G59984BF", "source": "G23626NI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23626NI", "source": "G85542KD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G59989VG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G59989VG] could be generated at this time" }, { "glytoucan_ac": "G60012HO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G96921ZU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G96921ZU", "dp": 12 }, { "id": "G60012HO", "dp": 12 } ], "links": [ { "target": "G60012HO", "source": "G96921ZU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96921ZU", "source": "G11041DA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60103QI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G54611ZT", "dp": 11 } ], "links": [ { "target": "G60103QI", "source": "G54611ZT", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60149QJ", "notes": [], "error": "No pathways for [G60149QJ] could be generated at this time" }, { "glytoucan_ac": "G60176QG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46661UU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G73817GH", "dp": 10 }, { "id": "G57601AP", "dp": 11 }, { "id": "G11615SW", "dp": 12 }, { "id": "G46661UU", "dp": 13 }, { "id": "G60176QG", "dp": 13 } ], "links": [ { "target": "G60176QG", "source": "G46661UU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46661UU", "source": "G11615SW", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G11615SW", "source": "G57601AP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G57601AP", "source": "G73817GH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60215UL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G47175EF", "dp": 11 } ], "links": [ { "target": "G60215UL", "source": "G47175EF", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60227QI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G60227QI] could be generated at this time" }, { "glytoucan_ac": "G60230HH", "notes": [], "error": "No pathways for [G60230HH] could be generated at this time" }, { "glytoucan_ac": "G60233QP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G47554EG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G60233QP", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G60269YM", "notes": [], "error": "No pathways for [G60269YM] could be generated at this time" }, { "glytoucan_ac": "G60274JN", "notes": [], "error": "No pathways for [G60274JN] could be generated at this time" }, { "glytoucan_ac": "G60284TY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G60320IS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G94045IP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G94045IP", "dp": 13 }, { "id": "G60320IS", "dp": 13 } ], "links": [ { "target": "G60320IS", "source": "G94045IP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94045IP", "source": "G91023GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60330MA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56147VV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 }, { "id": "G56147VV", "dp": 15 }, { "id": "G60330MA", "dp": 15 } ], "links": [ { "target": "G60330MA", "source": "G56147VV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56147VV", "source": "G17168RO", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60343KO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G60359JC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G62883YA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 }, { "id": "G62883YA", "dp": 11 }, { "id": "G60359JC", "dp": 11 } ], "links": [ { "target": "G60359JC", "source": "G62883YA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62883YA", "source": "G66866LE", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60370CP", "notes": [], "error": "No pathways for [G60370CP] could be generated at this time" }, { "glytoucan_ac": "G60383WH", "notes": [], "error": "No pathways for [G60383WH] could be generated at this time" }, { "glytoucan_ac": "G60413OP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G60415BS", "notes": [], "error": "No pathways for [G60415BS] could be generated at this time" }, { "glytoucan_ac": "G60419KX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G96963QG", "dp": 12 }, { "id": "G73759SD", "dp": 13 } ], "links": [ { "target": "G60419KX", "source": "G73759SD", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G73759SD", "source": "G96963QG", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60439QY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 }, { "id": "G37990ZT", "dp": 15 }, { "id": "G99891PR", "dp": 16 } ], "links": [ { "target": "G60439QY", "source": "G99891PR", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99891PR", "source": "G37990ZT", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60464IB", "notes": [], "error": "No pathways for [G60464IB] could be generated at this time" }, { "glytoucan_ac": "G60485RX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G36581MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G60485RX", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G60496TU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03296OS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G60496TU", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G60532CM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58768FH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G60532CM", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G60534NQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G52934AK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G60534NQ", "dp": 10 } ], "links": [ { "target": "G60534NQ", "source": "G52934AK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60564DP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60604SE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17339LD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G52770HR", "dp": 10 }, { "id": "G17339LD", "dp": 11 }, { "id": "G60604SE", "dp": 11 } ], "links": [ { "target": "G60604SE", "source": "G17339LD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17339LD", "source": "G52770HR", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G52770HR", "source": "G36191CD", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60605VB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 } ], "links": [ { "target": "G60605VB", "source": "G04791QM", "residue_affected": { "residue_id": "N422", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60610NA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G20018DL", "dp": 14 }, { "id": "G06968OS", "dp": 15 } ], "links": [ { "target": "G60610NA", "source": "G06968OS", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G06968OS", "source": "G20018DL", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G20018DL", "source": "G18938DW", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60646UB", "notes": [], "error": "No pathways for [G60646UB] could be generated at this time" }, { "glytoucan_ac": "G60653VD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85542KD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G60653VD", "dp": 10 } ], "links": [ { "target": "G60653VD", "source": "G85542KD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60660BN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 } ], "links": [ { "target": "G60660BN", "source": "G10228OD", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60667OL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G11535IB", "dp": 9 } ], "links": [ { "target": "G60667OL", "source": "G11535IB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11535IB", "source": "G59471TH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60692DB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10182XZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G60692DB", "dp": 7 } ], "links": [ { "target": "G60692DB", "source": "G10182XZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60705KN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79394LC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G97765TT", "dp": 12 }, { "id": "G79394LC", "dp": 13 }, { "id": "G60705KN", "dp": 13 } ], "links": [ { "target": "G60705KN", "source": "G79394LC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79394LC", "source": "G97765TT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G97765TT", "source": "G18219CJ", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60736DD", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G84467IZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 }, { "id": "G60736DD", "dp": 11 } ], "links": [ { "target": "G60736DD", "source": "G84467IZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60765GV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G04554UL", "dp": 11 } ], "links": [ { "target": "G60765GV", "source": "G04554UL", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G04554UL", "source": "G91365ZQ", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60782IE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01935FK", "dp": 10 } ], "links": [ { "target": "G60782IE", "source": "G01935FK", "residue_affected": { "residue_id": "N483", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G01935FK", "source": "G36191CD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60785FE", "notes": [ "reducing end mismatch [o-D-GlcNAc]", "homologous pathway end-point [G83717YJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G83717YJ", "dp": 9 }, { "id": "G60785FE", "dp": 9 } ], "links": [ { "target": "G60785FE", "source": "G83717YJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G83717YJ", "source": "G10219AA", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60814ZB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 }, { "id": "G28106CM", "dp": 17 } ], "links": [ { "target": "G60814ZB", "source": "G28106CM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60829NM", "notes": [], "error": "No pathways for [G60829NM] could be generated at this time" }, { "glytoucan_ac": "G60860OP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G60860OP] could be generated at this time" }, { "glytoucan_ac": "G60875XB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G16828VN]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G60875XB", "dp": 9 } ], "links": [ { "target": "G60875XB", "source": "G16828VN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60887NT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G91208VE", "dp": 9 }, { "id": "G58422UX", "dp": 10 } ], "links": [ { "target": "G60887NT", "source": "G58422UX", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G58422UX", "source": "G91208VE", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60926LS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G71690HK", "dp": 10 }, { "id": "G39298RF", "dp": 11 } ], "links": [ { "target": "G60926LS", "source": "G39298RF", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39298RF", "source": "G71690HK", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G71690HK", "source": "G61207RZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60926SE", "notes": [], "error": "No pathways for [G60926SE] could be generated at this time" }, { "glytoucan_ac": "G60929YB", "notes": [], "error": "No pathways for [G60929YB] could be generated at this time" }, { "glytoucan_ac": "G60941RE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 } ], "links": [ { "target": "G60941RE", "source": "G75185NU", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60956VN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30159WR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G60956VN", "dp": 9 } ], "links": [ { "target": "G60956VN", "source": "G30159WR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G60963AS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 }, { "id": "G65796FM", "dp": 13 } ], "links": [ { "target": "G60963AS", "source": "G65796FM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G65796FM", "source": "G79344MI", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61008CN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G21246OH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G21246OH", "dp": 11 }, { "id": "G61008CN", "dp": 11 } ], "links": [ { "target": "G61008CN", "source": "G21246OH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21246OH", "source": "G00176HZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61071ZB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G38208CY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G61684ET", "dp": 12 }, { "id": "G38208CY", "dp": 13 }, { "id": "G61071ZB", "dp": 13 } ], "links": [ { "target": "G61071ZB", "source": "G38208CY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38208CY", "source": "G61684ET", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G61684ET", "source": "G25520XG", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61086WG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54260SD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61086WG", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G61088TM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 } ], "links": [ { "target": "G61088TM", "source": "G90870DG", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61153TX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G61203OK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G61203OK] could be generated at this time" }, { "glytoucan_ac": "G61207RZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 } ], "links": [ { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61250GU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G62619LG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61250GU", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G61283FH", "notes": [], "error": "No pathways for [G61283FH] could be generated at this time" }, { "glytoucan_ac": "G61312PU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 }, { "id": "G01010HW", "dp": 9 }, { "id": "G11588II", "dp": 10 } ], "links": [ { "target": "G61312PU", "source": "G11588II", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G11588II", "source": "G01010HW", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61334IA", "notes": [], "error": "No pathways for [G61334IA] could be generated at this time" }, { "glytoucan_ac": "G61434JL", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G17213JF", "dp": 11 }, { "id": "G61530CE", "dp": 12 } ], "links": [ { "target": "G61434JL", "source": "G61530CE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G61530CE", "source": "G17213JF", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61456PF", "notes": [], "error": "No pathways for [G61456PF] could be generated at this time" }, { "glytoucan_ac": "G61457CY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11509RN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G11509RN", "dp": 12 }, { "id": "G61457CY", "dp": 12 } ], "links": [ { "target": "G61457CY", "source": "G11509RN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11509RN", "source": "G30302VM", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61519GA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G22098NU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G22098NU", "dp": 11 }, { "id": "G61519GA", "dp": 11 } ], "links": [ { "target": "G61519GA", "source": "G22098NU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G22098NU", "source": "G71013KY", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61530CE", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G17213JF", "dp": 11 } ], "links": [ { "target": "G61530CE", "source": "G17213JF", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61539GW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G60215UL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G47175EF", "dp": 11 }, { "id": "G60215UL", "dp": 12 }, { "id": "G61539GW", "dp": 12 } ], "links": [ { "target": "G61539GW", "source": "G60215UL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60215UL", "source": "G47175EF", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61551YB", "notes": [], "error": "No pathways for [G61551YB] could be generated at this time" }, { "glytoucan_ac": "G61553DD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G61553DD", "source": "G29011JC", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61575RT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 } ], "links": [ { "target": "G61575RT", "source": "G82050MN", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61601ZZ", "notes": [], "error": "No pathways for [G61601ZZ] could be generated at this time" }, { "glytoucan_ac": "G61614JZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86270DU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G86270DU", "dp": 12 }, { "id": "G61614JZ", "dp": 12 } ], "links": [ { "target": "G61614JZ", "source": "G86270DU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86270DU", "source": "G11041DA", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61640TZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G90725ZC", "dp": 9 } ], "links": [ { "target": "G61640TZ", "source": "G90725ZC", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G90725ZC", "source": "G89993FE", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61684ET", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G61684ET", "source": "G25520XG", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61702UX", "notes": [], "error": "No pathways for [G61702UX] could be generated at this time" }, { "glytoucan_ac": "G61705AR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G83402YY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61705AR", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G61706MD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G36191CD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G61706MD", "dp": 9 } ], "links": [ { "target": "G61706MD", "source": "G36191CD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61707PW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 }, { "id": "G74928QN", "dp": 14 } ], "links": [ { "target": "G61707PW", "source": "G74928QN", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G74928QN", "source": "G29449JO", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61717JN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G12398HZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G61717JN", "dp": 8 } ], "links": [ { "target": "G61717JN", "source": "G12398HZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61718TK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 } ], "links": [ { "target": "G61718TK", "source": "G43694RQ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61751GZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G61751GZ] could be generated at this time" }, { "glytoucan_ac": "G61819UR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03962UN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G03962UN", "dp": 9 }, { "id": "G61819UR", "dp": 9 } ], "links": [ { "target": "G61819UR", "source": "G03962UN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03962UN", "source": "G43677TG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61842MB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G61846BY", "notes": [], "error": "No pathways for [G61846BY] could be generated at this time" }, { "glytoucan_ac": "G61866NY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G90348RI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G90348RI", "dp": 12 }, { "id": "G61866NY", "dp": 12 } ], "links": [ { "target": "G61866NY", "source": "G90348RI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90348RI", "source": "G11041DA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61878VZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G95542JQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61878VZ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G61903HE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36268TW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 }, { "id": "G36268TW", "dp": 12 }, { "id": "G61903HE", "dp": 12 } ], "links": [ { "target": "G61903HE", "source": "G36268TW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36268TW", "source": "G77252PU", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61941WO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G48767NV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G48767NV", "dp": 14 }, { "id": "G61941WO", "dp": 14 } ], "links": [ { "target": "G61941WO", "source": "G48767NV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G48767NV", "source": "G53812BX", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61956VN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G70945OS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 }, { "id": "G70945OS", "dp": 13 }, { "id": "G61956VN", "dp": 13 } ], "links": [ { "target": "G61956VN", "source": "G70945OS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70945OS", "source": "G41331JX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G61970XW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G61970XW] could be generated at this time" }, { "glytoucan_ac": "G62048AU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G44504SC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G44504SC", "dp": 10 }, { "id": "G62048AU", "dp": 10 } ], "links": [ { "target": "G62048AU", "source": "G44504SC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44504SC", "source": "G20030CU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62112AO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06209KS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G06209KS", "dp": 8 }, { "id": "G62112AO", "dp": 8 } ], "links": [ { "target": "G62112AO", "source": "G06209KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06209KS", "source": "G69411IG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62145FH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G48109OV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G62145FH", "dp": 24 } ], "links": [] } , { "glytoucan_ac": "G62167DK", "notes": [], "error": "No pathways for [G62167DK] could be generated at this time" }, { "glytoucan_ac": "G62196IB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78011JO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G62196IB", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G62307SM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 }, { "id": "G14488UY", "dp": 15 } ], "links": [ { "target": "G62307SM", "source": "G14488UY", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G14488UY", "source": "G60564DP", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62326NX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G62326NX] could be generated at this time" }, { "glytoucan_ac": "G62333MG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06581HO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G06581HO", "dp": 12 }, { "id": "G62333MG", "dp": 12 } ], "links": [ { "target": "G62333MG", "source": "G06581HO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06581HO", "source": "G71679MX", "residue_affected": { "residue_id": "N59", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62349ZP", "notes": [], "error": "No pathways for [G62349ZP] could be generated at this time" }, { "glytoucan_ac": "G62360SN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G62364JZ", "notes": [], "error": "No pathways for [G62364JZ] could be generated at this time" }, { "glytoucan_ac": "G62387ZO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G14047PA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G14047PA", "dp": 11 }, { "id": "G62387ZO", "dp": 11 } ], "links": [ { "target": "G62387ZO", "source": "G14047PA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14047PA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62389NM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G62389NM] could be generated at this time" }, { "glytoucan_ac": "G62446JD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G90725ZC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G90725ZC", "dp": 9 }, { "id": "G62446JD", "dp": 9 } ], "links": [ { "target": "G62446JD", "source": "G90725ZC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90725ZC", "source": "G89993FE", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62447TX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G62447TX] could be generated at this time" }, { "glytoucan_ac": "G62464EH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45603BW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G45603BW", "dp": 14 }, { "id": "G62464EH", "dp": 14 } ], "links": [ { "target": "G62464EH", "source": "G45603BW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45603BW", "source": "G56549DH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62470WX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G62488UG", "notes": [], "error": "No pathways for [G62488UG] could be generated at this time" }, { "glytoucan_ac": "G62504BU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62517DC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78155FK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 }, { "id": "G62517DC", "dp": 10 } ], "links": [ { "target": "G62517DC", "source": "G78155FK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62519IY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36581MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G62519IY", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G62527ZD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G62553AU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G64789SR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G62553AU", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G62592GA", "notes": [], "error": "No pathways for [G62592GA] could be generated at this time" }, { "glytoucan_ac": "G62606MC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30293NE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G62606MC", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G62619LG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G62619LG] could be generated at this time" }, { "glytoucan_ac": "G62746IY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13322RS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G62746IY", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G62765SF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 } ], "links": [ { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62779OI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G87073UP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G62779OI", "dp": 10 } ], "links": [ { "target": "G62779OI", "source": "G87073UP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62781GE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14998UC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 }, { "id": "G14998UC", "dp": 12 }, { "id": "G62781GE", "dp": 12 } ], "links": [ { "target": "G62781GE", "source": "G14998UC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14998UC", "source": "G25140TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62798PI", "notes": [], "error": "No pathways for [G62798PI] could be generated at this time" }, { "glytoucan_ac": "G62808KR", "notes": [], "error": "No pathways for [G62808KR] could be generated at this time" }, { "glytoucan_ac": "G62826CL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 } ], "links": [ { "target": "G62826CL", "source": "G80858MF", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62836JK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84330VA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G62836JK", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G62880PC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 } ], "links": [ { "target": "G62880PC", "source": "G59471TH", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62883YA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 } ], "links": [ { "target": "G62883YA", "source": "G66866LE", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62945MQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G78503JC", "dp": 12 }, { "id": "G86202BL", "dp": 13 } ], "links": [ { "target": "G62945MQ", "source": "G86202BL", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G86202BL", "source": "G78503JC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62955ZH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G62968IF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G63889NK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G62968IF", "dp": 14 } ], "links": [ { "target": "G62968IF", "source": "G63889NK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62973JK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30651IU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 }, { "id": "G62973JK", "dp": 13 } ], "links": [ { "target": "G62973JK", "source": "G30651IU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G62989HM", "notes": [], "error": "No pathways for [G62989HM] could be generated at this time" }, { "glytoucan_ac": "G62989ND", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G63024BG", "notes": [], "error": "No pathways for [G63024BG] could be generated at this time" }, { "glytoucan_ac": "G63035DM", "notes": [], "error": "No pathways for [G63035DM] could be generated at this time" }, { "glytoucan_ac": "G63065KG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G63065KG] could be generated at this time" }, { "glytoucan_ac": "G63065ZE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94733WZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G94733WZ", "dp": 15 }, { "id": "G63065ZE", "dp": 15 } ], "links": [ { "target": "G63065ZE", "source": "G94733WZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94733WZ", "source": "G89877QI", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63075AF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G62880PC", "dp": 9 }, { "id": "G45686NF", "dp": 10 } ], "links": [ { "target": "G63075AF", "source": "G45686NF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45686NF", "source": "G62880PC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62880PC", "source": "G59471TH", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63078AB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G94363RH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 }, { "id": "G94363RH", "dp": 17 }, { "id": "G63078AB", "dp": 17 } ], "links": [ { "target": "G63078AB", "source": "G94363RH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94363RH", "source": "G79950YS", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63100CN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G63125IE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G94163JZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G63125IE", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G63142AA", "notes": [], "error": "No pathways for [G63142AA] could be generated at this time" }, { "glytoucan_ac": "G63166WT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 } ], "links": [ { "target": "G63166WT", "source": "G30302VM", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63170HT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G43664YB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G43664YB", "dp": 9 }, { "id": "G63170HT", "dp": 9 } ], "links": [ { "target": "G63170HT", "source": "G43664YB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43664YB", "source": "G24420RT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63208BT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G02679YX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G63208BT", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G63240YA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G44152CO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 }, { "id": "G44152CO", "dp": 11 }, { "id": "G63240YA", "dp": 11 } ], "links": [ { "target": "G63240YA", "source": "G44152CO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44152CO", "source": "G66866LE", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63308HG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G73977KO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G63308HG", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G63333DU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G16529MG", "dp": 14 } ], "links": [ { "target": "G63333DU", "source": "G16529MG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G16529MG", "source": "G56549DH", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63337DU", "notes": [], "error": "No pathways for [G63337DU] could be generated at this time" }, { "glytoucan_ac": "G63337SS", "notes": [], "error": "No pathways for [G63337SS] could be generated at this time" }, { "glytoucan_ac": "G63366CP", "notes": [], "error": "No pathways for [G63366CP] could be generated at this time" }, { "glytoucan_ac": "G63411NB", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G61751GZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G63411NB", "dp": 6 } ], "links": [ { "target": "G63411NB", "source": "G61751GZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G63413QV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66282NU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G63413QV", "dp": 13 } ], "links": [ { "target": "G63413QV", "source": "G66282NU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63480NF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72718TT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G63480NF", "dp": 9 } ], "links": [ { "target": "G63480NF", "source": "G72718TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63536HB", "notes": [], "error": "No pathways for [G63536HB] could be generated at this time" }, { "glytoucan_ac": "G63547QM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G57955DP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 }, { "id": "G63547QM", "dp": 15 } ], "links": [ { "target": "G63547QM", "source": "G57955DP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63565MO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69982RY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G69982RY", "dp": 11 }, { "id": "G63565MO", "dp": 11 } ], "links": [ { "target": "G63565MO", "source": "G69982RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69982RY", "source": "G45560HM", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63574RK", "notes": [], "error": "No pathways for [G63574RK] could be generated at this time" }, { "glytoucan_ac": "G63585HN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 } ], "links": [ { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63596DU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G63596DU] could be generated at this time" }, { "glytoucan_ac": "G63617UP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47554EG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G63617UP", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G63644AZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G63644AZ", "source": "G18938DW", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63659FK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G63665MU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59746QC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G59746QC", "dp": 14 }, { "id": "G63665MU", "dp": 14 } ], "links": [ { "target": "G63665MU", "source": "G59746QC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59746QC", "source": "G00909PI", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63681JP", "notes": [], "error": "No pathways for [G63681JP] could be generated at this time" }, { "glytoucan_ac": "G63699VG", "notes": [], "error": "No pathways for [G63699VG] could be generated at this time" }, { "glytoucan_ac": "G63708BZ", "notes": [], "error": "No pathways for [G63708BZ] could be generated at this time" }, { "glytoucan_ac": "G63710WS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G95898GD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 }, { "id": "G63710WS", "dp": 13 } ], "links": [ { "target": "G63710WS", "source": "G95898GD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63712AL", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G26844MI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G63712AL", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G63714PL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G25350TT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G59361OW", "dp": 11 }, { "id": "G25350TT", "dp": 12 }, { "id": "G63714PL", "dp": 12 } ], "links": [ { "target": "G63714PL", "source": "G25350TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25350TT", "source": "G59361OW", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59361OW", "source": "G44946WH", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63720BV", "notes": [], "error": "No pathways for [G63720BV] could be generated at this time" }, { "glytoucan_ac": "G63734KU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 } ], "links": [ { "target": "G63734KU", "source": "G32201IL", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63782AK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G03385XG", "dp": 13 } ], "links": [ { "target": "G63782AK", "source": "G03385XG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G03385XG", "source": "G01669LU", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63787RZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 } ], "links": [ { "target": "G63787RZ", "source": "G27919IH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63820GM", "notes": [], "error": "No pathways for [G63820GM] could be generated at this time" }, { "glytoucan_ac": "G63821SF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36176RV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G36176RV", "dp": 12 }, { "id": "G63821SF", "dp": 12 } ], "links": [ { "target": "G63821SF", "source": "G36176RV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36176RV", "source": "G30302VM", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63838JW", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G30588SI", "dp": 9 } ], "links": [ { "target": "G63838JW", "source": "G30588SI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30588SI", "source": "G08520NM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63889NK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 } ], "links": [ { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63899VB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G90223GH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G90223GH", "dp": 9 }, { "id": "G63899VB", "dp": 9 } ], "links": [ { "target": "G63899VB", "source": "G90223GH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90223GH", "source": "G29011JC", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63902MT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G33241WC", "dp": 15 } ], "links": [ { "target": "G63902MT", "source": "G33241WC", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G33241WC", "source": "G45720CA", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G63919RG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60419KX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G96963QG", "dp": 12 }, { "id": "G73759SD", "dp": 13 }, { "id": "G60419KX", "dp": 14 }, { "id": "G63919RG", "dp": 14 } ], "links": [ { "target": "G63919RG", "source": "G60419KX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60419KX", "source": "G73759SD", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G73759SD", "source": "G96963QG", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64048GU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45720CA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G64048GU", "dp": 14 } ], "links": [ { "target": "G64048GU", "source": "G45720CA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64077VW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G64077VW] could be generated at this time" }, { "glytoucan_ac": "G64098LT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14767DF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G14767DF", "dp": 8 }, { "id": "G64098LT", "dp": 8 } ], "links": [ { "target": "G64098LT", "source": "G14767DF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14767DF", "source": "G69411IG", "residue_affected": { "residue_id": "N205", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64098MP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 } ], "links": [ { "target": "G64098MP", "source": "G10691MJ", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64127GJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G78661LW", "dp": 11 }, { "id": "G24767EG", "dp": 12 } ], "links": [ { "target": "G64127GJ", "source": "G24767EG", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G24767EG", "source": "G78661LW", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78661LW", "source": "G32201IL", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64175SO", "notes": [], "error": "No pathways for [G64175SO] could be generated at this time" }, { "glytoucan_ac": "G64261IK", "notes": [], "error": "No pathways for [G64261IK] could be generated at this time" }, { "glytoucan_ac": "G64271PC", "notes": [], "error": "No pathways for [G64271PC] could be generated at this time" }, { "glytoucan_ac": "G64324VB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 } ], "links": [ { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64330NA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19242QH]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G64330NA", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G64334QQ", "notes": [], "error": "No pathways for [G64334QQ] could be generated at this time" }, { "glytoucan_ac": "G64343WH", "notes": [], "error": "No pathways for [G64343WH] could be generated at this time" }, { "glytoucan_ac": "G64357NA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G38291RB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G38291RB", "dp": 13 }, { "id": "G64357NA", "dp": 13 } ], "links": [ { "target": "G64357NA", "source": "G38291RB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38291RB", "source": "G45359RY", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64389UN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G72919IM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G64389UN", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G64398GR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G67173FM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G64398GR", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G64418SR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69912LP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G41720HN", "dp": 8 }, { "id": "G69912LP", "dp": 9 }, { "id": "G64418SR", "dp": 9 } ], "links": [ { "target": "G64418SR", "source": "G69912LP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69912LP", "source": "G41720HN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G41720HN", "source": "G07483YN", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64468KS", "notes": [], "error": "No pathways for [G64468KS] could be generated at this time" }, { "glytoucan_ac": "G64481DJ", "notes": [], "error": "No pathways for [G64481DJ] could be generated at this time" }, { "glytoucan_ac": "G64501OO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G64518MK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G41720HN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G41720HN", "dp": 8 }, { "id": "G64518MK", "dp": 8 } ], "links": [ { "target": "G64518MK", "source": "G41720HN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41720HN", "source": "G07483YN", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64538ZR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G35096EN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G35096EN", "dp": 10 }, { "id": "G64538ZR", "dp": 10 } ], "links": [ { "target": "G64538ZR", "source": "G35096EN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G35096EN", "source": "G20030CU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64582TJ", "notes": [], "error": "No pathways for [G64582TJ] could be generated at this time" }, { "glytoucan_ac": "G64586PM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G64586PM] could be generated at this time" }, { "glytoucan_ac": "G64618XR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G64618XR] could be generated at this time" }, { "glytoucan_ac": "G64633BH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 } ], "links": [ { "target": "G64633BH", "source": "G79348ZY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64652EG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 } ], "links": [ { "target": "G64652EG", "source": "G92024SL", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64661YG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G85767HW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 }, { "id": "G64661YG", "dp": 10 } ], "links": [ { "target": "G64661YG", "source": "G85767HW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64662SH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88127MB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G64662SH", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G64666BO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G09576QH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G64666BO", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G64669AQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 } ], "links": [ { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G64693IG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G64697JB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 } ], "links": [ { "target": "G64697JB", "source": "G12740VA", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64713KE", "notes": [], "error": "No pathways for [G64713KE] could be generated at this time" }, { "glytoucan_ac": "G64725VJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G61088TM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G61088TM", "dp": 12 }, { "id": "G64725VJ", "dp": 12 } ], "links": [ { "target": "G64725VJ", "source": "G61088TM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61088TM", "source": "G90870DG", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64741WD", "notes": [], "error": "No pathways for [G64741WD] could be generated at this time" }, { "glytoucan_ac": "G64761FU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G64761FU] could be generated at this time" }, { "glytoucan_ac": "G64789SR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G64789SR] could be generated at this time" }, { "glytoucan_ac": "G64803AP", "notes": [], "error": "No pathways for [G64803AP] could be generated at this time" }, { "glytoucan_ac": "G64803HZ", "notes": [], "error": "No pathways for [G64803HZ] could be generated at this time" }, { "glytoucan_ac": "G64813JD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G17437BX", "dp": 14 } ], "links": [ { "target": "G64813JD", "source": "G17437BX", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G17437BX", "source": "G92359VA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64823DM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G64827NU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G64827NU", "source": "G29857RC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64850DY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G46021KV", "dp": 12 } ], "links": [ { "target": "G64850DY", "source": "G46021KV", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G46021KV", "source": "G29857RC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64856PW", "notes": [], "error": "No pathways for [G64856PW] could be generated at this time" }, { "glytoucan_ac": "G64857LW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59989VG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G64857LW", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G64860JV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56591LC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 }, { "id": "G64860JV", "dp": 10 } ], "links": [ { "target": "G64860JV", "source": "G56591LC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64894MA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59742GY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G64894MA", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G64897QL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G61707PW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 }, { "id": "G74928QN", "dp": 14 }, { "id": "G61707PW", "dp": 15 }, { "id": "G64897QL", "dp": 15 } ], "links": [ { "target": "G64897QL", "source": "G61707PW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61707PW", "source": "G74928QN", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G74928QN", "source": "G29449JO", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G64936OS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G64950NP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G64950NP] could be generated at this time" }, { "glytoucan_ac": "G64965ZH", "notes": [], "error": "No pathways for [G64965ZH] could be generated at this time" }, { "glytoucan_ac": "G64979EW", "notes": [], "error": "No pathways for [G64979EW] could be generated at this time" }, { "glytoucan_ac": "G65009JH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G21459ST]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G65009JH", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G65030HB", "notes": [], "error": "No pathways for [G65030HB] could be generated at this time" }, { "glytoucan_ac": "G65079ZY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G90564EX", "dp": 11 }, { "id": "G08949VK", "dp": 12 }, { "id": "G12450CJ", "dp": 13 } ], "links": [ { "target": "G65079ZY", "source": "G12450CJ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12450CJ", "source": "G08949VK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G08949VK", "source": "G90564EX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90564EX", "source": "G28826SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65117HG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G29676WX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G06216UH", "dp": 10 }, { "id": "G49743VF", "dp": 11 }, { "id": "G29676WX", "dp": 12 }, { "id": "G65117HG", "dp": 12 } ], "links": [ { "target": "G65117HG", "source": "G29676WX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29676WX", "source": "G49743VF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G49743VF", "source": "G06216UH", "residue_affected": { "residue_id": "N470", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65226QM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52483OL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G65226QM", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G65239SF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 } ], "links": [ { "target": "G65239SF", "source": "G81923ER", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65243FP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84390MS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G65243FP", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G65294YU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82252QI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G65294YU", "dp": 11 } ], "links": [ { "target": "G65294YU", "source": "G82252QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65296TL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 } ], "links": [ { "target": "G65296TL", "source": "G50774CV", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65299LG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G20924UR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G65299LG", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G65307KA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 } ], "links": [ { "target": "G65307KA", "source": "G10691MJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65340BF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03727RK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G03727RK", "dp": 14 }, { "id": "G65340BF", "dp": 14 } ], "links": [ { "target": "G65340BF", "source": "G03727RK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03727RK", "source": "G66282NU", "residue_affected": { "residue_id": "N251", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65356DX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19843TY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G19843TY", "dp": 10 }, { "id": "G65356DX", "dp": 10 } ], "links": [ { "target": "G65356DX", "source": "G19843TY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19843TY", "source": "G27919IH", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65370RS", "notes": [], "error": "No pathways for [G65370RS] could be generated at this time" }, { "glytoucan_ac": "G65380CT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G65380CT] could be generated at this time" }, { "glytoucan_ac": "G65415JG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G29011JC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G65415JG", "dp": 8 } ], "links": [ { "target": "G65415JG", "source": "G29011JC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65419YA", "notes": [], "error": "No pathways for [G65419YA] could be generated at this time" }, { "glytoucan_ac": "G65447JX", "notes": [], "error": "No pathways for [G65447JX] could be generated at this time" }, { "glytoucan_ac": "G65449BO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G36519NW", "dp": 13 } ], "links": [ { "target": "G65449BO", "source": "G36519NW", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G36519NW", "source": "G01669LU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65464PI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61718TK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G61718TK", "dp": 11 }, { "id": "G65464PI", "dp": 11 } ], "links": [ { "target": "G65464PI", "source": "G61718TK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61718TK", "source": "G43694RQ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65500VO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G85213FQ", "dp": 7 } ], "links": [ { "target": "G65500VO", "source": "G85213FQ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G85213FQ", "source": "G61751GZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G65508FE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G65508FE] could be generated at this time" }, { "glytoucan_ac": "G65515HD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G48802KI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G48802KI", "dp": 9 }, { "id": "G65515HD", "dp": 9 } ], "links": [ { "target": "G65515HD", "source": "G48802KI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G48802KI", "source": "G43677TG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65518IK", "notes": [], "error": "No pathways for [G65518IK] could be generated at this time" }, { "glytoucan_ac": "G65593RU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G15727JK", "dp": 8 } ], "links": [ { "target": "G65593RU", "source": "G15727JK", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G15727JK", "source": "G69411IG", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65597BI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65603XA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G80352NL", "dp": 14 } ], "links": [ { "target": "G65603XA", "source": "G80352NL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G80352NL", "source": "G66282NU", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65617KZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43665PB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G79556AB", "dp": 12 }, { "id": "G43665PB", "dp": 13 }, { "id": "G65617KZ", "dp": 13 } ], "links": [ { "target": "G65617KZ", "source": "G43665PB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43665PB", "source": "G79556AB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79556AB", "source": "G82252QI", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65680SX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 } ], "links": [ { "target": "G65680SX", "source": "G08863NS", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65697SK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66866LE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 }, { "id": "G65697SK", "dp": 10 } ], "links": [ { "target": "G65697SK", "source": "G66866LE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65703ID", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08340FW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G08340FW", "dp": 8 }, { "id": "G65703ID", "dp": 8 } ], "links": [ { "target": "G65703ID", "source": "G08340FW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08340FW", "source": "G39089YD", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G65721TS", "notes": [], "error": "No pathways for [G65721TS] could be generated at this time" }, { "glytoucan_ac": "G65760UO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G65761WK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G07392QY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G07392QY", "dp": 11 }, { "id": "G65761WK", "dp": 11 } ], "links": [ { "target": "G65761WK", "source": "G07392QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07392QY", "source": "G78059CC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65796FM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 } ], "links": [ { "target": "G65796FM", "source": "G79344MI", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65799WV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32156DB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G80661IW", "dp": 10 }, { "id": "G32156DB", "dp": 11 }, { "id": "G65799WV", "dp": 11 } ], "links": [ { "target": "G65799WV", "source": "G32156DB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32156DB", "source": "G80661IW", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G80661IW", "source": "G46638GC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65825CX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31604HF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G31604HF", "dp": 8 }, { "id": "G65825CX", "dp": 8 } ], "links": [ { "target": "G65825CX", "source": "G31604HF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31604HF", "source": "G07483YN", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65832JS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G65832JS] could be generated at this time" }, { "glytoucan_ac": "G65840VR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G65850ES", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G65850ES] could be generated at this time" }, { "glytoucan_ac": "G65855MN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76807JB]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G65855MN", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G65867II", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G65867II] could be generated at this time" }, { "glytoucan_ac": "G65890UA", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G65890UA", "source": "G16828VN", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65893EZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82942ZJ]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G82942ZJ", "dp": 9 }, { "id": "G65893EZ", "dp": 9 } ], "links": [ { "target": "G65893EZ", "source": "G82942ZJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82942ZJ", "source": "G08520NM", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65937EW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G12398HZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G65937EW", "dp": 8 } ], "links": [ { "target": "G65937EW", "source": "G12398HZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65948NJ", "notes": [], "error": "No pathways for [G65948NJ] could be generated at this time" }, { "glytoucan_ac": "G65981EG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G37385TT", "dp": 11 } ], "links": [ { "target": "G65981EG", "source": "G37385TT", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G37385TT", "source": "G88417ED", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G65984FE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80858MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G65984FE", "dp": 8 } ], "links": [ { "target": "G65984FE", "source": "G80858MF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66016NA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66016NA] could be generated at this time" }, { "glytoucan_ac": "G66044FT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G66098KC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G66098KC", "source": "G18938DW", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66106WQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03754YM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G66106WQ", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G66111ZR", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G91365ZQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G66111ZR", "dp": 10 } ], "links": [ { "target": "G66111ZR", "source": "G91365ZQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66118UZ", "notes": [], "error": "No pathways for [G66118UZ] could be generated at this time" }, { "glytoucan_ac": "G66121LF", "notes": [], "error": "No pathways for [G66121LF] could be generated at this time" }, { "glytoucan_ac": "G66122ZT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G68946DB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G76528ZS", "dp": 11 }, { "id": "G68946DB", "dp": 12 }, { "id": "G66122ZT", "dp": 12 } ], "links": [ { "target": "G66122ZT", "source": "G68946DB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G68946DB", "source": "G76528ZS", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G76528ZS", "source": "G52934AK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66129DI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G03275SD", "dp": 10 } ], "links": [ { "target": "G66129DI", "source": "G03275SD", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66153IB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G47975JA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G47975JA", "dp": 12 }, { "id": "G66153IB", "dp": 12 } ], "links": [ { "target": "G66153IB", "source": "G47975JA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47975JA", "source": "G11041DA", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66190PM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 } ], "links": [ { "target": "G66190PM", "source": "G78155FK", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66193EV", "notes": [], "error": "No pathways for [G66193EV] could be generated at this time" }, { "glytoucan_ac": "G66204OA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 } ], "links": [ { "target": "G66204OA", "source": "G39089YD", "residue_affected": { "residue_id": "N477", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylf", "full_name": "β-D-Xylf" }, "effect": "Adds β-D-Xylf", "enzymes": [] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G66215MG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66215MG] could be generated at this time" }, { "glytoucan_ac": "G66257KQ", "notes": [], "error": "No pathways for [G66257KQ] could be generated at this time" }, { "glytoucan_ac": "G66265KN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G33262YZ", "dp": 11 } ], "links": [ { "target": "G66265KN", "source": "G33262YZ", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G33262YZ", "source": "G52934AK", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66282NU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 } ], "links": [ { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66290TX", "notes": [], "error": "No pathways for [G66290TX] could be generated at this time" }, { "glytoucan_ac": "G66313YW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 } ], "links": [ { "target": "G66313YW", "source": "G74645FT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66348MF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59471TH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G66348MF", "dp": 8 } ], "links": [ { "target": "G66348MF", "source": "G59471TH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66362JB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G42438ZG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G66362JB", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G66368ZD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G04989WY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G66368ZD", "dp": 13 } ], "links": [ { "target": "G66368ZD", "source": "G04989WY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66375VY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47279LF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G66375VY", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G66408EY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66408EY] could be generated at this time" }, { "glytoucan_ac": "G66408GD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G11012KS", "dp": 12 } ], "links": [ { "target": "G66408GD", "source": "G11012KS", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G11012KS", "source": "G37046CZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66422NV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66422NV] could be generated at this time" }, { "glytoucan_ac": "G66471SN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G65307KA", "dp": 12 } ], "links": [ { "target": "G66471SN", "source": "G65307KA", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G65307KA", "source": "G10691MJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66474IG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G33909XJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 }, { "id": "G33909XJ", "dp": 11 }, { "id": "G66474IG", "dp": 11 } ], "links": [ { "target": "G66474IG", "source": "G33909XJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33909XJ", "source": "G81923ER", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66488GE", "notes": [], "error": "No pathways for [G66488GE] could be generated at this time" }, { "glytoucan_ac": "G66513RC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49307MQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G78276SQ", "dp": 12 }, { "id": "G49307MQ", "dp": 13 }, { "id": "G66513RC", "dp": 13 } ], "links": [ { "target": "G66513RC", "source": "G49307MQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49307MQ", "source": "G78276SQ", "residue_affected": { "residue_id": "N408", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G78276SQ", "source": "G11041DA", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66544RE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G78980OK]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G66544RE", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G66572SF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 } ], "links": [ { "target": "G66572SF", "source": "G48658PB", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66595IQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66595IQ] could be generated at this time" }, { "glytoucan_ac": "G66634LZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 } ], "links": [ { "target": "G66634LZ", "source": "G29492IF", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66653BX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G66655HQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G63585HN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 }, { "id": "G66655HQ", "dp": 11 } ], "links": [ { "target": "G66655HQ", "source": "G63585HN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66661ZY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88864RV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G66661ZY", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G66665YI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 } ], "links": [ { "target": "G66665YI", "source": "G66282NU", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66674JW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G17857ZF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 }, { "id": "G57970NA", "dp": 13 }, { "id": "G17857ZF", "dp": 14 }, { "id": "G66674JW", "dp": 14 } ], "links": [ { "target": "G66674JW", "source": "G17857ZF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17857ZF", "source": "G57970NA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G57970NA", "source": "G49515VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66689PB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66689PB] could be generated at this time" }, { "glytoucan_ac": "G66692CW", "notes": [], "error": "No pathways for [G66692CW] could be generated at this time" }, { "glytoucan_ac": "G66724VW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G83845ZV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G66724VW", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G66728LX", "notes": [], "error": "No pathways for [G66728LX] could be generated at this time" }, { "glytoucan_ac": "G66741YQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36191CD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G66741YQ", "dp": 9 } ], "links": [ { "target": "G66741YQ", "source": "G36191CD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66765ZA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66765ZA] could be generated at this time" }, { "glytoucan_ac": "G66846ML", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G84777MO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G66846ML", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G66847YI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G66847YI] could be generated at this time" }, { "glytoucan_ac": "G66866LE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 } ], "links": [ { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66932MV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99866WK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G38395YJ", "dp": 14 }, { "id": "G99866WK", "dp": 15 }, { "id": "G66932MV", "dp": 15 } ], "links": [ { "target": "G66932MV", "source": "G99866WK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99866WK", "source": "G38395YJ", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G38395YJ", "source": "G00909PI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66937TJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66942CJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23345GE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G42686NQ", "dp": 14 }, { "id": "G23345GE", "dp": 15 }, { "id": "G66942CJ", "dp": 15 } ], "links": [ { "target": "G66942CJ", "source": "G23345GE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23345GE", "source": "G42686NQ", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G42686NQ", "source": "G19726AG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66963AS", "notes": [], "error": "No pathways for [G66963AS] could be generated at this time" }, { "glytoucan_ac": "G66964CR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G17168RO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 }, { "id": "G66964CR", "dp": 14 } ], "links": [ { "target": "G66964CR", "source": "G17168RO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G66992XO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G67042FO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79302PB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67042FO", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G67045LB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67066JI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52663AD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G67066JI", "dp": 9 } ], "links": [ { "target": "G67066JI", "source": "G52663AD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67079AO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17740GV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G17740GV", "dp": 15 }, { "id": "G67079AO", "dp": 15 } ], "links": [ { "target": "G67079AO", "source": "G17740GV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17740GV", "source": "G89877QI", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67118IN", "notes": [], "error": "No pathways for [G67118IN] could be generated at this time" }, { "glytoucan_ac": "G67167QM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G85213FQ", "dp": 7 } ], "links": [ { "target": "G67167QM", "source": "G85213FQ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G85213FQ", "source": "G61751GZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G67173FM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G67173FM] could be generated at this time" }, { "glytoucan_ac": "G67215MI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 } ], "links": [ { "target": "G67215MI", "source": "G11637WL", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67223RN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G95989NQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67223RN", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G67226SQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 }, { "id": "G41389FB", "dp": 11 } ], "links": [ { "target": "G67226SQ", "source": "G41389FB", "residue_affected": { "residue_id": "N483", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G41389FB", "source": "G65597BI", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67269NB", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G67269NB] could be generated at this time" }, { "glytoucan_ac": "G67342MA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G70708LW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 }, { "id": "G70708LW", "dp": 12 }, { "id": "G67342MA", "dp": 12 } ], "links": [ { "target": "G67342MA", "source": "G70708LW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70708LW", "source": "G74675FC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67358EC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G67362UI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G83541HL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67362UI", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G67410LQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G67410LQ] could be generated at this time" }, { "glytoucan_ac": "G67411ST", "notes": [], "error": "No pathways for [G67411ST] could be generated at this time" }, { "glytoucan_ac": "G67413BG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94876HV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67413BG", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G67465JK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G67465JK] could be generated at this time" }, { "glytoucan_ac": "G67505LV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G49915LA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67505LV", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G67534LV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G60963AS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 }, { "id": "G79344MI", "dp": 12 }, { "id": "G65796FM", "dp": 13 }, { "id": "G60963AS", "dp": 14 }, { "id": "G67534LV", "dp": 14 } ], "links": [ { "target": "G67534LV", "source": "G60963AS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60963AS", "source": "G65796FM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G65796FM", "source": "G79344MI", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67536FA", "notes": [], "error": "No pathways for [G67536FA] could be generated at this time" }, { "glytoucan_ac": "G67549HD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G67549HD] could be generated at this time" }, { "glytoucan_ac": "G67608DN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74264KM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67608DN", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G67610IY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58281SK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G58281SK", "dp": 9 }, { "id": "G67610IY", "dp": 9 } ], "links": [ { "target": "G67610IY", "source": "G58281SK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G58281SK", "source": "G59471TH", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67612NO", "notes": [], "error": "No pathways for [G67612NO] could be generated at this time" }, { "glytoucan_ac": "G67623NK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G89877QI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G67623NK", "dp": 14 } ], "links": [ { "target": "G67623NK", "source": "G89877QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67628PC", "notes": [], "error": "No pathways for [G67628PC] could be generated at this time" }, { "glytoucan_ac": "G67642SS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16155TD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G16155TD", "dp": 13 }, { "id": "G67642SS", "dp": 13 } ], "links": [ { "target": "G67642SS", "source": "G16155TD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16155TD", "source": "G01669LU", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67646EV", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G17213JF", "dp": 11 } ], "links": [ { "target": "G67646EV", "source": "G17213JF", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17213JF", "source": "G08187GM", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67660KD", "notes": [], "error": "No pathways for [G67660KD] could be generated at this time" }, { "glytoucan_ac": "G67715OS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G92024SL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G67715OS", "dp": 7 } ], "links": [ { "target": "G67715OS", "source": "G92024SL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67719WQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G48954CA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G48954CA", "dp": 9 }, { "id": "G67719WQ", "dp": 9 } ], "links": [ { "target": "G67719WQ", "source": "G48954CA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G48954CA", "source": "G12398HZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67728UJ", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G66634LZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G66634LZ", "dp": 9 }, { "id": "G67728UJ", "dp": 9 } ], "links": [ { "target": "G67728UJ", "source": "G66634LZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66634LZ", "source": "G29492IF", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67767BR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G02679YX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67767BR", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G67776JA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 } ], "links": [ { "target": "G67776JA", "source": "G29492IF", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67782JV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 } ], "links": [ { "target": "G67782JV", "source": "G35310KA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67855QE", "notes": [], "error": "No pathways for [G67855QE] could be generated at this time" }, { "glytoucan_ac": "G67898UK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57955DP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 }, { "id": "G67898UK", "dp": 15 } ], "links": [ { "target": "G67898UK", "source": "G57955DP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67915MO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11535IB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G11535IB", "dp": 9 }, { "id": "G67915MO", "dp": 9 } ], "links": [ { "target": "G67915MO", "source": "G11535IB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11535IB", "source": "G59471TH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67924FL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G16828VN]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G67924FL", "dp": 9 } ], "links": [ { "target": "G67924FL", "source": "G16828VN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67942CH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 } ], "links": [ { "target": "G67942CH", "source": "G71013KY", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G67943IR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G67943IR] could be generated at this time" }, { "glytoucan_ac": "G67954RA", "notes": [], "error": "No pathways for [G67954RA] could be generated at this time" }, { "glytoucan_ac": "G67978NC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G80717KS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G67978NC", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G68059HB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G24413UY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 }, { "id": "G24413UY", "dp": 11 }, { "id": "G68059HB", "dp": 11 } ], "links": [ { "target": "G68059HB", "source": "G24413UY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G24413UY", "source": "G78890OB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68080UR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G68080UR] could be generated at this time" }, { "glytoucan_ac": "G68140PE", "notes": [], "error": "No pathways for [G68140PE] could be generated at this time" }, { "glytoucan_ac": "G68175NA", "notes": [], "error": "No pathways for [G68175NA] could be generated at this time" }, { "glytoucan_ac": "G68189FR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G05307LM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G05307LM", "dp": 13 }, { "id": "G68189FR", "dp": 13 } ], "links": [ { "target": "G68189FR", "source": "G05307LM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G05307LM", "source": "G91023GB", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68194UU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36521AS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G91208VE", "dp": 9 }, { "id": "G36521AS", "dp": 10 }, { "id": "G68194UU", "dp": 10 } ], "links": [ { "target": "G68194UU", "source": "G36521AS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36521AS", "source": "G91208VE", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68203DZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59742GY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G68203DZ", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G68221KD", "notes": [], "error": "No pathways for [G68221KD] could be generated at this time" }, { "glytoucan_ac": "G68283NG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G68283NG] could be generated at this time" }, { "glytoucan_ac": "G68313WI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G68313WI] could be generated at this time" }, { "glytoucan_ac": "G68318SH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45560HM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G68318SH", "dp": 10 } ], "links": [ { "target": "G68318SH", "source": "G45560HM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68337CZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79565XA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G19469VZ", "dp": 18 }, { "id": "G79565XA", "dp": 19 }, { "id": "G68337CZ", "dp": 19 } ], "links": [ { "target": "G68337CZ", "source": "G79565XA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79565XA", "source": "G19469VZ", "residue_affected": { "residue_id": "N108", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G19469VZ", "source": "G92574YO", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68354TY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G54611ZT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G54611ZT", "dp": 11 }, { "id": "G68354TY", "dp": 11 } ], "links": [ { "target": "G68354TY", "source": "G54611ZT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68395LV", "notes": [], "error": "No pathways for [G68395LV] could be generated at this time" }, { "glytoucan_ac": "G68411DS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G68546CJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28826SH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G68546CJ", "dp": 10 } ], "links": [ { "target": "G68546CJ", "source": "G28826SH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68551IQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G21246OH", "dp": 11 } ], "links": [ { "target": "G68551IQ", "source": "G21246OH", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G21246OH", "source": "G00176HZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68572OG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98190RD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G98190RD", "dp": 11 }, { "id": "G68572OG", "dp": 11 } ], "links": [ { "target": "G68572OG", "source": "G98190RD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98190RD", "source": "G52934AK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68578NZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G80652ZF", "dp": 8 }, { "id": "G43654PQ", "dp": 9 } ], "links": [ { "target": "G68578NZ", "source": "G43654PQ", "residue_affected": { "residue_id": "N255", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43654PQ", "source": "G80652ZF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80652ZF", "source": "G39213VZ", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68651MF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86102AA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G86102AA", "dp": 11 }, { "id": "G68651MF", "dp": 11 } ], "links": [ { "target": "G68651MF", "source": "G86102AA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86102AA", "source": "G85542KD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68668TB", "notes": [], "error": "No pathways for [G68668TB] could be generated at this time" }, { "glytoucan_ac": "G68679LW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23626NI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G23626NI", "dp": 11 }, { "id": "G68679LW", "dp": 11 } ], "links": [ { "target": "G68679LW", "source": "G23626NI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23626NI", "source": "G85542KD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68758PE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G68758PE] could be generated at this time" }, { "glytoucan_ac": "G68765US", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G52880ZN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G52880ZN", "dp": 12 }, { "id": "G68765US", "dp": 12 } ], "links": [ { "target": "G68765US", "source": "G52880ZN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52880ZN", "source": "G82252QI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68774DG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G64633BH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G64633BH", "dp": 9 }, { "id": "G68774DG", "dp": 9 } ], "links": [ { "target": "G68774DG", "source": "G64633BH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G64633BH", "source": "G79348ZY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68795JE", "notes": [], "error": "No pathways for [G68795JE] could be generated at this time" }, { "glytoucan_ac": "G68801RI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30437YI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G68801RI", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G68803QA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10219AA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G68803QA", "dp": 8 } ], "links": [ { "target": "G68803QA", "source": "G10219AA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68804CO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G04273XP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G03385XG", "dp": 13 }, { "id": "G04273XP", "dp": 14 }, { "id": "G68804CO", "dp": 14 } ], "links": [ { "target": "G68804CO", "source": "G04273XP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04273XP", "source": "G03385XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G03385XG", "source": "G01669LU", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68817WF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07041CT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G97765TT", "dp": 12 }, { "id": "G07041CT", "dp": 13 }, { "id": "G68817WF", "dp": 13 } ], "links": [ { "target": "G68817WF", "source": "G07041CT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07041CT", "source": "G97765TT", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G97765TT", "source": "G18219CJ", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68845SP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G68845SP", "source": "G18938DW", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68892PJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G68892PJ] could be generated at this time" }, { "glytoucan_ac": "G68903PJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G68907ZA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41811VQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G68907ZA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G68912OX", "notes": [], "error": "No pathways for [G68912OX] could be generated at this time" }, { "glytoucan_ac": "G68915EJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G62826CL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G62826CL", "dp": 9 }, { "id": "G68915EJ", "dp": 9 } ], "links": [ { "target": "G68915EJ", "source": "G62826CL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62826CL", "source": "G80858MF", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68937TM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68946DB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G76528ZS", "dp": 11 } ], "links": [ { "target": "G68946DB", "source": "G76528ZS", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G76528ZS", "source": "G52934AK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68955EJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G68957QP", "notes": [], "error": "No pathways for [G68957QP] could be generated at this time" }, { "glytoucan_ac": "G68963BB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G45777DE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G26939ZY", "dp": 8 }, { "id": "G45777DE", "dp": 9 }, { "id": "G68963BB", "dp": 9 } ], "links": [ { "target": "G68963BB", "source": "G45777DE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45777DE", "source": "G26939ZY", "residue_affected": { "residue_id": "N305", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G26939ZY", "source": "G39213VZ", "residue_affected": { "residue_id": "N306", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G68985NT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G68991BW", "notes": [], "error": "No pathways for [G68991BW] could be generated at this time" }, { "glytoucan_ac": "G69018AJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G78661LW", "dp": 11 } ], "links": [ { "target": "G69018AJ", "source": "G78661LW", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78661LW", "source": "G32201IL", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69060LX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31010RQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G69060LX", "dp": 11 } ], "links": [ { "target": "G69060LX", "source": "G31010RQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69083KH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84874EV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 }, { "id": "G84874EV", "dp": 11 }, { "id": "G69083KH", "dp": 11 } ], "links": [ { "target": "G69083KH", "source": "G84874EV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84874EV", "source": "G99270AV", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69086TY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 } ], "links": [ { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69103XG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G96113SZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G82420SH", "dp": 10 }, { "id": "G96113SZ", "dp": 11 }, { "id": "G69103XG", "dp": 11 } ], "links": [ { "target": "G69103XG", "source": "G96113SZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96113SZ", "source": "G82420SH", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82420SH", "source": "G45262QY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69113LL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G32659RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G32659RY", "dp": 12 }, { "id": "G69113LL", "dp": 12 } ], "links": [ { "target": "G69113LL", "source": "G32659RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32659RY", "source": "G59877NF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69121YI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54956ME]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G69121YI", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G69137CP", "notes": [], "error": "No pathways for [G69137CP] could be generated at this time" }, { "glytoucan_ac": "G69159WK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G43694RQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G69159WK", "dp": 10 } ], "links": [ { "target": "G69159WK", "source": "G43694RQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69170UT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 } ], "links": [ { "target": "G69170UT", "source": "G82050MN", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69175BJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45262QY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G69175BJ", "dp": 9 } ], "links": [ { "target": "G69175BJ", "source": "G45262QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69319YQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79950YS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 }, { "id": "G69319YQ", "dp": 16 } ], "links": [ { "target": "G69319YQ", "source": "G79950YS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69332GG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G71690HK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G71690HK", "dp": 10 }, { "id": "G69332GG", "dp": 10 } ], "links": [ { "target": "G69332GG", "source": "G71690HK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71690HK", "source": "G61207RZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69337UU", "notes": [], "error": "No pathways for [G69337UU] could be generated at this time" }, { "glytoucan_ac": "G69381LS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G52483OL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G69381LS", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G69390GI", "notes": [], "error": "No pathways for [G69390GI] could be generated at this time" }, { "glytoucan_ac": "G69411IG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69458AV", "notes": [], "error": "No pathways for [G69458AV] could be generated at this time" }, { "glytoucan_ac": "G69461KL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G78059CC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G69461KL", "dp": 10 } ], "links": [ { "target": "G69461KL", "source": "G78059CC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69480BN", "notes": [], "error": "No pathways for [G69480BN] could be generated at this time" }, { "glytoucan_ac": "G69485SE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86928UZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 }, { "id": "G86928UZ", "dp": 11 }, { "id": "G69485SE", "dp": 11 } ], "links": [ { "target": "G69485SE", "source": "G86928UZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86928UZ", "source": "G85767HW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69533GA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10664FL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G10664FL", "dp": 10 }, { "id": "G69533GA", "dp": 10 } ], "links": [ { "target": "G69533GA", "source": "G10664FL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10664FL", "source": "G45262QY", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69576GO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G63787RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G63787RZ", "dp": 10 }, { "id": "G69576GO", "dp": 10 } ], "links": [ { "target": "G69576GO", "source": "G63787RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63787RZ", "source": "G27919IH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69584VD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61640TZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G90725ZC", "dp": 9 }, { "id": "G61640TZ", "dp": 10 }, { "id": "G69584VD", "dp": 10 } ], "links": [ { "target": "G69584VD", "source": "G61640TZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61640TZ", "source": "G90725ZC", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G90725ZC", "source": "G89993FE", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69600TI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 } ], "links": [ { "target": "G69600TI", "source": "G64669AQ", "residue_affected": { "residue_id": "N477", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylf", "full_name": "β-D-Xylf" }, "effect": "Adds β-D-Xylf", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G69672LF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G75120WS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G69672LF", "dp": 13 } ], "links": [ { "target": "G69672LF", "source": "G75120WS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69725KG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96921ZU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G96921ZU", "dp": 12 }, { "id": "G69725KG", "dp": 12 } ], "links": [ { "target": "G69725KG", "source": "G96921ZU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96921ZU", "source": "G11041DA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69738ZU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G83926PC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 }, { "id": "G01354KL", "dp": 14 }, { "id": "G83926PC", "dp": 15 }, { "id": "G69738ZU", "dp": 15 } ], "links": [ { "target": "G69738ZU", "source": "G83926PC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G83926PC", "source": "G01354KL", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01354KL", "source": "G41611UP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69749VJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G99935CU]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 }, { "id": "G99969SS", "dp": 10 }, { "id": "G99935CU", "dp": 11 }, { "id": "G69749VJ", "dp": 11 } ], "links": [ { "target": "G69749VJ", "source": "G99935CU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99935CU", "source": "G99969SS", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G99969SS", "source": "G13151XE", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69752OZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G45560HM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G69752OZ", "dp": 10 } ], "links": [ { "target": "G69752OZ", "source": "G45560HM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69753WV", "notes": [], "error": "No pathways for [G69753WV] could be generated at this time" }, { "glytoucan_ac": "G69758TR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G55974RB", "dp": 11 }, { "id": "G93707PO", "dp": 12 } ], "links": [ { "target": "G69758TR", "source": "G93707PO", "residue_affected": { "residue_id": "N72", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G93707PO", "source": "G55974RB", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G55974RB", "source": "G08187GM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69812OF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69905CP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G09670SR", "dp": 10 } ], "links": [ { "target": "G69905CP", "source": "G09670SR", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69912LP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G41720HN", "dp": 8 } ], "links": [ { "target": "G69912LP", "source": "G41720HN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G41720HN", "source": "G07483YN", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69957XS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G14127XU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G14127XU", "dp": 13 }, { "id": "G69957XS", "dp": 13 } ], "links": [ { "target": "G69957XS", "source": "G14127XU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14127XU", "source": "G91023GB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69960SA", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G69960SA] could be generated at this time" }, { "glytoucan_ac": "G69964CA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99770NO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G15103WJ", "dp": 12 }, { "id": "G99770NO", "dp": 13 }, { "id": "G69964CA", "dp": 13 } ], "links": [ { "target": "G69964CA", "source": "G99770NO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99770NO", "source": "G15103WJ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G15103WJ", "source": "G25520XG", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69976JD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40670DJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G69976JD", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G69982RY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 } ], "links": [ { "target": "G69982RY", "source": "G45560HM", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69985ZX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34905OT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 }, { "id": "G69985ZX", "dp": 11 } ], "links": [ { "target": "G69985ZX", "source": "G34905OT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G69987TD", "notes": [], "error": "No pathways for [G69987TD] could be generated at this time" }, { "glytoucan_ac": "G69996RR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53752TA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G69996RR", "dp": 11 } ], "links": [ { "target": "G69996RR", "source": "G53752TA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70052MF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40806JH]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G40806JH", "dp": 11 }, { "id": "G70052MF", "dp": 11 } ], "links": [ { "target": "G70052MF", "source": "G40806JH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40806JH", "source": "G11637WL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70059SD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G27919IH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G70059SD", "dp": 9 } ], "links": [ { "target": "G70059SD", "source": "G27919IH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70069EN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 }, { "id": "G05546WG", "dp": 9 } ], "links": [ { "target": "G70069EN", "source": "G05546WG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G05546WG", "source": "G69812OF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70072FZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60439QY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 }, { "id": "G37990ZT", "dp": 15 }, { "id": "G99891PR", "dp": 16 }, { "id": "G60439QY", "dp": 17 }, { "id": "G70072FZ", "dp": 17 } ], "links": [ { "target": "G70072FZ", "source": "G60439QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60439QY", "source": "G99891PR", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99891PR", "source": "G37990ZT", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70073SG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61751GZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G70073SG", "dp": 6 } ], "links": [ { "target": "G70073SG", "source": "G61751GZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G70076VV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G63333DU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G16529MG", "dp": 14 }, { "id": "G63333DU", "dp": 15 }, { "id": "G70076VV", "dp": 15 } ], "links": [ { "target": "G70076VV", "source": "G63333DU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63333DU", "source": "G16529MG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G16529MG", "source": "G56549DH", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70081QS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G31670BC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G97093EP", "dp": 12 }, { "id": "G31670BC", "dp": 13 }, { "id": "G70081QS", "dp": 13 } ], "links": [ { "target": "G70081QS", "source": "G31670BC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31670BC", "source": "G97093EP", "residue_affected": { "residue_id": "N246", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G97093EP", "source": "G43433FA", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70081SZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41656NL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 }, { "id": "G41656NL", "dp": 15 }, { "id": "G70081SZ", "dp": 15 } ], "links": [ { "target": "G70081SZ", "source": "G41656NL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41656NL", "source": "G23616ZX", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70113QZ", "notes": [], "error": "No pathways for [G70113QZ] could be generated at this time" }, { "glytoucan_ac": "G70116BN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80319WU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 }, { "id": "G37990ZT", "dp": 15 }, { "id": "G99891PR", "dp": 16 }, { "id": "G80319WU", "dp": 17 }, { "id": "G70116BN", "dp": 17 } ], "links": [ { "target": "G70116BN", "source": "G80319WU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80319WU", "source": "G99891PR", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G99891PR", "source": "G37990ZT", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70163ZD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G93427DE", "dp": 12 } ], "links": [ { "target": "G70163ZD", "source": "G93427DE", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G93427DE", "source": "G29857RC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70192AL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G34972BB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G34972BB", "dp": 15 }, { "id": "G70192AL", "dp": 15 } ], "links": [ { "target": "G70192AL", "source": "G34972BB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34972BB", "source": "G91905FJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70194YY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85260RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 }, { "id": "G85260RY", "dp": 16 }, { "id": "G70194YY", "dp": 16 } ], "links": [ { "target": "G70194YY", "source": "G85260RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85260RY", "source": "G57955DP", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70236HL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G33241WC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G33241WC", "dp": 15 }, { "id": "G70236HL", "dp": 15 } ], "links": [ { "target": "G70236HL", "source": "G33241WC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G33241WC", "source": "G45720CA", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70246WA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G52428MJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G52428MJ", "dp": 10 }, { "id": "G70246WA", "dp": 10 } ], "links": [ { "target": "G70246WA", "source": "G52428MJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52428MJ", "source": "G42672MA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70301QJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 } ], "links": [ { "target": "G70301QJ", "source": "G48658PB", "residue_affected": { "residue_id": "N223", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70342DW", "notes": [ "reducing end mismatch [b-D-GlcNAc]", "homologous pathway end-point [G48109OV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G70342DW", "dp": 24 } ], "links": [] } , { "glytoucan_ac": "G70358QM", "notes": [], "error": "No pathways for [G70358QM] could be generated at this time" }, { "glytoucan_ac": "G70374BH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G27919IH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G70374BH", "dp": 9 } ], "links": [ { "target": "G70374BH", "source": "G27919IH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70374KJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 } ], "links": [ { "target": "G70374KJ", "source": "G88417ED", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70377VS", "notes": [], "error": "No pathways for [G70377VS] could be generated at this time" }, { "glytoucan_ac": "G70382WT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30460NZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 }, { "id": "G70382WT", "dp": 11 } ], "links": [ { "target": "G70382WT", "source": "G30460NZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70387YT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52956BX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G52956BX", "dp": 9 }, { "id": "G70387YT", "dp": 9 } ], "links": [ { "target": "G70387YT", "source": "G52956BX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52956BX", "source": "G12398HZ", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70410NP", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G70410NP] could be generated at this time" }, { "glytoucan_ac": "G70490JW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82811EP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82811EP", "dp": 13 }, { "id": "G70490JW", "dp": 13 } ], "links": [ { "target": "G70490JW", "source": "G82811EP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82811EP", "source": "G84376FR", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70494TJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G92848CF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G70494TJ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G70511VE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 } ], "links": [ { "target": "G70511VE", "source": "G53752TA", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70520DS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G90348RI", "dp": 12 } ], "links": [ { "target": "G70520DS", "source": "G90348RI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G90348RI", "source": "G11041DA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70548CP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75445NA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G70548CP", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G70583LH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G70583LH] could be generated at this time" }, { "glytoucan_ac": "G70586HR", "notes": [], "error": "No pathways for [G70586HR] could be generated at this time" }, { "glytoucan_ac": "G70593DF", "notes": [], "error": "No pathways for [G70593DF] could be generated at this time" }, { "glytoucan_ac": "G70594XD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G40358EZ", "dp": 11 } ], "links": [ { "target": "G70594XD", "source": "G40358EZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G40358EZ", "source": "G00176HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70617CF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84783XD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G44623TX", "dp": 12 }, { "id": "G84783XD", "dp": 13 }, { "id": "G70617CF", "dp": 13 } ], "links": [ { "target": "G70617CF", "source": "G84783XD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84783XD", "source": "G44623TX", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G44623TX", "source": "G79809MM", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70642RS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26182BM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G70642RS", "dp": 8 } ], "links": [ { "target": "G70642RS", "source": "G26182BM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70651XZ", "notes": [], "error": "No pathways for [G70651XZ] could be generated at this time" }, { "glytoucan_ac": "G70670FB", "notes": [], "error": "No pathways for [G70670FB] could be generated at this time" }, { "glytoucan_ac": "G70681VG", "notes": [], "error": "No pathways for [G70681VG] could be generated at this time" }, { "glytoucan_ac": "G70684QL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G70684QL] could be generated at this time" }, { "glytoucan_ac": "G70708LW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 } ], "links": [ { "target": "G70708LW", "source": "G74675FC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70736PI", "notes": [], "error": "No pathways for [G70736PI] could be generated at this time" }, { "glytoucan_ac": "G70800WO", "notes": [], "error": "No pathways for [G70800WO] could be generated at this time" }, { "glytoucan_ac": "G70812GK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G39029JR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G39029JR", "dp": 10 }, { "id": "G70812GK", "dp": 10 } ], "links": [ { "target": "G70812GK", "source": "G39029JR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39029JR", "source": "G93500PH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70819AR", "notes": [], "error": "No pathways for [G70819AR] could be generated at this time" }, { "glytoucan_ac": "G70830AN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G70830AN] could be generated at this time" }, { "glytoucan_ac": "G70851FQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90725ZC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G90725ZC", "dp": 9 }, { "id": "G70851FQ", "dp": 9 } ], "links": [ { "target": "G70851FQ", "source": "G90725ZC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90725ZC", "source": "G89993FE", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70859XP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16523AO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G70859XP", "dp": 9 } ], "links": [ { "target": "G70859XP", "source": "G16523AO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70868QU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G70881GL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81923ER]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G81923ER", "dp": 10 }, { "id": "G70881GL", "dp": 10 } ], "links": [ { "target": "G70881GL", "source": "G81923ER", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70927FR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89285HT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G70927FR", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G70945OS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 } ], "links": [ { "target": "G70945OS", "source": "G41331JX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G70947EQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54300AX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G70947EQ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G70958LU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16600BL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G70958LU", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G71013KY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 } ], "links": [ { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71063DT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42022OY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G71063DT", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G71069MN", "notes": [], "error": "No pathways for [G71069MN] could be generated at this time" }, { "glytoucan_ac": "G71076CH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G64324VB", "dp": 8 }, { "id": "G01010HW", "dp": 9 } ], "links": [ { "target": "G71076CH", "source": "G01010HW", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01010HW", "source": "G64324VB", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G64324VB", "source": "G59741XZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71094TJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19687OL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G71094TJ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G71102UV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G40289RO", "dp": 10 } ], "links": [ { "target": "G71102UV", "source": "G40289RO", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G40289RO", "source": "G20966TZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71105IW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G87377KZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G71105IW", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G71118NV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G71118NV] could be generated at this time" }, { "glytoucan_ac": "G71125UE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29449JO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 }, { "id": "G71125UE", "dp": 13 } ], "links": [ { "target": "G71125UE", "source": "G29449JO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71153ZE", "notes": [], "error": "No pathways for [G71153ZE] could be generated at this time" }, { "glytoucan_ac": "G71156OO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G71204PH", "notes": [], "error": "No pathways for [G71204PH] could be generated at this time" }, { "glytoucan_ac": "G71296WI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G63585HN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 }, { "id": "G71296WI", "dp": 11 } ], "links": [ { "target": "G71296WI", "source": "G63585HN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71320DE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29377XJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 }, { "id": "G29377XJ", "dp": 12 }, { "id": "G71320DE", "dp": 12 } ], "links": [ { "target": "G71320DE", "source": "G29377XJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29377XJ", "source": "G63585HN", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71323UV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G71332MU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G06635WE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G71332MU", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G71333BH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G71333BH", "source": "G18938DW", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71360BB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38395YJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G38395YJ", "dp": 14 }, { "id": "G71360BB", "dp": 14 } ], "links": [ { "target": "G71360BB", "source": "G38395YJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38395YJ", "source": "G00909PI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71397MM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G71397MM] could be generated at this time" }, { "glytoucan_ac": "G71407IE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G71407IE", "source": "G69411IG", "residue_affected": { "residue_id": "N224", "pubchem_name": "Fuc", "anomer": "b", "absolute": "D", "form_name": "Fucp", "full_name": "β-D-Fucp" }, "effect": "Adds β-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71442FU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 } ], "links": [ { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71451NN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71679MX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G71451NN", "dp": 11 } ], "links": [ { "target": "G71451NN", "source": "G71679MX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71470CO", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G71470CO", "source": "G08520NM", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71513XV", "notes": [], "error": "No pathways for [G71513XV] could be generated at this time" }, { "glytoucan_ac": "G71529OW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G04791YX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G71529OW", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G71602GO", "notes": [], "error": "No pathways for [G71602GO] could be generated at this time" }, { "glytoucan_ac": "G71606HZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25520XG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G71606HZ", "dp": 11 } ], "links": [ { "target": "G71606HZ", "source": "G25520XG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71662HP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G03445UI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 }, { "id": "G71662HP", "dp": 10 } ], "links": [ { "target": "G71662HP", "source": "G03445UI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71679MX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71690HK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 } ], "links": [ { "target": "G71690HK", "source": "G61207RZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71704AG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G42686NQ", "dp": 14 } ], "links": [ { "target": "G71704AG", "source": "G42686NQ", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G42686NQ", "source": "G19726AG", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71714EQ", "notes": [], "error": "No pathways for [G71714EQ] could be generated at this time" }, { "glytoucan_ac": "G71765ZO", "notes": [], "error": "No pathways for [G71765ZO] could be generated at this time" }, { "glytoucan_ac": "G71782CJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43694RQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G71782CJ", "dp": 10 } ], "links": [ { "target": "G71782CJ", "source": "G43694RQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71812IK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 } ], "links": [ { "target": "G71812IK", "source": "G80858MF", "residue_affected": { "residue_id": "N322", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71828FH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G71828FH] could be generated at this time" }, { "glytoucan_ac": "G71835BN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G71835BN", "source": "G36191CD", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71857KQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 } ], "links": [ { "target": "G71857KQ", "source": "G29434RB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71865NO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G11535IB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G11535IB", "dp": 9 }, { "id": "G71865NO", "dp": 9 } ], "links": [ { "target": "G71865NO", "source": "G11535IB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11535IB", "source": "G59471TH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71888DL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G80294GH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G71888DL", "dp": 13 } ], "links": [ { "target": "G71888DL", "source": "G80294GH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71906BW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G71906BW] could be generated at this time" }, { "glytoucan_ac": "G71914DZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G84376FR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G71914DZ", "dp": 12 } ], "links": [ { "target": "G71914DZ", "source": "G84376FR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71923IX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G66313YW", "dp": 13 } ], "links": [ { "target": "G71923IX", "source": "G66313YW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66313YW", "source": "G74645FT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G71957GO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G71957GO] could be generated at this time" }, { "glytoucan_ac": "G71972AT", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G71972AT] could be generated at this time" }, { "glytoucan_ac": "G71989MV", "notes": [], "error": "No pathways for [G71989MV] could be generated at this time" }, { "glytoucan_ac": "G72018SI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G72082VM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G72018SI", "dp": 10 } ], "links": [ { "target": "G72018SI", "source": "G72082VM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72060AW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G29112GC", "dp": 10 } ], "links": [ { "target": "G72060AW", "source": "G29112GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29112GC", "source": "G20030CU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72075FO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G58547FH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G72075FO", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G72079JG", "notes": [], "error": "No pathways for [G72079JG] could be generated at this time" }, { "glytoucan_ac": "G72082VM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 } ], "links": [ { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72085DL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26939ZY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G26939ZY", "dp": 8 }, { "id": "G72085DL", "dp": 8 } ], "links": [ { "target": "G72085DL", "source": "G26939ZY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26939ZY", "source": "G39213VZ", "residue_affected": { "residue_id": "N306", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72103RY", "notes": [], "error": "No pathways for [G72103RY] could be generated at this time" }, { "glytoucan_ac": "G72108VJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98140IX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G98140IX", "dp": 7 }, { "id": "G72108VJ", "dp": 7 } ], "links": [ { "target": "G72108VJ", "source": "G98140IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98140IX", "source": "G61751GZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72112RK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G72112RK] could be generated at this time" }, { "glytoucan_ac": "G72125QI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G94047VH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 }, { "id": "G94047VH", "dp": 11 }, { "id": "G72125QI", "dp": 11 } ], "links": [ { "target": "G72125QI", "source": "G94047VH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94047VH", "source": "G07995VK", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72128LZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G89877QI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G72128LZ", "dp": 14 } ], "links": [ { "target": "G72128LZ", "source": "G89877QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72131JM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94531EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G94531EZ", "dp": 18 }, { "id": "G72131JM", "dp": 18 } ], "links": [ { "target": "G72131JM", "source": "G94531EZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72221XM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G45187EI", "dp": 11 } ], "links": [ { "target": "G72221XM", "source": "G45187EI", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G45187EI", "source": "G08577ZR", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72233LJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G57671LP]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G72233LJ", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G72260GO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G04743RS", "dp": 11 } ], "links": [ { "target": "G72260GO", "source": "G04743RS", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G04743RS", "source": "G88417ED", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72272ID", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G76384QV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G98852TR", "dp": 16 }, { "id": "G76384QV", "dp": 17 }, { "id": "G72272ID", "dp": 17 } ], "links": [ { "target": "G72272ID", "source": "G76384QV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76384QV", "source": "G98852TR", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G98852TR", "source": "G28957FB", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72281FQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G97453GF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G72281FQ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G72317JJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G29130SY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G72317JJ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G72334XM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G32156DB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G80661IW", "dp": 10 }, { "id": "G32156DB", "dp": 11 }, { "id": "G72334XM", "dp": 11 } ], "links": [ { "target": "G72334XM", "source": "G32156DB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32156DB", "source": "G80661IW", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G80661IW", "source": "G46638GC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72353NN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41953RN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G72353NN", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G72356JA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25140TA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 }, { "id": "G72356JA", "dp": 11 } ], "links": [ { "target": "G72356JA", "source": "G25140TA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72356TB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G73817GH", "dp": 10 }, { "id": "G57601AP", "dp": 11 } ], "links": [ { "target": "G72356TB", "source": "G57601AP", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G57601AP", "source": "G73817GH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72356VO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72580QS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G72580QS", "dp": 14 }, { "id": "G72356VO", "dp": 14 } ], "links": [ { "target": "G72356VO", "source": "G72580QS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72580QS", "source": "G66282NU", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72369ZI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71690HK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G71690HK", "dp": 10 }, { "id": "G72369ZI", "dp": 10 } ], "links": [ { "target": "G72369ZI", "source": "G71690HK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71690HK", "source": "G61207RZ", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72406BE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32659RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G32659RY", "dp": 12 }, { "id": "G72406BE", "dp": 12 } ], "links": [ { "target": "G72406BE", "source": "G32659RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32659RY", "source": "G59877NF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72407WU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G72411HX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G72411HX] could be generated at this time" }, { "glytoucan_ac": "G72460OS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88948CY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G72460OS", "dp": 11 } ], "links": [ { "target": "G72460OS", "source": "G88948CY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72475NE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G30483FB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G72475NE", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G72533FB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G52663AD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G72533FB", "dp": 9 } ], "links": [ { "target": "G72533FB", "source": "G52663AD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72536JI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 } ], "links": [ { "target": "G72536JI", "source": "G81432SH", "residue_affected": { "residue_id": "N237", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72578SV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G17689DH", "dp": 12 } ], "links": [ { "target": "G72578SV", "source": "G17689DH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72580QS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 } ], "links": [ { "target": "G72580QS", "source": "G66282NU", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72587UU", "notes": [], "error": "No pathways for [G72587UU] could be generated at this time" }, { "glytoucan_ac": "G72601EC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G32305RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G72601EC", "dp": 10 } ], "links": [ { "target": "G72601EC", "source": "G32305RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72662IG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G80537QW", "dp": 14 } ], "links": [ { "target": "G72662IG", "source": "G80537QW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G80537QW", "source": "G93582HM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72687PY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G92918FJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G72687PY", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G72690KN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G11929SN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G11929SN", "dp": 14 }, { "id": "G72690KN", "dp": 14 } ], "links": [ { "target": "G72690KN", "source": "G11929SN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11929SN", "source": "G80294GH", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72698LT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G82861UH", "dp": 9 } ], "links": [ { "target": "G72698LT", "source": "G82861UH", "residue_affected": { "residue_id": "N32", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G82861UH", "source": "G59471TH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72718TT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 } ], "links": [ { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72758KY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G72758WN", "notes": [], "error": "No pathways for [G72758WN] could be generated at this time" }, { "glytoucan_ac": "G72771HB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G72771HB] could be generated at this time" }, { "glytoucan_ac": "G72821WX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G72821WX", "source": "G12398HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72851IY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66204OA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G66204OA", "dp": 8 }, { "id": "G72851IY", "dp": 8 } ], "links": [ { "target": "G72851IY", "source": "G66204OA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66204OA", "source": "G39089YD", "residue_affected": { "residue_id": "N477", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylf", "full_name": "β-D-Xylf" }, "effect": "Adds β-D-Xylf", "enzymes": [] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G72893LL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G14512NS", "dp": 9 } ], "links": [ { "target": "G72893LL", "source": "G14512NS", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G14512NS", "source": "G24420RT", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72905QH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10733HY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 }, { "id": "G72905QH", "dp": 12 } ], "links": [ { "target": "G72905QH", "source": "G10733HY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72919IM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G72919IM] could be generated at this time" }, { "glytoucan_ac": "G72952WX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66595IQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G72952WX", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G72954XC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56749GV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G56749GV", "dp": 12 }, { "id": "G72954XC", "dp": 12 } ], "links": [ { "target": "G72954XC", "source": "G56749GV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56749GV", "source": "G11041DA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G72974NP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 }, { "id": "G01354KL", "dp": 14 } ], "links": [ { "target": "G72974NP", "source": "G01354KL", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01354KL", "source": "G41611UP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73051OD", "notes": [], "error": "No pathways for [G73051OD] could be generated at this time" }, { "glytoucan_ac": "G73057DA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 } ], "links": [ { "target": "G73057DA", "source": "G34527RW", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73111YU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G56318NV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G75237SS", "dp": 16 }, { "id": "G56318NV", "dp": 17 }, { "id": "G73111YU", "dp": 17 } ], "links": [ { "target": "G73111YU", "source": "G56318NV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56318NV", "source": "G75237SS", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73135FO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G73135FO", "source": "G09782JM", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73161ZQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G40909AN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G73161ZQ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G73170HU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G78885XB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G73170HU", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G73178TM", "notes": [], "error": "No pathways for [G73178TM] could be generated at this time" }, { "glytoucan_ac": "G73211XU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 }, { "id": "G95919TI", "dp": 14 } ], "links": [ { "target": "G73211XU", "source": "G95919TI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95919TI", "source": "G30651IU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73234BV", "notes": [], "error": "No pathways for [G73234BV] could be generated at this time" }, { "glytoucan_ac": "G73271AZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72082VM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G73271AZ", "dp": 10 } ], "links": [ { "target": "G73271AZ", "source": "G72082VM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73293TU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G73302KW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G74645FT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G73302KW", "dp": 12 } ], "links": [ { "target": "G73302KW", "source": "G74645FT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73308YY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75185NU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G73308YY", "dp": 12 } ], "links": [ { "target": "G73308YY", "source": "G75185NU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73367DT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G44202NB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G72821WX", "dp": 9 }, { "id": "G44202NB", "dp": 10 }, { "id": "G73367DT", "dp": 10 } ], "links": [ { "target": "G73367DT", "source": "G44202NB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44202NB", "source": "G72821WX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72821WX", "source": "G12398HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73402RN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G06969ZX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 }, { "id": "G73402RN", "dp": 10 } ], "links": [ { "target": "G73402RN", "source": "G06969ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73418FX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G00743WU", "dp": 11 } ], "links": [ { "target": "G73418FX", "source": "G00743WU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73439VG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40909AN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G73439VG", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G73492AT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 } ], "links": [ { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73499UJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10385EY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G73499UJ", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G73517CY", "notes": [], "error": "No pathways for [G73517CY] could be generated at this time" }, { "glytoucan_ac": "G73520AV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G73520AV] could be generated at this time" }, { "glytoucan_ac": "G73539WK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G86005HP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 }, { "id": "G25097RR", "dp": 15 }, { "id": "G86005HP", "dp": 16 }, { "id": "G73539WK", "dp": 16 } ], "links": [ { "target": "G73539WK", "source": "G86005HP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86005HP", "source": "G25097RR", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73560HZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G73560HZ", "source": "G66937TJ", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73567NI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G23616ZX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 }, { "id": "G73567NI", "dp": 14 } ], "links": [ { "target": "G73567NI", "source": "G23616ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73574GH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 } ], "links": [ { "target": "G73574GH", "source": "G75185NU", "residue_affected": { "residue_id": "N441", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73614SN", "notes": [], "error": "No pathways for [G73614SN] could be generated at this time" }, { "glytoucan_ac": "G73663PS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93655SG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G73663PS", "dp": 22 } ], "links": [] } , { "glytoucan_ac": "G73683LQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25407RZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 }, { "id": "G25407RZ", "dp": 11 }, { "id": "G73683LQ", "dp": 11 } ], "links": [ { "target": "G73683LQ", "source": "G25407RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25407RZ", "source": "G65597BI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73759SD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G96963QG", "dp": 12 } ], "links": [ { "target": "G73759SD", "source": "G96963QG", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73763NQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G63065KG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G73763NQ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G73775WR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73817GH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G73817GH", "source": "G09782JM", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73825BL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17540HT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 }, { "id": "G17540HT", "dp": 12 }, { "id": "G73825BL", "dp": 12 } ], "links": [ { "target": "G73825BL", "source": "G17540HT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17540HT", "source": "G30460NZ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73836ED", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G18594ZT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G73836ED", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G73866ZM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84467IZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 }, { "id": "G73866ZM", "dp": 11 } ], "links": [ { "target": "G73866ZM", "source": "G84467IZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73869CT", "notes": [], "error": "No pathways for [G73869CT] could be generated at this time" }, { "glytoucan_ac": "G73907HE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G93204KY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G57943ZV", "dp": 11 }, { "id": "G93204KY", "dp": 12 }, { "id": "G73907HE", "dp": 12 } ], "links": [ { "target": "G73907HE", "source": "G93204KY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93204KY", "source": "G57943ZV", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57943ZV", "source": "G52934AK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G73915OF", "notes": [], "error": "No pathways for [G73915OF] could be generated at this time" }, { "glytoucan_ac": "G73946HM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G73977KO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G73977KO] could be generated at this time" }, { "glytoucan_ac": "G73994XG", "notes": [], "error": "No pathways for [G73994XG] could be generated at this time" }, { "glytoucan_ac": "G74004KO", "notes": [], "error": "No pathways for [G74004KO] could be generated at this time" }, { "glytoucan_ac": "G74012OU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G28550OD", "dp": 9 } ], "links": [ { "target": "G74012OU", "source": "G28550OD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G28550OD", "source": "G12398HZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74018VM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G17134VG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G74018VM", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G74026TS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G17689DH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G17689DH", "dp": 12 }, { "id": "G74026TS", "dp": 12 } ], "links": [ { "target": "G74026TS", "source": "G17689DH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74054RO", "notes": [], "error": "No pathways for [G74054RO] could be generated at this time" }, { "glytoucan_ac": "G74066YL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G04576KS]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G04576KS", "dp": 10 }, { "id": "G74066YL", "dp": 10 } ], "links": [ { "target": "G74066YL", "source": "G04576KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04576KS", "source": "G16828VN", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74074HU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G74074HU] could be generated at this time" }, { "glytoucan_ac": "G74090KZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G74090KZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74107UT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G74107UT", "source": "G78059CC", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74111MH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43677TG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G74111MH", "dp": 8 } ], "links": [ { "target": "G74111MH", "source": "G43677TG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74120DW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G74120DW] could be generated at this time" }, { "glytoucan_ac": "G74154RA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82050MN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 }, { "id": "G74154RA", "dp": 13 } ], "links": [ { "target": "G74154RA", "source": "G82050MN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74238CC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G74238CC] could be generated at this time" }, { "glytoucan_ac": "G74248TD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03275SD]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G03275SD", "dp": 10 }, { "id": "G74248TD", "dp": 10 } ], "links": [ { "target": "G74248TD", "source": "G03275SD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03275SD", "source": "G16828VN", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74264KM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G74264KM] could be generated at this time" }, { "glytoucan_ac": "G74286KY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G74286KY] could be generated at this time" }, { "glytoucan_ac": "G74290AC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65890UA]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G65890UA", "dp": 10 }, { "id": "G74290AC", "dp": 10 } ], "links": [ { "target": "G74290AC", "source": "G65890UA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65890UA", "source": "G16828VN", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74312RU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46406BL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G46406BL", "dp": 12 }, { "id": "G74312RU", "dp": 12 } ], "links": [ { "target": "G74312RU", "source": "G46406BL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46406BL", "source": "G11041DA", "residue_affected": { "residue_id": "N276", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74324QB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 } ], "links": [ { "target": "G74324QB", "source": "G60564DP", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74325TG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25520XG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G74325TG", "dp": 11 } ], "links": [ { "target": "G74325TG", "source": "G25520XG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74364UH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G74369SL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G72919IM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G74369SL", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G74388OG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97309BN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G74388OG", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G74438AB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 } ], "links": [ { "target": "G74438AB", "source": "G34905OT", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74459BD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98140IX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G98140IX", "dp": 7 }, { "id": "G74459BD", "dp": 7 } ], "links": [ { "target": "G74459BD", "source": "G98140IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98140IX", "source": "G61751GZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74465ET", "notes": [], "error": "No pathways for [G74465ET] could be generated at this time" }, { "glytoucan_ac": "G74497TS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G74497TS] could be generated at this time" }, { "glytoucan_ac": "G74498IP", "notes": [], "error": "No pathways for [G74498IP] could be generated at this time" }, { "glytoucan_ac": "G74541EU", "notes": [], "error": "No pathways for [G74541EU] could be generated at this time" }, { "glytoucan_ac": "G74571ZF", "notes": [], "error": "No pathways for [G74571ZF] could be generated at this time" }, { "glytoucan_ac": "G74574VX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 } ], "links": [ { "target": "G74574VX", "source": "G27123NH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74608QW", "notes": [], "error": "No pathways for [G74608QW] could be generated at this time" }, { "glytoucan_ac": "G74645FT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 } ], "links": [ { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74673OI", "notes": [], "error": "No pathways for [G74673OI] could be generated at this time" }, { "glytoucan_ac": "G74675FC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74683SL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G88461FF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G74683SL", "dp": 9 } ], "links": [ { "target": "G74683SL", "source": "G88461FF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74716XL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09150LP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G09150LP", "dp": 12 }, { "id": "G74716XL", "dp": 12 } ], "links": [ { "target": "G74716XL", "source": "G09150LP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09150LP", "source": "G88948CY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74807KC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G09150LP", "dp": 12 }, { "id": "G78097CL", "dp": 13 } ], "links": [ { "target": "G74807KC", "source": "G78097CL", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78097CL", "source": "G09150LP", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G09150LP", "source": "G88948CY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74837KH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G58667NI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G74837KH", "dp": 9 } ], "links": [ { "target": "G74837KH", "source": "G58667NI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74859XI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G74859XI] could be generated at this time" }, { "glytoucan_ac": "G74910NC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G73057DA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G73057DA", "dp": 9 }, { "id": "G74910NC", "dp": 9 } ], "links": [ { "target": "G74910NC", "source": "G73057DA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G73057DA", "source": "G34527RW", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74912VG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 }, { "id": "G97958KV", "dp": 11 }, { "id": "G05143WC", "dp": 12 } ], "links": [ { "target": "G74912VG", "source": "G05143WC", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G05143WC", "source": "G97958KV", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G97958KV", "source": "G06969ZX", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G74916CC", "notes": [], "error": "No pathways for [G74916CC] could be generated at this time" }, { "glytoucan_ac": "G74928QN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 } ], "links": [ { "target": "G74928QN", "source": "G29449JO", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75039HL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G75039HL", "source": "G52934AK", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75049FP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 } ], "links": [ { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75082OS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99074EO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 }, { "id": "G75082OS", "dp": 13 } ], "links": [ { "target": "G75082OS", "source": "G99074EO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75087EW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39595CR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G39595CR", "dp": 14 }, { "id": "G75087EW", "dp": 14 } ], "links": [ { "target": "G75087EW", "source": "G39595CR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39595CR", "source": "G80294GH", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75097MF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75097MF] could be generated at this time" }, { "glytoucan_ac": "G75107JX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75107JX] could be generated at this time" }, { "glytoucan_ac": "G75120WS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 } ], "links": [ { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75143LK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 } ], "links": [ { "target": "G75143LK", "source": "G71013KY", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75185NU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 } ], "links": [ { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75197HN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G47175EF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G47175EF", "dp": 11 }, { "id": "G75197HN", "dp": 11 } ], "links": [ { "target": "G75197HN", "source": "G47175EF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75236EF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G63889NK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G75236EF", "dp": 14 } ], "links": [ { "target": "G75236EF", "source": "G63889NK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75237SS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 } ], "links": [ { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75308SV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G88966ZO", "dp": 15 } ], "links": [ { "target": "G75308SV", "source": "G88966ZO", "residue_affected": { "residue_id": "N37", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88966ZO", "source": "G63889NK", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75311GD", "notes": [], "error": "No pathways for [G75311GD] could be generated at this time" }, { "glytoucan_ac": "G75318VB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28298VW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 }, { "id": "G28298VW", "dp": 13 }, { "id": "G75318VB", "dp": 13 } ], "links": [ { "target": "G75318VB", "source": "G28298VW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28298VW", "source": "G48658PB", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75333EX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G29676WX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G06216UH", "dp": 10 }, { "id": "G49743VF", "dp": 11 }, { "id": "G29676WX", "dp": 12 }, { "id": "G75333EX", "dp": 12 } ], "links": [ { "target": "G75333EX", "source": "G29676WX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29676WX", "source": "G49743VF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G49743VF", "source": "G06216UH", "residue_affected": { "residue_id": "N470", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75345ZM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G73057DA", "dp": 9 } ], "links": [ { "target": "G75345ZM", "source": "G73057DA", "residue_affected": { "residue_id": "N204", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] }, { "target": "G73057DA", "source": "G34527RW", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75355YV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G61553DD", "dp": 9 } ], "links": [ { "target": "G75355YV", "source": "G61553DD", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G61553DD", "source": "G29011JC", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75359HS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G75359HS] could be generated at this time" }, { "glytoucan_ac": "G75367YS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G00176HZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G75367YS", "dp": 10 } ], "links": [ { "target": "G75367YS", "source": "G00176HZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75381NI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G30460NZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 }, { "id": "G75381NI", "dp": 11 } ], "links": [ { "target": "G75381NI", "source": "G30460NZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75398ZA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75398ZA] could be generated at this time" }, { "glytoucan_ac": "G75412QZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G75412QZ", "source": "G18938DW", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75445NA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75445NA] could be generated at this time" }, { "glytoucan_ac": "G75448JJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G06209KS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G06209KS", "dp": 8 }, { "id": "G75448JJ", "dp": 8 } ], "links": [ { "target": "G75448JJ", "source": "G06209KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06209KS", "source": "G69411IG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75475RA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G40428GO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G75475RA", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G75501QM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75501QM] could be generated at this time" }, { "glytoucan_ac": "G75502NG", "notes": [], "error": "No pathways for [G75502NG] could be generated at this time" }, { "glytoucan_ac": "G75554MB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G21788RU", "dp": 12 } ], "links": [ { "target": "G75554MB", "source": "G21788RU", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G21788RU", "source": "G25520XG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75564FK", "notes": [], "error": "No pathways for [G75564FK] could be generated at this time" }, { "glytoucan_ac": "G75584LU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29011JC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G75584LU", "dp": 8 } ], "links": [ { "target": "G75584LU", "source": "G29011JC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75595FQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 } ], "links": [ { "target": "G75595FQ", "source": "G71013KY", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75671DO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75671DO] could be generated at this time" }, { "glytoucan_ac": "G75701BM", "notes": [], "error": "No pathways for [G75701BM] could be generated at this time" }, { "glytoucan_ac": "G75704ZB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G91413ZX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G91413ZX", "dp": 15 }, { "id": "G75704ZB", "dp": 15 } ], "links": [ { "target": "G75704ZB", "source": "G91413ZX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75734VP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29676WX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G06216UH", "dp": 10 }, { "id": "G49743VF", "dp": 11 }, { "id": "G29676WX", "dp": 12 }, { "id": "G75734VP", "dp": 12 } ], "links": [ { "target": "G75734VP", "source": "G29676WX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29676WX", "source": "G49743VF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G49743VF", "source": "G06216UH", "residue_affected": { "residue_id": "N470", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G06216UH", "source": "G09482NW", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75757LG", "notes": [], "error": "No pathways for [G75757LG] could be generated at this time" }, { "glytoucan_ac": "G75764FQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G91511MZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G91511MZ", "dp": 12 }, { "id": "G75764FQ", "dp": 12 } ], "links": [ { "target": "G75764FQ", "source": "G91511MZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91511MZ", "source": "G11041DA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75811ON", "notes": [], "error": "No pathways for [G75811ON] could be generated at this time" }, { "glytoucan_ac": "G75824WJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60814ZB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 }, { "id": "G28106CM", "dp": 17 }, { "id": "G60814ZB", "dp": 18 }, { "id": "G75824WJ", "dp": 18 } ], "links": [ { "target": "G75824WJ", "source": "G60814ZB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60814ZB", "source": "G28106CM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75825ZR", "notes": [], "error": "No pathways for [G75825ZR] could be generated at this time" }, { "glytoucan_ac": "G75839SN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G45359RY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G75839SN", "dp": 12 } ], "links": [ { "target": "G75839SN", "source": "G45359RY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75850OP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G75850OP", "source": "G36191CD", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75853FN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75853FN] could be generated at this time" }, { "glytoucan_ac": "G75896PD", "notes": [ "pathway start-point [G08520NM]" ], "error": "DP error for glycan [G75896PD] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G75896QL", "notes": [], "error": "No pathways for [G75896QL] could be generated at this time" }, { "glytoucan_ac": "G75902JL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 } ], "links": [ { "target": "G75902JL", "source": "G93582HM", "residue_affected": { "residue_id": "N57", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75903TQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 } ], "links": [ { "target": "G75903TQ", "source": "G82252QI", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75937YG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38549YL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G21679ID", "dp": 11 }, { "id": "G38549YL", "dp": 12 }, { "id": "G75937YG", "dp": 12 } ], "links": [ { "target": "G75937YG", "source": "G38549YL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38549YL", "source": "G21679ID", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G21679ID", "source": "G52934AK", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G75972ZC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G75972ZC] could be generated at this time" }, { "glytoucan_ac": "G76073FF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G76073FF] could be generated at this time" }, { "glytoucan_ac": "G76075NA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 } ], "links": [ { "target": "G76075NA", "source": "G90870DG", "residue_affected": { "residue_id": "N62", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76084VW", "notes": [], "error": "No pathways for [G76084VW] could be generated at this time" }, { "glytoucan_ac": "G76127VR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G99465IE", "dp": 12 } ], "links": [ { "target": "G76127VR", "source": "G99465IE", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G99465IE", "source": "G06131VP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76136FD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G23626NI", "dp": 11 } ], "links": [ { "target": "G76136FD", "source": "G23626NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G23626NI", "source": "G85542KD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76190UX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G76190UX] could be generated at this time" }, { "glytoucan_ac": "G76195PM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G26264SQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G09921WG", "dp": 10 }, { "id": "G42028DN", "dp": 11 }, { "id": "G26264SQ", "dp": 12 }, { "id": "G76195PM", "dp": 12 } ], "links": [ { "target": "G76195PM", "source": "G26264SQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26264SQ", "source": "G42028DN", "residue_affected": { "residue_id": "N101", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G42028DN", "source": "G09921WG", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09921WG", "source": "G45262QY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76241TN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59471TH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G76241TN", "dp": 8 } ], "links": [ { "target": "G76241TN", "source": "G59471TH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76294TY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G76294TY] could be generated at this time" }, { "glytoucan_ac": "G76345AA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G76345AA", "source": "G12398HZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76384QV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G98852TR", "dp": 16 } ], "links": [ { "target": "G76384QV", "source": "G98852TR", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G98852TR", "source": "G28957FB", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76408CE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G83588YY", "dp": 15 }, { "id": "G54599TV", "dp": 16 } ], "links": [ { "target": "G76408CE", "source": "G54599TV", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G54599TV", "source": "G83588YY", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G83588YY", "source": "G11953VE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76422GC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 } ], "links": [ { "target": "G76422GC", "source": "G25140TA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76464YC", "notes": [], "error": "No pathways for [G76464YC] could be generated at this time" }, { "glytoucan_ac": "G76478FT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 } ], "links": [ { "target": "G76478FT", "source": "G78059CC", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76489QB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13659RH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G76489QB", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G76496FO", "notes": [], "error": "No pathways for [G76496FO] could be generated at this time" }, { "glytoucan_ac": "G76528ZS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G76528ZS", "source": "G52934AK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76554SR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G76554SR] could be generated at this time" }, { "glytoucan_ac": "G76582OA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G22354SF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G76582OA", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G76583MP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G93500PH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G76583MP", "dp": 9 } ], "links": [ { "target": "G76583MP", "source": "G93500PH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76603UJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 } ], "links": [ { "target": "G76603UJ", "source": "G09782JM", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76646HT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G76666KS", "notes": [], "error": "No pathways for [G76666KS] could be generated at this time" }, { "glytoucan_ac": "G76705RJ", "notes": [], "error": "No pathways for [G76705RJ] could be generated at this time" }, { "glytoucan_ac": "G76705YY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43873MM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G76705YY", "dp": 37 } ], "links": [] } , { "glytoucan_ac": "G76713YY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28747XN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G96921ZU", "dp": 12 }, { "id": "G28747XN", "dp": 13 }, { "id": "G76713YY", "dp": 13 } ], "links": [ { "target": "G76713YY", "source": "G28747XN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28747XN", "source": "G96921ZU", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96921ZU", "source": "G11041DA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76802ZU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 } ], "links": [ { "target": "G76802ZU", "source": "G12740VA", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76807JB", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G76807JB] could be generated at this time" }, { "glytoucan_ac": "G76842ZR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 } ], "links": [ { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76873LU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 } ], "links": [ { "target": "G76873LU", "source": "G62504BU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76882CO", "notes": [], "error": "No pathways for [G76882CO] could be generated at this time" }, { "glytoucan_ac": "G76907BP", "notes": [], "error": "No pathways for [G76907BP] could be generated at this time" }, { "glytoucan_ac": "G76924RW", "notes": [], "error": "No pathways for [G76924RW] could be generated at this time" }, { "glytoucan_ac": "G76931AL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23782KP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G76931AL", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G76945TE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80294GH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G80294GH", "dp": 13 }, { "id": "G76945TE", "dp": 13 } ], "links": [ { "target": "G76945TE", "source": "G80294GH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76956DJ", "notes": [], "error": "No pathways for [G76956DJ] could be generated at this time" }, { "glytoucan_ac": "G76983CM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G71812IK", "dp": 9 } ], "links": [ { "target": "G76983CM", "source": "G71812IK", "residue_affected": { "residue_id": "N223", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G71812IK", "source": "G80858MF", "residue_affected": { "residue_id": "N322", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G76986IU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G77025HC", "notes": [], "error": "No pathways for [G77025HC] could be generated at this time" }, { "glytoucan_ac": "G77058YR", "notes": [], "error": "No pathways for [G77058YR] could be generated at this time" }, { "glytoucan_ac": "G77097TR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G84874EV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 }, { "id": "G84874EV", "dp": 11 }, { "id": "G77097TR", "dp": 11 } ], "links": [ { "target": "G77097TR", "source": "G84874EV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84874EV", "source": "G99270AV", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77147RP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G60814ZB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 }, { "id": "G28106CM", "dp": 17 }, { "id": "G60814ZB", "dp": 18 }, { "id": "G77147RP", "dp": 18 } ], "links": [ { "target": "G77147RP", "source": "G60814ZB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60814ZB", "source": "G28106CM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77174TF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G82639GQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G77174TF", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G77207RR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99533GU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 }, { "id": "G28106CM", "dp": 17 }, { "id": "G99533GU", "dp": 18 }, { "id": "G77207RR", "dp": 18 } ], "links": [ { "target": "G77207RR", "source": "G99533GU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99533GU", "source": "G28106CM", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77244ZA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G31991IV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G77244ZA", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G77252PU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 } ], "links": [ { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77291EZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G77291EZ] could be generated at this time" }, { "glytoucan_ac": "G77384FE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G91337ZP", "dp": 10 } ], "links": [ { "target": "G77384FE", "source": "G91337ZP", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91337ZP", "source": "G58667NI", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77396HT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G58403SV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 }, { "id": "G58403SV", "dp": 11 }, { "id": "G77396HT", "dp": 11 } ], "links": [ { "target": "G77396HT", "source": "G58403SV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G58403SV", "source": "G99270AV", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77466MH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 } ], "links": [ { "target": "G77466MH", "source": "G89993FE", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77467SI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42097JO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 }, { "id": "G42097JO", "dp": 14 }, { "id": "G77467SI", "dp": 14 } ], "links": [ { "target": "G77467SI", "source": "G42097JO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G42097JO", "source": "G85085MS", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77475MM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G77475MM] could be generated at this time" }, { "glytoucan_ac": "G77479VH", "notes": [], "error": "No pathways for [G77479VH] could be generated at this time" }, { "glytoucan_ac": "G77485UZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G77485UZ] could be generated at this time" }, { "glytoucan_ac": "G77498XG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G77521TX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 } ], "links": [ { "target": "G77521TX", "source": "G78155FK", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77537OB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 } ], "links": [ { "target": "G77537OB", "source": "G03445UI", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77562VR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G77562VR] could be generated at this time" }, { "glytoucan_ac": "G77576VI", "notes": [ "reducing end mismatch [o-D-GlcNAc]", "homologous pathway end-point [G75185NU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G77576VI", "dp": 12 } ], "links": [ { "target": "G77576VI", "source": "G75185NU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77608VQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G33862NZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G77608VQ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G77638EE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G56147VV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 }, { "id": "G56147VV", "dp": 15 }, { "id": "G77638EE", "dp": 15 } ], "links": [ { "target": "G77638EE", "source": "G56147VV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56147VV", "source": "G17168RO", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77639OD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77646FX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69170UT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 }, { "id": "G69170UT", "dp": 14 }, { "id": "G77646FX", "dp": 14 } ], "links": [ { "target": "G77646FX", "source": "G69170UT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69170UT", "source": "G82050MN", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77670FL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82420SH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G82420SH", "dp": 10 }, { "id": "G77670FL", "dp": 10 } ], "links": [ { "target": "G77670FL", "source": "G82420SH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82420SH", "source": "G45262QY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77687SU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G77812KJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G77687SU", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G77712UR", "notes": [], "error": "No pathways for [G77712UR] could be generated at this time" }, { "glytoucan_ac": "G77748PL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G19444JC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G45720CA", "dp": 14 }, { "id": "G19444JC", "dp": 15 }, { "id": "G77748PL", "dp": 15 } ], "links": [ { "target": "G77748PL", "source": "G19444JC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19444JC", "source": "G45720CA", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45720CA", "source": "G19726AG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77755RE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G77755RE] could be generated at this time" }, { "glytoucan_ac": "G77791EJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39439UR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G39439UR", "dp": 9 }, { "id": "G77791EJ", "dp": 9 } ], "links": [ { "target": "G77791EJ", "source": "G39439UR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39439UR", "source": "G10209QU", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77812KJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G77812KJ] could be generated at this time" }, { "glytoucan_ac": "G77861QN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G77889NO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G85180ML]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G85180ML", "dp": 10 }, { "id": "G77889NO", "dp": 10 } ], "links": [ { "target": "G77889NO", "source": "G85180ML", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85180ML", "source": "G96063MG", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77915NM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47007PV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G77915NM", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G77922WZ", "notes": [], "error": "No pathways for [G77922WZ] could be generated at this time" }, { "glytoucan_ac": "G77939BF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G24748QU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G77939BF", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G77969OS", "notes": [], "error": "No pathways for [G77969OS] could be generated at this time" }, { "glytoucan_ac": "G77974XY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G77974XY", "source": "G20030CU", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G77977RG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G78000JX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06290ZS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G32611KT", "dp": 8 }, { "id": "G06290ZS", "dp": 9 }, { "id": "G78000JX", "dp": 9 } ], "links": [ { "target": "G78000JX", "source": "G06290ZS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06290ZS", "source": "G32611KT", "residue_affected": { "residue_id": "N32", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32611KT", "source": "G39213VZ", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78003VE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G37022BP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 }, { "id": "G37022BP", "dp": 12 }, { "id": "G78003VE", "dp": 12 } ], "links": [ { "target": "G78003VE", "source": "G37022BP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37022BP", "source": "G30460NZ", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78011JO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G78011JO] could be generated at this time" }, { "glytoucan_ac": "G78030KJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 } ], "links": [ { "target": "G78030KJ", "source": "G53812BX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78059CC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78097CL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G09150LP", "dp": 12 } ], "links": [ { "target": "G78097CL", "source": "G09150LP", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G09150LP", "source": "G88948CY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78126EU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G57675TR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G78126EU", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G78155FK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 } ], "links": [ { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78161IO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G17168RO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G39813YP", "dp": 13 }, { "id": "G17168RO", "dp": 14 }, { "id": "G78161IO", "dp": 14 } ], "links": [ { "target": "G78161IO", "source": "G17168RO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17168RO", "source": "G39813YP", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G39813YP", "source": "G03951JJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78173WX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 } ], "links": [ { "target": "G78173WX", "source": "G43694RQ", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78205VT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 }, { "id": "G31494OZ", "dp": 15 } ], "links": [ { "target": "G78205VT", "source": "G31494OZ", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G31494OZ", "source": "G60564DP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78255XL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G11535IB", "dp": 9 } ], "links": [ { "target": "G78255XL", "source": "G11535IB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11535IB", "source": "G59471TH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78276SQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G78276SQ", "source": "G11041DA", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78279JR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G78280YO", "notes": [], "error": "No pathways for [G78280YO] could be generated at this time" }, { "glytoucan_ac": "G78304UB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G50278HE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G78304UB", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G78325SJ", "notes": [], "error": "No pathways for [G78325SJ] could be generated at this time" }, { "glytoucan_ac": "G78341DP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G08520NM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G78341DP", "dp": 8 } ], "links": [ { "target": "G78341DP", "source": "G08520NM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G78341OF", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G28231AL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 }, { "id": "G95404EQ", "dp": 17 }, { "id": "G31004HS", "dp": 18 }, { "id": "G28231AL", "dp": 19 }, { "id": "G78341OF", "dp": 19 } ], "links": [ { "target": "G78341OF", "source": "G28231AL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28231AL", "source": "G31004HS", "residue_affected": { "residue_id": "N362", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G31004HS", "source": "G95404EQ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78342SP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20956ZK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G78342SP", "dp": 8 } ], "links": [ { "target": "G78342SP", "source": "G20956ZK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78368CZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G98140IX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G98140IX", "dp": 7 }, { "id": "G78368CZ", "dp": 7 } ], "links": [ { "target": "G78368CZ", "source": "G98140IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98140IX", "source": "G61751GZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78370NE", "notes": [], "error": "No pathways for [G78370NE] could be generated at this time" }, { "glytoucan_ac": "G78391CU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G88537BJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 }, { "id": "G88537BJ", "dp": 15 }, { "id": "G78391CU", "dp": 15 } ], "links": [ { "target": "G78391CU", "source": "G88537BJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88537BJ", "source": "G23616ZX", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78434AN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40906DZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G40906DZ", "dp": 14 }, { "id": "G78434AN", "dp": 14 } ], "links": [ { "target": "G78434AN", "source": "G40906DZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40906DZ", "source": "G18938DW", "residue_affected": { "residue_id": "N43", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78503JC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 } ], "links": [ { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78509IY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77974XY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77974XY", "dp": 10 }, { "id": "G78509IY", "dp": 10 } ], "links": [ { "target": "G78509IY", "source": "G77974XY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77974XY", "source": "G20030CU", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78513KA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G61088TM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G61088TM", "dp": 12 }, { "id": "G78513KA", "dp": 12 } ], "links": [ { "target": "G78513KA", "source": "G61088TM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61088TM", "source": "G90870DG", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78513VM", "notes": [], "error": "No pathways for [G78513VM] could be generated at this time" }, { "glytoucan_ac": "G78519ZX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G63333DU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G16529MG", "dp": 14 }, { "id": "G63333DU", "dp": 15 }, { "id": "G78519ZX", "dp": 15 } ], "links": [ { "target": "G78519ZX", "source": "G63333DU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63333DU", "source": "G16529MG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G16529MG", "source": "G56549DH", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78555BT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G82540VC", "dp": 8 }, { "id": "G41278YY", "dp": 9 } ], "links": [ { "target": "G78555BT", "source": "G41278YY", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G41278YY", "source": "G82540VC", "residue_affected": { "residue_id": "N238", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G82540VC", "source": "G39213VZ", "residue_affected": { "residue_id": "N250", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78625LN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G52187WF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G02290KA", "dp": 10 }, { "id": "G52187WF", "dp": 11 }, { "id": "G78625LN", "dp": 11 } ], "links": [ { "target": "G78625LN", "source": "G52187WF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52187WF", "source": "G02290KA", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G02290KA", "source": "G20030CU", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78648QN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G78648QN] could be generated at this time" }, { "glytoucan_ac": "G78661LW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 } ], "links": [ { "target": "G78661LW", "source": "G32201IL", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78681QL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61207RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G78681QL", "dp": 9 } ], "links": [ { "target": "G78681QL", "source": "G61207RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78727VW", "notes": [], "error": "No pathways for [G78727VW] could be generated at this time" }, { "glytoucan_ac": "G78730ZV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G99533GU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 }, { "id": "G28106CM", "dp": 17 }, { "id": "G99533GU", "dp": 18 }, { "id": "G78730ZV", "dp": 18 } ], "links": [ { "target": "G78730ZV", "source": "G99533GU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99533GU", "source": "G28106CM", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78741RD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 } ], "links": [ { "target": "G78741RD", "source": "G64669AQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G78768UQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G78797VK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 } ], "links": [ { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78803YD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 } ], "links": [ { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78813BX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G69905CP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G09670SR", "dp": 10 }, { "id": "G69905CP", "dp": 11 }, { "id": "G78813BX", "dp": 11 } ], "links": [ { "target": "G78813BX", "source": "G69905CP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69905CP", "source": "G09670SR", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78841KJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 } ], "links": [ { "target": "G78841KJ", "source": "G69812OF", "residue_affected": { "residue_id": "N250", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78885XB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G78885XB] could be generated at this time" }, { "glytoucan_ac": "G78890OB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 } ], "links": [ { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78894EE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39601JQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G78894EE", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G78944YP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G38115KZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G71857KQ", "dp": 10 }, { "id": "G38115KZ", "dp": 11 }, { "id": "G78944YP", "dp": 11 } ], "links": [ { "target": "G78944YP", "source": "G38115KZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38115KZ", "source": "G71857KQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71857KQ", "source": "G29434RB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78956IC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G91413ZX", "dp": 15 } ], "links": [ { "target": "G78956IC", "source": "G91413ZX", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G78961ZT", "notes": [], "error": "No pathways for [G78961ZT] could be generated at this time" }, { "glytoucan_ac": "G78980OK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G78980OK] could be generated at this time" }, { "glytoucan_ac": "G79010UT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G79010UT] could be generated at this time" }, { "glytoucan_ac": "G79018NX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57504TA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G28723UT", "dp": 11 }, { "id": "G57504TA", "dp": 12 }, { "id": "G79018NX", "dp": 12 } ], "links": [ { "target": "G79018NX", "source": "G57504TA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57504TA", "source": "G28723UT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28723UT", "source": "G87073UP", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79037RU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25392ZR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G79037RU", "dp": 24 } ], "links": [] } , { "glytoucan_ac": "G79044TC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G64669AQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 }, { "id": "G79044TC", "dp": 8 } ], "links": [ { "target": "G79044TC", "source": "G64669AQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G79071YL", "notes": [], "error": "No pathways for [G79071YL] could be generated at this time" }, { "glytoucan_ac": "G79083TK", "notes": [], "error": "No pathways for [G79083TK] could be generated at this time" }, { "glytoucan_ac": "G79084MU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16679DU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G69086TY", "dp": 12 }, { "id": "G42400JK", "dp": 13 }, { "id": "G16679DU", "dp": 14 }, { "id": "G79084MU", "dp": 14 } ], "links": [ { "target": "G79084MU", "source": "G16679DU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16679DU", "source": "G42400JK", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G42400JK", "source": "G69086TY", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79088GV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 } ], "links": [ { "target": "G79088GV", "source": "G66282NU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79089IH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G64633BH", "dp": 9 } ], "links": [ { "target": "G79089IH", "source": "G64633BH", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G64633BH", "source": "G79348ZY", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79099UV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G79099UV] could be generated at this time" }, { "glytoucan_ac": "G79183WP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 } ], "links": [ { "target": "G79183WP", "source": "G48658PB", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79198BK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G79198BK", "source": "G10219AA", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79198HM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G47011KD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G92024SL", "dp": 7 }, { "id": "G34527RW", "dp": 8 }, { "id": "G47011KD", "dp": 9 }, { "id": "G79198HM", "dp": 9 } ], "links": [ { "target": "G79198HM", "source": "G47011KD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47011KD", "source": "G34527RW", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G34527RW", "source": "G92024SL", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79202GR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G66765ZA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G79202GR", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G79215ZS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32592IB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 }, { "id": "G32592IB", "dp": 15 }, { "id": "G79215ZS", "dp": 15 } ], "links": [ { "target": "G79215ZS", "source": "G32592IB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32592IB", "source": "G10228OD", "residue_affected": { "residue_id": "N39", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79249GP", "notes": [], "error": "No pathways for [G79249GP] could be generated at this time" }, { "glytoucan_ac": "G79302PB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G79302PB] could be generated at this time" }, { "glytoucan_ac": "G79344MI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G12061IK", "dp": 11 } ], "links": [ { "target": "G79344MI", "source": "G12061IK", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G12061IK", "source": "G00176HZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79345TW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G79348ZY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 } ], "links": [ { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79349EV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84712FF", "dp": 12 }, { "id": "G42941KJ", "dp": 13 } ], "links": [ { "target": "G79349EV", "source": "G42941KJ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G42941KJ", "source": "G84712FF", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84712FF", "source": "G29857RC", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79351ZW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53396PX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 }, { "id": "G53396PX", "dp": 14 }, { "id": "G79351ZW", "dp": 14 } ], "links": [ { "target": "G79351ZW", "source": "G53396PX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53396PX", "source": "G82050MN", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79368CP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G46185ND]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G46185ND", "dp": 12 }, { "id": "G79368CP", "dp": 12 } ], "links": [ { "target": "G79368CP", "source": "G46185ND", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46185ND", "source": "G53752TA", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79369FE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G79370VG", "notes": [], "error": "No pathways for [G79370VG] could be generated at this time" }, { "glytoucan_ac": "G79394LC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G97765TT", "dp": 12 } ], "links": [ { "target": "G79394LC", "source": "G97765TT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G97765TT", "source": "G18219CJ", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79404OF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G79412GP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 } ], "links": [ { "target": "G79412GP", "source": "G35310KA", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79446WY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G91365ZQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G79446WY", "dp": 10 } ], "links": [ { "target": "G79446WY", "source": "G91365ZQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79457WN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G79457WN", "source": "G00176HZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79477YQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G65890UA]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G65890UA", "dp": 10 }, { "id": "G79477YQ", "dp": 10 } ], "links": [ { "target": "G79477YQ", "source": "G65890UA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65890UA", "source": "G16828VN", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79499QH", "notes": [], "error": "No pathways for [G79499QH] could be generated at this time" }, { "glytoucan_ac": "G79508WH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42175IR]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G79508WH", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G79518SC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G64077VW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G79518SC", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G79520GQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00320ZP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G79520GQ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G79523YN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G52333AW", "dp": 9 } ], "links": [ { "target": "G79523YN", "source": "G52333AW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G52333AW", "source": "G29492IF", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79546WW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G79556AB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 } ], "links": [ { "target": "G79556AB", "source": "G82252QI", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79565XA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G19469VZ", "dp": 18 } ], "links": [ { "target": "G79565XA", "source": "G19469VZ", "residue_affected": { "residue_id": "N108", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G19469VZ", "source": "G92574YO", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79578JB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79588PU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G14905MK", "dp": 10 } ], "links": [ { "target": "G79588PU", "source": "G14905MK", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G14905MK", "source": "G61207RZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79609RF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 } ], "links": [ { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79617NL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G29112GC", "dp": 10 } ], "links": [ { "target": "G79617NL", "source": "G29112GC", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G29112GC", "source": "G20030CU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79634CE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G97865QM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G79634CE", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G79643VQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90175OT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G37476QB", "dp": 8 }, { "id": "G90175OT", "dp": 9 }, { "id": "G79643VQ", "dp": 9 } ], "links": [ { "target": "G79643VQ", "source": "G90175OT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90175OT", "source": "G37476QB", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G37476QB", "source": "G59741XZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79662AK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G79702QE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98565KP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 }, { "id": "G98565KP", "dp": 15 }, { "id": "G79702QE", "dp": 15 } ], "links": [ { "target": "G79702QE", "source": "G98565KP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98565KP", "source": "G53485VW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79713BZ", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G04576KS]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G04576KS", "dp": 10 }, { "id": "G79713BZ", "dp": 10 } ], "links": [ { "target": "G79713BZ", "source": "G04576KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04576KS", "source": "G16828VN", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79726HB", "notes": [], "error": "No pathways for [G79726HB] could be generated at this time" }, { "glytoucan_ac": "G79754SY", "notes": [], "error": "No pathways for [G79754SY] could be generated at this time" }, { "glytoucan_ac": "G79771YZ", "notes": [], "error": "No pathways for [G79771YZ] could be generated at this time" }, { "glytoucan_ac": "G79781PS", "notes": [], "error": "No pathways for [G79781PS] could be generated at this time" }, { "glytoucan_ac": "G79790LK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G29112GC", "dp": 10 }, { "id": "G72060AW", "dp": 11 }, { "id": "G06032HI", "dp": 12 } ], "links": [ { "target": "G79790LK", "source": "G06032HI", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G06032HI", "source": "G72060AW", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G72060AW", "source": "G29112GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29112GC", "source": "G20030CU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79803HS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 }, { "id": "G74438AB", "dp": 12 } ], "links": [ { "target": "G79803HS", "source": "G74438AB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G74438AB", "source": "G34905OT", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79804QG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G79804QG] could be generated at this time" }, { "glytoucan_ac": "G79809MM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 } ], "links": [ { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79810PX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G37166HP]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G37166HP", "dp": 11 }, { "id": "G79810PX", "dp": 11 } ], "links": [ { "target": "G79810PX", "source": "G37166HP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37166HP", "source": "G11637WL", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79815MA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G79852UE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G41981MA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G41981MA", "dp": 15 }, { "id": "G79852UE", "dp": 15 } ], "links": [ { "target": "G79852UE", "source": "G41981MA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41981MA", "source": "G38022PE", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79916NT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G65832JS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G79916NT", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G79924QN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G12699VT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G12699VT", "dp": 11 }, { "id": "G79924QN", "dp": 11 } ], "links": [ { "target": "G79924QN", "source": "G12699VT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12699VT", "source": "G78059CC", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79950YS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 } ], "links": [ { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G79996DQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G58403SV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 }, { "id": "G58403SV", "dp": 11 }, { "id": "G79996DQ", "dp": 11 } ], "links": [ { "target": "G79996DQ", "source": "G58403SV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G58403SV", "source": "G99270AV", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80019MD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G37476QB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G37476QB", "dp": 8 }, { "id": "G80019MD", "dp": 8 } ], "links": [ { "target": "G80019MD", "source": "G37476QB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37476QB", "source": "G59741XZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80047AR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G03260OU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80047AR", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G80085KS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G80085KS] could be generated at this time" }, { "glytoucan_ac": "G80098ET", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G38208CY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G61684ET", "dp": 12 }, { "id": "G38208CY", "dp": 13 }, { "id": "G80098ET", "dp": 13 } ], "links": [ { "target": "G80098ET", "source": "G38208CY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38208CY", "source": "G61684ET", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G61684ET", "source": "G25520XG", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80124PG", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G29449JO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 }, { "id": "G80124PG", "dp": 13 } ], "links": [ { "target": "G80124PG", "source": "G29449JO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80142NN", "notes": [], "error": "No pathways for [G80142NN] could be generated at this time" }, { "glytoucan_ac": "G80147LG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 } ], "links": [ { "target": "G80147LG", "source": "G27919IH", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80163ME", "notes": [], "error": "No pathways for [G80163ME] could be generated at this time" }, { "glytoucan_ac": "G80180SI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G68946DB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G76528ZS", "dp": 11 }, { "id": "G68946DB", "dp": 12 }, { "id": "G80180SI", "dp": 12 } ], "links": [ { "target": "G80180SI", "source": "G68946DB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G68946DB", "source": "G76528ZS", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G76528ZS", "source": "G52934AK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80200DN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56354PO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80200DN", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G80201UB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G36268TW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 }, { "id": "G36268TW", "dp": 12 }, { "id": "G80201UB", "dp": 12 } ], "links": [ { "target": "G80201UB", "source": "G36268TW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36268TW", "source": "G77252PU", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80202YF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G80211PE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G25406HP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80211PE", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G80264ZA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G80264ZA] could be generated at this time" }, { "glytoucan_ac": "G80268ZC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86095OE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G75237SS", "dp": 16 }, { "id": "G86095OE", "dp": 17 }, { "id": "G80268ZC", "dp": 17 } ], "links": [ { "target": "G80268ZC", "source": "G86095OE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86095OE", "source": "G75237SS", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80294GH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 } ], "links": [ { "target": "G80294GH", "source": "G86357DX", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80298HR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51768ZH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80298HR", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G80319WU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 }, { "id": "G37990ZT", "dp": 15 }, { "id": "G99891PR", "dp": 16 } ], "links": [ { "target": "G80319WU", "source": "G99891PR", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G99891PR", "source": "G37990ZT", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80343LW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G29857RC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G80343LW", "dp": 11 } ], "links": [ { "target": "G80343LW", "source": "G29857RC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80352NL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 } ], "links": [ { "target": "G80352NL", "source": "G66282NU", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80355WT", "notes": [], "error": "No pathways for [G80355WT] could be generated at this time" }, { "glytoucan_ac": "G80366RR", "notes": [], "error": "No pathways for [G80366RR] could be generated at this time" }, { "glytoucan_ac": "G80393PG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80415EJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G91199QX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80415EJ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G80439QE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G80443OV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G80474MG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G80510YA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00797ZX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80510YA", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G80513FH", "notes": [], "error": "No pathways for [G80513FH] could be generated at this time" }, { "glytoucan_ac": "G80537QW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 } ], "links": [ { "target": "G80537QW", "source": "G93582HM", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80552MJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G94531EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G94531EZ", "dp": 18 }, { "id": "G80552MJ", "dp": 18 } ], "links": [ { "target": "G80552MJ", "source": "G94531EZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80566CZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G99866WK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G38395YJ", "dp": 14 }, { "id": "G99866WK", "dp": 15 }, { "id": "G80566CZ", "dp": 15 } ], "links": [ { "target": "G80566CZ", "source": "G99866WK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99866WK", "source": "G38395YJ", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G38395YJ", "source": "G00909PI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80578OK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 } ], "links": [ { "target": "G80578OK", "source": "G85767HW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80583XN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74012OU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G28550OD", "dp": 9 }, { "id": "G74012OU", "dp": 10 }, { "id": "G80583XN", "dp": 10 } ], "links": [ { "target": "G80583XN", "source": "G74012OU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74012OU", "source": "G28550OD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G28550OD", "source": "G12398HZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80612BO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99808VS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80612BO", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G80637VS", "notes": [], "error": "No pathways for [G80637VS] could be generated at this time" }, { "glytoucan_ac": "G80647PR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G80647PR] could be generated at this time" }, { "glytoucan_ac": "G80650PW", "notes": [], "error": "No pathways for [G80650PW] could be generated at this time" }, { "glytoucan_ac": "G80652ZF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G80652ZF", "source": "G39213VZ", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80654ZK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G13282WA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80654ZK", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G80661IW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G80661IW", "source": "G46638GC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80664ZC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G70520DS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G90348RI", "dp": 12 }, { "id": "G70520DS", "dp": 13 }, { "id": "G80664ZC", "dp": 13 } ], "links": [ { "target": "G80664ZC", "source": "G70520DS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70520DS", "source": "G90348RI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G90348RI", "source": "G11041DA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80717KS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G80717KS] could be generated at this time" }, { "glytoucan_ac": "G80756MK", "notes": [], "error": "No pathways for [G80756MK] could be generated at this time" }, { "glytoucan_ac": "G80858MF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 } ], "links": [ { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80943NY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G80943NY] could be generated at this time" }, { "glytoucan_ac": "G80945SX", "notes": [], "error": "No pathways for [G80945SX] could be generated at this time" }, { "glytoucan_ac": "G80952QT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30293NE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G80952QT", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G80962OX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G80962OX", "source": "G66937TJ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G80966KZ", "notes": [], "error": "No pathways for [G80966KZ] could be generated at this time" }, { "glytoucan_ac": "G80986RU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 }, { "id": "G81432SH", "dp": 12 } ], "links": [ { "target": "G80986RU", "source": "G81432SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81085EP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 } ], "links": [ { "target": "G81085EP", "source": "G87073UP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81096RM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G81096RM] could be generated at this time" }, { "glytoucan_ac": "G81114MS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42731RJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G81114MS", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G81121OC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26949IX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 }, { "id": "G81121OC", "dp": 11 } ], "links": [ { "target": "G81121OC", "source": "G26949IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81128IY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G07410AW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 }, { "id": "G07410AW", "dp": 14 }, { "id": "G81128IY", "dp": 14 } ], "links": [ { "target": "G81128IY", "source": "G07410AW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07410AW", "source": "G37597FW", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81147VU", "notes": [], "error": "No pathways for [G81147VU] could be generated at this time" }, { "glytoucan_ac": "G81153QC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G68758PE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G81153QC", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G81201TR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G71333BH", "dp": 14 } ], "links": [ { "target": "G81201TR", "source": "G71333BH", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G71333BH", "source": "G18938DW", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81253FL", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10219AA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G81253FL", "dp": 8 } ], "links": [ { "target": "G81253FL", "source": "G10219AA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81294ZY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G08493GY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G81294ZY", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G81295TF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G81326IN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G81326IN] could be generated at this time" }, { "glytoucan_ac": "G81328FA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G81328FA] could be generated at this time" }, { "glytoucan_ac": "G81333SO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G48329CR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G81333SO", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G81356NS", "notes": [], "error": "No pathways for [G81356NS] could be generated at this time" }, { "glytoucan_ac": "G81358TE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G45264AM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G45264AM", "dp": 10 }, { "id": "G81358TE", "dp": 10 } ], "links": [ { "target": "G81358TE", "source": "G45264AM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45264AM", "source": "G88461FF", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81380NE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G39018CC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G25505UF", "dp": 14 }, { "id": "G39018CC", "dp": 15 }, { "id": "G81380NE", "dp": 15 } ], "links": [ { "target": "G81380NE", "source": "G39018CC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39018CC", "source": "G25505UF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81389EF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G81389EF", "source": "G46638GC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81392TU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 } ], "links": [ { "target": "G81392TU", "source": "G85085MS", "residue_affected": { "residue_id": "N246", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81397LO", "notes": [], "error": "No pathways for [G81397LO] could be generated at this time" }, { "glytoucan_ac": "G81422ZI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G11637WL]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 }, { "id": "G81422ZI", "dp": 10 } ], "links": [ { "target": "G81422ZI", "source": "G11637WL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81430ON", "notes": [], "error": "No pathways for [G81430ON] could be generated at this time" }, { "glytoucan_ac": "G81432SH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 }, { "id": "G71442FU", "dp": 11 } ], "links": [ { "target": "G81432SH", "source": "G71442FU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G71442FU", "source": "G21755KD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81436EU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30159WR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G81436EU", "dp": 9 } ], "links": [ { "target": "G81436EU", "source": "G30159WR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81505ER", "notes": [], "error": "No pathways for [G81505ER] could be generated at this time" }, { "glytoucan_ac": "G81528UX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 } ], "links": [ { "target": "G81528UX", "source": "G89993FE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81536GE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 }, { "id": "G19124KK", "dp": 12 } ], "links": [ { "target": "G81536GE", "source": "G19124KK", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G19124KK", "source": "G84467IZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81554CS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G08577ZR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G81554CS", "dp": 10 } ], "links": [ { "target": "G81554CS", "source": "G08577ZR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81561UL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80085KS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G81561UL", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G81575FZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G13322RS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G81575FZ", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G81601EB", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G76554SR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G81601EB", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G81604KV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G02582JY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G79348ZY", "dp": 8 }, { "id": "G30901GC", "dp": 9 }, { "id": "G02582JY", "dp": 10 }, { "id": "G81604KV", "dp": 10 } ], "links": [ { "target": "G81604KV", "source": "G02582JY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02582JY", "source": "G30901GC", "residue_affected": { "residue_id": "N73", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G30901GC", "source": "G79348ZY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79348ZY", "source": "G10182XZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81663ZI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 } ], "links": [ { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81711SM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G86753CK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G86753CK", "dp": 17 }, { "id": "G81711SM", "dp": 17 } ], "links": [ { "target": "G81711SM", "source": "G86753CK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86753CK", "source": "G02311IE", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81738MQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G81738MQ] could be generated at this time" }, { "glytoucan_ac": "G81873QA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11034PZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G81873QA", "dp": 12 } ], "links": [ { "target": "G81873QA", "source": "G11034PZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81874XM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G16529MG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G16529MG", "dp": 14 }, { "id": "G81874XM", "dp": 14 } ], "links": [ { "target": "G81874XM", "source": "G16529MG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16529MG", "source": "G56549DH", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81912AC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G70708LW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 }, { "id": "G70708LW", "dp": 12 }, { "id": "G81912AC", "dp": 12 } ], "links": [ { "target": "G81912AC", "source": "G70708LW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G70708LW", "source": "G74675FC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81915YU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24413UY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G78890OB", "dp": 10 }, { "id": "G24413UY", "dp": 11 }, { "id": "G81915YU", "dp": 11 } ], "links": [ { "target": "G81915YU", "source": "G24413UY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G24413UY", "source": "G78890OB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78890OB", "source": "G96063MG", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81923ER", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 } ], "links": [ { "target": "G81923ER", "source": "G16523AO", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81933FO", "notes": [], "error": "No pathways for [G81933FO] could be generated at this time" }, { "glytoucan_ac": "G81960EK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G14996IQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G14996IQ", "dp": 8 }, { "id": "G81960EK", "dp": 8 } ], "links": [ { "target": "G81960EK", "source": "G14996IQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14996IQ", "source": "G69411IG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G81980VO", "notes": [], "error": "No pathways for [G81980VO] could be generated at this time" }, { "glytoucan_ac": "G82011YF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82011YF] could be generated at this time" }, { "glytoucan_ac": "G82033VN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 } ], "links": [ { "target": "G82033VN", "source": "G20926BB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82036CW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82036CW] could be generated at this time" }, { "glytoucan_ac": "G82050MN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 } ], "links": [ { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82081LV", "notes": [], "error": "No pathways for [G82081LV] could be generated at this time" }, { "glytoucan_ac": "G82126PQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G82127HP", "notes": [], "error": "No pathways for [G82127HP] could be generated at this time" }, { "glytoucan_ac": "G82130LG", "notes": [], "error": "No pathways for [G82130LG] could be generated at this time" }, { "glytoucan_ac": "G82140BL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G08709JB", "dp": 13 } ], "links": [ { "target": "G82140BL", "source": "G08709JB", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G08709JB", "source": "G45359RY", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82168GG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82168GG] could be generated at this time" }, { "glytoucan_ac": "G82169SQ", "notes": [], "error": "No pathways for [G82169SQ] could be generated at this time" }, { "glytoucan_ac": "G82195FD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10540LB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G82195FD", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G82201IZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G40027VO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G82201IZ", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G82207VX", "notes": [], "error": "No pathways for [G82207VX] could be generated at this time" }, { "glytoucan_ac": "G82221BU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G82227EQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G26756VT", "dp": 11 }, { "id": "G14617QG", "dp": 12 } ], "links": [ { "target": "G82227EQ", "source": "G14617QG", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G14617QG", "source": "G26756VT", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26756VT", "source": "G08863NS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82233UN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G20966TZ]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G82233UN", "dp": 9 } ], "links": [ { "target": "G82233UN", "source": "G20966TZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82234NO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82234NO] could be generated at this time" }, { "glytoucan_ac": "G82252QI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 } ], "links": [ { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82258GN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11671GQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G82258GN", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G82261XI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G86928UZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 }, { "id": "G86928UZ", "dp": 11 }, { "id": "G82261XI", "dp": 11 } ], "links": [ { "target": "G82261XI", "source": "G86928UZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86928UZ", "source": "G85767HW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82312JY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 } ], "links": [ { "target": "G82312JY", "source": "G80858MF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82320NZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82320NZ] could be generated at this time" }, { "glytoucan_ac": "G82348BZ", "notes": [], "error": "No pathways for [G82348BZ] could be generated at this time" }, { "glytoucan_ac": "G82350PP", "notes": [], "error": "No pathways for [G82350PP] could be generated at this time" }, { "glytoucan_ac": "G82357WL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 } ], "links": [ { "target": "G82357WL", "source": "G28826SH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82393PY", "notes": [], "error": "No pathways for [G82393PY] could be generated at this time" }, { "glytoucan_ac": "G82405LP", "notes": [], "error": "No pathways for [G82405LP] could be generated at this time" }, { "glytoucan_ac": "G82410AF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82410AF] could be generated at this time" }, { "glytoucan_ac": "G82420SH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 } ], "links": [ { "target": "G82420SH", "source": "G45262QY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82458BB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G96063MG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G82458BB", "dp": 9 } ], "links": [ { "target": "G82458BB", "source": "G96063MG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82487CR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 } ], "links": [ { "target": "G82487CR", "source": "G08194HH", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82529OA", "notes": [], "error": "No pathways for [G82529OA] could be generated at this time" }, { "glytoucan_ac": "G82540VC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G82540VC", "source": "G39213VZ", "residue_affected": { "residue_id": "N250", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82572FN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98862GW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G98862GW", "dp": 13 }, { "id": "G82572FN", "dp": 13 } ], "links": [ { "target": "G82572FN", "source": "G98862GW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98862GW", "source": "G75049FP", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82579AX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G45209NR", "dp": 15 } ], "links": [ { "target": "G82579AX", "source": "G45209NR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G45209NR", "source": "G91905FJ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82639GQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82639GQ] could be generated at this time" }, { "glytoucan_ac": "G82664ZC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03445UI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 }, { "id": "G82664ZC", "dp": 10 } ], "links": [ { "target": "G82664ZC", "source": "G03445UI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82680EC", "notes": [], "error": "No pathways for [G82680EC] could be generated at this time" }, { "glytoucan_ac": "G82699NN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82699NN] could be generated at this time" }, { "glytoucan_ac": "G82719GT", "notes": [], "error": "No pathways for [G82719GT] could be generated at this time" }, { "glytoucan_ac": "G82724NW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G49515VE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G49515VE", "dp": 12 }, { "id": "G82724NW", "dp": 12 } ], "links": [ { "target": "G82724NW", "source": "G49515VE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49515VE", "source": "G29857RC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82728DG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 } ], "links": [ { "target": "G82728DG", "source": "G06131VP", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82730QA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89865CB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G82730QA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G82761BO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07699XI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 }, { "id": "G07699XI", "dp": 11 }, { "id": "G82761BO", "dp": 11 } ], "links": [ { "target": "G82761BO", "source": "G07699XI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07699XI", "source": "G78155FK", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82773SI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G31991IV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G82773SI", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G82779CI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82779CI] could be generated at this time" }, { "glytoucan_ac": "G82782PE", "notes": [], "error": "No pathways for [G82782PE] could be generated at this time" }, { "glytoucan_ac": "G82801WV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84163ZT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G82801WV", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G82811EP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 } ], "links": [ { "target": "G82811EP", "source": "G84376FR", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82829MF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90223GH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G90223GH", "dp": 9 }, { "id": "G82829MF", "dp": 9 } ], "links": [ { "target": "G82829MF", "source": "G90223GH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90223GH", "source": "G29011JC", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82841UV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G67549HD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G82841UV", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G82845MH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14782PJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G82845MH", "dp": 15 } ], "links": [ { "target": "G82845MH", "source": "G14782PJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82847HG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82847HG] could be generated at this time" }, { "glytoucan_ac": "G82853YO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82853YO] could be generated at this time" }, { "glytoucan_ac": "G82861UH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 } ], "links": [ { "target": "G82861UH", "source": "G59471TH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82864KM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17155VX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G82864KM", "dp": 16 } ], "links": [ { "target": "G82864KM", "source": "G17155VX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82868SO", "notes": [], "error": "No pathways for [G82868SO] could be generated at this time" }, { "glytoucan_ac": "G82894XV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82894XV] could be generated at this time" }, { "glytoucan_ac": "G82917RE", "notes": [], "error": "No pathways for [G82917RE] could be generated at this time" }, { "glytoucan_ac": "G82942ZJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G82942ZJ", "source": "G08520NM", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G82954PR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G82954PR] could be generated at this time" }, { "glytoucan_ac": "G82955EQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 } ], "links": [ { "target": "G82955EQ", "source": "G87073UP", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83006TR", "notes": [], "error": "No pathways for [G83006TR] could be generated at this time" }, { "glytoucan_ac": "G83022ZQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G46185ND]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G46185ND", "dp": 12 }, { "id": "G83022ZQ", "dp": 12 } ], "links": [ { "target": "G83022ZQ", "source": "G46185ND", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46185ND", "source": "G53752TA", "residue_affected": { "residue_id": "N487", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83062JW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G09482NW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G09482NW", "dp": 9 }, { "id": "G83062JW", "dp": 9 } ], "links": [ { "target": "G83062JW", "source": "G09482NW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09482NW", "source": "G67045LB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83101KA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G90564EX", "dp": 11 }, { "id": "G08949VK", "dp": 12 }, { "id": "G12450CJ", "dp": 13 }, { "id": "G65079ZY", "dp": 14 } ], "links": [ { "target": "G83101KA", "source": "G65079ZY", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G65079ZY", "source": "G12450CJ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12450CJ", "source": "G08949VK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G08949VK", "source": "G90564EX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90564EX", "source": "G28826SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83106XM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39018CC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G25505UF", "dp": 14 }, { "id": "G39018CC", "dp": 15 }, { "id": "G83106XM", "dp": 15 } ], "links": [ { "target": "G83106XM", "source": "G39018CC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39018CC", "source": "G25505UF", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G25505UF", "source": "G20926BB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83131MU", "notes": [], "error": "No pathways for [G83131MU] could be generated at this time" }, { "glytoucan_ac": "G83161QT", "notes": [], "error": "No pathways for [G83161QT] could be generated at this time" }, { "glytoucan_ac": "G83216FM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83216FM] could be generated at this time" }, { "glytoucan_ac": "G83269PQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G21459ST]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83269PQ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G83312UD", "notes": [], "error": "No pathways for [G83312UD] could be generated at this time" }, { "glytoucan_ac": "G83393GK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G53962WT]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G83393GK", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G83402YY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83402YY] could be generated at this time" }, { "glytoucan_ac": "G83417GO", "notes": [], "error": "No pathways for [G83417GO] could be generated at this time" }, { "glytoucan_ac": "G83423JP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54590FS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83423JP", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G83425EJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G64789SR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83425EJ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G83433HW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G95898GD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 }, { "id": "G83433HW", "dp": 13 } ], "links": [ { "target": "G83433HW", "source": "G95898GD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83442GS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G34508UC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83442GS", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G83455QZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51562OR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83455QZ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G83490LO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G46638GC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G83490LO", "dp": 9 } ], "links": [ { "target": "G83490LO", "source": "G46638GC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83499UD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G74574VX", "dp": 11 } ], "links": [ { "target": "G83499UD", "source": "G74574VX", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74574VX", "source": "G27123NH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83508KY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83508KY] could be generated at this time" }, { "glytoucan_ac": "G83540SE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40554DX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G40554DX", "dp": 14 }, { "id": "G83540SE", "dp": 14 } ], "links": [ { "target": "G83540SE", "source": "G40554DX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40554DX", "source": "G75120WS", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83541HL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83541HL] could be generated at this time" }, { "glytoucan_ac": "G83582BK", "notes": [], "error": "No pathways for [G83582BK] could be generated at this time" }, { "glytoucan_ac": "G83588YY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 } ], "links": [ { "target": "G83588YY", "source": "G11953VE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83594ZB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G11929CD", "dp": 10 }, { "id": "G26795PW", "dp": 11 } ], "links": [ { "target": "G83594ZB", "source": "G26795PW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G26795PW", "source": "G11929CD", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G11929CD", "source": "G09782JM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83600PQ", "notes": [], "error": "No pathways for [G83600PQ] could be generated at this time" }, { "glytoucan_ac": "G83635VI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83635VI] could be generated at this time" }, { "glytoucan_ac": "G83644CC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76136FD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G23626NI", "dp": 11 }, { "id": "G76136FD", "dp": 12 }, { "id": "G83644CC", "dp": 12 } ], "links": [ { "target": "G83644CC", "source": "G76136FD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76136FD", "source": "G23626NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G23626NI", "source": "G85542KD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83662TS", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G62326NX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83662TS", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G83666RE", "notes": [], "error": "No pathways for [G83666RE] could be generated at this time" }, { "glytoucan_ac": "G83689NL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G83697UR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G83717YJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 } ], "links": [ { "target": "G83717YJ", "source": "G10219AA", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83737UD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86357DX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G83737UD", "dp": 12 } ], "links": [ { "target": "G83737UD", "source": "G86357DX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83738AG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83738AG] could be generated at this time" }, { "glytoucan_ac": "G83845ZV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83845ZV] could be generated at this time" }, { "glytoucan_ac": "G83864PP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G07262RR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83864PP", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G83895FM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G83541HL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G83895FM", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G83926PC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G41611UP", "dp": 13 }, { "id": "G01354KL", "dp": 14 } ], "links": [ { "target": "G83926PC", "source": "G01354KL", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01354KL", "source": "G41611UP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G41611UP", "source": "G86357DX", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G83945MQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G83948CA", "notes": [], "error": "No pathways for [G83948CA] could be generated at this time" }, { "glytoucan_ac": "G83957LU", "notes": [], "error": "No pathways for [G83957LU] could be generated at this time" }, { "glytoucan_ac": "G83958MI", "notes": [], "error": "No pathways for [G83958MI] could be generated at this time" }, { "glytoucan_ac": "G83992YN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G83992YN] could be generated at this time" }, { "glytoucan_ac": "G84033EZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34483UH]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G84033EZ", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G84041GN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G36787EI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G84041GN", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G84052CD", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53812BX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G84052CD", "dp": 13 } ], "links": [ { "target": "G84052CD", "source": "G53812BX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84053BQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G80858MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G84053BQ", "dp": 8 } ], "links": [ { "target": "G84053BQ", "source": "G80858MF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84064AY", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G84064AY", "source": "G08520NM", "residue_affected": { "residue_id": "N365", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G84108IZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G65307KA", "dp": 12 } ], "links": [ { "target": "G84108IZ", "source": "G65307KA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G65307KA", "source": "G10691MJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84153KU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G37597FW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 }, { "id": "G84153KU", "dp": 13 } ], "links": [ { "target": "G84153KU", "source": "G37597FW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84163ZT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84163ZT] could be generated at this time" }, { "glytoucan_ac": "G84167AV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G44152CO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G66866LE", "dp": 10 }, { "id": "G44152CO", "dp": 11 }, { "id": "G84167AV", "dp": 11 } ], "links": [ { "target": "G84167AV", "source": "G44152CO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44152CO", "source": "G66866LE", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66866LE", "source": "G96063MG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84170WO", "notes": [], "error": "No pathways for [G84170WO] could be generated at this time" }, { "glytoucan_ac": "G84186YN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96674LJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 }, { "id": "G96674LJ", "dp": 18 }, { "id": "G84186YN", "dp": 18 } ], "links": [ { "target": "G84186YN", "source": "G96674LJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96674LJ", "source": "G50489VC", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84223RT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G62765SF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G84223RT", "dp": 14 } ], "links": [ { "target": "G84223RT", "source": "G62765SF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84228AV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26756VT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G26756VT", "dp": 11 }, { "id": "G84228AV", "dp": 11 } ], "links": [ { "target": "G84228AV", "source": "G26756VT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26756VT", "source": "G08863NS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84260SO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74574VX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G74574VX", "dp": 11 }, { "id": "G84260SO", "dp": 11 } ], "links": [ { "target": "G84260SO", "source": "G74574VX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74574VX", "source": "G27123NH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84287MH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G25835MT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G25835MT", "dp": 10 }, { "id": "G84287MH", "dp": 10 } ], "links": [ { "target": "G84287MH", "source": "G25835MT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84301XG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G51562OR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G84301XG", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G84316BO", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G49827WK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 }, { "id": "G49827WK", "dp": 11 }, { "id": "G84316BO", "dp": 11 } ], "links": [ { "target": "G84316BO", "source": "G49827WK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G49827WK", "source": "G09446VC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84329MX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10258MC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G25835MT", "dp": 10 }, { "id": "G10258MC", "dp": 11 }, { "id": "G84329MX", "dp": 11 } ], "links": [ { "target": "G84329MX", "source": "G10258MC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10258MC", "source": "G25835MT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84330VA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84330VA] could be generated at this time" }, { "glytoucan_ac": "G84347HP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84347HP] could be generated at this time" }, { "glytoucan_ac": "G84363RQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 } ], "links": [ { "target": "G84363RQ", "source": "G07995VK", "residue_affected": { "residue_id": "N237", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84368MT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G84376FR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84390MS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84390MS] could be generated at this time" }, { "glytoucan_ac": "G84396LL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G68937TM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G84396LL", "dp": 10 } ], "links": [ { "target": "G84396LL", "source": "G68937TM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84410MY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G91413ZX", "dp": 15 } ], "links": [ { "target": "G84410MY", "source": "G91413ZX", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84423SZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G93464IM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G84423SZ", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G84440YT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G52934AK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G84440YT", "dp": 10 } ], "links": [ { "target": "G84440YT", "source": "G52934AK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84456HG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G71013KY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G84456HG", "dp": 10 } ], "links": [ { "target": "G84456HG", "source": "G71013KY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84467IZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 } ], "links": [ { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84495HF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G88461FF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G84495HF", "dp": 9 } ], "links": [ { "target": "G84495HF", "source": "G88461FF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84504LI", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G95658PH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G84504LI", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G84523VQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 } ], "links": [ { "target": "G84523VQ", "source": "G06969ZX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84536BM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84536BM] could be generated at this time" }, { "glytoucan_ac": "G84542XB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43255OW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G48954CA", "dp": 9 }, { "id": "G43255OW", "dp": 10 }, { "id": "G84542XB", "dp": 10 } ], "links": [ { "target": "G84542XB", "source": "G43255OW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43255OW", "source": "G48954CA", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G48954CA", "source": "G12398HZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84558OA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G99074EO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 }, { "id": "G84558OA", "dp": 13 } ], "links": [ { "target": "G84558OA", "source": "G99074EO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84560PS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 } ], "links": [ { "target": "G84560PS", "source": "G63889NK", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84648AY", "notes": [], "error": "No pathways for [G84648AY] could be generated at this time" }, { "glytoucan_ac": "G84674JQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G54611ZT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G54611ZT", "dp": 11 }, { "id": "G84674JQ", "dp": 11 } ], "links": [ { "target": "G84674JQ", "source": "G54611ZT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84678BK", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G39213VZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G84678BK", "dp": 7 } ], "links": [ { "target": "G84678BK", "source": "G39213VZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84680HD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G84692YW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G27776PG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G27776PG", "dp": 9 }, { "id": "G84692YW", "dp": 9 } ], "links": [ { "target": "G84692YW", "source": "G27776PG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G27776PG", "source": "G20956ZK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84709FG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84709FG] could be generated at this time" }, { "glytoucan_ac": "G84712FF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G84712FF", "source": "G29857RC", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84712FX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41596PV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G84712FX", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G84718MC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G44202NB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G72821WX", "dp": 9 }, { "id": "G44202NB", "dp": 10 }, { "id": "G84718MC", "dp": 10 } ], "links": [ { "target": "G84718MC", "source": "G44202NB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44202NB", "source": "G72821WX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72821WX", "source": "G12398HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84753IL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G29797YX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 }, { "id": "G89181JW", "dp": 11 }, { "id": "G29797YX", "dp": 12 }, { "id": "G84753IL", "dp": 12 } ], "links": [ { "target": "G84753IL", "source": "G29797YX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G29797YX", "source": "G89181JW", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G89181JW", "source": "G03445UI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84764CL", "notes": [], "error": "No pathways for [G84764CL] could be generated at this time" }, { "glytoucan_ac": "G84775PY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84775PY] could be generated at this time" }, { "glytoucan_ac": "G84776VF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 } ], "links": [ { "target": "G84776VF", "source": "G99270AV", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84777MO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84777MO] could be generated at this time" }, { "glytoucan_ac": "G84778XH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84778XH] could be generated at this time" }, { "glytoucan_ac": "G84783XD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G44623TX", "dp": 12 } ], "links": [ { "target": "G84783XD", "source": "G44623TX", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G44623TX", "source": "G79809MM", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84852GW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G84852GW", "source": "G12398HZ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84874EV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 }, { "id": "G99270AV", "dp": 10 } ], "links": [ { "target": "G84874EV", "source": "G99270AV", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84879CH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G84879CH] could be generated at this time" }, { "glytoucan_ac": "G84881ST", "notes": [], "error": "No pathways for [G84881ST] could be generated at this time" }, { "glytoucan_ac": "G84887KU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G31604HF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G31604HF", "dp": 8 }, { "id": "G84887KU", "dp": 8 } ], "links": [ { "target": "G84887KU", "source": "G31604HF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31604HF", "source": "G07483YN", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84901UD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G01378OV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G71835BN", "dp": 10 }, { "id": "G01378OV", "dp": 11 }, { "id": "G84901UD", "dp": 11 } ], "links": [ { "target": "G84901UD", "source": "G01378OV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G01378OV", "source": "G71835BN", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G71835BN", "source": "G36191CD", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84908OR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85116XO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G36701GV", "dp": 12 }, { "id": "G85116XO", "dp": 13 }, { "id": "G84908OR", "dp": 13 } ], "links": [ { "target": "G84908OR", "source": "G85116XO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85116XO", "source": "G36701GV", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36701GV", "source": "G53752TA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84942UA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G84964KJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G84964KJ", "source": "G29857RC", "residue_affected": { "residue_id": "N130", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G84975AL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G00514XC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G84975AL", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G84975VY", "notes": [], "error": "No pathways for [G84975VY] could be generated at this time" }, { "glytoucan_ac": "G85041WE", "notes": [], "error": "No pathways for [G85041WE] could be generated at this time" }, { "glytoucan_ac": "G85046IS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 } ], "links": [ { "target": "G85046IS", "source": "G06969ZX", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85085MS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 } ], "links": [ { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85093QP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G85093QP] could be generated at this time" }, { "glytoucan_ac": "G85100QD", "notes": [], "error": "No pathways for [G85100QD] could be generated at this time" }, { "glytoucan_ac": "G85101OA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G97453GF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G85101OA", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G85106DS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G85106DS] could be generated at this time" }, { "glytoucan_ac": "G85116XO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G36701GV", "dp": 12 } ], "links": [ { "target": "G85116XO", "source": "G36701GV", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36701GV", "source": "G53752TA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85121UD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G35599NO]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G85121UD", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G85141ZP", "notes": [], "error": "No pathways for [G85141ZP] could be generated at this time" }, { "glytoucan_ac": "G85159UF", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G85180ML", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 } ], "links": [ { "target": "G85180ML", "source": "G96063MG", "residue_affected": { "residue_id": "N490", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85200FA", "notes": [], "error": "No pathways for [G85200FA] could be generated at this time" }, { "glytoucan_ac": "G85208SY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G85208SY] could be generated at this time" }, { "glytoucan_ac": "G85213FQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G85213FQ", "source": "G61751GZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G85226CQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G61203OK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G85226CQ", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G85238RP", "notes": [], "error": "No pathways for [G85238RP] could be generated at this time" }, { "glytoucan_ac": "G85250EQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G85260RY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 } ], "links": [ { "target": "G85260RY", "source": "G57955DP", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85304RG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G75412QZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G75412QZ", "dp": 14 }, { "id": "G85304RG", "dp": 14 } ], "links": [ { "target": "G85304RG", "source": "G75412QZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75412QZ", "source": "G18938DW", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85317AM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G43677TG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G85317AM", "dp": 8 } ], "links": [ { "target": "G85317AM", "source": "G43677TG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85319UV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G80661IW", "dp": 10 } ], "links": [ { "target": "G85319UV", "source": "G80661IW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G80661IW", "source": "G46638GC", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85422ZY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G75049FP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G85422ZY", "dp": 12 } ], "links": [ { "target": "G85422ZY", "source": "G75049FP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85458AY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G91337ZP", "dp": 10 }, { "id": "G77384FE", "dp": 11 } ], "links": [ { "target": "G85458AY", "source": "G77384FE", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G77384FE", "source": "G91337ZP", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G91337ZP", "source": "G58667NI", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85460ZG", "notes": [], "error": "No pathways for [G85460ZG] could be generated at this time" }, { "glytoucan_ac": "G85471HV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G85530IT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32977ZV]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G85530IT", "dp": 8 } ], "links": [] } , { "glytoucan_ac": "G85542KD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 } ], "links": [ { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85545IG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03260OU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G85545IG", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G85599NG", "notes": [], "error": "No pathways for [G85599NG] could be generated at this time" }, { "glytoucan_ac": "G85650LS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 } ], "links": [ { "target": "G85650LS", "source": "G28826SH", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85652EW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36157OV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G36157OV", "dp": 11 }, { "id": "G85652EW", "dp": 11 } ], "links": [ { "target": "G85652EW", "source": "G36157OV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36157OV", "source": "G91365ZQ", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85652RK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30627OI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G85652RK", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G85750HN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G74238CC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G85750HN", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G85755BV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G68080UR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G85755BV", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G85767HW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 } ], "links": [ { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85768QF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G85768QF] could be generated at this time" }, { "glytoucan_ac": "G85790MP", "notes": [], "error": "No pathways for [G85790MP] could be generated at this time" }, { "glytoucan_ac": "G85795PL", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G85795PL] could be generated at this time" }, { "glytoucan_ac": "G85843WY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G66937TJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G85843WY", "dp": 8 } ], "links": [ { "target": "G85843WY", "source": "G66937TJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G85885QD", "notes": [], "error": "No pathways for [G85885QD] could be generated at this time" }, { "glytoucan_ac": "G85891FA", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G85891FA] could be generated at this time" }, { "glytoucan_ac": "G85895SP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G85895SP", "source": "G61751GZ", "residue_affected": { "residue_id": "N306", "pubchem_name": "Glc", "anomer": "b", "absolute": "D", "form_name": "Glcp", "full_name": "β-D-Glcp" }, "effect": "Adds β-D-Glcp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G85900AY", "notes": [], "error": "No pathways for [G85900AY] could be generated at this time" }, { "glytoucan_ac": "G85953MG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25731WL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G85953MG", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G85974HF", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G78030KJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G78030KJ", "dp": 14 }, { "id": "G85974HF", "dp": 14 } ], "links": [ { "target": "G85974HF", "source": "G78030KJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78030KJ", "source": "G53812BX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86002PC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G86002PC", "source": "G69411IG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86005HP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 }, { "id": "G91147LL", "dp": 14 }, { "id": "G25097RR", "dp": 15 } ], "links": [ { "target": "G86005HP", "source": "G25097RR", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G25097RR", "source": "G91147LL", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86018QV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G74264KM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G86018QV", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G86053IC", "notes": [], "error": "No pathways for [G86053IC] could be generated at this time" }, { "glytoucan_ac": "G86083QZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G04185VX", "dp": 10 }, { "id": "G30569KZ", "dp": 11 } ], "links": [ { "target": "G86083QZ", "source": "G30569KZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G30569KZ", "source": "G04185VX", "residue_affected": { "residue_id": "N239", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G04185VX", "source": "G36191CD", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86095OE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G75237SS", "dp": 16 } ], "links": [ { "target": "G86095OE", "source": "G75237SS", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G75237SS", "source": "G28957FB", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86102AA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 } ], "links": [ { "target": "G86102AA", "source": "G85542KD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86102WJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G89993FE]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 }, { "id": "G86102WJ", "dp": 8 } ], "links": [ { "target": "G86102WJ", "source": "G89993FE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86118KP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G89285HT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G86118KP", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G86157UQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98559XP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G98559XP", "dp": 14 }, { "id": "G86157UQ", "dp": 14 } ], "links": [ { "target": "G86157UQ", "source": "G98559XP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98559XP", "source": "G18938DW", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86188FJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G02422RD", "dp": 9 } ], "links": [ { "target": "G86188FJ", "source": "G02422RD", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G02422RD", "source": "G10219AA", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86191DF", "notes": [], "error": "No pathways for [G86191DF] could be generated at this time" }, { "glytoucan_ac": "G86202BL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G78503JC", "dp": 12 } ], "links": [ { "target": "G86202BL", "source": "G78503JC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78503JC", "source": "G31010RQ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86270DU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G86270DU", "source": "G11041DA", "residue_affected": { "residue_id": "N473", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86294MW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G86298IX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G47175EF", "dp": 11 }, { "id": "G60215UL", "dp": 12 } ], "links": [ { "target": "G86298IX", "source": "G60215UL", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G60215UL", "source": "G47175EF", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86309VR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10182XZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G86309VR", "dp": 7 } ], "links": [ { "target": "G86309VR", "source": "G10182XZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86321OX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G86321OX] could be generated at this time" }, { "glytoucan_ac": "G86357DX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 } ], "links": [ { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86377KB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G90542MP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G86377KB", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G86377SM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G86377SM] could be generated at this time" }, { "glytoucan_ac": "G86385RC", "notes": [], "error": "No pathways for [G86385RC] could be generated at this time" }, { "glytoucan_ac": "G86386QT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69411IG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G86386QT", "dp": 7 } ], "links": [ { "target": "G86386QT", "source": "G69411IG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86414FL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G81085EP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G87073UP", "dp": 10 }, { "id": "G81085EP", "dp": 11 }, { "id": "G86414FL", "dp": 11 } ], "links": [ { "target": "G86414FL", "source": "G81085EP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G81085EP", "source": "G87073UP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86445KR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G86466QK", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G31004HS]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 }, { "id": "G95404EQ", "dp": 17 }, { "id": "G31004HS", "dp": 18 }, { "id": "G86466QK", "dp": 18 } ], "links": [ { "target": "G86466QK", "source": "G31004HS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31004HS", "source": "G95404EQ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86475BX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G86487TG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G62826CL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G62826CL", "dp": 9 }, { "id": "G86487TG", "dp": 9 } ], "links": [ { "target": "G86487TG", "source": "G62826CL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G62826CL", "source": "G80858MF", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86490WA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G17473NR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 }, { "id": "G17473NR", "dp": 13 }, { "id": "G86490WA", "dp": 13 } ], "links": [ { "target": "G86490WA", "source": "G17473NR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17473NR", "source": "G10733HY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86495BQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56340GX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G56340GX", "dp": 10 }, { "id": "G86495BQ", "dp": 10 } ], "links": [ { "target": "G86495BQ", "source": "G56340GX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56340GX", "source": "G27919IH", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86504RY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59361OW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G59361OW", "dp": 11 }, { "id": "G86504RY", "dp": 11 } ], "links": [ { "target": "G86504RY", "source": "G59361OW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59361OW", "source": "G44946WH", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86517XT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G85767HW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 }, { "id": "G86517XT", "dp": 10 } ], "links": [ { "target": "G86517XT", "source": "G85767HW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86522OD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52934AK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G86522OD", "dp": 10 } ], "links": [ { "target": "G86522OD", "source": "G52934AK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86555OF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G86555OF] could be generated at this time" }, { "glytoucan_ac": "G86582QF", "notes": [], "error": "No pathways for [G86582QF] could be generated at this time" }, { "glytoucan_ac": "G86598ZY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G86598ZY] could be generated at this time" }, { "glytoucan_ac": "G86601RH", "notes": [], "error": "No pathways for [G86601RH] could be generated at this time" }, { "glytoucan_ac": "G86606NT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G16523AO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G16523AO", "dp": 9 }, { "id": "G86606NT", "dp": 9 } ], "links": [ { "target": "G86606NT", "source": "G16523AO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16523AO", "source": "G10219AA", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86681BW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G13267ZY", "dp": 10 } ], "links": [ { "target": "G86681BW", "source": "G13267ZY", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G13267ZY", "source": "G46638GC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86681UT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G23295TF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G23295TF", "dp": 10 }, { "id": "G86681UT", "dp": 10 } ], "links": [ { "target": "G86681UT", "source": "G23295TF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23295TF", "source": "G27919IH", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86696LV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 } ], "links": [ { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86704VD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G86704VD] could be generated at this time" }, { "glytoucan_ac": "G86730KO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 } ], "links": [ { "target": "G86730KO", "source": "G48658PB", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86753CK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 } ], "links": [ { "target": "G86753CK", "source": "G02311IE", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86770JF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G86770JF] could be generated at this time" }, { "glytoucan_ac": "G86781KH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G74928QN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G29449JO", "dp": 13 }, { "id": "G74928QN", "dp": 14 }, { "id": "G86781KH", "dp": 14 } ], "links": [ { "target": "G86781KH", "source": "G74928QN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G74928QN", "source": "G29449JO", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G29449JO", "source": "G45359RY", "residue_affected": { "residue_id": "N51", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86782KC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26935KA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G86782KC", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G86789PZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G86884BW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 } ], "links": [ { "target": "G86884BW", "source": "G69812OF", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86912FM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03473UD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G86912FM", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G86928SV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 } ], "links": [ { "target": "G86928SV", "source": "G62504BU", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86928UZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 } ], "links": [ { "target": "G86928UZ", "source": "G85767HW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G86952JZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G82036CW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G86952JZ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G87018HM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G89255EP", "dp": 13 } ], "links": [ { "target": "G87018HM", "source": "G89255EP", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G89255EP", "source": "G75049FP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87073UP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G87073UP", "source": "G36191CD", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87106NZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G87107PF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G87535DG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 }, { "id": "G87535DG", "dp": 12 }, { "id": "G87107PF", "dp": 12 } ], "links": [ { "target": "G87107PF", "source": "G87535DG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G87535DG", "source": "G74675FC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87124HX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G30880RA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G87124HX", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G87134ZP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G87134ZP", "source": "G39213VZ", "residue_affected": { "residue_id": "N513", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87136DV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G52645LW", "dp": 13 } ], "links": [ { "target": "G87136DV", "source": "G52645LW", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G52645LW", "source": "G79578JB", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87138HL", "notes": [], "error": "No pathways for [G87138HL] could be generated at this time" }, { "glytoucan_ac": "G87178PF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32704TW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G32704TW", "dp": 9 }, { "id": "G87178PF", "dp": 9 } ], "links": [ { "target": "G87178PF", "source": "G32704TW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32704TW", "source": "G12398HZ", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87192TH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G87192TH] could be generated at this time" }, { "glytoucan_ac": "G87202LK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 }, { "id": "G42097JO", "dp": 14 }, { "id": "G28846QB", "dp": 15 } ], "links": [ { "target": "G87202LK", "source": "G28846QB", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28846QB", "source": "G42097JO", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G42097JO", "source": "G85085MS", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87217OF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G71857KQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G71857KQ", "dp": 10 }, { "id": "G87217OF", "dp": 10 } ], "links": [ { "target": "G87217OF", "source": "G71857KQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71857KQ", "source": "G29434RB", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87260SO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G87264NH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G53854XZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G87264NH", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G87273JO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G02311IE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G87273JO", "dp": 16 } ], "links": [ { "target": "G87273JO", "source": "G02311IE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87293AR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G59655SA", "dp": 12 } ], "links": [ { "target": "G87293AR", "source": "G59655SA", "residue_affected": { "residue_id": "N457", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G59655SA", "source": "G53752TA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87308QC", "notes": [], "error": "No pathways for [G87308QC] could be generated at this time" }, { "glytoucan_ac": "G87309GS", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G80393PG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G87309GS", "dp": 9 } ], "links": [ { "target": "G87309GS", "source": "G80393PG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87349YT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 } ], "links": [ { "target": "G87349YT", "source": "G75049FP", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87377GM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G47108UC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G47108UC", "dp": 9 }, { "id": "G87377GM", "dp": 9 } ], "links": [ { "target": "G87377GM", "source": "G47108UC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G47108UC", "source": "G80858MF", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87377KZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G87377KZ] could be generated at this time" }, { "glytoucan_ac": "G87407JY", "notes": [], "error": "No pathways for [G87407JY] could be generated at this time" }, { "glytoucan_ac": "G87457SB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G87457SB] could be generated at this time" }, { "glytoucan_ac": "G87504BP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G11910RR", "dp": 15 } ], "links": [ { "target": "G87504BP", "source": "G11910RR", "residue_affected": { "residue_id": "N294", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G11910RR", "source": "G89877QI", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87535DG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G74675FC", "dp": 11 } ], "links": [ { "target": "G87535DG", "source": "G74675FC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G74675FC", "source": "G78059CC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87645JA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82410AF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G87645JA", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G87656FV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10258MC]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G25835MT", "dp": 10 }, { "id": "G10258MC", "dp": 11 }, { "id": "G87656FV", "dp": 11 } ], "links": [ { "target": "G87656FV", "source": "G10258MC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10258MC", "source": "G25835MT", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25835MT", "source": "G96063MG", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87668ED", "notes": [], "error": "No pathways for [G87668ED] could be generated at this time" }, { "glytoucan_ac": "G87687NN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G14615WQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G87687NN", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G87690VK", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G25407RZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 }, { "id": "G25407RZ", "dp": 11 }, { "id": "G87690VK", "dp": 11 } ], "links": [ { "target": "G87690VK", "source": "G25407RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25407RZ", "source": "G65597BI", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87692UE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G03385XG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G03385XG", "dp": 13 }, { "id": "G87692UE", "dp": 13 } ], "links": [ { "target": "G87692UE", "source": "G03385XG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03385XG", "source": "G01669LU", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87695KR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80393PG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G87695KR", "dp": 9 } ], "links": [ { "target": "G87695KR", "source": "G80393PG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87706EO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G87773EB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G37476QB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G37476QB", "dp": 8 }, { "id": "G87773EB", "dp": 8 } ], "links": [ { "target": "G87773EB", "source": "G37476QB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37476QB", "source": "G59741XZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87777GG", "notes": [], "error": "No pathways for [G87777GG] could be generated at this time" }, { "glytoucan_ac": "G87784HD", "notes": [], "error": "No pathways for [G87784HD] could be generated at this time" }, { "glytoucan_ac": "G87807PF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G87807PF] could be generated at this time" }, { "glytoucan_ac": "G87854BA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G67942CH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G67942CH", "dp": 11 }, { "id": "G87854BA", "dp": 11 } ], "links": [ { "target": "G87854BA", "source": "G67942CH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G67942CH", "source": "G71013KY", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87908HE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G11010AN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G87908HE", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G87918MM", "notes": [], "error": "No pathways for [G87918MM] could be generated at this time" }, { "glytoucan_ac": "G87921DA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G86357DX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G87921DA", "dp": 12 } ], "links": [ { "target": "G87921DA", "source": "G86357DX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G87937HR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21788RU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G21788RU", "dp": 12 }, { "id": "G87937HR", "dp": 12 } ], "links": [ { "target": "G87937HR", "source": "G21788RU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21788RU", "source": "G25520XG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88038QS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G62880PC", "dp": 9 }, { "id": "G45686NF", "dp": 10 } ], "links": [ { "target": "G88038QS", "source": "G45686NF", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45686NF", "source": "G62880PC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62880PC", "source": "G59471TH", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88069QW", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G28826SH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 }, { "id": "G88069QW", "dp": 10 } ], "links": [ { "target": "G88069QW", "source": "G28826SH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88094DN", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G88094DN] could be generated at this time" }, { "glytoucan_ac": "G88122ZQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76384QV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G98852TR", "dp": 16 }, { "id": "G76384QV", "dp": 17 }, { "id": "G88122ZQ", "dp": 17 } ], "links": [ { "target": "G88122ZQ", "source": "G76384QV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76384QV", "source": "G98852TR", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G98852TR", "source": "G28957FB", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88127MB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G88127MB] could be generated at this time" }, { "glytoucan_ac": "G88185OE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G99603GB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 }, { "id": "G99603GB", "dp": 9 }, { "id": "G88185OE", "dp": 9 } ], "links": [ { "target": "G88185OE", "source": "G99603GB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99603GB", "source": "G64669AQ", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G88219FI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G90223GH", "dp": 9 } ], "links": [ { "target": "G88219FI", "source": "G90223GH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90223GH", "source": "G29011JC", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88227HW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G60439QY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 }, { "id": "G37990ZT", "dp": 15 }, { "id": "G99891PR", "dp": 16 }, { "id": "G60439QY", "dp": 17 }, { "id": "G88227HW", "dp": 17 } ], "links": [ { "target": "G88227HW", "source": "G60439QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60439QY", "source": "G99891PR", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99891PR", "source": "G37990ZT", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88235TO", "notes": [], "error": "No pathways for [G88235TO] could be generated at this time" }, { "glytoucan_ac": "G88242BL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07392QY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G07392QY", "dp": 11 }, { "id": "G88242BL", "dp": 11 } ], "links": [ { "target": "G88242BL", "source": "G07392QY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G07392QY", "source": "G78059CC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88310CR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G78956IC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 }, { "id": "G91413ZX", "dp": 15 }, { "id": "G78956IC", "dp": 16 }, { "id": "G88310CR", "dp": 16 } ], "links": [ { "target": "G88310CR", "source": "G78956IC", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78956IC", "source": "G91413ZX", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88310KZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G88310KZ] could be generated at this time" }, { "glytoucan_ac": "G88321DT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 } ], "links": [ { "target": "G88321DT", "source": "G53485VW", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88329BN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G08520NM]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G88329BN", "dp": 8 } ], "links": [ { "target": "G88329BN", "source": "G08520NM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] } ] } , { "glytoucan_ac": "G88334IC", "notes": [], "error": "No pathways for [G88334IC] could be generated at this time" }, { "glytoucan_ac": "G88380UG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G88380UG", "source": "G39213VZ", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88382QE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G88382QE", "source": "G18938DW", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88417ED", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 } ], "links": [ { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88421PE", "notes": [], "error": "No pathways for [G88421PE] could be generated at this time" }, { "glytoucan_ac": "G88426SE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G78155FK", "dp": 10 } ], "links": [ { "target": "G88426SE", "source": "G78155FK", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78155FK", "source": "G43299SD", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88435TS", "notes": [], "error": "No pathways for [G88435TS] could be generated at this time" }, { "glytoucan_ac": "G88461FF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 } ], "links": [ { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88468EP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G29706UC", "dp": 10 } ], "links": [ { "target": "G88468EP", "source": "G29706UC", "residue_affected": { "residue_id": "N484", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G29706UC", "source": "G58667NI", "residue_affected": { "residue_id": "N86", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88495BI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77252PU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 }, { "id": "G88495BI", "dp": 11 } ], "links": [ { "target": "G88495BI", "source": "G77252PU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88500SX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19124KK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 }, { "id": "G19124KK", "dp": 12 }, { "id": "G88500SX", "dp": 12 } ], "links": [ { "target": "G88500SX", "source": "G19124KK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G19124KK", "source": "G84467IZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88537BJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G75120WS", "dp": 13 }, { "id": "G23616ZX", "dp": 14 } ], "links": [ { "target": "G88537BJ", "source": "G23616ZX", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G23616ZX", "source": "G75120WS", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G75120WS", "source": "G84376FR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88561PH", "notes": [], "error": "No pathways for [G88561PH] could be generated at this time" }, { "glytoucan_ac": "G88582ZD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G88582ZD] could be generated at this time" }, { "glytoucan_ac": "G88605BA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36324QX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G88605BA", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G88707IJ", "notes": [], "error": "No pathways for [G88707IJ] could be generated at this time" }, { "glytoucan_ac": "G88711NV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 }, { "id": "G42097JO", "dp": 14 }, { "id": "G28846QB", "dp": 15 } ], "links": [ { "target": "G88711NV", "source": "G28846QB", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G28846QB", "source": "G42097JO", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G42097JO", "source": "G85085MS", "residue_affected": { "residue_id": "N245", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88727SH", "notes": [], "error": "No pathways for [G88727SH] could be generated at this time" }, { "glytoucan_ac": "G88734GE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86753CK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G86753CK", "dp": 17 }, { "id": "G88734GE", "dp": 17 } ], "links": [ { "target": "G88734GE", "source": "G86753CK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86753CK", "source": "G02311IE", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88749TS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50023BR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G88749TS", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G88757PX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G88784SV", "notes": [], "error": "No pathways for [G88784SV] could be generated at this time" }, { "glytoucan_ac": "G88800UV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G18938DW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G88800UV", "dp": 13 } ], "links": [ { "target": "G88800UV", "source": "G18938DW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88814KX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G61718TK", "dp": 11 } ], "links": [ { "target": "G88814KX", "source": "G61718TK", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G61718TK", "source": "G43694RQ", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88827CD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59942FB]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G56748EO", "dp": 10 }, { "id": "G59942FB", "dp": 11 }, { "id": "G88827CD", "dp": 11 } ], "links": [ { "target": "G88827CD", "source": "G59942FB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59942FB", "source": "G56748EO", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88864RV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G88864RV] could be generated at this time" }, { "glytoucan_ac": "G88876JQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G39213VZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G88876JQ", "dp": 7 } ], "links": [ { "target": "G88876JQ", "source": "G39213VZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88878CV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G88878CV] could be generated at this time" }, { "glytoucan_ac": "G88884NJ", "notes": [], "error": "No pathways for [G88884NJ] could be generated at this time" }, { "glytoucan_ac": "G88913VB", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 } ], "links": [ { "target": "G88913VB", "source": "G16828VN", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88928GI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G88928GI", "source": "G11041DA", "residue_affected": { "residue_id": "N55", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88948CY", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 } ], "links": [ { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88966ZO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 } ], "links": [ { "target": "G88966ZO", "source": "G63889NK", "residue_affected": { "residue_id": "N36", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "B3GNT2", "uniprot": "Q9NY97", "type": "GT", "species": "human" }, { "gene_name": "B3GNT4", "uniprot": "Q9C0J1", "type": "GT", "species": "human" }, { "gene_name": "B3GNT8", "uniprot": "Q7Z7M8", "type": "GT", "species": "human" }, { "gene_name": "B3gnt2", "uniprot": "Q9Z222", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt4", "uniprot": "Q1RLK6", "type": "GT", "species": "mouse" }, { "gene_name": "B3gnt8", "uniprot": "Q8R3I9", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G88998CC", "notes": [], "error": "No pathways for [G88998CC] could be generated at this time" }, { "glytoucan_ac": "G89036WC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G89036WC", "source": "G69411IG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89058RF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86555OF]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G89058RF", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G89099NM", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 } ], "links": [ { "target": "G89099NM", "source": "G20966TZ", "residue_affected": { "residue_id": "N23", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "ALG12", "uniprot": "Q9BV10", "type": "GT", "species": "human" }, { "gene_name": "Alg12", "uniprot": "Q8VDB2", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89117DH", "notes": [], "error": "No pathways for [G89117DH] could be generated at this time" }, { "glytoucan_ac": "G89143RS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G89143RS] could be generated at this time" }, { "glytoucan_ac": "G89153EV", "notes": [], "error": "No pathways for [G89153EV] could be generated at this time" }, { "glytoucan_ac": "G89168LM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 } ], "links": [ { "target": "G89168LM", "source": "G63889NK", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89181JW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G03445UI", "dp": 10 } ], "links": [ { "target": "G89181JW", "source": "G03445UI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G03445UI", "source": "G61207RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89206JP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G89206JP] could be generated at this time" }, { "glytoucan_ac": "G89253ZV", "notes": [], "error": "No pathways for [G89253ZV] could be generated at this time" }, { "glytoucan_ac": "G89255EP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 } ], "links": [ { "target": "G89255EP", "source": "G75049FP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89261EQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16774YZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 }, { "id": "G16774YZ", "dp": 18 }, { "id": "G89261EQ", "dp": 18 } ], "links": [ { "target": "G89261EQ", "source": "G16774YZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16774YZ", "source": "G86696LV", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89285HT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G89285HT] could be generated at this time" }, { "glytoucan_ac": "G89285QP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G85542KD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G89285QP", "dp": 10 } ], "links": [ { "target": "G89285QP", "source": "G85542KD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89290XU", "notes": [], "error": "No pathways for [G89290XU] could be generated at this time" }, { "glytoucan_ac": "G89323TE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G80943NY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G89323TE", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G89325VN", "notes": [], "error": "No pathways for [G89325VN] could be generated at this time" }, { "glytoucan_ac": "G89345GA", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G00662IB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G89345GA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G89353OJ", "notes": [], "error": "No pathways for [G89353OJ] could be generated at this time" }, { "glytoucan_ac": "G89362MU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G86928SV", "dp": 11 } ], "links": [ { "target": "G89362MU", "source": "G86928SV", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G86928SV", "source": "G62504BU", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89364NG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24748QU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G89364NG", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G89366NN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G89366NN] could be generated at this time" }, { "glytoucan_ac": "G89375LQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90698PW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G34175ZP", "dp": 10 }, { "id": "G90698PW", "dp": 11 }, { "id": "G89375LQ", "dp": 11 } ], "links": [ { "target": "G89375LQ", "source": "G90698PW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90698PW", "source": "G34175ZP", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G34175ZP", "source": "G01265XZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89498BT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82639GQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G89498BT", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G89532GI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32201IL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G89532GI", "dp": 10 } ], "links": [ { "target": "G89532GI", "source": "G32201IL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89561DW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G89561DW", "source": "G39213VZ", "residue_affected": { "residue_id": "N422", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89584RR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G45603BW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G45603BW", "dp": 14 }, { "id": "G89584RR", "dp": 14 } ], "links": [ { "target": "G89584RR", "source": "G45603BW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G45603BW", "source": "G56549DH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89615SV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G08242BT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 }, { "id": "G08242BT", "dp": 12 }, { "id": "G89615SV", "dp": 12 } ], "links": [ { "target": "G89615SV", "source": "G08242BT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08242BT", "source": "G26949IX", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89619KY", "notes": [], "error": "No pathways for [G89619KY] could be generated at this time" }, { "glytoucan_ac": "G89637WE", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G80858MF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G89637WE", "dp": 8 } ], "links": [ { "target": "G89637WE", "source": "G80858MF", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89654YT", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G79457WN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G79457WN", "dp": 11 }, { "id": "G89654YT", "dp": 11 } ], "links": [ { "target": "G89654YT", "source": "G79457WN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79457WN", "source": "G00176HZ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89663TB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G30159WR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G89663TB", "dp": 9 } ], "links": [ { "target": "G89663TB", "source": "G30159WR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89669IB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G56748EO]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G56748EO", "dp": 10 }, { "id": "G89669IB", "dp": 10 } ], "links": [ { "target": "G89669IB", "source": "G56748EO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89808TP", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G05260RH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G56591LC", "dp": 10 }, { "id": "G05260RH", "dp": 11 }, { "id": "G89808TP", "dp": 11 } ], "links": [ { "target": "G89808TP", "source": "G05260RH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G05260RH", "source": "G56591LC", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G56591LC", "source": "G36191CD", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89838LO", "notes": [], "error": "No pathways for [G89838LO] could be generated at this time" }, { "glytoucan_ac": "G89845CN", "notes": [], "error": "No pathways for [G89845CN] could be generated at this time" }, { "glytoucan_ac": "G89864BN", "notes": [], "error": "No pathways for [G89864BN] could be generated at this time" }, { "glytoucan_ac": "G89865CB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G89865CB] could be generated at this time" }, { "glytoucan_ac": "G89877QI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 } ], "links": [ { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89905SH", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G00536FZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G00536FZ", "dp": 12 }, { "id": "G89905SH", "dp": 12 } ], "links": [ { "target": "G89905SH", "source": "G00536FZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00536FZ", "source": "G71679MX", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89920YU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G89923TD", "notes": [], "error": "No pathways for [G89923TD] could be generated at this time" }, { "glytoucan_ac": "G89941FZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G00743WU", "dp": 11 } ], "links": [ { "target": "G89941FZ", "source": "G00743WU", "residue_affected": { "residue_id": "N70", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G89970IY", "notes": [], "error": "No pathways for [G89970IY] could be generated at this time" }, { "glytoucan_ac": "G89993FE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 } ], "links": [ { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90000WS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10614GM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G10614GM", "dp": 9 }, { "id": "G90000WS", "dp": 9 } ], "links": [ { "target": "G90000WS", "source": "G10614GM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10614GM", "source": "G10209QU", "residue_affected": { "residue_id": "N275", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90017UO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90028HY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75903TQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G90017UO", "dp": 10 }, { "id": "G82252QI", "dp": 11 }, { "id": "G75903TQ", "dp": 12 }, { "id": "G90028HY", "dp": 12 } ], "links": [ { "target": "G90028HY", "source": "G75903TQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75903TQ", "source": "G82252QI", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G82252QI", "source": "G90017UO", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90017UO", "source": "G58667NI", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90033AN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53098FA]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 }, { "id": "G53098FA", "dp": 14 }, { "id": "G90033AN", "dp": 14 } ], "links": [ { "target": "G90033AN", "source": "G53098FA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53098FA", "source": "G95898GD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90054TK", "notes": [], "error": "No pathways for [G90054TK] could be generated at this time" }, { "glytoucan_ac": "G90065BD", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G90065BD] could be generated at this time" }, { "glytoucan_ac": "G90099GV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G84467IZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G84467IZ", "dp": 11 }, { "id": "G90099GV", "dp": 11 } ], "links": [ { "target": "G90099GV", "source": "G84467IZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84467IZ", "source": "G91365ZQ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90111MD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G03895SR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 }, { "id": "G03895SR", "dp": 15 }, { "id": "G90111MD", "dp": 15 } ], "links": [ { "target": "G90111MD", "source": "G03895SR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03895SR", "source": "G16150CJ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90130AG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G90130AG] could be generated at this time" }, { "glytoucan_ac": "G90163GT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G69812OF", "dp": 8 }, { "id": "G05546WG", "dp": 9 } ], "links": [ { "target": "G90163GT", "source": "G05546WG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G05546WG", "source": "G69812OF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69812OF", "source": "G39213VZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90175OT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G37476QB", "dp": 8 } ], "links": [ { "target": "G90175OT", "source": "G37476QB", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G37476QB", "source": "G59741XZ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90204HK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G90223GH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G90223GH", "source": "G29011JC", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90244AZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 } ], "links": [ { "target": "G90244AZ", "source": "G29492IF", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90284FM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 } ], "links": [ { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90348RI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G90348RI", "source": "G11041DA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90363CW", "notes": [], "error": "No pathways for [G90363CW] could be generated at this time" }, { "glytoucan_ac": "G90509QW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G90509QW] could be generated at this time" }, { "glytoucan_ac": "G90542MP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G90542MP] could be generated at this time" }, { "glytoucan_ac": "G90564EX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G28826SH", "dp": 10 } ], "links": [ { "target": "G90564EX", "source": "G28826SH", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G28826SH", "source": "G09782JM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90618SW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G57943ZV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G57943ZV", "dp": 11 }, { "id": "G90618SW", "dp": 11 } ], "links": [ { "target": "G90618SW", "source": "G57943ZV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57943ZV", "source": "G52934AK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90651NI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G90651NI] could be generated at this time" }, { "glytoucan_ac": "G90670ZD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G97093EP", "dp": 12 } ], "links": [ { "target": "G90670ZD", "source": "G97093EP", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G97093EP", "source": "G43433FA", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90672BM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G81328FA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G90672BM", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G90698PW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G34175ZP", "dp": 10 } ], "links": [ { "target": "G90698PW", "source": "G34175ZP", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G34175ZP", "source": "G01265XZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90703DJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G90703DJ] could be generated at this time" }, { "glytoucan_ac": "G90712YJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G23484GM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G69086TY", "dp": 12 }, { "id": "G42400JK", "dp": 13 }, { "id": "G23484GM", "dp": 14 }, { "id": "G90712YJ", "dp": 14 } ], "links": [ { "target": "G90712YJ", "source": "G23484GM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23484GM", "source": "G42400JK", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G42400JK", "source": "G69086TY", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90725ZC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G89993FE", "dp": 8 } ], "links": [ { "target": "G90725ZC", "source": "G89993FE", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G89993FE", "source": "G39213VZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90766ZI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G42193NQ]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G56748EO", "dp": 10 }, { "id": "G42193NQ", "dp": 11 }, { "id": "G90766ZI", "dp": 11 } ], "links": [ { "target": "G90766ZI", "source": "G42193NQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G42193NQ", "source": "G56748EO", "residue_affected": { "residue_id": "N373", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G56748EO", "source": "G20966TZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90769IN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G90774IS", "notes": [], "error": "No pathways for [G90774IS] could be generated at this time" }, { "glytoucan_ac": "G90779DH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56499YQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 }, { "id": "G56499YQ", "dp": 16 }, { "id": "G90779DH", "dp": 16 } ], "links": [ { "target": "G90779DH", "source": "G56499YQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56499YQ", "source": "G57955DP", "residue_affected": { "residue_id": "N228", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90784AP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G90784AP] could be generated at this time" }, { "glytoucan_ac": "G90790SM", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G19104OH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G90790SM", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G90797SN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G90825UM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 } ], "links": [ { "target": "G90825UM", "source": "G01856RL", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90833YY", "notes": [], "error": "No pathways for [G90833YY] could be generated at this time" }, { "glytoucan_ac": "G90840KY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G84390MS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G90840KY", "dp": 21 } ], "links": [] } , { "glytoucan_ac": "G90858SP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G41820ZZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G41820ZZ", "dp": 11 }, { "id": "G90858SP", "dp": 11 } ], "links": [ { "target": "G90858SP", "source": "G41820ZZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G41820ZZ", "source": "G45560HM", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90870DG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 } ], "links": [ { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90889KG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G17689DH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G17689DH", "dp": 12 }, { "id": "G90889KG", "dp": 12 } ], "links": [ { "target": "G90889KG", "source": "G17689DH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90950UC", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G20030CU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G90950UC", "dp": 9 } ], "links": [ { "target": "G90950UC", "source": "G20030CU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G90983BT", "notes": [], "error": "No pathways for [G90983BT] could be generated at this time" }, { "glytoucan_ac": "G90987JA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G90987JA] could be generated at this time" }, { "glytoucan_ac": "G91020ZU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G91023GB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91068DJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G91068DJ", "source": "G29011JC", "residue_affected": { "residue_id": "N359", "pubchem_name": "GlcNAc", "anomer": "a", "absolute": "D", "form_name": "GlcpNAc", "full_name": "α-D-GlcpNAc" }, "effect": "Adds α-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91074JT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59277TZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G59277TZ", "dp": 10 }, { "id": "G91074JT", "dp": 10 } ], "links": [ { "target": "G91074JT", "source": "G59277TZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59277TZ", "source": "G30159WR", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91089ZR", "notes": [], "error": "No pathways for [G91089ZR] could be generated at this time" }, { "glytoucan_ac": "G91144YH", "notes": [], "error": "No pathways for [G91144YH] could be generated at this time" }, { "glytoucan_ac": "G91147LL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 } ], "links": [ { "target": "G91147LL", "source": "G92359VA", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91151XY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23901NY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G23901NY", "dp": 11 }, { "id": "G91151XY", "dp": 11 } ], "links": [ { "target": "G91151XY", "source": "G23901NY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23901NY", "source": "G52934AK", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91156HJ", "notes": [], "error": "No pathways for [G91156HJ] could be generated at this time" }, { "glytoucan_ac": "G91159AV", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G12643KN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G34175ZP", "dp": 10 }, { "id": "G12643KN", "dp": 11 }, { "id": "G91159AV", "dp": 11 } ], "links": [ { "target": "G91159AV", "source": "G12643KN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G12643KN", "source": "G34175ZP", "residue_affected": { "residue_id": "N302", "pubchem_name": "GlcNAc", "anomer": "a", "absolute": "D", "form_name": "GlcpNAc", "full_name": "α-D-GlcpNAc" }, "effect": "Adds α-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G34175ZP", "source": "G01265XZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91180QG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G91193KQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G10385EY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G91193KQ", "dp": 16 } ], "links": [] } , { "glytoucan_ac": "G91199QX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G91199QX] could be generated at this time" }, { "glytoucan_ac": "G91208VE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G91208VE", "source": "G29011JC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91219PM", "notes": [], "error": "No pathways for [G91219PM] could be generated at this time" }, { "glytoucan_ac": "G91227VL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G91227VL] could be generated at this time" }, { "glytoucan_ac": "G91247WI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20030CU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G91247WI", "dp": 9 } ], "links": [ { "target": "G91247WI", "source": "G20030CU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91257NC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G91257NC] could be generated at this time" }, { "glytoucan_ac": "G91277HN", "notes": [], "error": "No pathways for [G91277HN] could be generated at this time" }, { "glytoucan_ac": "G91303GW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 } ], "links": [ { "target": "G91303GW", "source": "G45560HM", "residue_affected": { "residue_id": "N216", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91312MX", "notes": [], "error": "No pathways for [G91312MX] could be generated at this time" }, { "glytoucan_ac": "G91337ZP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 } ], "links": [ { "target": "G91337ZP", "source": "G58667NI", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91345JE", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G91365ZQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 } ], "links": [ { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91386RN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 }, { "id": "G31494OZ", "dp": 15 } ], "links": [ { "target": "G91386RN", "source": "G31494OZ", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G31494OZ", "source": "G60564DP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91388QD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66765ZA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G91388QD", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G91409SX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G13659RH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G91409SX", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G91413ZX", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G62765SF", "dp": 14 } ], "links": [ { "target": "G91413ZX", "source": "G62765SF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G62765SF", "source": "G04989WY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91452ZH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G91470EV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G26756VT", "dp": 11 } ], "links": [ { "target": "G91470EV", "source": "G26756VT", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G26756VT", "source": "G08863NS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91474EO", "notes": [], "error": "No pathways for [G91474EO] could be generated at this time" }, { "glytoucan_ac": "G91487MA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G87349YT", "dp": 13 }, { "id": "G95019KZ", "dp": 14 } ], "links": [ { "target": "G91487MA", "source": "G95019KZ", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G95019KZ", "source": "G87349YT", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G87349YT", "source": "G75049FP", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91511MZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G91511MZ", "source": "G11041DA", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91518OM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G78276SQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G78276SQ", "dp": 12 }, { "id": "G91518OM", "dp": 12 } ], "links": [ { "target": "G91518OM", "source": "G78276SQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78276SQ", "source": "G11041DA", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91550OH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G91550OH] could be generated at this time" }, { "glytoucan_ac": "G91599FN", "notes": [], "error": "No pathways for [G91599FN] could be generated at this time" }, { "glytoucan_ac": "G91624NX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G95695ZV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G91624NX", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G91704EI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30437YI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G91704EI", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G91704UR", "notes": [], "error": "No pathways for [G91704UR] could be generated at this time" }, { "glytoucan_ac": "G91729DG", "notes": [], "error": "No pathways for [G91729DG] could be generated at this time" }, { "glytoucan_ac": "G91731RP", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G14393TF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G91731RP", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G91827TX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40358EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G40358EZ", "dp": 11 }, { "id": "G91827TX", "dp": 11 } ], "links": [ { "target": "G91827TX", "source": "G40358EZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40358EZ", "source": "G00176HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91832SW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 } ], "links": [ { "target": "G91832SW", "source": "G85085MS", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91847ME", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G08520NM]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G91873GT", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 } ], "links": [ { "target": "G91873GT", "source": "G43299SD", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91905FJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 } ], "links": [ { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G91979JZ", "notes": [], "error": "No pathways for [G91979JZ] could be generated at this time" }, { "glytoucan_ac": "G92009KQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G92009KQ] could be generated at this time" }, { "glytoucan_ac": "G92024SL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G92024SL", "source": "G61751GZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92042VQ", "notes": [], "error": "No pathways for [G92042VQ] could be generated at this time" }, { "glytoucan_ac": "G92057EA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G96503EZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G92057EA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G92067KW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G40289RO]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G40289RO", "dp": 10 }, { "id": "G92067KW", "dp": 10 } ], "links": [ { "target": "G92067KW", "source": "G40289RO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G40289RO", "source": "G20966TZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92090QA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G92117KA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G57345HS]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G92117KA", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G92140GK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G92140GK] could be generated at this time" }, { "glytoucan_ac": "G92219PK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09670SR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G09670SR", "dp": 10 }, { "id": "G92219PK", "dp": 10 } ], "links": [ { "target": "G92219PK", "source": "G09670SR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92241FG", "notes": [], "error": "No pathways for [G92241FG] could be generated at this time" }, { "glytoucan_ac": "G92257YN", "notes": [], "error": "No pathways for [G92257YN] could be generated at this time" }, { "glytoucan_ac": "G92278VP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G48753IC]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G92278VP", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G92303LR", "notes": [], "error": "No pathways for [G92303LR] could be generated at this time" }, { "glytoucan_ac": "G92320FG", "notes": [], "error": "No pathways for [G92320FG] could be generated at this time" }, { "glytoucan_ac": "G92320PF", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G71679MX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G92320PF", "dp": 11 } ], "links": [ { "target": "G92320PF", "source": "G71679MX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92359VA", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 } ], "links": [ { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92383TF", "notes": [], "error": "No pathways for [G92383TF] could be generated at this time" }, { "glytoucan_ac": "G92413DG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G37385TT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G37385TT", "dp": 11 }, { "id": "G92413DG", "dp": 11 } ], "links": [ { "target": "G92413DG", "source": "G37385TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37385TT", "source": "G88417ED", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92442AF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G92466WU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 } ], "links": [ { "target": "G92466WU", "source": "G46638GC", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92485DY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G56516KW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G92485DY", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G92506EC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G54300AX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G92506EC", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G92527BY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G92527BY] could be generated at this time" }, { "glytoucan_ac": "G92574YO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 } ], "links": [ { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92575UZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G85767HW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G85767HW", "dp": 10 }, { "id": "G92575UZ", "dp": 10 } ], "links": [ { "target": "G92575UZ", "source": "G85767HW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G85767HW", "source": "G30159WR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92594VG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G27844UM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G92594VG", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G92612ZM", "notes": [], "error": "No pathways for [G92612ZM] could be generated at this time" }, { "glytoucan_ac": "G92617LF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 } ], "links": [ { "target": "G92617LF", "source": "G27919IH", "residue_affected": { "residue_id": "N206", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92627GM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G92627GM] could be generated at this time" }, { "glytoucan_ac": "G92681HQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 }, { "id": "G98852TR", "dp": 16 } ], "links": [ { "target": "G92681HQ", "source": "G98852TR", "residue_affected": { "residue_id": "N471", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G98852TR", "source": "G28957FB", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92684AL", "notes": [], "error": "No pathways for [G92684AL] could be generated at this time" }, { "glytoucan_ac": "G92695JQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G48658PB", "dp": 12 }, { "id": "G66572SF", "dp": 13 }, { "id": "G26877LE", "dp": 14 } ], "links": [ { "target": "G92695JQ", "source": "G26877LE", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G26877LE", "source": "G66572SF", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G66572SF", "source": "G48658PB", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G48658PB", "source": "G06131VP", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92712BL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75359HS]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G92712BL", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G92752RB", "notes": [], "error": "No pathways for [G92752RB] could be generated at this time" }, { "glytoucan_ac": "G92777SG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 } ], "links": [ { "target": "G92777SG", "source": "G62504BU", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92782XB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G92805XC", "notes": [], "error": "No pathways for [G92805XC] could be generated at this time" }, { "glytoucan_ac": "G92848CF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G92848CF] could be generated at this time" }, { "glytoucan_ac": "G92848QA", "notes": [], "error": "No pathways for [G92848QA] could be generated at this time" }, { "glytoucan_ac": "G92918FJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G92918FJ] could be generated at this time" }, { "glytoucan_ac": "G92940AF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G37597FW", "dp": 13 } ], "links": [ { "target": "G92940AF", "source": "G37597FW", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G37597FW", "source": "G98809PE", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G92983WW", "notes": [], "error": "No pathways for [G92983WW] could be generated at this time" }, { "glytoucan_ac": "G93029JO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20924UR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93029JO", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G93060PS", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 } ], "links": [ { "target": "G93060PS", "source": "G08520NM", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93075HW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G40289RO", "dp": 10 }, { "id": "G71102UV", "dp": 11 } ], "links": [ { "target": "G93075HW", "source": "G71102UV", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71102UV", "source": "G40289RO", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G40289RO", "source": "G20966TZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93088EE", "notes": [], "error": "No pathways for [G93088EE] could be generated at this time" }, { "glytoucan_ac": "G93107BF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G11637WL", "dp": 10 } ], "links": [ { "target": "G93107BF", "source": "G11637WL", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G11637WL", "source": "G16828VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93148GC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94838KN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93148GC", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G93162SU", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G51050LD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93162SU", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G93164KQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G04576KS]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G04576KS", "dp": 10 }, { "id": "G93164KQ", "dp": 10 } ], "links": [ { "target": "G93164KQ", "source": "G04576KS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G04576KS", "source": "G16828VN", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93176JI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 } ], "links": [ { "target": "G93176JI", "source": "G43299SD", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93193OD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 }, { "id": "G17473NR", "dp": 13 } ], "links": [ { "target": "G93193OD", "source": "G17473NR", "residue_affected": { "residue_id": "N267", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G17473NR", "source": "G10733HY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93204KY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G57943ZV", "dp": 11 } ], "links": [ { "target": "G93204KY", "source": "G57943ZV", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57943ZV", "source": "G52934AK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93211HX", "notes": [], "error": "No pathways for [G93211HX] could be generated at this time" }, { "glytoucan_ac": "G93237CR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 }, { "id": "G85085MS", "dp": 13 } ], "links": [ { "target": "G93237CR", "source": "G85085MS", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G85085MS", "source": "G74645FT", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93265QH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G57117TO", "dp": 8 } ], "links": [ { "target": "G93265QH", "source": "G57117TO", "residue_affected": { "residue_id": "N224", "pubchem_name": "Fuc", "anomer": "b", "absolute": "D", "form_name": "Fucp", "full_name": "β-D-Fucp" }, "effect": "Adds β-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G57117TO", "source": "G69411IG", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93279DZ", "notes": [], "error": "No pathways for [G93279DZ] could be generated at this time" }, { "glytoucan_ac": "G93279TH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G21246OH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G21246OH", "dp": 11 }, { "id": "G93279TH", "dp": 11 } ], "links": [ { "target": "G93279TH", "source": "G21246OH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G21246OH", "source": "G00176HZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93285LF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 }, { "id": "G74645FT", "dp": 12 } ], "links": [ { "target": "G93285LF", "source": "G74645FT", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74645FT", "source": "G43433FA", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93299MA", "notes": [], "error": "No pathways for [G93299MA] could be generated at this time" }, { "glytoucan_ac": "G93310KW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G59741XZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G59741XZ", "dp": 7 }, { "id": "G93310KW", "dp": 7 } ], "links": [ { "target": "G93310KW", "source": "G59741XZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59741XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93320VA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G26949IX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G26949IX", "dp": 11 }, { "id": "G93320VA", "dp": 11 } ], "links": [ { "target": "G93320VA", "source": "G26949IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26949IX", "source": "G78059CC", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93427DE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 } ], "links": [ { "target": "G93427DE", "source": "G29857RC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93446UA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23484GM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G71679MX", "dp": 11 }, { "id": "G69086TY", "dp": 12 }, { "id": "G42400JK", "dp": 13 }, { "id": "G23484GM", "dp": 14 }, { "id": "G93446UA", "dp": 14 } ], "links": [ { "target": "G93446UA", "source": "G23484GM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G23484GM", "source": "G42400JK", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G42400JK", "source": "G69086TY", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G69086TY", "source": "G71679MX", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71679MX", "source": "G00176HZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93447XI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G60941RE", "dp": 13 }, { "id": "G29931YE", "dp": 14 } ], "links": [ { "target": "G93447XI", "source": "G29931YE", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G29931YE", "source": "G60941RE", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60941RE", "source": "G75185NU", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93450TT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G93450TT] could be generated at this time" }, { "glytoucan_ac": "G93464IM", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G93464IM] could be generated at this time" }, { "glytoucan_ac": "G93500PH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 } ], "links": [ { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93516TF", "notes": [], "error": "No pathways for [G93516TF] could be generated at this time" }, { "glytoucan_ac": "G93527UH", "notes": [], "error": "No pathways for [G93527UH] could be generated at this time" }, { "glytoucan_ac": "G93553MJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G81328FA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93553MJ", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G93575MM", "notes": [], "error": "No pathways for [G93575MM] could be generated at this time" }, { "glytoucan_ac": "G93582HM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 } ], "links": [ { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93602DI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G79578JB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G93602DI", "dp": 12 } ], "links": [ { "target": "G93602DI", "source": "G79578JB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93624ZP", "notes": [], "error": "No pathways for [G93624ZP] could be generated at this time" }, { "glytoucan_ac": "G93638BI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G89877QI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G93638BI", "dp": 14 } ], "links": [ { "target": "G93638BI", "source": "G89877QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93638TT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G48767NV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G48767NV", "dp": 14 }, { "id": "G93638TT", "dp": 14 } ], "links": [ { "target": "G93638TT", "source": "G48767NV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G48767NV", "source": "G53812BX", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93646CO", "notes": [], "error": "No pathways for [G93646CO] could be generated at this time" }, { "glytoucan_ac": "G93655SG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G93655SG] could be generated at this time" }, { "glytoucan_ac": "G93692VT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G36519NW]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G01669LU", "dp": 12 }, { "id": "G36519NW", "dp": 13 }, { "id": "G93692VT", "dp": 13 } ], "links": [ { "target": "G93692VT", "source": "G36519NW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G36519NW", "source": "G01669LU", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G01669LU", "source": "G29857RC", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93698KA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G93698KA] could be generated at this time" }, { "glytoucan_ac": "G93707PO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G16828VN", "dp": 9 }, { "id": "G08187GM", "dp": 10 }, { "id": "G55974RB", "dp": 11 } ], "links": [ { "target": "G93707PO", "source": "G55974RB", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G55974RB", "source": "G08187GM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08187GM", "source": "G16828VN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G16828VN", "source": "G08520NM", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93722FJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G93746CY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G96063MG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 }, { "id": "G96063MG", "dp": 9 }, { "id": "G93746CY", "dp": 9 } ], "links": [ { "target": "G93746CY", "source": "G96063MG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93755GW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G93755GW", "source": "G66937TJ", "residue_affected": { "residue_id": "N240", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93758YP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G50364FV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93758YP", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G93767EH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53322JT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G53322JT", "dp": 11 }, { "id": "G93767EH", "dp": 11 } ], "links": [ { "target": "G93767EH", "source": "G53322JT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53322JT", "source": "G00176HZ", "residue_affected": { "residue_id": "N502", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93788SW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G79809MM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G93788SW", "dp": 11 } ], "links": [ { "target": "G93788SW", "source": "G79809MM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93802RY", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G48109OV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93802RY", "dp": 24 } ], "links": [] } , { "glytoucan_ac": "G93816OI", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G72112RK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93816OI", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G93824CM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G18768EK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G18768EK", "dp": 11 }, { "id": "G93824CM", "dp": 11 } ], "links": [ { "target": "G93824CM", "source": "G18768EK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G18768EK", "source": "G78803YD", "residue_affected": { "residue_id": "N78", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93839ET", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G15859AU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G93839ET", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G93906VI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G69905CP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G29434RB", "dp": 9 }, { "id": "G09670SR", "dp": 10 }, { "id": "G69905CP", "dp": 11 }, { "id": "G93906VI", "dp": 11 } ], "links": [ { "target": "G93906VI", "source": "G69905CP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G69905CP", "source": "G09670SR", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09670SR", "source": "G29434RB", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29434RB", "source": "G29011JC", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93933CG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G93933CG] could be generated at this time" }, { "glytoucan_ac": "G93986UQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G10182XZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G10182XZ", "dp": 7 }, { "id": "G93986UQ", "dp": 7 } ], "links": [ { "target": "G93986UQ", "source": "G10182XZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10182XZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G93993PE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G93993PE] could be generated at this time" }, { "glytoucan_ac": "G93994MR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G94013DC", "notes": [], "error": "No pathways for [G94013DC] could be generated at this time" }, { "glytoucan_ac": "G94019IV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G28218GE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G53752TA", "dp": 11 }, { "id": "G17689DH", "dp": 12 }, { "id": "G28218GE", "dp": 13 }, { "id": "G94019IV", "dp": 13 } ], "links": [ { "target": "G94019IV", "source": "G28218GE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G28218GE", "source": "G17689DH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G17689DH", "source": "G53752TA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53752TA", "source": "G68937TM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94027HD", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G72698LT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G59471TH", "dp": 8 }, { "id": "G82861UH", "dp": 9 }, { "id": "G72698LT", "dp": 10 }, { "id": "G94027HD", "dp": 10 } ], "links": [ { "target": "G94027HD", "source": "G72698LT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72698LT", "source": "G82861UH", "residue_affected": { "residue_id": "N32", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G82861UH", "source": "G59471TH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G59471TH", "source": "G39213VZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94045IP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 } ], "links": [ { "target": "G94045IP", "source": "G91023GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94047VH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 } ], "links": [ { "target": "G94047VH", "source": "G07995VK", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94116NC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G80147LG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G80147LG", "dp": 10 }, { "id": "G94116NC", "dp": 10 } ], "links": [ { "target": "G94116NC", "source": "G80147LG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G80147LG", "source": "G27919IH", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94132EL", "notes": [], "error": "No pathways for [G94132EL] could be generated at this time" }, { "glytoucan_ac": "G94156YI", "notes": [], "error": "No pathways for [G94156YI] could be generated at this time" }, { "glytoucan_ac": "G94163JZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G94163JZ] could be generated at this time" }, { "glytoucan_ac": "G94166QX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G99969SS]", "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 }, { "id": "G99969SS", "dp": 10 }, { "id": "G94166QX", "dp": 10 } ], "links": [ { "target": "G94166QX", "source": "G99969SS", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99969SS", "source": "G13151XE", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94232LU", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G16546ZZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G41331JX", "dp": 12 }, { "id": "G16546ZZ", "dp": 13 }, { "id": "G94232LU", "dp": 13 } ], "links": [ { "target": "G94232LU", "source": "G16546ZZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16546ZZ", "source": "G41331JX", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G41331JX", "source": "G25520XG", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94252JR", "notes": [], "error": "No pathways for [G94252JR] could be generated at this time" }, { "glytoucan_ac": "G94277TH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09118YK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G04989WY", "dp": 13 }, { "id": "G16150CJ", "dp": 14 }, { "id": "G03895SR", "dp": 15 }, { "id": "G09118YK", "dp": 16 }, { "id": "G94277TH", "dp": 16 } ], "links": [ { "target": "G94277TH", "source": "G09118YK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09118YK", "source": "G03895SR", "residue_affected": { "residue_id": "N82", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G03895SR", "source": "G16150CJ", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G16150CJ", "source": "G04989WY", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G04989WY", "source": "G86357DX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94297FY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 } ], "links": [ { "target": "G94297FY", "source": "G29492IF", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94363RH", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G08194HH", "dp": 14 }, { "id": "G14782PJ", "dp": 15 }, { "id": "G79950YS", "dp": 16 } ], "links": [ { "target": "G94363RH", "source": "G79950YS", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79950YS", "source": "G14782PJ", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G14782PJ", "source": "G08194HH", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G08194HH", "source": "G18938DW", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94394GK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G94394GK] could be generated at this time" }, { "glytoucan_ac": "G94401RA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G94401RA", "source": "G36191CD", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94423NC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26881SV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G94423NC", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G94428FR", "notes": [], "error": "No pathways for [G94428FR] could be generated at this time" }, { "glytoucan_ac": "G94481KZ", "notes": [], "error": "No pathways for [G94481KZ] could be generated at this time" }, { "glytoucan_ac": "G94490EL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G94490EL] could be generated at this time" }, { "glytoucan_ac": "G94497JT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G31010RQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G31010RQ", "dp": 11 }, { "id": "G94497JT", "dp": 11 } ], "links": [ { "target": "G94497JT", "source": "G31010RQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G31010RQ", "source": "G08863NS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94531EZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 } ], "links": [ { "target": "G94531EZ", "source": "G50489VC", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94541XJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G58473KL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G94541XJ", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G94547KR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G14127XU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 }, { "id": "G14127XU", "dp": 13 }, { "id": "G94547KR", "dp": 13 } ], "links": [ { "target": "G94547KR", "source": "G14127XU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G14127XU", "source": "G91023GB", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94600JO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G94600JO", "source": "G61751GZ", "residue_affected": { "residue_id": "N256", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G94610SC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G94610SC] could be generated at this time" }, { "glytoucan_ac": "G94626AX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G09576QH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G94626AX", "dp": 20 } ], "links": [] } , { "glytoucan_ac": "G94671TE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G98809PE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G94671TE", "dp": 12 } ], "links": [ { "target": "G94671TE", "source": "G98809PE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94679TQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G94679TQ] could be generated at this time" }, { "glytoucan_ac": "G94692TX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G08340FW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G08340FW", "dp": 8 }, { "id": "G94692TX", "dp": 8 } ], "links": [ { "target": "G94692TX", "source": "G08340FW", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G08340FW", "source": "G39089YD", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G94718HG", "notes": [], "error": "No pathways for [G94718HG] could be generated at this time" }, { "glytoucan_ac": "G94733WZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 } ], "links": [ { "target": "G94733WZ", "source": "G89877QI", "residue_affected": { "residue_id": "N203", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94734OT", "notes": [], "error": "No pathways for [G94734OT] could be generated at this time" }, { "glytoucan_ac": "G94736EY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G71835BN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G71835BN", "dp": 10 }, { "id": "G94736EY", "dp": 10 } ], "links": [ { "target": "G94736EY", "source": "G71835BN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G71835BN", "source": "G36191CD", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94748CQ", "notes": [], "error": "No pathways for [G94748CQ] could be generated at this time" }, { "glytoucan_ac": "G94754ZO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G94770AN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G33862NZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G94770AN", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G94773HW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G94804ZC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G60660BN]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G57466QX", "dp": 13 }, { "id": "G10228OD", "dp": 14 }, { "id": "G60660BN", "dp": 15 }, { "id": "G94804ZC", "dp": 15 } ], "links": [ { "target": "G94804ZC", "source": "G60660BN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60660BN", "source": "G10228OD", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G10228OD", "source": "G57466QX", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G57466QX", "source": "G86357DX", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94806YM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G07162IJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G94806YM", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G94809SW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G62326NX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G94809SW", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G94816EL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86298IX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G47175EF", "dp": 11 }, { "id": "G60215UL", "dp": 12 }, { "id": "G86298IX", "dp": 13 }, { "id": "G94816EL", "dp": 13 } ], "links": [ { "target": "G94816EL", "source": "G86298IX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86298IX", "source": "G60215UL", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G60215UL", "source": "G47175EF", "residue_affected": { "residue_id": "N104", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G47175EF", "source": "G78059CC", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94827SR", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G90348RI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 }, { "id": "G90348RI", "dp": 12 }, { "id": "G94827SR", "dp": 12 } ], "links": [ { "target": "G94827SR", "source": "G90348RI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90348RI", "source": "G11041DA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94838KN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G94838KN] could be generated at this time" }, { "glytoucan_ac": "G94876HV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G94876HV] could be generated at this time" }, { "glytoucan_ac": "G94926TV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20170YB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G34838RM", "dp": 10 }, { "id": "G63585HN", "dp": 11 }, { "id": "G20170YB", "dp": 12 }, { "id": "G94926TV", "dp": 12 } ], "links": [ { "target": "G94926TV", "source": "G20170YB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20170YB", "source": "G63585HN", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G63585HN", "source": "G34838RM", "residue_affected": { "residue_id": "N74", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G34838RM", "source": "G80393PG", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94935XB", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G94935XB] could be generated at this time" }, { "glytoucan_ac": "G94946LG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G44946WH]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G94946LG", "dp": 10 } ], "links": [ { "target": "G94946LG", "source": "G44946WH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94959AA", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G47279LF]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G94959AA", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G94975UV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G92574YO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G92574YO", "dp": 17 }, { "id": "G94975UV", "dp": 17 } ], "links": [ { "target": "G94975UV", "source": "G92574YO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G92574YO", "source": "G32287FD", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G94979RS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G94979RS] could be generated at this time" }, { "glytoucan_ac": "G95019KZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G87349YT", "dp": 13 } ], "links": [ { "target": "G95019KZ", "source": "G87349YT", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G87349YT", "source": "G75049FP", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95081VM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 } ], "links": [ { "target": "G95081VM", "source": "G66937TJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95109CV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34972BB]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 }, { "id": "G34972BB", "dp": 15 }, { "id": "G95109CV", "dp": 15 } ], "links": [ { "target": "G95109CV", "source": "G34972BB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34972BB", "source": "G91905FJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95186HE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78030KJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G78030KJ", "dp": 14 }, { "id": "G95186HE", "dp": 14 } ], "links": [ { "target": "G95186HE", "source": "G78030KJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78030KJ", "source": "G53812BX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95201NS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G12740VA", "dp": 10 }, { "id": "G04544OS", "dp": 11 } ], "links": [ { "target": "G95201NS", "source": "G04544OS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04544OS", "source": "G12740VA", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G12740VA", "source": "G09782JM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95222PD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75049FP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 }, { "id": "G95222PD", "dp": 12 } ], "links": [ { "target": "G95222PD", "source": "G75049FP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95227SJ", "notes": [], "error": "No pathways for [G95227SJ] could be generated at this time" }, { "glytoucan_ac": "G95233RZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G38407OC", "dp": 12 } ], "links": [ { "target": "G95233RZ", "source": "G38407OC", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38407OC", "source": "G20815TK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95251MI", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90784AP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95251MI", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G95260HV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G95272YB", "notes": [], "error": "No pathways for [G95272YB] could be generated at this time" }, { "glytoucan_ac": "G95298UR", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G95298UR] could be generated at this time" }, { "glytoucan_ac": "G95333ZG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G19104OH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95333ZG", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G95335FK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G95375WT", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G95617FJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G95617FJ", "dp": 12 }, { "id": "G95375WT", "dp": 12 } ], "links": [ { "target": "G95375WT", "source": "G95617FJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G95617FJ", "source": "G25520XG", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95382MF", "notes": [], "error": "No pathways for [G95382MF] could be generated at this time" }, { "glytoucan_ac": "G95393JS", "notes": [], "error": "No pathways for [G95393JS] could be generated at this time" }, { "glytoucan_ac": "G95404EQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G35310KA", "dp": 11 }, { "id": "G50774CV", "dp": 12 }, { "id": "G81663ZI", "dp": 13 }, { "id": "G11953VE", "dp": 14 }, { "id": "G40606GB", "dp": 15 }, { "id": "G90284FM", "dp": 16 } ], "links": [ { "target": "G95404EQ", "source": "G90284FM", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G90284FM", "source": "G40606GB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G40606GB", "source": "G11953VE", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11953VE", "source": "G81663ZI", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G81663ZI", "source": "G50774CV", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G50774CV", "source": "G35310KA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G35310KA", "source": "G79609RF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95423TN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G38395YJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G38395YJ", "dp": 14 }, { "id": "G95423TN", "dp": 14 } ], "links": [ { "target": "G95423TN", "source": "G38395YJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G38395YJ", "source": "G00909PI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95440SV", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59579TL]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G78797VK", "dp": 15 }, { "id": "G02311IE", "dp": 16 }, { "id": "G86753CK", "dp": 17 }, { "id": "G59579TL", "dp": 18 }, { "id": "G95440SV", "dp": 18 } ], "links": [ { "target": "G95440SV", "source": "G59579TL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G59579TL", "source": "G86753CK", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86753CK", "source": "G02311IE", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G02311IE", "source": "G78797VK", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78797VK", "source": "G63889NK", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95462VZ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G36223VW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95462VZ", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G95473VJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G09150LP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G26182BM", "dp": 8 }, { "id": "G61207RZ", "dp": 9 }, { "id": "G44946WH", "dp": 10 }, { "id": "G88948CY", "dp": 11 }, { "id": "G09150LP", "dp": 12 }, { "id": "G95473VJ", "dp": 12 } ], "links": [ { "target": "G95473VJ", "source": "G09150LP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G09150LP", "source": "G88948CY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88948CY", "source": "G44946WH", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G44946WH", "source": "G61207RZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G61207RZ", "source": "G26182BM", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G26182BM", "source": "G07483YN", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95490LA", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G95490LA", "source": "G18938DW", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95512GZ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G60564DP", "dp": 14 }, { "id": "G31494OZ", "dp": 15 }, { "id": "G91386RN", "dp": 16 } ], "links": [ { "target": "G95512GZ", "source": "G91386RN", "residue_affected": { "residue_id": "N200", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] }, { "target": "G91386RN", "source": "G31494OZ", "residue_affected": { "residue_id": "N71", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G31494OZ", "source": "G60564DP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G60564DP", "source": "G18938DW", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95528UC", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G60103QI]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G54611ZT", "dp": 11 }, { "id": "G60103QI", "dp": 12 }, { "id": "G95528UC", "dp": 12 } ], "links": [ { "target": "G95528UC", "source": "G60103QI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60103QI", "source": "G54611ZT", "residue_affected": { "residue_id": "N266", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95536UW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G12241WD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95536UW", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G95542JQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G95542JQ] could be generated at this time" }, { "glytoucan_ac": "G95617FJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 } ], "links": [ { "target": "G95617FJ", "source": "G25520XG", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95619PX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G87807PF]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95619PX", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G95633RJ", "notes": [], "error": "No pathways for [G95633RJ] could be generated at this time" }, { "glytoucan_ac": "G95639FY", "notes": [], "error": "No pathways for [G95639FY] could be generated at this time" }, { "glytoucan_ac": "G95655OA", "notes": [], "error": "No pathways for [G95655OA] could be generated at this time" }, { "glytoucan_ac": "G95658PH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G95658PH] could be generated at this time" }, { "glytoucan_ac": "G95677OZ", "notes": [], "error": "No pathways for [G95677OZ] could be generated at this time" }, { "glytoucan_ac": "G95695ZV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G95695ZV] could be generated at this time" }, { "glytoucan_ac": "G95713LQ", "notes": [], "error": "No pathways for [G95713LQ] could be generated at this time" }, { "glytoucan_ac": "G95732UV", "notes": [], "error": "No pathways for [G95732UV] could be generated at this time" }, { "glytoucan_ac": "G95782RB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G37140SO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G37140SO", "dp": 10 }, { "id": "G95782RB", "dp": 10 } ], "links": [ { "target": "G95782RB", "source": "G37140SO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G37140SO", "source": "G93500PH", "residue_affected": { "residue_id": "N31", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95786NX", "notes": [], "error": "No pathways for [G95786NX] could be generated at this time" }, { "glytoucan_ac": "G95788IL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G95849ZD", "notes": [], "error": "No pathways for [G95849ZD] could be generated at this time" }, { "glytoucan_ac": "G95861WO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G95898GD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 } ], "links": [ { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95901MC", "notes": [], "error": "No pathways for [G95901MC] could be generated at this time" }, { "glytoucan_ac": "G95910WJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G36223VW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95910WJ", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G95919TI", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G30651IU", "dp": 13 } ], "links": [ { "target": "G95919TI", "source": "G30651IU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G30651IU", "source": "G86357DX", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95940WS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G92918FJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95940WS", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G95952ST", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G34508UC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95952ST", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G95956WE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G42548XF", "dp": 7 } ], "links": [ { "target": "G95956WE", "source": "G42548XF", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G42548XF", "source": "G61751GZ", "residue_affected": { "residue_id": "N204", "pubchem_name": "Man", "anomer": "a", "absolute": "D", "form_name": "Manp", "full_name": "α-D-Manp" }, "effect": "Adds α-D-Manp", "enzymes": [] } ] } , { "glytoucan_ac": "G95963DM", "notes": [], "error": "No pathways for [G95963DM] could be generated at this time" }, { "glytoucan_ac": "G95984JN", "notes": [], "error": "No pathways for [G95984JN] could be generated at this time" }, { "glytoucan_ac": "G95989NQ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G95989NQ] could be generated at this time" }, { "glytoucan_ac": "G95994EE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G77475MM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G95994EE", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G95997CK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10716SX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G88417ED", "dp": 10 }, { "id": "G37385TT", "dp": 11 }, { "id": "G10716SX", "dp": 12 }, { "id": "G95997CK", "dp": 12 } ], "links": [ { "target": "G95997CK", "source": "G10716SX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10716SX", "source": "G37385TT", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G37385TT", "source": "G88417ED", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G88417ED", "source": "G88461FF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G95998QK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G09446VC", "dp": 10 }, { "id": "G49827WK", "dp": 11 } ], "links": [ { "target": "G95998QK", "source": "G49827WK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G49827WK", "source": "G09446VC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G09446VC", "source": "G30159WR", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96004HC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G32065BG]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96004HC", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G96024GG", "notes": [], "error": "No pathways for [G96024GG] could be generated at this time" }, { "glytoucan_ac": "G96045AL", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G57955DP]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G86357DX", "dp": 12 }, { "id": "G19726AG", "dp": 13 }, { "id": "G38022PE", "dp": 14 }, { "id": "G57955DP", "dp": 15 }, { "id": "G96045AL", "dp": 15 } ], "links": [ { "target": "G96045AL", "source": "G57955DP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G57955DP", "source": "G38022PE", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G38022PE", "source": "G19726AG", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G19726AG", "source": "G86357DX", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G86357DX", "source": "G10691MJ", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96060VZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G08076GP]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G96060VZ", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G96063MG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 } ], "links": [ { "target": "G96063MG", "source": "G67045LB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96079QX", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G54956ME]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96079QX", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G96081GH", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G59752BW]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96081GH", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G96091LW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G93500PH", "dp": 9 }, { "id": "G07228BR", "dp": 10 } ], "links": [ { "target": "G96091LW", "source": "G07228BR", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07228BR", "source": "G93500PH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G93500PH", "source": "G29011JC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96113SZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G10209QU", "dp": 8 }, { "id": "G45262QY", "dp": 9 }, { "id": "G82420SH", "dp": 10 } ], "links": [ { "target": "G96113SZ", "source": "G82420SH", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82420SH", "source": "G45262QY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G45262QY", "source": "G10209QU", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G10209QU", "source": "G07483YN", "residue_affected": { "residue_id": "N44", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96122UB", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16759KR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G96122UB", "dp": 9 } ], "links": [ { "target": "G96122UB", "source": "G16759KR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96153DN", "notes": [], "error": "No pathways for [G96153DN] could be generated at this time" }, { "glytoucan_ac": "G96168ED", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G54611ZT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G54611ZT", "dp": 11 }, { "id": "G96168ED", "dp": 11 } ], "links": [ { "target": "G96168ED", "source": "G54611ZT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G54611ZT", "source": "G78059CC", "residue_affected": { "residue_id": "N45", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96175KT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94047VH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 }, { "id": "G94047VH", "dp": 11 }, { "id": "G96175KT", "dp": 11 } ], "links": [ { "target": "G96175KT", "source": "G94047VH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G94047VH", "source": "G07995VK", "residue_affected": { "residue_id": "N479", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96223WK", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 } ], "links": [ { "target": "G96223WK", "source": "G47782UT", "residue_affected": { "residue_id": "N52", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96235XM", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G96235XM] could be generated at this time" }, { "glytoucan_ac": "G96251ED", "notes": [], "error": "No pathways for [G96251ED] could be generated at this time" }, { "glytoucan_ac": "G96370EB", "notes": [], "error": "No pathways for [G96370EB] could be generated at this time" }, { "glytoucan_ac": "G96417PJ", "notes": [], "error": "No pathways for [G96417PJ] could be generated at this time" }, { "glytoucan_ac": "G96439CH", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G60419KX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G96963QG", "dp": 12 }, { "id": "G73759SD", "dp": 13 }, { "id": "G60419KX", "dp": 14 }, { "id": "G96439CH", "dp": 14 } ], "links": [ { "target": "G96439CH", "source": "G60419KX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G60419KX", "source": "G73759SD", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G73759SD", "source": "G96963QG", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96444IW", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [G84363RQ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G07995VK", "dp": 10 }, { "id": "G84363RQ", "dp": 11 }, { "id": "G96444IW", "dp": 11 } ], "links": [ { "target": "G96444IW", "source": "G84363RQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G84363RQ", "source": "G07995VK", "residue_affected": { "residue_id": "N237", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G07995VK", "source": "G36191CD", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96445EY", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G84163ZT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96445EY", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G96484SJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G29492IF", "dp": 8 }, { "id": "G09782JM", "dp": 9 }, { "id": "G21755KD", "dp": 10 } ], "links": [ { "target": "G96484SJ", "source": "G21755KD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G21755KD", "source": "G09782JM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G09782JM", "source": "G29492IF", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G29492IF", "source": "G69411IG", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96503EZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G96503EZ] could be generated at this time" }, { "glytoucan_ac": "G96508BN", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G41953RN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96508BN", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G96570OI", "notes": [], "error": "No pathways for [G96570OI] could be generated at this time" }, { "glytoucan_ac": "G96671XB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G96671XB] could be generated at this time" }, { "glytoucan_ac": "G96674LJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G32287FD", "dp": 16 }, { "id": "G50489VC", "dp": 17 } ], "links": [ { "target": "G96674LJ", "source": "G50489VC", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G50489VC", "source": "G32287FD", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G32287FD", "source": "G76842ZR", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96677EZ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G96680QM", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G08896RO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96680QM", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G96715HA", "notes": [], "error": "No pathways for [G96715HA] could be generated at this time" }, { "glytoucan_ac": "G96719MC", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G96719MC] could be generated at this time" }, { "glytoucan_ac": "G96738MG", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G81738MQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96738MG", "dp": 10 } ], "links": [] } , { "glytoucan_ac": "G96768SN", "notes": [], "error": "No pathways for [G96768SN] could be generated at this time" }, { "glytoucan_ac": "G96786JM", "notes": [], "error": "No pathways for [G96786JM] could be generated at this time" }, { "glytoucan_ac": "G96794ZC", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53812BX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G96794ZC", "dp": 13 } ], "links": [ { "target": "G96794ZC", "source": "G53812BX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96841SQ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G83635VI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96841SQ", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G96852FA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G83635VI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G96852FA", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G96852SM", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75412QZ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G75412QZ", "dp": 14 }, { "id": "G96852SM", "dp": 14 } ], "links": [ { "target": "G96852SM", "source": "G75412QZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75412QZ", "source": "G18938DW", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96861IW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G96866DI", "notes": [], "error": "No pathways for [G96866DI] could be generated at this time" }, { "glytoucan_ac": "G96896RL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G63787RZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G27919IH", "dp": 9 }, { "id": "G63787RZ", "dp": 10 }, { "id": "G96896RL", "dp": 10 } ], "links": [ { "target": "G96896RL", "source": "G63787RZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63787RZ", "source": "G27919IH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G27919IH", "source": "G80858MF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96906RY", "notes": [], "error": "No pathways for [G96906RY] could be generated at this time" }, { "glytoucan_ac": "G96915NW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G51793MY]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G51793MY", "dp": 11 }, { "id": "G96915NW", "dp": 11 } ], "links": [ { "target": "G96915NW", "source": "G51793MY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G51793MY", "source": "G45560HM", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96916QO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G16529MG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G16529MG", "dp": 14 }, { "id": "G96916QO", "dp": 14 } ], "links": [ { "target": "G96916QO", "source": "G16529MG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G16529MG", "source": "G56549DH", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96919WB", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G96919WB] could be generated at this time" }, { "glytoucan_ac": "G96921ZU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G11041DA", "dp": 11 } ], "links": [ { "target": "G96921ZU", "source": "G11041DA", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11041DA", "source": "G43694RQ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96925LL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G96925LL] could be generated at this time" }, { "glytoucan_ac": "G96931TH", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 }, { "id": "G30723RE", "dp": 11 } ], "links": [ { "target": "G96931TH", "source": "G30723RE", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G30723RE", "source": "G68937TM", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G96963QG", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 } ], "links": [ { "target": "G96963QG", "source": "G79809MM", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97023FS", "notes": [], "error": "No pathways for [G97023FS] could be generated at this time" }, { "glytoucan_ac": "G97039HI", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G97039HI] could be generated at this time" }, { "glytoucan_ac": "G97066VR", "notes": [], "error": "No pathways for [G97066VR] could be generated at this time" }, { "glytoucan_ac": "G97078FW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 } ], "links": [ { "target": "G97078FW", "source": "G56549DH", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97093EP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G27123NH", "dp": 10 }, { "id": "G43433FA", "dp": 11 } ], "links": [ { "target": "G97093EP", "source": "G43433FA", "residue_affected": { "residue_id": "N257", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G43433FA", "source": "G27123NH", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G27123NH", "source": "G46638GC", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97105ZG", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G91023GB", "dp": 12 } ], "links": [ { "target": "G97105ZG", "source": "G91023GB", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G91023GB", "source": "G25520XG", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97109LT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G76478FT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G76478FT", "dp": 11 }, { "id": "G97109LT", "dp": 11 } ], "links": [ { "target": "G97109LT", "source": "G76478FT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76478FT", "source": "G78059CC", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97123TW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61575RT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G82050MN", "dp": 13 }, { "id": "G61575RT", "dp": 14 }, { "id": "G97123TW", "dp": 14 } ], "links": [ { "target": "G97123TW", "source": "G61575RT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61575RT", "source": "G82050MN", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G82050MN", "source": "G84376FR", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97130PD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90870DG]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G97130PD", "dp": 11 } ], "links": [ { "target": "G97130PD", "source": "G90870DG", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97159KS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 } ], "links": [ { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97166FW", "notes": [], "error": "No pathways for [G97166FW] could be generated at this time" }, { "glytoucan_ac": "G97179UV", "notes": [], "error": "No pathways for [G97179UV] could be generated at this time" }, { "glytoucan_ac": "G97185IQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G10770RR]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G03951JJ", "dp": 12 }, { "id": "G20926BB", "dp": 13 }, { "id": "G82033VN", "dp": 14 }, { "id": "G10770RR", "dp": 15 }, { "id": "G97185IQ", "dp": 15 } ], "links": [ { "target": "G97185IQ", "source": "G10770RR", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G10770RR", "source": "G82033VN", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G82033VN", "source": "G20926BB", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20926BB", "source": "G03951JJ", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G03951JJ", "source": "G79809MM", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97267JL", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 } ], "links": [ { "target": "G97267JL", "source": "G69411IG", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97292GW", "notes": [], "error": "No pathways for [G97292GW] could be generated at this time" }, { "glytoucan_ac": "G97309BN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G97309BN] could be generated at this time" }, { "glytoucan_ac": "G97352VJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G98809PE]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G97352VJ", "dp": 12 } ], "links": [ { "target": "G97352VJ", "source": "G98809PE", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97353GO", "notes": [], "error": "No pathways for [G97353GO] could be generated at this time" }, { "glytoucan_ac": "G97423PY", "notes": [], "error": "No pathways for [G97423PY] could be generated at this time" }, { "glytoucan_ac": "G97453GF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G97453GF] could be generated at this time" }, { "glytoucan_ac": "G97455PT", "notes": [], "error": "No pathways for [G97455PT] could be generated at this time" }, { "glytoucan_ac": "G97511SW", "notes": [], "error": "No pathways for [G97511SW] could be generated at this time" }, { "glytoucan_ac": "G97523ON", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G94610SC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G97523ON", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G97545UW", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G37046CZ", "dp": 11 }, { "id": "G14959WS", "dp": 12 }, { "id": "G95898GD", "dp": 13 }, { "id": "G01923XE", "dp": 14 }, { "id": "G32808NL", "dp": 15 } ], "links": [ { "target": "G97545UW", "source": "G32808NL", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G32808NL", "source": "G01923XE", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01923XE", "source": "G95898GD", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G95898GD", "source": "G14959WS", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G14959WS", "source": "G37046CZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G37046CZ", "source": "G32305RZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97547WF", "notes": [], "error": "No pathways for [G97547WF] could be generated at this time" }, { "glytoucan_ac": "G97548TA", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G99645NK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G97548TA", "dp": 11 } ], "links": [ { "target": "G97548TA", "source": "G99645NK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97553BW", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G30460NZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30460NZ", "dp": 11 }, { "id": "G97553BW", "dp": 11 } ], "links": [ { "target": "G97553BW", "source": "G30460NZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30460NZ", "source": "G78059CC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97575FW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G53962WT]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G97575FW", "dp": 9 } ], "links": [] } , { "glytoucan_ac": "G97616MU", "notes": [], "error": "No pathways for [G97616MU] could be generated at this time" }, { "glytoucan_ac": "G97628LQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G50078RT", "dp": 12 } ], "links": [ { "target": "G97628LQ", "source": "G50078RT", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G50078RT", "source": "G79809MM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97645ML", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G96719MC]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G97645ML", "dp": 19 } ], "links": [] } , { "glytoucan_ac": "G97674NY", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 } ], "links": [ { "target": "G97674NY", "source": "G89877QI", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97682ZN", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G59915YZ", "dp": 11 } ], "links": [ { "target": "G97682ZN", "source": "G59915YZ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G59915YZ", "source": "G79609RF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97686QU", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G97686QU] could be generated at this time" }, { "glytoucan_ac": "G97709WW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G78030KJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G78030KJ", "dp": 14 }, { "id": "G97709WW", "dp": 14 } ], "links": [ { "target": "G97709WW", "source": "G78030KJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78030KJ", "source": "G53812BX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97720QM", "notes": [], "error": "No pathways for [G97720QM] could be generated at this time" }, { "glytoucan_ac": "G97765TT", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 } ], "links": [ { "target": "G97765TT", "source": "G18219CJ", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97814YJ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G25140TA]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G22795QB", "dp": 10 }, { "id": "G25140TA", "dp": 11 }, { "id": "G97814YJ", "dp": 11 } ], "links": [ { "target": "G97814YJ", "source": "G25140TA", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G25140TA", "source": "G22795QB", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G22795QB", "source": "G72718TT", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97842ZO", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G78173WX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G43694RQ", "dp": 10 }, { "id": "G78173WX", "dp": 11 }, { "id": "G97842ZO", "dp": 11 } ], "links": [ { "target": "G97842ZO", "source": "G78173WX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G78173WX", "source": "G43694RQ", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G43694RQ", "source": "G58667NI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97865QM", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G97865QM] could be generated at this time" }, { "glytoucan_ac": "G97895RK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 } ], "links": [ { "target": "G97895RK", "source": "G79578JB", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97910HZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G72821WX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G72821WX", "dp": 9 }, { "id": "G97910HZ", "dp": 9 } ], "links": [ { "target": "G97910HZ", "source": "G72821WX", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G72821WX", "source": "G12398HZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97947UQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G04791QM", "dp": 9 }, { "id": "G91365ZQ", "dp": 10 }, { "id": "G14047PA", "dp": 11 } ], "links": [ { "target": "G97947UQ", "source": "G14047PA", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G14047PA", "source": "G91365ZQ", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91365ZQ", "source": "G04791QM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G04791QM", "source": "G66937TJ", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97948YW", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G34905OT]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G77639OD", "dp": 10 }, { "id": "G34905OT", "dp": 11 }, { "id": "G97948YW", "dp": 11 } ], "links": [ { "target": "G97948YW", "source": "G34905OT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G34905OT", "source": "G77639OD", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G77639OD", "source": "G20030CU", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97958KV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G06969ZX", "dp": 10 } ], "links": [ { "target": "G97958KV", "source": "G06969ZX", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G06969ZX", "source": "G46638GC", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G97970WP", "notes": [ "reducing end mismatch [a-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G97996SP", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G80393PG", "dp": 9 }, { "id": "G08577ZR", "dp": 10 }, { "id": "G97159KS", "dp": 11 }, { "id": "G45359RY", "dp": 12 }, { "id": "G93582HM", "dp": 13 }, { "id": "G91905FJ", "dp": 14 } ], "links": [ { "target": "G97996SP", "source": "G91905FJ", "residue_affected": { "residue_id": "N57", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G91905FJ", "source": "G93582HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G93582HM", "source": "G45359RY", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45359RY", "source": "G97159KS", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G97159KS", "source": "G08577ZR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08577ZR", "source": "G80393PG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G80393PG", "source": "G10219AA", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98030BR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G51066TO]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G10733HY", "dp": 12 }, { "id": "G51066TO", "dp": 13 }, { "id": "G98030BR", "dp": 13 } ], "links": [ { "target": "G98030BR", "source": "G51066TO", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G51066TO", "source": "G10733HY", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G10733HY", "source": "G25520XG", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98048XD", "notes": [], "error": "No pathways for [G98048XD] could be generated at this time" }, { "glytoucan_ac": "G98066UT", "notes": [], "error": "No pathways for [G98066UT] could be generated at this time" }, { "glytoucan_ac": "G98115AV", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G98115AV] could be generated at this time" }, { "glytoucan_ac": "G98117HW", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G98117HW] could be generated at this time" }, { "glytoucan_ac": "G98140IX", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 } ], "links": [ { "target": "G98140IX", "source": "G61751GZ", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98190RD", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 } ], "links": [ { "target": "G98190RD", "source": "G52934AK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98207CW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84777MO]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G98207CW", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G98212GQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G77252PU]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G16759KR", "dp": 9 }, { "id": "G45560HM", "dp": 10 }, { "id": "G77252PU", "dp": 11 }, { "id": "G98212GQ", "dp": 11 } ], "links": [ { "target": "G98212GQ", "source": "G77252PU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G77252PU", "source": "G45560HM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G45560HM", "source": "G16759KR", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G16759KR", "source": "G66937TJ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98217YG", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G66265KN]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G33262YZ", "dp": 11 }, { "id": "G66265KN", "dp": 12 }, { "id": "G98217YG", "dp": 12 } ], "links": [ { "target": "G98217YG", "source": "G66265KN", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66265KN", "source": "G33262YZ", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G33262YZ", "source": "G52934AK", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98218PF", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G68937TM", "dp": 10 } ], "links": [ { "target": "G98218PF", "source": "G68937TM", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G68937TM", "source": "G58667NI", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98223HN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90825UM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G01856RL", "dp": 10 }, { "id": "G90825UM", "dp": 11 }, { "id": "G98223HN", "dp": 11 } ], "links": [ { "target": "G98223HN", "source": "G90825UM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G90825UM", "source": "G01856RL", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G01856RL", "source": "G36191CD", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98256YA", "notes": [], "error": "No pathways for [G98256YA] could be generated at this time" }, { "glytoucan_ac": "G98292JT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43299SD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G29011JC", "dp": 8 }, { "id": "G43299SD", "dp": 9 }, { "id": "G98292JT", "dp": 9 } ], "links": [ { "target": "G98292JT", "source": "G43299SD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43299SD", "source": "G29011JC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G29011JC", "source": "G39213VZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98366ZJ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G99074EO", "dp": 13 } ], "links": [ { "target": "G98366ZJ", "source": "G99074EO", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98369DU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G24984RR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G98369DU", "dp": 11 } ], "links": [] } , { "glytoucan_ac": "G98380JU", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 }, { "id": "G59915YZ", "dp": 11 } ], "links": [ { "target": "G98380JU", "source": "G59915YZ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G59915YZ", "source": "G79609RF", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98419CX", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G97765TT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G18219CJ", "dp": 11 }, { "id": "G97765TT", "dp": 12 }, { "id": "G98419CX", "dp": 12 } ], "links": [ { "target": "G98419CX", "source": "G97765TT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G97765TT", "source": "G18219CJ", "residue_affected": { "residue_id": "N97", "pubchem_name": "GalNAc", "anomer": "a", "absolute": "D", "form_name": "GalpNAc", "full_name": "α-D-GalpNAc" }, "effect": "Adds α-D-GalpNAc", "enzymes": [] }, { "target": "G18219CJ", "source": "G78059CC", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98452OT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G22865RK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G98452OT", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G98453VS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G98453VS] could be generated at this time" }, { "glytoucan_ac": "G98485VQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G65597BI]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 }, { "id": "G65597BI", "dp": 10 }, { "id": "G98485VQ", "dp": 10 } ], "links": [ { "target": "G98485VQ", "source": "G65597BI", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G65597BI", "source": "G36191CD", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98490BN", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G20815TK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G98490BN", "dp": 11 } ], "links": [ { "target": "G98490BN", "source": "G20815TK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98516BG", "notes": [], "error": "No pathways for [G98516BG] could be generated at this time" }, { "glytoucan_ac": "G98537XO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G98537XO] could be generated at this time" }, { "glytoucan_ac": "G98549NZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G00743WU]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G85542KD", "dp": 10 }, { "id": "G00743WU", "dp": 11 }, { "id": "G98549NZ", "dp": 11 } ], "links": [ { "target": "G98549NZ", "source": "G00743WU", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G00743WU", "source": "G85542KD", "residue_affected": { "residue_id": "N69", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G85542KD", "source": "G88461FF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98559XP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 } ], "links": [ { "target": "G98559XP", "source": "G18938DW", "residue_affected": { "residue_id": "N18", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98565KP", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G53485VW", "dp": 14 } ], "links": [ { "target": "G98565KP", "source": "G53485VW", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G53485VW", "source": "G18938DW", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98572JS", "notes": [], "error": "No pathways for [G98572JS] could be generated at this time" }, { "glytoucan_ac": "G98590PE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G43677TG", "dp": 8 }, { "id": "G72718TT", "dp": 9 }, { "id": "G52934AK", "dp": 10 }, { "id": "G76528ZS", "dp": 11 }, { "id": "G68946DB", "dp": 12 } ], "links": [ { "target": "G98590PE", "source": "G68946DB", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G68946DB", "source": "G76528ZS", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G76528ZS", "source": "G52934AK", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G52934AK", "source": "G72718TT", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72718TT", "source": "G43677TG", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G43677TG", "source": "G69411IG", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98602UY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20966TZ]", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G20966TZ", "dp": 9 }, { "id": "G98602UY", "dp": 9 } ], "links": [ { "target": "G98602UY", "source": "G20966TZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20966TZ", "source": "G08520NM", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98615GD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G90703DJ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G98615GD", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G98671GW", "notes": [], "error": "No pathways for [G98671GW] could be generated at this time" }, { "glytoucan_ac": "G98712QJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G20815TK]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G98712QJ", "dp": 11 } ], "links": [ { "target": "G98712QJ", "source": "G20815TK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98723AA", "notes": [], "error": "No pathways for [G98723AA] could be generated at this time" }, { "glytoucan_ac": "G98728LU", "notes": [], "error": "No pathways for [G98728LU] could be generated at this time" }, { "glytoucan_ac": "G98732ZL", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G98736SM", "notes": [], "error": "No pathways for [G98736SM] could be generated at this time" }, { "glytoucan_ac": "G98766GK", "notes": [ "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G12504XV", "dp": 9 } ], "links": [ { "target": "G98766GK", "source": "G12504XV", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G12504XV", "source": "G08520NM", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] } ] } , { "glytoucan_ac": "G98790NR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G05600OX]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G98790NR", "dp": 14 } ], "links": [] } , { "glytoucan_ac": "G98795XC", "notes": [], "error": "No pathways for [G98795XC] could be generated at this time" }, { "glytoucan_ac": "G98809PE", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 } ], "links": [ { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98852TR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G17909DH", "dp": 14 }, { "id": "G28957FB", "dp": 15 } ], "links": [ { "target": "G98852TR", "source": "G28957FB", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G28957FB", "source": "G17909DH", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17909DH", "source": "G18938DW", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98855LF", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G82312JY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G80858MF", "dp": 8 }, { "id": "G82312JY", "dp": 9 }, { "id": "G98855LF", "dp": 9 } ], "links": [ { "target": "G98855LF", "source": "G82312JY", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G82312JY", "source": "G80858MF", "residue_affected": { "residue_id": "N30", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G80858MF", "source": "G07483YN", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98862GW", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75049FP", "dp": 12 } ], "links": [ { "target": "G98862GW", "source": "G75049FP", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G75049FP", "source": "G99645NK", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G98894JN", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G84536BM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G98894JN", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G98899DA", "notes": [], "error": "No pathways for [G98899DA] could be generated at this time" }, { "glytoucan_ac": "G98906WL", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G98906WL] could be generated at this time" }, { "glytoucan_ac": "G98950NS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G99026RX", "notes": [], "error": "No pathways for [G99026RX] could be generated at this time" }, { "glytoucan_ac": "G99067GT", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G99074EO", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 } ], "links": [ { "target": "G99074EO", "source": "G11034PZ", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99078IR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G26018HD]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G26018HD", "dp": 12 }, { "id": "G99078IR", "dp": 12 } ], "links": [ { "target": "G99078IR", "source": "G26018HD", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G26018HD", "source": "G90870DG", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99129GB", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G66937TJ]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G99129GB", "dp": 8 } ], "links": [ { "target": "G99129GB", "source": "G66937TJ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99141XX", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G56549DH]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G01265XZ", "dp": 9 }, { "id": "G78803YD", "dp": 10 }, { "id": "G79809MM", "dp": 11 }, { "id": "G11034PZ", "dp": 12 }, { "id": "G56549DH", "dp": 13 }, { "id": "G99141XX", "dp": 13 } ], "links": [ { "target": "G99141XX", "source": "G56549DH", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G56549DH", "source": "G11034PZ", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G11034PZ", "source": "G79809MM", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79809MM", "source": "G78803YD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G78803YD", "source": "G01265XZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G01265XZ", "source": "G10219AA", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99154NV", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G76478FT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G76478FT", "dp": 11 }, { "id": "G99154NV", "dp": 11 } ], "links": [ { "target": "G99154NV", "source": "G76478FT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G76478FT", "source": "G78059CC", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99165YY", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G99182WQ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G64618XR]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G99182WQ", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G99204QC", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G79578JB", "dp": 12 }, { "id": "G53812BX", "dp": 13 }, { "id": "G78030KJ", "dp": 14 } ], "links": [ { "target": "G99204QC", "source": "G78030KJ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G78030KJ", "source": "G53812BX", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G53812BX", "source": "G79578JB", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G79578JB", "source": "G29857RC", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99225RS", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G52676LZ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G20956ZK", "dp": 8 }, { "id": "G88461FF", "dp": 9 }, { "id": "G72082VM", "dp": 10 }, { "id": "G59877NF", "dp": 11 }, { "id": "G32659RY", "dp": 12 }, { "id": "G52676LZ", "dp": 13 }, { "id": "G99225RS", "dp": 13 } ], "links": [ { "target": "G99225RS", "source": "G52676LZ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52676LZ", "source": "G32659RY", "residue_affected": { "residue_id": "N108", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [] }, { "target": "G32659RY", "source": "G59877NF", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G59877NF", "source": "G72082VM", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G72082VM", "source": "G88461FF", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G88461FF", "source": "G20956ZK", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G20956ZK", "source": "G07483YN", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99229VQ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G63166WT]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G63166WT", "dp": 12 }, { "id": "G99229VQ", "dp": 12 } ], "links": [ { "target": "G99229VQ", "source": "G63166WT", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G63166WT", "source": "G30302VM", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99242KO", "notes": [ "reducing end mismatch [o-D-GlcNAc]", "homologous pathway end-point [G17740GV]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G29857RC", "dp": 11 }, { "id": "G84376FR", "dp": 12 }, { "id": "G66282NU", "dp": 13 }, { "id": "G89877QI", "dp": 14 }, { "id": "G17740GV", "dp": 15 }, { "id": "G99242KO", "dp": 15 } ], "links": [ { "target": "G99242KO", "source": "G17740GV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G17740GV", "source": "G89877QI", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G89877QI", "source": "G66282NU", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G66282NU", "source": "G84376FR", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G84376FR", "source": "G29857RC", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G29857RC", "source": "G62504BU", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99257WS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G36191CD", "dp": 9 } ], "links": [ { "target": "G99257WS", "source": "G36191CD", "residue_affected": { "residue_id": "N49", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G36191CD", "source": "G66937TJ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99258WN", "notes": [], "error": "No pathways for [G99258WN] could be generated at this time" }, { "glytoucan_ac": "G99270AV", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G52663AD", "dp": 9 } ], "links": [ { "target": "G99270AV", "source": "G52663AD", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G52663AD", "source": "G10219AA", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99306JE", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G87457SB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G99306JE", "dp": 13 } ], "links": [] } , { "glytoucan_ac": "G99309EE", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G52080WL]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G66937TJ", "dp": 8 }, { "id": "G52080WL", "dp": 9 }, { "id": "G99309EE", "dp": 9 } ], "links": [ { "target": "G99309EE", "source": "G52080WL", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G52080WL", "source": "G66937TJ", "residue_affected": { "residue_id": "N53", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G66937TJ", "source": "G39213VZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99342HD", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 } ], "links": [ { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99356PZ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 } ], "links": [ { "target": "G99356PZ", "source": "G12398HZ", "residue_affected": { "residue_id": "N56", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99370TQ", "notes": [ "pathway start-point [G08520NM]" ], "error": "No pathways from [G08520NM] to [G99370TQ] could be generated at this time" }, { "glytoucan_ac": "G99372TR", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G30302VM]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G58667NI", "dp": 9 }, { "id": "G78059CC", "dp": 10 }, { "id": "G30302VM", "dp": 11 }, { "id": "G99372TR", "dp": 11 } ], "links": [ { "target": "G99372TR", "source": "G30302VM", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G30302VM", "source": "G78059CC", "residue_affected": { "residue_id": "N47", "pubchem_name": "NeuNGc", "anomer": "a", "absolute": "D", "form_name": "NeupNGc", "full_name": "α-D-NeupNGc" }, "effect": "Adds α-D-NeupNGc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G78059CC", "source": "G58667NI", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G58667NI", "source": "G12398HZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99382AP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G75143LK]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G75143LK", "dp": 11 }, { "id": "G99382AP", "dp": 11 } ], "links": [ { "target": "G99382AP", "source": "G75143LK", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G75143LK", "source": "G71013KY", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99393DF", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G99393DF] could be generated at this time" }, { "glytoucan_ac": "G99403QU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G55645TD]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G99403QU", "dp": 17 } ], "links": [] } , { "glytoucan_ac": "G99411XJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G12398HZ", "dp": 8 }, { "id": "G42672MA", "dp": 9 }, { "id": "G32305RZ", "dp": 10 }, { "id": "G10691MJ", "dp": 11 }, { "id": "G47782UT", "dp": 12 }, { "id": "G92359VA", "dp": 13 } ], "links": [ { "target": "G99411XJ", "source": "G92359VA", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G92359VA", "source": "G47782UT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G47782UT", "source": "G10691MJ", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G10691MJ", "source": "G32305RZ", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32305RZ", "source": "G42672MA", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G42672MA", "source": "G12398HZ", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G12398HZ", "source": "G07483YN", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99448WD", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G99465IE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 } ], "links": [ { "target": "G99465IE", "source": "G06131VP", "residue_affected": { "residue_id": "N54", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT2", "uniprot": "Q10981", "type": "GT", "species": "human" }, { "gene_name": "FUT1", "uniprot": "P19526", "type": "GT", "species": "human" }, { "gene_name": "Fut1", "uniprot": "O09160", "type": "GT", "species": "mouse" }, { "gene_name": "Fut2", "uniprot": "Q9JL27", "type": "GT", "species": "mouse" }, { "gene_name": "Sec1", "uniprot": "P97353", "type": "GT", "species": "mouse" } ] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99502WP", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G23546LY]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G99502WP", "dp": 12 } ], "links": [] } , { "glytoucan_ac": "G99503MW", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G06131VP]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G32201IL", "dp": 10 }, { "id": "G06131VP", "dp": 11 }, { "id": "G99503MW", "dp": 11 } ], "links": [ { "target": "G99503MW", "source": "G06131VP", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G06131VP", "source": "G32201IL", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G32201IL", "source": "G20030CU", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99505XE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G79609RF", "dp": 10 } ], "links": [ { "target": "G99505XE", "source": "G79609RF", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G79609RF", "source": "G20030CU", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99516QU", "notes": [], "error": "No pathways for [G99516QU] could be generated at this time" }, { "glytoucan_ac": "G99519QZ", "notes": [], "error": "No pathways for [G99519QZ] could be generated at this time" }, { "glytoucan_ac": "G99533GU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G10292TC", "dp": 15 }, { "id": "G99342HD", "dp": 16 }, { "id": "G28106CM", "dp": 17 } ], "links": [ { "target": "G99533GU", "source": "G28106CM", "residue_affected": { "residue_id": "N35", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G28106CM", "source": "G99342HD", "residue_affected": { "residue_id": "N14", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G99342HD", "source": "G10292TC", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G10292TC", "source": "G63889NK", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99568AR", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G86696LV]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G00176HZ", "dp": 10 }, { "id": "G90870DG", "dp": 11 }, { "id": "G98809PE", "dp": 12 }, { "id": "G73492AT", "dp": 13 }, { "id": "G63889NK", "dp": 14 }, { "id": "G76842ZR", "dp": 15 }, { "id": "G17155VX", "dp": 16 }, { "id": "G86696LV", "dp": 17 }, { "id": "G99568AR", "dp": 17 } ], "links": [ { "target": "G99568AR", "source": "G86696LV", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G86696LV", "source": "G17155VX", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G17155VX", "source": "G76842ZR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G76842ZR", "source": "G63889NK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G63889NK", "source": "G73492AT", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G73492AT", "source": "G98809PE", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G98809PE", "source": "G90870DG", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G90870DG", "source": "G00176HZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G00176HZ", "source": "G20030CU", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99595YZ", "notes": [], "error": "No pathways for [G99595YZ] could be generated at this time" }, { "glytoucan_ac": "G99603GB", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39089YD", "dp": 7 }, { "id": "G64669AQ", "dp": 8 } ], "links": [ { "target": "G99603GB", "source": "G64669AQ", "residue_affected": { "residue_id": "N485", "pubchem_name": "Xyl", "anomer": "b", "absolute": "D", "form_name": "Xylp", "full_name": "β-D-Xylp" }, "effect": "Adds β-D-Xylp", "enzymes": [] }, { "target": "G64669AQ", "source": "G39089YD", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G39089YD", "source": "G61751GZ", "residue_affected": { "residue_id": "N40", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [] } ] } , { "glytoucan_ac": "G99622IJ", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G43664YB]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G43664YB", "dp": 9 }, { "id": "G99622IJ", "dp": 9 } ], "links": [ { "target": "G99622IJ", "source": "G43664YB", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G43664YB", "source": "G24420RT", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99626QO", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G86377SM]", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G99626QO", "dp": 15 } ], "links": [] } , { "glytoucan_ac": "G99645NK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 } ], "links": [ { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99647DZ", "notes": [ "reducing end mismatch [x-D-GlcNAc]", "homologous pathway end-point [G03272YQ]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G21788RU", "dp": 12 }, { "id": "G03272YQ", "dp": 13 }, { "id": "G99647DZ", "dp": 13 } ], "links": [ { "target": "G99647DZ", "source": "G03272YQ", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G03272YQ", "source": "G21788RU", "residue_affected": { "residue_id": "N42", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT5", "uniprot": "Q11128", "type": "GT", "species": "human" }, { "gene_name": "FUT6", "uniprot": "P51993", "type": "GT", "species": "human" }, { "gene_name": "FUT4", "uniprot": "P22083", "type": "GT", "species": "human" }, { "gene_name": "FUT9", "uniprot": "Q9Y231", "type": "GT", "species": "human" }, { "gene_name": "FUT3", "uniprot": "P21217", "type": "GT", "species": "human" }, { "gene_name": "Fut9", "uniprot": "O88819", "type": "GT", "species": "mouse" }, { "gene_name": "Fut4", "uniprot": "Q11127", "type": "GT", "species": "mouse" } ] }, { "target": "G21788RU", "source": "G25520XG", "residue_affected": { "residue_id": "N41", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT11", "uniprot": "Q495W5", "type": "GT", "species": "human" }, { "gene_name": "FUT10", "uniprot": "Q6P4F1", "type": "GT", "species": "human" }, { "gene_name": "Fut11", "uniprot": "Q8BHC9", "type": "GT", "species": "mouse" }, { "gene_name": "Fut10", "uniprot": "Q5F2L2", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99651QK", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [G61684ET]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G61684ET", "dp": 12 }, { "id": "G99651QK", "dp": 12 } ], "links": [ { "target": "G99651QK", "source": "G61684ET", "residue_affected": [], "effect": "Reducing end modification (e.g., release of glycan)", "enzymes": [] }, { "target": "G61684ET", "source": "G25520XG", "residue_affected": { "residue_id": "N50", "pubchem_name": "Gal", "anomer": "a", "absolute": "D", "form_name": "Galp", "full_name": "α-D-Galp" }, "effect": "Adds α-D-Galp", "enzymes": [ { "gene_name": "ABO", "uniprot": "P16442", "type": "GT", "species": "human" }, { "gene_name": "Abo", "uniprot": "P38649", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99669MJ", "notes": [], "error": "No pathways for [G99669MJ] could be generated at this time" }, { "glytoucan_ac": "G99729IU", "notes": [ "reducing end mismatch [x-D-GlcpNAc]", "homologous pathway end-point [not found]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "DP error for glycan [not found] at the end of the path; no pathways generated" }, { "glytoucan_ac": "G99770NO", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G15103WJ", "dp": 12 } ], "links": [ { "target": "G99770NO", "source": "G15103WJ", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G15103WJ", "source": "G25520XG", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99796NW", "notes": [], "error": "No pathways for [G99796NW] could be generated at this time" }, { "glytoucan_ac": "G99801SM", "notes": [], "error": "No pathways for [G99801SM] could be generated at this time" }, { "glytoucan_ac": "G99808VS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G99808VS] could be generated at this time" }, { "glytoucan_ac": "G99829YW", "notes": [], "error": "No pathways for [G99829YW] could be generated at this time" }, { "glytoucan_ac": "G99858XP", "notes": [], "error": "No pathways for [G99858XP] could be generated at this time" }, { "glytoucan_ac": "G99866WK", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G69411IG", "dp": 7 }, { "id": "G24420RT", "dp": 8 }, { "id": "G46638GC", "dp": 9 }, { "id": "G62504BU", "dp": 10 }, { "id": "G20815TK", "dp": 11 }, { "id": "G10874QT", "dp": 12 }, { "id": "G00909PI", "dp": 13 }, { "id": "G38395YJ", "dp": 14 } ], "links": [ { "target": "G99866WK", "source": "G38395YJ", "residue_affected": { "residue_id": "N241", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [] }, { "target": "G38395YJ", "source": "G00909PI", "residue_affected": { "residue_id": "N12", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G00909PI", "source": "G10874QT", "residue_affected": { "residue_id": "N33", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G10874QT", "source": "G20815TK", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20815TK", "source": "G62504BU", "residue_affected": { "residue_id": "N28", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B3GALT2", "uniprot": "O43825", "type": "GT", "species": "human" }, { "gene_name": "B3GALT5", "uniprot": "Q9Y2C3", "type": "GT", "species": "human" }, { "gene_name": "B3galt5", "uniprot": "Q9JI67", "type": "GT", "species": "mouse" }, { "gene_name": "B3gal2", "uniprot": "O54905", "type": "GT", "species": "mouse" } ] }, { "target": "G62504BU", "source": "G46638GC", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G46638GC", "source": "G24420RT", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G24420RT", "source": "G69411IG", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G69411IG", "source": "G61751GZ", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99891PR", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G10219AA", "dp": 8 }, { "id": "G20030CU", "dp": 9 }, { "id": "G08863NS", "dp": 10 }, { "id": "G99645NK", "dp": 11 }, { "id": "G75185NU", "dp": 12 }, { "id": "G18938DW", "dp": 13 }, { "id": "G73775WR", "dp": 14 }, { "id": "G37990ZT", "dp": 15 } ], "links": [ { "target": "G99891PR", "source": "G37990ZT", "residue_affected": { "residue_id": "N38", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G37990ZT", "source": "G73775WR", "residue_affected": { "residue_id": "N34", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G73775WR", "source": "G18938DW", "residue_affected": { "residue_id": "N16", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G18938DW", "source": "G75185NU", "residue_affected": { "residue_id": "N10", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G75185NU", "source": "G99645NK", "residue_affected": { "residue_id": "N8", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G99645NK", "source": "G08863NS", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G08863NS", "source": "G20030CU", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G20030CU", "source": "G10219AA", "residue_affected": { "residue_id": "N7", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT4B", "uniprot": "Q9UQ53", "type": "GT", "species": "human" }, { "gene_name": "MGAT4A", "uniprot": "Q9UM21", "type": "GT", "species": "human" }, { "gene_name": "MGAT4C", "uniprot": "Q9UBM8", "type": "GT", "species": "human" }, { "gene_name": "Mgat4b", "uniprot": "Q812F8", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4c", "uniprot": "Q9D306", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat4a", "uniprot": "Q812G0", "type": "GT", "species": "mouse" } ] }, { "target": "G10219AA", "source": "G39213VZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99897FQ", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G39213VZ", "dp": 7 }, { "id": "G67045LB", "dp": 8 } ], "links": [ { "target": "G99897FQ", "source": "G67045LB", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G67045LB", "source": "G39213VZ", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] }, { "target": "G39213VZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99927HL", "notes": [], "error": "No pathways for [G99927HL] could be generated at this time" }, { "glytoucan_ac": "G99935CU", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 }, { "id": "G99969SS", "dp": 10 } ], "links": [ { "target": "G99935CU", "source": "G99969SS", "residue_affected": { "residue_id": "N469", "pubchem_name": "sulfate", "anomer": "n", "absolute": "n", "form_name": "sulfate", "full_name": "-n-sulfate" }, "effect": "Adds -n-sulfate", "enzymes": [] }, { "target": "G99969SS", "source": "G13151XE", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99943EE", "notes": [ "pathway start-point [G61751GZ]" ], "error": "No pathways from [G61751GZ] to [G99943EE] could be generated at this time" }, { "glytoucan_ac": "G99954ZJ", "notes": [ "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G07483YN", "dp": 7 }, { "id": "G51490BW", "dp": 8 }, { "id": "G30159WR", "dp": 9 }, { "id": "G71013KY", "dp": 10 }, { "id": "G25520XG", "dp": 11 }, { "id": "G20096RP", "dp": 12 } ], "links": [ { "target": "G99954ZJ", "source": "G20096RP", "residue_affected": { "residue_id": "N17", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST3GAL6", "uniprot": "Q9Y274", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL4", "uniprot": "Q11206", "type": "GT", "species": "human" }, { "gene_name": "ST3GAL3", "uniprot": "Q11203", "type": "GT", "species": "human" }, { "gene_name": "St3gal3", "uniprot": "P97325", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal4", "uniprot": "Q91Y74", "type": "GT", "species": "mouse" }, { "gene_name": "St3gal6", "uniprot": "Q8VIB3", "type": "GT", "species": "mouse" } ] }, { "target": "G20096RP", "source": "G25520XG", "residue_affected": { "residue_id": "N13", "pubchem_name": "NeuNAc", "anomer": "a", "absolute": "D", "form_name": "NeupNAc", "full_name": "α-D-NeupNAc" }, "effect": "Adds α-D-NeupNAc", "enzymes": [ { "gene_name": "ST6GAL1", "uniprot": "P15907", "type": "GT", "species": "human" }, { "gene_name": "ST6GAL2", "uniprot": "Q96JF0", "type": "GT", "species": "human" }, { "gene_name": "St6gal2", "uniprot": "Q76K27", "type": "GT", "species": "mouse" }, { "gene_name": "St6gal1", "uniprot": "Q64685", "type": "GT", "species": "mouse" } ] }, { "target": "G25520XG", "source": "G71013KY", "residue_affected": { "residue_id": "N6", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G71013KY", "source": "G30159WR", "residue_affected": { "residue_id": "N3", "pubchem_name": "Gal", "anomer": "b", "absolute": "D", "form_name": "Galp", "full_name": "β-D-Galp" }, "effect": "Adds β-D-Galp", "enzymes": [ { "gene_name": "B4GALT3", "uniprot": "O60512", "type": "GT", "species": "human" }, { "gene_name": "B4GALT1", "uniprot": "P15291", "type": "GT", "species": "human" }, { "gene_name": "B4GALT2", "uniprot": "O60909", "type": "GT", "species": "human" }, { "gene_name": "B4galt2", "uniprot": "Q9Z2Y2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt3", "uniprot": "Q91YY2", "type": "GT", "species": "mouse" }, { "gene_name": "B4galt1", "uniprot": "P15535", "type": "GT", "species": "mouse" } ] }, { "target": "G30159WR", "source": "G51490BW", "residue_affected": { "residue_id": "N5", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT2", "uniprot": "Q10469", "type": "GT", "species": "human" }, { "gene_name": "Mgat2", "uniprot": "Q921V5", "type": "GT", "species": "mouse" } ] }, { "target": "G51490BW", "source": "G07483YN", "residue_affected": { "residue_id": "N11", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT3", "uniprot": "Q09327", "type": "GT", "species": "human" }, { "gene_name": "Mgat3", "uniprot": "Q10470", "type": "GT", "species": "mouse" } ] }, { "target": "G07483YN", "source": "G61751GZ", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99956MJ", "notes": [ "reducing end mismatch [o-D-GlcolNAc]", "homologous pathway end-point [G46767VX]", "glycan is core-fucosylated", "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G99956MJ", "dp": 18 } ], "links": [] } , { "glytoucan_ac": "G99969SS", "notes": [ "glycan is core-fucosylated", "pathway start-point [G08520NM]" ], "error": "", "nodes": [ { "id": "G08520NM", "dp": 8 }, { "id": "G13151XE", "dp": 9 } ], "links": [ { "target": "G99969SS", "source": "G13151XE", "residue_affected": { "residue_id": "N15", "pubchem_name": "Fuc", "anomer": "a", "absolute": "L", "form_name": "Fucp", "full_name": "α-L-Fucp" }, "effect": "Adds α-L-Fucp", "enzymes": [ { "gene_name": "FUT8", "uniprot": "Q9BYC5", "type": "GT", "species": "human" }, { "gene_name": "Fut8", "uniprot": "Q9WTS2", "type": "GT", "species": "mouse" } ] }, { "target": "G13151XE", "source": "G08520NM", "residue_affected": { "residue_id": "N29", "pubchem_name": "GalNAc", "anomer": "b", "absolute": "D", "form_name": "GalpNAc", "full_name": "β-D-GalpNAc" }, "effect": "Adds β-D-GalpNAc", "enzymes": [ { "gene_name": "B4GALNT4", "uniprot": "Q76KP1", "type": "GT", "species": "human" }, { "gene_name": "B4GALNT3", "uniprot": "Q6L9W6", "type": "GT", "species": "human" }, { "gene_name": "B4galnt3", "uniprot": "A0A1D5RMF7", "type": "GT", "species": "mouse" }, { "gene_name": "B4galnt4", "uniprot": "Q766D5", "type": "GT", "species": "mouse" } ] } ] } , { "glytoucan_ac": "G99997WS", "notes": [ "pathway start-point [G61751GZ]" ], "error": "", "nodes": [ { "id": "G61751GZ", "dp": 6 }, { "id": "G74090KZ", "dp": 7 } ], "links": [ { "target": "G99997WS", "source": "G74090KZ", "residue_affected": { "residue_id": "N201", "pubchem_name": "Fuc", "anomer": "a", "absolute": "D", "form_name": "Fucp", "full_name": "α-D-Fucp" }, "effect": "Adds α-D-Fucp", "enzymes": [ { "gene_name": "abiotic", "uniprot": "abiotic", "type": "", "species": "no known organism" } ] }, { "target": "G74090KZ", "source": "G61751GZ", "residue_affected": { "residue_id": "N9", "pubchem_name": "GlcNAc", "anomer": "b", "absolute": "D", "form_name": "GlcpNAc", "full_name": "β-D-GlcpNAc" }, "effect": "Adds β-D-GlcpNAc", "enzymes": [ { "gene_name": "MGAT5", "uniprot": "Q09328", "type": "GT", "species": "human" }, { "gene_name": "MGAT5B", "uniprot": "Q3V5L5", "type": "GT", "species": "human" }, { "gene_name": "Mgat5", "uniprot": "Q8R4G6", "type": "GT", "species": "mouse" }, { "gene_name": "Mgat5b", "uniprot": "Q765H6", "type": "GT", "species": "mouse" } ] } ] } ] }